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Peptide in Medical News

Photos: Lumixyl(TM) Enters the Market to Improve the Appearance of Hyperpigmentation without Irritation and Side Effects

... a non-toxic, non-irritating, synthetic peptide technology shown to significantly help improve ... Lumixyl's ground-breaking technology is the only peptide shown to measurably promote healthy skin function ... skin that was treated with the Lumixyl peptide expressed a reduced production of melanin by as ...

Tips from the journals of the American Society for Microbiology

... antibodies that target a gastrin-releasing peptide which is known to play a key role in cancer ... and Vaccine Immunology . Gastrin-releasing peptide (GRP) is an important human peptide that regulates gastric acid secretion and motor ...

Caltech chemists say antibody surrogates are just a 'click' away

... group at one end. The alkyne group on the added peptide can potentially chemically react with the azide group of the library's peptides, to create a new peptide that is now two segments long. However, the reaction can only occur when the second peptide comes into close contact with the first on the ...

Mayo Genomic Discovery: Protecting Kidney Function During Heart Failure

... Clinic cardiology researchers have found a peptide that helps preserve and improve kidney function ... blood pressure. Earlier variations of this peptide caused blood pressure to drop limiting the ... and keep you out of the hospital." This new peptide (a unique link of amino acids) has been tested in ...

Amylin Pharmaceuticals to Present Compelling Efficacy and Safety Data From Diabetes Programs at ADA 2009

... symposia focused on the potential of peptide therapy treatment approaches for type 2 diabetes, ... SYMPOSIA "Effective Use of peptide Therapies for Optimal Glucose and Weight Control ... healthcare providers understand the potential of peptide therapy treatment approaches for diabetes. The ...

Study reveals current multi-component vaccines may need reworking

... when exposed to high enough levels of the peptide representing it. Andrea Sant, Ph.D., ... the quality that confers immunodominance on a peptide to be the strength and lifespan (kinetic ... pockets on the MHC class II molecule for a given peptide to fit into it before the complex heads to the ...

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Peptide in Medical Technology

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

... first candidate from the Company's Cationic Lytic peptide (CLYP(TM)) platform technology. EP-100 is a targeted membrane-disrupting peptide and is designed to selectively target luteinizing ... poster presentation entitled, "Targeted Oncolytic peptide for Treatment of Ovarian Cancers" at the American ...

FDA Submission of B-R-A-H-M-S MR-proANP Kryptor

... Kryptor Test. Atrial Natriuretic peptide (ANP) is predominantly produced in the atrium of ... and cardiovascular homeostasis. Although this peptide is unstable, the B-R-A-H-M-S-assay detects the ... fragment: the Mid-Regional pro-Atrial Natriuretic peptide (MR-proANP). In contrast to the mature peptide, ...

Amylin Pharmaceuticals to Present Novel Data on Promising Obesity Pipeline at 2008 Annual Scientific Meeting of The Obesity Society

... and weight-lowering actions of AC164209, a peptide hybrid linking a glucagon-like peptide-1 (GLP-1) ... 8. Corporate-sponsored symposium: "Emerging peptide Hormone Therapies for the Treatment of ... help healthcare providers understand the peptide hormone approach to the treatment of ....

Palatin Technologies Presents PL-3994 Clinical Trial Results at the 12th Annual Scientific Meeting of the Heart Failure Association of America

... to the development of proprietary peptide, peptide mimetic and small molecule compounds with a focus on melanocortin and natriuretic peptide receptor systems. The melanocortin system is ... inflammation-related diseases. The natriuretic peptide receptor system has numerous cardiovascular ...

Peptimmune Announces Grant of United States Patent for PI-2301 Peptide Copolymer for Multiple Sclerosis

... the composition of matter for its PI-2301 peptide copolymer for the treatment of autoimmune ... the development of our intellectual property in peptide copolymers, including PI-2301," stated Thomas P. ... diseases." PI-2301 is a second-generation peptide copolymer from a similar compound class as ...

Shire to add New Orphan Drug to its HGT Portfolio - EU Launch Imminent

... bring worldwide rights to FIRAZYR (Icatibant), a peptide based therapeutic for HAE which has received a ... assets include Jerini Ophthalmic, Inc. and JPT peptide Technologies GmbH - Unanimous support from ... Age-related Macular Degeneration (AMD) and JPT peptide Technologies GmbH, ...

