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Peptides in Medical News

Study reveals current multi-component vaccines may need reworking

... If not, can we make changes to useful peptides that make them the center of the immune system's ... careful decisions about which disease-causing peptides attract attention. Upon encountering an invader, ... II proteins inside the dendritic cells present peptides on the cell's surface for consideration by T ...

Best New Product Awards Winners Named at Molecular Medicine Tri-Conference

... Biological Samples & Reagents ClearPoint peptides by AnaSpec Chemistry Pipeline Pilot ... Best New Product Award Winners ClearPoint peptides By spiking protein tryptic digests with internal ... or universal positions, ClearPoint™ peptides are an ideal solution for absolute protein ...

American Chemical Society's Weekly PessPac -- Feb. 18, 2009

... the scientists identified several different peptides in boiled and fried eggs that act as potent ACE ... in the stomach and small intestine produce these peptides from eggs. Fried eggs had the highest ACE ... "Angiotensin I Converting Enzyme Inhibitory peptides from Simulated in Vitro Gastrointestinal ...

Genes That Control Body's Salt Levels Are Identified

... gene variants cause higher levels of natriuretic peptides and therefore are related to blood pressure." Natriuretic peptides are compounds that help the body get rid of salt. ... looked at variants of two genes for these peptides -- atrial natriuretic peptide (ANP) and B-type ...

Merck Serono and Apitope Announce Licensing Agreement on Novel Peptide Therapeutics for the Treatment of Multiple Sclerosis

... Apitope for research on other novel therapeutic peptides for the treatment of MS. Under the terms of ... Serono." ATX-MS-1467 consists of four short peptides that are derived from myelin basic protein, a key ... evidence showing that soluble, synthetic peptides can reinstate tolerance and selectively attenuate ...

Frost & Sullivan Lauds Toscana Biomarkers' Outstanding Contributions to the R&D of Novel Biomarkers for the Diagnosis of Autoimmune Diseases

... that the incorporation of synthetically modified peptides for the validation and discovery of biomarkers ... disease progression and activity. "Antigenic peptides that can selectively and specifically recognise ... "The synthetic post-translationally modified peptides get well recognized by the auto-antibodies, ...

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Peptides in Medical Technology

Raptor Pharmaceuticals Receives Notices of Allowance for Two NeuroTrans(TM) Patent Applications

... generally cover the use of its proprietary RAP peptides in the delivery of diagnostic and therapeutic ... minimally invasive way by conjugating them to RAP peptides engineered by Raptor. Hundreds of ... the use of our NeuroTrans(TM) CNS targeting peptides and the extensive range of potential uses of ...

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

... a robust portfolio of small, novel oncolytic peptides to selectively destroy cancer cells that express ... on their surfaces. The positively charged peptides disrupt the negatively charged membranes of the ... These drug candidates, called membrane-disrupting peptides (MDPs), selectively kill cancer cells, including ...

Are Muramyl Peptides the Magic Bullet in Probiotics?

... effects of lysed probiotics are due to muramyl peptides in the cell fragments. "European doctors went ... a new bio-technology. In simple terms, muramyl peptides regulate the correlation between different ... system. When probiotics are lysed, the muramyl peptides become bio-available. The ...

Raptor Pharmaceuticals Provides Update of Product Programs

... first year of the collaboration, a number of RAP peptides were tested for their ability to cross the BBB. ... HepTide(TM) utilizes engineered RAP-based peptides conjugated to drugs to target their delivery to ... In neurodegenerative diseases, engineered RAP peptides called NeuroTrans(TM) are currently undergoing ...

Replikins LLC Finds West Nile Virus Replikin Count Has Reached Its Highest Recorded Value

... has discovered a new group of virus structural peptides within virus proteins, called replikins, ... measures the concentration of these specific peptides in virus proteins (Replikin Count(TM)). ... to come. Replikins LLC analysis of the West Nile peptides has provided advanced warning of the increase of ...

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

... PTHrP (parathyroid hormone-related protein) and its analogs are critical peptides for promoting new bone formation. Though they act through the same ... play an important role in regulating bone remodeling in adults. While both peptides have demonstrated the ability to increase bone mineral density and bone ...

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Peptides in Medical Products

ALS, Total ELISA Test

Description:... vivo. However, ALS may also be capable of IGF-independent interaction with IGFBP-3 and as such modulate the binding capacity of IGFBP-3 for the IGF peptides [11]. Jones JI et al. Endocrin Rev 16:3-34, 1995 Rosenfeld RG et al. Recent Prog Horm Res 46:99-163, 1990 Shimesaki S et al. Prog Growth ...
Company:Diagnostic Systems Laboratories, Inc.

