First 'atlas' of key brain genes could speed research on cancer, neurological diseases
... on specific TF genesregulating nerves involved in pain sensation, certain brain tumors, andspeech problem...development of theneurons that generate the severe pain that is a common symptom ofmetastatic tumors.The research was funded by the Charles Dana Foundation,...UCLA scientists transform HIV into cancer-seeking missile
...fur. The method is non-invasive and does not cause pain or harm to the animal. Though excited at proving that HIV can be used to target cancer cells, Chen emphasizes that the carrier must be further enhanced for safety and specificity before it can be tested as a gene-therapy method in humans. "Our next......s enrolled in the study will be examined for chest pain at one month, three months and six months. A total of 404 patients will be enrolled in the study at the 20 study sites across the country. The Genetic Angiogenic Stimulation Investigational Study (GENASIS) is funded by Corautus Genetics. More than ...Potential treatments for neurofibromatosis
... miserable and debilitated with chronic itching or pain from disfiguring tumors. Infants affected by the disease face possible paralysis or damage to the brain and other organs. The disease frustrates doctors because there's no effective treatment even though the responsible gene was identified more than...PET/MRI scans may help unravel mechanisms of prenatal drug damage
...logists are relying on the mother transferring the pain medication to the fetus via the placenta. But we a...now if what we give is sufficient to 'satisfy' the pain level of the fetus," said Benveniste, who is also a professor of anesthesiology at Stony Brook Unive...Screening of Corticosteroids in Urine by Negative Atmospheric Pressure Chemical Ionization LC/MS/MS
...nts [2,3]. Moreover, corticosteroids can alleviate pain in general. To prevent their misuse related to euphoria and pain suppression, the anti-doping governing bodies are restricting the use of corticosteroids. Systemic u...... to treatment, they may be spared the unnecessary pain associated with combination regimens. One potential way to do this is through employment of pharmacogenomics. The first step in a potential strategy would be to categorize patients based on the molecular profile of their tumor. This can ...Visions: IT exec says CIOs must be ready to help companies ramp up trade
...es jobs here. In 20 years, Iyer has witnessed the pain and the positive changes increased trade has brought. He said one point that gets lost in the concern about job losses is that by helping India and China build their economies, work is created here. He has walked the streets of Bangalore and seen eq...Barriers will not stop convergence of medical technologies
...medical therapies. Some conditions - such as back pain - can have either surgical or medical treatment options in which it is not definitively clear which approach is necessarily better. This concept was addressed in my column earlier this year reporting on the pivotal spine patient outcomes research ...What patients want: A story of choice, clinical trials & evidence-based medicine
...es. Indeed, it seems there as many cures for back pain as there are people with back pain. For anybody wi...c conclusion was that discectomy relieved the back pain more quickly but that most people eventually improved in equal fashion and that conservative waiting...New Drug in Diabetic Neuropathy
...nful condition which is a very agonizing nighttime pain seen in diabetics. However, new hope lies with exp...ocks NMDA receptors, which are believed to mediate pain effects in diabetic neuropathy being researched by Central Arkansas Research, Arkansas. This drug sh...Fibroids unlikely to Turn Cancerous
...hs in the uterus which sometimes cause discomfort, pain and bleeding. According to Dr. Kevin Reynolds, chief of gynecologic oncology at the University of Michigan Comprehensive Cancer Center, in Ann Arbor, removal of fibroids is the largest single reason hysterectomies are performed in the United States. ...Painkillers Do Not Shorten Dying Patients' Lives
...f the study."This study dispels the myth that good pain control at the end of life means killing the patie...t. People should not fear that taking morphine for pain need shorten life, and any doctor with such a worry about one of their patients should seek speciali...Serum Progesterone Helps Stratify Ectopic Pregnancy Risk
...resented to an emergency department with abdominal pain or vaginal bleeding. Patients were monitored until intrauterine or ectopic pregnancy was confirmed. Follow-up showed that, altogether, 61% were viable intrauterine pregnancies, 32% were nonviable intrauterine pregnancies and 7.3% were ectopic pregnan...Pancreatitis: Minimially Invasive Procedure Offers Long-Term Pain Relief
...rn to a minimally invasive operation for long-term pain relief, according to a new study by Johns Hopkins ...dominal and back pain. In many cases, Kalloo says, pain may be caused by elevated pressures in the pancreatic duct. For these patients, endoscopic therapy t...Neer II* Total Shoulder System
...ater than 50%, head-splitting fractures, disabling pain unresponsive to conservative treatment due to oste...deal for total shoulder arthoplasty. Indicated for pain due to incongruity of both the glenoid and humeral head, with intact or repairable rotator cuff.......r is a complete system for stereotactic lesioning, pain treatment, stimulation and bipolar coagulation. It features a radio frequency (RF) energy source with sophisticated, integrated monitoring and control features....... restored range of motion coupled with significant pain reduction. Extended clinical follow-up of implants has validated the efficacy of the system's truly unique design; combining an intercarpal fusion with the arthroplasty, and utilizing two peripheral screws for carpal component fixation.. Complication......ate is intended for use in patients suffering from pain and/or loss of function due to SLAC and SNAC wrist, post-traumatic arthritis, fractures, carpal instability or rheumatoid arthritis. When combined with the specially designed screws included in the system, the plate acts as a compression device, prov...Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
...rotocols for diagnosing ACS in patients with chest pain necessitates the reduction of turnaround time (TAT) for cardiac marker results. Recommendations for the optimum TAT vary from 30 to 60 minutes. With regard to TAT, quantitative point of care (POC) assays that directly assay whole blood provide an a...Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
...t (N=103) were acneform rash(76%), asthenia (45%), pain (28%), fever (27%) and weight loss(27%). The most common adverse events seen in patients with mCRCreceiving ERBITUX with irinotecan (n=354) or ERBITUX as a singleagent (n=420) were acneform rash (88%/90%), asthenia/malaise(73%/48%), diarrhea (72%/25......aused a statistically significant reduction in the pain anditching of a rash that results from the use of ...neck, back, hands, and/or legs resulting in severe pain and itchingfor the patient. We know of no other evidence-based topicalapplications reported in the s......complete remission ofactinic lesions. Since strong pain often occurs during photodynamictherapy with competitor products, the appearance of pain during theirradiation after BF-200 ALA application was also monitored. When patients were evaluat......fter completion of surgery when patients reporteda pain intensity score (PI) of at least 2 (moderate pain)...dminister AeroLEF(TM) to treat up to twoadditional pain episodes during the study period. For each painepisode, patients were instructed to continue theself...