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Peptide in Medical Products

C6 B. burgdorferi (Lyme) ELISA Kit

Description:... This ELISA is based on the C6 peptide antigen, a 26 amino acid sequence of the surface protein VlsE. This peptide has been shown to represent the immunodominant ... protein. Recent studies have shown that the C6 peptide is a sensitive and specific marker for antibody ...
Company:Immunetics, Inc.

Uniphor electrophoresis units

Description:... UniPhor units can be used for: Analytical Protein and peptide Characterization: Denaturing and non denaturing SDS-PAGE gels IEF in ultrathin PAGE gels (Z64,072-7, Z64,071-9& Z64,075 1) Preparative Protein and peptide Separation: Non-denaturating PAGE gels and Agarose gels IEF in Agarose ...
Company:Sigma-Aldrich

PYY, Total ELISA Test

Description:... peptide YY (PYY) was first identified in 1980 (1) and has ... the N-terminal truncated form of the full length peptide (3). In common with leptin, this peptide has been shown to cross the blood-brain-barrier ...
Company:Diagnostic Systems Laboratories, Inc.

DIASTAT™ Anti-CCP

Description:... second-generation peptide-based test, DIASTAT Anti-CCP* is an ELISA based on the detection of autoantibodies against the cyclic citrullinated peptide (CCP) containing modified arginine residues in human serum or plasma. Enabling early and accurate diagnosis of RA, the Anti-CCP assay provides an ...
Company:Inverness Medical Innovations

ALS, Total ELISA Test

Description:... Acid-labile subunit (ALS) is a GH dependent protein which is produced in the liver as a 578 amino acid peptide with a predicted molecular weight of 63.3 kDa. IGFs in human serum are mostly confined to a ~150 KDa GH-dependent ternary protein complex consisting ...
Company:Diagnostic Systems Laboratories, Inc.

Ghrelin, Total ELISA Test

Description:... Ghrelin is a 28 amino-acid lipophilic peptide with a labile octanoic acid side chain at the serine residue three, that is primarily expressed in specialized enterochromaffin cells located mainly ...
Company:Diagnostic Systems Laboratories, Inc.

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Peptide in Medical Definition

Proteopathy

... Alzheimer's disease, Cerebral β-amyloid angiopathy Amyloid β peptide (Aβ) (senile plaques), Tau protein (fibers) Prion diseases ... β2-microglobulin Inclusion body myopathy/myositis Amyloid β peptide (Aβ) Cataracts Crystallins Medullary thyroid carcinoma ...

Muscle atrophy

... ubiquitin / proteasome pathway. In this system, particular proteins are targeted for destruction by the ligation of at least four copies of a small peptide called ubiquitin onto a substrate protein. When a substrate is thus "poly-ubiquitinated", it is targeted for destruction by the proteasome . ...

Thymocyte

... MHC/HLA, to ensure reactivity and specificity. [1] Positive selection selects cells with a T cell receptor able to bind MHC class I/II or peptide molecules with at least a weak affinity. This eliminates (by a process called "death by neglect") those T cells which would be non-functional due to ...
Peptide in Medical Dictionary

Tryptophan

... going to bed. N- alpha acetyltransferase; peptide neurotransmitter; peptide peptidohydrolases; peptide ...

Atria

... ... Liver function tests Serum uric acid Atria l natriuretic peptide (ANP) and brain natriuretic peptide (BNP) Urinalysis Urinary sodium Creatinine clearance Swan-Ganz ...

BUN

... Liver function tests Serum uric acid Atria l natriuretic peptide (ANP) and brain natriuretic peptide (BNP) Urinalysis Urinary sodium Creatinine clearance Swan-Ganz ...

Creatinine clearance

... ... Liver function tests Serum uric acid Atria l natriuretic peptide (ANP) and brain natriuretic peptide (BNP) Urinalysis Urinary sodium Creatinine clearance Swan-Ganz ...

Creatinine

... Liver function tests Serum uric acid Atria l natriuretic peptide (ANP) and brain natriuretic peptide (BNP) Urinalysis Urinary sodium Creatinine clearance Swan-Ganz ...

Liver function tests

... ... Liver function tests Serum uric acid Atria l natriuretic peptide (ANP) and brain natriuretic peptide (BNP) Urinalysis Urinary sodium Creatinine clearance Swan-Ganz ...

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Peptide in Biological News

Singapore nanotechnology combats fatal brain infections

... and fungal infections with novel peptide nanoparticles developed by scientists at the ... and brain damage in patients. IBN's peptide nanoparticles, on the other hand, contain a ... that require treatment. The ability of IBN's peptide nanoparticles to traverse the blood brain barrier ...

