Epstein-Barr virus protein crucial to its role in blood cancers
...ar case of EBV-driven B-cell lymphoma. The use of peptides to block the interaction between this essential EBV protein and the specific pathway in human B cells is currently underway. Initial studies show that the growth of EBV-associated cancer cells can be inhibited in tissue-culture assays. The investigat...Defensins neutralize anthrax toxin
...ar case of EBV-driven B-cell lymphoma. The use of peptides to block the interaction between this essential EBV protein and the specific pathway in human B cells is currently underway. Initial studies show that the growth of EBV-associated cancer cells can be inhibited in tissue-culture assays. The investigat...To control germs, scientists deploy tiny agents provocateurs
...ony by continuously exchanging small molecules and peptides - a process known as quorum sensing. Past a certain density threshold, the colonies unite to initiate group behaviors, such as biofilm formation. Attempting to manipulate quorum sensing in both plant and animal bacteria, Blackwell and her team are d...Product improves peptide identification for proteomics research
...ence researchers to identify 60 to 80 percent more peptides than preceding models in proteomics applications, such as protein identification and biomarker discovery, potentially leading to a better understanding of diseases like cancer and speeding drug development efforts. The Agilent 1100 Series LC/MSD Trap...Newly Discovered 'Branding' Process Helps Immune System Cells Pick Their Fights
...nue's group showed that this chemical modifies the peptides presented by antigen-presenting cells in several d...rious types of T cells would react to the modified peptides shown to them by antigen-presenting cells. Unanue's group is working to substantiate their findings...Peptide Synthesis from Sigma-Genosys
...PLC analyses to verify composition and purity. All peptides are shipped lyophilized and as gross weight. Delivery Actual processing time is dependent on the peptide sequence, length and modifications. Please consult Sigma-Genosys for a production estimate of your peptide. Estimated delivery times are st...ProteinChip beta-amyloid multipeptide detection Kit from Ciphergen
...Chip Systems, makes detecting a variety of amyloid peptides more straightforward and faster than ever before. - Clinical neuroscience proteomics applications - Monitor beta-amyloid expression after drug treatment - Correlate beta-amyloid peptide levels with disease progression - Evaluate mechanisms of Alzheim...ProteoSpin Micro CBED Kit from Norgen Biotek Corporation
...ge mechanism, a broad size range of proteins, from peptides to antibodies can be processed. Proteins bind while salts are discarded in flowthrough - SiC has an inherent low affinity for salt, but high affinity for proteins, providing salt removal and buffer exchange simultaneously. Suitable for downstream app...Ph.D. Peptide Display Cloning System from New England Biolabs
...pIII fusion, resulting in a valency of 5 displayed peptides per virion. The use of a phage vector, rather than a phagemid, simplifies the intermediate amplification steps, since neither antibiotic selection nor helper phage superinfection are required. Since displayed proteins longer than 20-30 amino acids ha......s (digestion & analysis) Aliquoting - order your peptides pre-aliquoted for convenience. Rapid, Cost-Effective Peptide Synthesis...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
... We obtained partial sequences from 23 peptides that were derived from two independent exp...six reading frames (tBLASTn). At least nine of the peptides were identified in partial sequences from the four EST cDNAs ( Figure 1 ). However, ...Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling
.... Conclusions Antibodies raised against specific peptides or fusion proteins can be used tospecifically target receptor protein subunits and to localize, quantify andcharacterize receptor protein subunits in tissues and cell lines. Stratagene nowoffers sequence-specific antibodies against NR2A, NR2B and NR2...Epitope-Tagging Vectors for Functional Analysis in Yeast
...tors also contain DNA sequences coding for epitope peptides that can be specifically recognized by monoclonal antibodies. A sequence for the FLAG epitope (DYKDDDDK 7 ) is located in the MCS downstream of the GAL1 promoter; a sequence for the c-myc epitope (EQKLISEEDL 8 ) ...Luminol-enhanced Assay for Superoxide Anion (O2 face="Symbol" )
...oglobulin G (Fc receptors) or bacterial formylated peptides (f-met-leu-phe receptors), which are stimulated by their specific agonists. The activated receptor triggers the production or activation of NADPH oxidase, leading to the production of superoxide anion. Superoxide anion is subsequently released into t...TKB1 Cells Identify Receptor Tyrosine Kinase Interacting Proteins
...bodies. Alternatively, phosphotyrosine-containing peptides that are chemicallysynthesized can also be used to yield similar results. However, syntheticpeptide reagents are expensive, nonrenewable, and require prior immobilizationfor such an assay (e.g., biotinylation or chemical crosslinking to a supportmatr...Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis
...acked. The damage is done by small proinflammatory peptides called proinflammatory cytokines and chemokines. O... introducing engineered genes based on the culprit peptides into the body. When the patient's immune system sees these genes as outside invaders, it produces it......breast milk. Their report said biologically active peptides in human milk may influence brain growth as well as the high levels of long chain polyunsaturated fatty acids....DNA biochip for genetic screening
...ly DNA, but other types of molecules, such as RNA, peptides or libraries of organic molecules. Other prevalent technologies do not have the same potential and capabilities as ours.” Gao and her team plan to make the biochips available for fields such as genomics, proteomics, chemical genetics and other new a...Hidden influenza virus protein found
...g through bits and pieces of “junk” peptides. Junk peptides are short protein molecules the virus creates once... goes wary, Yewdell explains. In other words, junk peptides result from genetic mistakes. The immune system cells of mice, in fact, did recognise one of the pe......ngs demonstrate the clinical significance of these peptides in humans, and suggest that a medication containing or inducing the peptides may one day be used to fight the infections that plague millions of atopic dermatitis patients. "T...Ceragenix Compound Shows Promise for Treating Lethal Cystic Fibrosis Infections
...ore effective than positively chargedantibacterial peptides (LL-37) against a multidrug resistant strainof Pse... the presence of naturally occurring antimicrobial peptides suchas LL-37 found in the lung fluid which form part of the body'sinnate immune system. These positi......pplicable to a variety of therapeutic proteins and peptides thatsuffer from weak durability and hence dictate short injectionfrequencies," said Shai Novik, Modigene's President. "We are movingforward with our preparations for GMP production of our leadprotein candidates and initiation of clinical trials there...New Flu Vaccine from PepTcell Could Provide Immunity Against All Strains of Influenza Virus
...are highlyconserved across strains, and that these peptides are naturallypresented on the surface of flu-infec...f, Wilson Caparros-Wanderly: Syntheticmultiepitope peptides identified in silico induce protectiveimmunity against multiple influenza serotypes. European Journa...New Flu Vaccine From PepTcell Could Provide Immunity Against All Strains of Influenza Virus
...are highlyconserved across strains, and that these peptides are naturallypresented on the surface of flu-infec...f, Wilson Caparros-Wanderly: Syntheticmultiepitope peptides identified in silico induce protectiveimmunity against multiple influenza serotypes. European Journa...