Dynabeads® MyOne™ Streptavidin T1

Features:... Low charged and neutral beads, optimal for binding of proteins, peptides and antibodies Their small but uniform size presents a high surface area per mg beads and a correspondingly high capacity for the target molecule ...
Company:Dynal Biotech, LLC
Peptides in Medical Definition

Thymocyte

... in thymocytes with a high affinity for self peptides or MHC. This eliminates cells which would direct ... able to recognise short protein sequences ( peptides ) that are presented on MHC . During the double ... thymocytes with a high affinity for binding self peptides presented on MHC class I or class II are induced ...
Peptides in Medical Dictionary

Amino acids

... acids : The building blocks of polyp eptides and protein s. Search All of MedicineNet For: search help Printer-Friendly Format ... Amino Acids peptides Peptides Protein s Glycoproteins Amino Acid (a.a.) Monoamine Small organic molecule containing both a carboxyl group and an amino group bonded ...

Delta

... delta -9-tetrahydrocannabinol (THC), ... T-cells, the antigen peptides must be presented on Class II MHC, and in the case of killer T-cells , the antigen peptides must be presented on Class I MHC. The T- cell antigen receptor ...

ELISA

... to as an ELISA ( enzyme -linked immunosorbent assay), will, when positive, usually lead to a second test called the Western blot. Casein peptides are absorbed through the intestine and collect in the kidney s. These antibodies can be detected with a relatively simple, highly accurate blood ...

Polyp

... loss Thirst ( polydipsia ) Extreme hunger ( polyp hagia) Excessive urination ( polyuria ) Weakness or tiredness ... Polyp eptide Many peptides joined together. For example, insulin . Protein A molecule composed of many amino acids and with a complex structure. For example, ...

Smooth muscle

... atrophy . Prostaglandins are hormone -like substances that can stimulate contracitility of the smooth muscle s in the body. Kinins are peptides that can act on smooth muscle s and nerve endings. They lack the usual amount of smooth muscle tissue and elastin, a fibrous connective ...
Peptides in Biological News

U Alberta researcher in same group as Darwin and Hawking

... that centers on the identification of antibiotic peptides in bacteria. Antibiotic peptides play an important role in food preservation and ... such as combating hospital-acquired infections. peptides are 1,000 to 1 million times more active than ...

Scientists develop method for comprehensive proteome analysis

... into smaller peptides, then separation of the peptides based on electrostatic charge using strong anionic exchange chromatography. The peptides were further separated by molecular weight using ... liquid chromatography. Each of the individual peptides was detected and identified using mass ...

Scripps research team identifies key molecules that inhibit viral production

... new study, Strosberg and his colleagues describe peptides (molecules of two or more amino acids) derived ... protein of hepatitis C. The team found that these peptides inhibit not only dimerization of the core protein ... research, however, led to the discovery of two peptides that inhibited HCV production by 68 percent and ...

Peptides-on-demand: McGill researcher's radical new green chemistry makes the impossible possible

... discovered an entirely new way of synthesizing peptides using simple reagents, a process that would be ... of the National Academy of Sciences (PNAS), peptides are short oligomer and polymer substances made up ... themselves composed of longer chains of peptides. peptides are enormously important to biological and ...

Texas Medical Center researchers win collaborative grants

... treatments. Yang and Barron explained that peptides small strings of amino acids are unable to ... their research will be to see if such fullerene peptides can block the growth of cancer cells in mice. "Hopefully, we can establish the fullerene peptides as a type of therapeutic agent to cure ...

Discovery of natural compounds that could slow blood vessel growth

... growth." To identify short protein fragments peptides that can block blood vessel growth, the team started by looking at 40 known peptides that have been studied and characterized by other ... assumption that the antivessel activity of these peptides can be attributed to similar features that are ...

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Peptides in Biological Technology

New drugs faster from natural compounds: A UC San Diego breakthrough

... to rapidly characterize ring-shaped nonribosomal peptides (NRPs)a class of natural compounds of intense ... ) Nonribosomal peptides (NRPs) often serve as chemical defenses for the ... called mass spectrometers that blast nonribosomal peptides apart and determine their sizes. Two ...

New method may accelerate drug discovery for difficult diseases like Parkinson's

... proteins that occur at these surfaces. Cyclic peptides have the ability to bind where traditional drugs ... Kritzer created a vast "library" of cyclic peptides containing various amino acid combinations. He then inserted the cyclic peptides into cells of a well-established yeast model of ...