Tips from the journals of the American Society for Microbiology

... 5825-5834.) Newly Developed Antimicrobial peptide May Protect Mice from Lethal Bacterial Infections ... from Japan suggest that a synthetic antimicrobial peptide identified as L5 may prevent death in mice ... researchers developed the cationic antimicrobial peptide L5 out of antibacterial proteins from Sarcophaga ...

Alzheimer's disease therapeutic prevents long-term damage from TBI in pre-clinical studies

... designed to prevent build-up of amyloid, a toxic peptide found in the brain. This peptide clogs the brains of Alzheimer's patients but it ... the investigators sought to understand if amyloid peptide contributed to secondary injury. Amyloid peptides ...

Peptides-on-demand: McGill researcher's radical new green chemistry makes the impossible possible

... "Currently, to generate peptides you must use a peptide synthesizer, an expensive piece of high-tech ... to construct a single, simple "skeleton" peptide which can be modified into any other peptide needed with the addition of a simple reagent. ...

Common gene variants increase risk of hypertension, may lead to new therapies

... variants associated with changes in natriuretic peptide levels were then tested in the same individuals ... the heart when it is stressed, and screening for peptide levels is widely used to diagnose heart failure, ... premature to advocate screening natriuretic peptide levels or gene variants to diagnose hypertension ...

Gene therapy reversed heart damage in heart failure

... rats were treated with a gene that generates a peptide called ARKct, which was administered to ... show that beta blockers and the ARKct peptide are compatible and can be given together," Dr. ... In future trials in humans, the ARKct peptide will be administered with beta blockers, which ...

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Peptide in Biological Technology

Palatin Technologies, Inc. Receives U.S. Patent Allowance for Heart Failure Drug Candidate

... Number 11/694,260, titled "Cyclic Natriuretic peptide Constructs." Allowed claims cover a family of cyclic compounds that bind to natriuretic peptide receptor A (NPRA), including PL-3994, Palatin's ... "PL-3994 and related compounds are first-in-class peptide mimetics with extended half-lives and favorable ...

DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology

... biotechnology products derived from synthetic peptide chemistry or recombinant DNA," said Christopher ... clinical development of an oral form of the peptide hormone drug leuprolide using the LPM(TM) technology. Leuprolide is a synthetic peptide agonist of gonadotropin releasing hormone (GnRh) ...

METTLER TOLEDO Introduces an Affordable Reaction Block for Solid Phase Peptide Synthesis (SPPS)

... an affordable reaction block for solid phase peptide synthesis and purification of peptide libraries: MiniBlock. For a limited time, you can register to win a MiniBlock® for Solid Phase peptide Synthesis (SPPS). ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

... ) last week analyzed the most recent peptide genomic sequence data available and determined ... ) last week analyzed the most recent peptide genomic sequence data available and determined ... testing. It used the same approach to produce a peptide H5N1 (avian flu) vaccine that successfully ...

First H1N1 Swine Flu Vaccine, Replikins-Based, Is Ready Now for Testing Worldwide

... LONDON, May 4 /PRNewswire/ -- A synthetic peptide H1N1 vaccine is available now for testing ... developed the vaccine based on the same Replikins peptide technology which provided the surprise advance ... the company also takes full advantage of modern peptide synthesis techniques to allow rapid production of ...

Pulmo BioTech Inc. Announces Paper to be Presented at Symposium

... a paper at the 5th International Symposium on peptide Receptors and Kinin 2009 to be held in Quebec, ... Circulation", will be part of the session "From a peptide to a Drug: Rational Drug Design". This ... paper on our Molecular Imaging technology at the peptide Receptors International Symposium. As a company, ...

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Peptide in Biological Products

Phospho-peptide Antibody from Proteintech Group, Inc.

Description:... peptide Antigen Design Customer peptide Synthesis Containing one Phospho-Amino Acid ... 20 mg will be returned to customer conjugation of peptide to KLH protein Rabbits x 2, Maintenance ...
Company:Proteintech Group, Inc.

