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Pathway in Medical News

Abnormal Brain Circuits May Prevent Movement Disorder

... identified two discrete areas along the pathway that links the cerebellum to the motor cortex ... saw that there were two places along the motor pathway that seemed to stop the flow of neural signals ... concluded. "We found a consistent cerebellar pathway problem in all DYT1 carriers. When we went back ...

Scientists Track Impact of DNA Damage in the Developing Brain

... the first time researchers have switched off a pathway for repairing damaged single DNA strands in an ... long recognized as the master regulator of a pathway essential for single-strand DNA repair in the ... McKinnon said, loss of Xrcc1 activated the p53 pathway and blocked the cells from completing the cell ...

Critical link in cell death pathway revealed

... (the cells that produce insulin), that direct pathway is not sufficient to kill the cells; amplification of the apoptosis signalling pathway is required." Professor Strasser, with Drs ... thereby interfering with the normal cell death pathway for liver cells and increasing the likelihood of ...

GetWellNetwork Introduces Discharge Planning Tools in Latest Version of PatientLife System

... including our own; the 'Countdown to Discharge' pathway will enhance our ability to establish and ... include: "Countdown to Discharge" pathway -- Designed to engage patients in the discharge ... to discharge, the "Countdown to Discharge" pathway delivers timely information about this important ...

Ben-Gurion U. researchers identify how stressed fat tissue malfunctions

... of Leipzig, Germany, have identified a signaling pathway that is operational in intra-abdominal fat, the ... surgery. The team identified a signaling pathway that is operational in intra-abdominal fat, the ... The degree of activation of a signaling pathway from these individuals was compared with those of ...

Cell Pathway May Be Key to Lung Cancer's Spread

... Cancer Center are focusing on the same cellular pathway that causes colorectal cancer to develop and ... know that an abnormal, over-stimulated WNT/TCF pathway can trigger the development of colorectal cancer. ... They found that the WNT/TCF cell-signaling pathway was the only one of six pathways tested that was ...

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Pathway in Medical Technology

VisEn Molecular Imaging Technology Enables Key Insights Into Newly Discovered Biologic Pathway Published in SCIENCE

... have discovered a key disease-related biologic pathway using an integrated and innovative array of in ... technologies. The newly reported biologic pathway relates to monocyte deployment from the spleen to ... scientists discovered and detailed the biologic pathway through the use of a series of advanced and ...

Semafore's SF1126, a Vascular Targeted Pan-PI3K/mTOR Inhibitor, Is Well Tolerated and Demonstrates Activity in Phase I Solid Tumor Patients

... types are associated with aberrations of the PI3K pathway that commonly lead to resistance and poor ... of tumor tissue confirmed inhibition of the PI3K pathway by complete absence of a downstream target (pS6). ... cascades can lead to cancer and aberrant PI3K pathway activity is observed with high frequency in a ...

Mayo Researchers Help Discover Genetic Cause for Primary Biliary Cirrhosis

... biliary cirrhosis. These two genes constitute a pathway of the immune system. Potential therapeutic manipulation of this pathway provides new possibilities for more effective ... "Although both the HLA region and the IL12 pathway are equally involved with susceptibility to ...

FDA Accepts Arno Therapeutics' IND for AR-12 a PDK1 Inhibitor That Blocks the PI3K/Akt Pathway

... PDK1 inhibitor that blocks the PI3K/Akt pathway and induces the endoplasmic reticulum stress ... PDK1 inhibitor that blocks the PI3K/Akt pathway and induces the endoplasmic reticulum stress ... available PDK1 inhibitor that blocks the PI3K/Akt pathway and induces the endoplasmic reticulum stress ...

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

... complex inhibitor of the PI3K/Akt/mTOR pathway showing efficacy in retinal scarring caused by ... "Palomid 529, An Inhibitor of the Akt/mTOR pathway Reduces Photoreceptor Cell Death Following ... inhibiting the PI3K/Akt/mTor signal transduction pathway by Palomid 529 may be neuroprotective to ...