Novel drug discovery tool could identify promising new therapies for Parkinson's disease

... called cyclic peptides. Two of the cyclic peptides had a protective effect on the yeast cells and on ... her team tested whether yeast could make cyclic peptides that would save them from alpha-synuclein's toxicity. Cyclic peptides are fragments of protein that connect end-to-end ...

DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology

... that promote the intestinal absorption of peptides and other sensitive drugs that cannot otherwise ... a large number of water-soluble drugs including peptides that are poorly permeable, resulting in increased ... structurally prevent the rapid inactivation of peptides by enzymes in the upper gastrointestinal tract. ...

Organic, Preservative-Free Skin Care Products from Dermaheal Now Available in the United States

... the finest, freshest ingredients, the effective peptides and nanotechnology delivery system of Dermaheal 2 ... The product's active ingredients are proprietary peptides proven to stimulate skin cells to build ... delivery system of nanotechnology, the active peptides are embedded within tiny capsules called ...

Publication on 'Tregitopes' in Blood Journal of October 2008

... Epi-13(TM) Epi-13(TM) is a group of "Tregitope" peptides that induce the body's own natural regulatory T ... T cell epitope mapping, the selection of target peptides from any protein sequence, is a powerful resource ... protein therapeutics. EpiVax research shows that peptides chosen by EpiMatrix(TM) software are highly ...

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Peptides in Biological Products

QXL 520 C2 maleimide from AnaSpec

Description:... proteins, the single isomers are increasingly preferred for labeling peptides and nucleotides because they give better resolution in HPLC purification ... processes. 5-TAMRA is more often used than 6-TAMRA for labeling peptides and proteins. 6-TAMRA is predominately used for labeling nucleotides and ...
Company:AnaSpec

ATTO-TAG CBQCA Amine-Derivatization Kit from Molecular Probes (Invitrogen)

Description:... Unlike OPA and NDA, ATTO-TAG CBQCA will also react with hydrophilic peptides and amino sugars. The resulting products of CBQCA highly fluorescent ... FQ for the solid-phase derivatization of dilute solutions (10-8 M) of peptides that have been immobilized on Immobilon-CD membranes. This method permits ...
Company:Molecular Probes (Invitrogen)

ATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) from Molecular Probes (Invitrogen)

Description:... Unlike OPA and NDA, ATTO-TAG CBQCA will also react with hydrophilic peptides and amino sugars. The resulting products of CBQCA ? highly fluorescent ... FQ for the solid-phase derivatization of dilute solutions (10-8 M) of peptides that have been immobilized on Immobilon-CD membranes. This method permits ...
Company:Molecular Probes (Invitrogen)

ATTO-TAG FQ Amine-Derivatization Kit from Molecular Probes (Invitrogen)

Description:... Unlike OPA and NDA, ATTO-TAG CBQCA will also react with hydrophilic peptides and amino sugars. The resulting products of CBQCA ? highly fluorescent ... FQ for the solid-phase derivatization of dilute solutions (10-8 M) of peptides that have been immobilized on Immobilon-CD membranes. This method permits ...
Company:Molecular Probes (Invitrogen)

Peptides from Thermo Scientific

Description:... for solid support synthesis and synthesis in solution. Our Functional peptides are controlled by Mass Spectrometry and analytical HPLC at no extra cost, ... Our advanced ordering platform allows you to order your custom peptides on-line via our fully automated ....
Company:Thermo Scientific

MIDAS TRAQ System with 4000 Q TRAP LC/MS/MS System from Applied Biosystems

Description:... assay development hasslesthere is no need for protein standards, synthetic peptides or antibodies. Optimize the process of method development with unique ... or protein sequences. It also enables you to rapidly identify the best peptides for any sequence-defined protein target before you need to use synthetic ...
Company:Applied Biosystems

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Peptides in Biological Definition

Major histocompatibility complex

... interaction is that T cells should ignore self peptides while reacting appropriately to the foreign peptides. Foreign peptides that provoke an immune response are termed ... domains, α 1 , α 2 , which present peptides derived from cytosolic proteins to the immune ...

Neurotransmitter

... into small-molecule transmitters and neuroactive peptides . Around 10 small-molecule neurotransmitters are ... in autonomic neurons. Over 50 neuroactive peptides have been found, among them hormones such as LH ... by second messenger systems. Neuroactive peptides are synthesized in the neuron's soma and are ...

Peptide

... peptides (from the Greek ... a lone pair of electrons available for bonding. peptides (like proteins) occur in nature and are ... of which are not yet understood. Antimicrobial peptides generally disrupt the membranes of a target ...