Rabbit Anti-Human COP9 signalosome complex subunit 2 Polyclonal Antibody, Unconjugated from Aviva Systems Biology

Description:... produced in rabbits immunized with a synthetic peptide corresponding to a region of Human COPS2 with an ... Quality Control: Rabbit Ig G is purified by peptide affinity chromatography method ELISA Titre Using peptide Based Assay: 1:62500 Suggested Working ...
Company:Aviva Systems Biology

Peptides from Thermo Scientific

Description:... an expertise in the forefront of chemical peptide synthesis - both for solid support synthesis and ... quality standard. Our team of expert peptide scientists will support you starting from the design phase of your peptide to the right choice of modifications. Just ...
Company:Thermo Scientific

EvoQuest Custom Peptide Services from Invitrogen

Description:... EvoQuest Custom peptide Services offer a full range of peptide synthesis options to meet your research needs. Services include: peptide synthesis, crude product (approximately 50% pure) ...
Company:Invitrogen

Custom Protein Kinase Substrate (PKS) Peptide Microarray from LC Sciences

Description:... of our comprehensive Protein Kinase Substrate - peptide Microarray Service. Custom Probe Content Probe ... kinase assays focus on a single to a few peptide or protein substrates. Profiling kinases on a peptide microarray offers the opportunity to study ...
Company:LC Sciences

Mouse resistin Neutralizing Peptide from ABR-Affinity BioReagents

Description:... PEP-165 is an 18 amino acid synthetic peptide whose sequences are derived from mouse resistin protein. The sequence of this peptide is (amino to carboxy terminus): S(21) - S - M - P ... A - I - D - K - K - I - K - Q - D - C(39). This peptide may be used for neutralization and control ...
Company:ABR-Affinity BioReagents

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Peptide in Biological Definition

Amino acid

... from the carboxylic side) in the formation of a peptide bond . Contents ... created by polymerization of amino acids by peptide bonds in a process called translation . peptide bond formation 1. Amino acid; 2, zwitterion ...

Hormone

... Examples are catecholamines and thyroxine . peptide hormones consist of chains of amino acids. Examples of small peptide hormones are TRH and vasopressin . Peptides ... (T4) triiodothyronine (T3) peptide hormones : antimullerian hormone (AMH, also ...

Neurotransmitter

... Bombesin/GRP: bombesin gastrin releasing peptide (GRP) Gastrins: gastrin ... Y (NY) pancreatic polypeptide (PP) peptide YY (PYY) Opioids : corticotropin ... motilin glucagon vasoactive intestinal peptide (VIP) growth hormone-releasing factor (GRF) ...

Peptide bond

... A peptide bond is a chemical bond formed between two ... reaction The resulting C-N bond is called a peptide bond, and the resulting molecule is called an ... are chains of amino acids held together by peptide bonds. The backbone of PNA is also held ...

Peptide

... bond , and is sometimes referred to as a peptide bond . An amide bond is somewhat shorter than a ... by virtue of their size. Traditionally, those peptide chains that are short enough to make ... be hundreds of residues long. So, in essence, a peptide is a small protein . There is considerable ...

Peptide

... bond , and is sometimes referred to as a peptide bond . An amide bond is somewhat shorter than a ... by virtue of their size. Traditionally, those peptide chains that are short enough to make ... be hundreds of residues long. So, in essence, a peptide is a small protein . There is considerable ...

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Peptide in Biological Dictionary

Signal Sequence

... for the effective secretion ... Signal peptide A signal peptide is a short (3-60 amino acids long) peptide chain ... sources refer to signal peptides ...

Peptide-binding groove

... Pockets in the peptide - binding groove of MHC molecules accommodate anchor side ... F and to hold the peptide in the binding groove , rather than a ... ... of the H-2Kb molecule, which shield the dEV8 peptide in the binding groove . ... is angled away ...

Peptides

... and the next is known as an amide bond or a peptide bond. Antimicrobial peptides are an ... science products company which deals in Custom peptide Synthesis, Services Amylin Peptides , Trojan Peptides , Oxygen peptide , ... Peptides International manufactures ...

Peptide Bond

... A peptide bond (amide bond ) is a chemical bond formed ... and the next is known as an amide bond or a peptide bond . A peptide is a chain of amino acids linked together by ...

Peptide

... and the next is known as an amide bond or a peptide bond. C- peptide is a peptide that is made when proinsulin is split into ...

N-terminus

... amine group (-NH2). The convention for writing peptide sequences is to put the N - terminus on the ... group (-COOH). The convention for writing peptide sequences is to put the C-terminal end on the ... Human IL-21 N-terminus . DATASHEET. Specificity: peptide sequence ... Above: Immunocytochemistry of ...

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