Semafore Achieves a Preclinical Milestone with SF2626, a PI3K-MEK Dual Pathway Kinase Inhibitor

... of both the PI3K (Phosphoinositide-3-kinase) pathway and the Ras-MAPK (Ras-mitogen activated protein ... both pathways in treating cancer. Both the PI3K pathway and the Ras-MAPK pathways have emerged as central ... scientific studies demonstrate that the Ras-MAPK pathway has the ability to cross-talk to the ...

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Pathway in Medical Products

TotalCare® Bariatric Bed

Description:... can easily and frequently position immobile patients per physician and nursing "up-in-chair" orders earlier, throughout the patient's clinical pathway with the simple touch of a button. FullChair® Chair Egress Position Mechanism This simple mechanism facilitates foot-of-bed or side egress ...
Company:Hill-Rom Services, Inc.

AL2500 AirLife™ Prefilled Humidifier Systems

Description:... feature a dual-purpose reservoir with a snap-open trigger, which makes a round opening for secure attachment of a humidifier adapter. The oxygen pathway is designed to help prevent particulate from reaching oxygen delivery tubing. An audible relief valve warns if the patient`s tubing becomes ...
Company:Cardinal Health, Inc.

Prometheus Pathway CTS 2000 Evaluation and Training System

Description:... Help restore pelvic muscle function with the Prometheus pathway CTS 2000 evaluation and training ....
Company:Medtronic Urology/Urogynecology

Endotrol® Tracheal Tube with Controllable Tip

Description:... tracheal tube with directional distal tip control for fast, easy intubation. Indications For Usage: Emergency situations When the intubating pathway is abnormal. Blind nasal intubations. ...
Company:Nellcor

Epidural Spinal Electrodes

Description:... Ad-Techs Spinal Electrodes are intended for intraoperative monitoring of Evoked Potentials (EPs) of the descending pathway during spinal surgery. They are offered with 2 or 3 platinum ....
Company:Ad-Tech Medical

Wiseguide Guide Catheter

Description:... Boston Scientific Guide Catheters are intended for use in general intravascular and coronary applications. They provide a pathway through which medical instruments such as balloon dilatation catheters, guide wires or other therapeutic devices may be introduced. These devices are ...
Company:Boston Scientific Corporation

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Pathway in Medical Definition

Muscle atrophy

... of protein breakdown pathways. The particular protein degradation pathway which seems to be responsible for much of the muscle loss seen in a muscle ... by the proteasome . Particular enzymes in the ubiquitin/proteasome pathway allow ubiquitination to be directed to some proteins but not others - ...
Pathway in Medical Dictionary

Addiction

... the Zyban Advantage Plan, a personalized smoking cessation support program. The drug treats the biochemical addiction by affecting the neural pathway mechanisms felt to contribute to nicotine addiction . For all alcoholics, therapy is essential. But it's not always enough. For these patients, ...

Anesthesia

... anesthesia is used, the woman receives anesthetic medication through an IV. Anesthetic / Anesthesia : Medication injected along a nerve pathway to deaden pain . Reaction to anesthesia Excessive loss of blood Infection Additional risks specific to this surgery include the ...

Anesthetic

... this technique, medication is injected into the space around the spinal nerve s. Anesthetic / Anesthesia : Medication injected along a nerve pathway to deaden pain . Anesthetic ... By Medieval Monks - Source:MedicineNet Dental : Easing Children's Fears of the Dentist - Source:WebMD ...

Beta

... Local beta radiation is delivered to the site to inhibit re stenosis . Mfg: Novoste Corporation. The Wnt/ beta -catenin signal transduction pathway plays a critical role in axis formation and head versus trunk induction during early vertebrate embryogenesis. - A lack of beta -carotene (pro- ...

Carcinogen

... The Biology of Carcinogen esis Understanding the biology of carcinogen esis is crucial to the development of effective chemo prevention . This pathway also plays a pivotal role in human carcinogen esis, because several key Wnt signaling components are encoded by human onco genes or tumor ...