Peptide

... peptides (from the Greek ... a lone pair of electrons available for bonding. peptides (like proteins) occur in nature and are ... of which are not yet understood. Antimicrobial peptides generally disrupt the membranes of a target ...

Amino acid

... biochemical building blocks. They form short polymer chains called peptides or polypeptides which in turn form structures called proteins . ... together with unsaturated amino acids in lantibiotics (antibiotic peptides of microbial origin). 1-Aminocyclopropane-1-carboxylic acid ( ACC ) is a ...

Proteome

... proteomics. Mass mapping identifies a protein by cleaving it into short peptides and then deduces the protein's identity by matching the observed peptide ... on the other hand, can get sequence information from individual peptides by isolating them, colliding them with a nonreactive gas, and then ...

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Peptides in Biological Dictionary

Peptides

... peptides are short polymers formed from the linking, in a ... amide bond or a peptide bond. Antimicrobial peptides are an evolutionarily conserved component of ... in Custom Peptide Synthesis, Services Amylin peptides , Trojan ...

Peptide

... peptides are short polymers formed from the linking, in a ... in Custom Peptide Synthesis, Services Amylin peptides , Trojan peptides , Oxygen Peptide , ... Custom DNA, ...

Peptide-binding groove

... of the ... ensconced in the MHC peptide - binding groove . Longer peptides are better ... The structure of the peptide binding groove , ...... The peptide binding groove of MHCII molecules is open, binding peptides in a ... ...

Peptide Bond

... molecule, thereby releasing a molecule of water (H2O). This is ... peptides are short polymers formed from the linking, in a defined order, of α-amino ... of a peptide bond from two amino acids, a ... 1. Peptide Bonds , peptides and Proteins. Proteins are sometimes called Polypeptides, ... (See Lecture ...

Spliceosome

... The spliceosome is comprised of five small nuclear RNAs (snRNAs)—U1, U2, U4, U5, ... In determining the list of spliceosome proteins, we used peptides that ... Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all ...

Signal Sequence

... secretion ... Signal peptide A signal peptide is a short (3-60 amino acids long) peptide chain ... sources refer to signal peptides as only the pre- sequence that targets the ... The signal sequence is immediately cleaved from the polypeptide once it has been ... This ...

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Other Contents
(Date:7/10/2014)... News) -- Teens who are sensitive to light or ... emotional symptoms such as anxiety and depression, a new ... may exacerbate issues teens experience after concussion may help ... decisions about when to return to play and what ... authors Lisa Koehl and Dong Han, of the University ...
(Date:7/10/2014)... HealthDay Reporter THURSDAY, July 10, 2014 (HealthDay ... regularly between outspoken celebrities or loudmouth pundits -- too much ... study suggests. High amounts of Twitter use can lead ... in a long-term relationship, according to findings from an online ... can lead to cheating and breakups, the researchers concluded, although ...
(Date:7/10/2014)... responders felt better prepared to respond to an active ... a new study in the journal Prehospital and ... specifically examine the EMS provider comfort level with respect ... yet been neutralized or working with law enforcement personnel ... High School shooting, the Virginia Tech campus shooting, the ...
(Date:7/10/2014)... PHILADELPHIA Reducing the amount of alcoholic beverages ... health, including a reduced risk of coronary heart ... pressure, according to a new multi-center study published ... the Perelman School of Medicine at the University ... previous studies which suggest that consuming light-to-moderate amounts ...
(Date:7/10/2014)... Department of Health and Human Services (HHS) has announced ... Center Seidman Cancer Center totaling $4.7 million to support ... patients with complex cancer. , Titled "Evidence-Conformant Oncology ... at UH to enhance care for adult cancer patients ... high health care utilization. , "We believe ...
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(Date:7/10/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/h7h8lq/gesture ... "Global Gesture Recognition & Touch-Less Sensing (2D, 3D, ... report to their offering ... & Touch-Less Sensing Market to Grow Exponentially. Touch-less ... but the companies were unable to leverage this ...
(Date:7/10/2014)... Fingerprint Cards, (FPC,s) new mobile touch ... Asian OEM has selected FPC1021 for a flagship model with ...   FPC is proud to announce this DW ... for start of mass production in August 2014. FPC has ... delivery in the first half of July. The OEM wants ...
(Date:7/10/2014)... to the large, mainly tropical flowering plant family Melastomataceae (Meadow ... family rely on bees for their pollination. Only about 100 ... The flowers of Axinaea appear in clusters of ... the different species are pink, yellow, orange or red. The ... colours of their bulbous appendages. The pollination mechanism of ...
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