Cone

... Answer: Absolutely, you should worry. Axon guidance molecules are molecules outside the growth cone that assist in selection of the correct pathway and target by changing growth direction. Keratoconus is a condition in which the cornea thins and becomes cone shaped. It usually occurs ...

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Pathway in Biological News

Abnormal brain circuits may prevent movement disorder

... identified two discrete areas along the pathway that links the cerebellum to the motor cortex ... saw that there were two places along the motor pathway that seemed to stop the flow of neural signals ... concluded. "We found a consistent cerebellar pathway problem in all DYT1 carriers. When we went back ...

Study reveals a reprogrammed role for the androgen receptor

... the androgen receptor directs a distinct gene pathway in androgen-independent prostate cancers may lead to the identification of genes in that pathway that can be targeted by future ... active. The genes form a completely separate pathway from the one active in androgen-dependent ...

Scientists track impact of DNA damage in the developing brain

... the first time researchers have switched off a pathway for repairing damaged single DNA strands in an ... long recognized as the master regulator of a pathway essential for single-strand DNA repair in the ... McKinnon said, loss of Xrcc1 activated the p53 pathway and blocked the cells from completing the cell ...

Grant supports LSUHSC research on how like cell receptor systems determine very different functions

... are interested in how the generic ERK signaling pathway confers specific physiological outcomes such as ... 'scaffolding' molecules that assemble the pathway around growth factor receptors." The ... provide insight into how specific functions of a pathway might be targeted therapeutically while not ...

UCLA researchers discover new molecular pathway for targeting cancer, disease

... has identified a way to turn off a key signaling pathway involved in physiological processes that can also ... in an unregulated manner, however, the Hh pathway can also cause cancers of the brain, lung, blood, ... Blocking such unregulated stimulation of the Hh pathway had previously been shown in animal studies to ...

Building memories with actin

... had no effect. That doesn't mean the Rac-PAK pathway isn't involved in LTP, however. The team ... their effects at different points. The Rho-ROCK pathway initiates the cytoskeletal changes of LTP, and the Rac-PAK pathway solidifies them so that heightened synapse ...

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Pathway in Biological Technology

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

... demonstrated that blocking a key cancer stem cell pathway impacts tumor cell proliferation, growth and ... antibody optimized to block a key signaling pathway in cancer stem cells. Specifically, OMP-21M18 ... an activator of Notch signaling, which is a pathway known to be important in stem cells and cancer. ...

GeneGo Donates Proprietary Cytokine Pathway Maps to ISICR

... that they have recently donated 41 canonical pathway maps to the International Society for Interferon ... experimentally validated biological and chemical pathway interactions. Each map describes multi-step ... and chemotaxis. In addition to creating canonical pathway maps GeneGo's software analysis tools enable ...

deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis

... This offers a potentially attractive new pathway for drug discovery, and the next task is to build ... SNP increases risk of these diseases and how this pathway could be targeted therapeutically to address this ... and DG031, compounds targeting the leukotriene pathway for the prevention of heart attack; and DG071 and ...

Oncothyreon's PX-866 is effective in preclinical model of pulmonary fibrosis

... metabolism. "PI-3 kinase is part of a signaling pathway that is believed to play an important role in a ... in mice mimics these diseases by activating this pathway in the lungs with a growth factor called ... suggest that inhibition of the PI-3 kinase pathway might be beneficial in such human lung diseases ...

Cardiff University Becomes a GeneGo Center of Excellence

... software and databases for systems biology and pathway analysis , today announced that the University of ... partner relationship with GeneGo to provide a pathway analysis environment for all the university's ... biology technology such as compound based pathway analysis , cheminformatics & ...

Keryx Biopharmaceuticals Presents Encouraging Preclinical Data at Annual Meeting of the American Association of Cancer Research

... the data suggests that the PI3-K/Akt/ B-catenin pathway plays an important role in mammary stem cell ... stem cells through inhibition of this signaling pathway represents a rational therapeutic strategy. ... by Cirstea et al. that dual inhibition of the Akt pathway by rapamycin (ABI-009) and Perifosine induces ...

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Pathway in Biological Products

BD Pathway 415 bioimager from BD Biosciences - Bioimaging

Description:... For applications not requiring confocal, the BD pathway 415 is a cost effective alternative to the pathway 435. And, the pathway 415 can be field-upgraded to confocal if later ...
Company:BD Biosciences - Bioimaging

BD Pathway 435 confocal bioimager from BD Biosciences - Bioimaging

Description:... The BD pathway 435 is an affordable, compact benchtop imager ... new tools and wizard-style applications, the BD pathway 435 confocal bioimager simplifies the process of ... and 3-dimensional cellular exploration. The BD pathway 435 is ideal for researchers that need ...
Company:BD Biosciences - Bioimaging

Rabbit Anti-Human PHAS-II Polyclonal Antibody, Unconjugated from Lab Vision

Description:... Pharmacological and genetic evidence indicates that the mTOR/p70S6K pathway is involved in the control of PHAS-I and -II. Thus, PHAS proteins may be mediators of the effects of this pathway on protein synthesis and cell proliferation. Antigen: A synthetic ...
Company:Lab Vision

Ubiquitin Fraction I Extract from GeneTex

Description:... transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The ...
Company:GeneTex

IRS Extract from GeneTex

Description:... transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The ...
Company:GeneTex

26S Proteasome Fraction Extract from GeneTex

Description:... transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The ...
Company:GeneTex

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Pathway in Biological Definition

Apoptosis

... of TNF to TNF-R1 has been shown to fire-off the pathway that leads to activating the caspases [9] . ... on biochemical execution). The apoptotic pathway was found to be dramatically restored in H460 ... transformation. This apoptosis-dependent pathway for T cell activation is not present during ...

Citric acid cycle

... organisms , the citric acid cycle is a metabolic pathway that forms part of the break down of ... who proposed the key elements of this pathway in 1937 and was awarded the Nobel Prize in ... citric acid cycle is called an amphibolic pathway because it participates in both catabolism and ...

Enzyme

... identical, independent of the specific individual pathway taken from beginning point to end point. This is ... by the possibility of a cycle of moving down a pathway releasing less net energy and back up a different pathway with higher net energy, or vice versa. An enzyme ...

Glycolysis

... Glycolysis is the initial metabolic pathway of carbohydrate catabolism . The most common ... pathways, such as the Entner-Doudoroff pathway . However, glycolysis will be used here as a synonym for the Embden-Meyerhof pathway . Glycolysis is the most universal process by ...

Citric acid cycle

... organisms , the citric acid cycle is a metabolic pathway that forms part of the break down of ... who proposed the key elements of this pathway in 1937 and was awarded the Nobel Prize in ... citric acid cycle is called an amphibolic pathway because it participates in both catabolism and ...

Long-term potentiation

... LH, Lisman JE (2000) "Inhibition of the cAMP pathway decreases early long-term potentiation at CA1 ... LH, Lisman JE (2000) "Inhibition of the cAMP pathway decreases early long-term potentiation at CA1 ... in the Schaffer collateral-commissural pathway of the rat hippocampus." J Physiol. 1983 ...

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Pathway in Biological Dictionary

Reflex arc

... A reflex arc is the neural pathway that mediates a reflex action. In higher ... to ... A reflex arc refers to the neural pathway that a nerve impulse follows. ... It is the ... by a ... A reflex arc is the neural pathway that mediates a reflex action. ... When a ...

Glycolysis

... Glycolysis is the metabolic pathway that converts glucose, C6H12O6, into pyruvate, ... of cells. Glucose enters the Glycolysis pathway by conversion to glucose-6-phosphate. ... Glycolysis is a biochemical pathway by which a molecule of glucose (Glc) is ... ...

Citric acid cycle

... the citric acid cycle is a metabolic pathway that forms ... The citric acid cycle also ... of animals and certain other species, the major pathway for the complete oxidation of acetyl coenzyme ... The citric acid cycle is the final common pathway for the oxidation of fuel ... This is the ...

Transmembrane receptor

... transmembrane receptor protein serine/threonine kinase signalling pathway ... as a consequence of a transmembrane receptor serine/threonine ... : transmembrane receptor protein tyrosine kinase signaling pathway ... 3.1.2 Signal transduction of transmembrane receptors by ...

Spinal cord

... Definition Spinal cord injury The spinal cord is the main pathway for information connecting the brain and ... The nerve fibers enter the ... cord . ... Because the spinal cord acts as the main information pathway between ... what is Spinal Cord Injury? ... What is the spinal ...

Mismatch repair

... by very ... Methyl-directed mismatch repair (MMR) is the primary pathway for correcting ... The complete mismatch repair pathway has been reconstituted in vitro (24) and ... : Genetic variations in ...

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Other Contents
(Date:8/28/2014)... Now in its 4th year, Step for Hope ... two brain aneurysm survivors. The ongoing mission of Step for ... help increase early detection and to help support individuals and ... hope that you will be able to join this remarkable ... Step for Hope Run/ Walk on Saturday, September 6, 2014. ...
(Date:8/28/2014)... FL (PRWEB) August 28, 2014 The ... that produces deep, resonant, meditative sounds that can be ... talent is needed to use it – just taking ... always sounds soothing. , Here are some examples ... ,     Close your eyes, relax, and maintain good ...
(Date:8/28/2014)... 2014 On September 1st, the National ... campaign. The goal is to help families and ... and effectively and without exposures to risky pesticides. ... “Children’s exposures to pesticides should be limited as ... Head lice are often trivialized in the media, which ...
(Date:8/27/2014)... 2014 Author and orthopedic surgeon William ... on the thrilling adventures of sharp and witty ... is gearing up for a new marketing push in ... novellas , “Prescription: Murder” follows the adventures of ... dodging assassination attempts and thwarting criminals. In the first ...
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Breaking Medicine News(10 mins):Health News:Step for Hope and Raise Brain Aneurysm Awareness 2Health News:Ever Thought of Meditating With a Harmonica; Harmonica Techs, Inventors of the Pulmonica® Pulmonary Harmonica®, Present Tips on How to Relax with Soothing Sounds 2Health News:Head Lice Can Be a Public Health Opportunity 2Health News:Head Lice Can Be a Public Health Opportunity 3Health News:Head Lice Can Be a Public Health Opportunity 4Health News:William H. Simon Launches New Marketing Campaign for Book 2Health News:Spine Guide Offering New Overview of Surgical Options For Back Pain 2
(Date:8/27/2014)... NY (June, 2014) Outstanding basic research, a ... a dedication to patient care have earned the ... University Medical Center (CUMC) and NewYork-Presbyterian Hospital an ... the National Cancer Institute (NCI). The grant renews ... NCI-designated Comprehensive Cancer Centers in New York City ...
(Date:8/27/2014)... associated with outcomes after the repair of peripheral ... mechanism of injury, nerve injured, injury location, defect ... repair materials. However, despite numerous studies of outcomes ... is no agreement regarding the independent predictors of ... the predictors has not been quantified. A study ...
(Date:8/27/2014)... Warwick research finds , Gamblers show the same ... research has shown. , Researchers, led by Dr Elliot ... conducted tests that found that both human gamblers and ... than low-value rewards. , Published in Biology Letters ... the important role that memories of previous biggest wins ...
Breaking Biology News(10 mins):Herbert Irving Comprehensive Cancer Center awarded $18 million grant 2Herbert Irving Comprehensive Cancer Center awarded $18 million grant 3Herbert Irving Comprehensive Cancer Center awarded $18 million grant 4Gamblers are greedy bird-brains, University of Warwick research finds 2
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