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Oxidation in Medical News

New study shows how spikes in nitrite can have

... a lasting impact on the heart by modulating its oxidation status and its protein machinery. Nitrite, an oxidation product of the ubiquitous short-lived cell ... are continuously produced from nitrate, another oxidation product of NO and a constituent of green, leafy ...

Penn study demonstrates new way to boost immune memory

... findings, CD8 T cells lacking TRAF6 display defective fatty acid oxidation in response to growth factor withdrawal. Giving the mutant mice the metformin restored fatty acid oxidation and the generation of memory cells that lack TRAF6. Remarkably, this ...

Oxidized LDL Cholesterol Linked to Metabolic Syndrome

... News) -- Higher levels of LDL cholesterol "packets" that have undergone oxidation are associated with an increased risk of developing metabolic syndrome, a ... The thought is that what is happening in atherosclerosis is that minimal oxidation initiates damage to the artery wall." What gets oxidized is not the ...

New Study: Pycnogenol(R) Improves Memory in Elderly

... Pycnogenol(R), but not in the placebo group. F2-isoprostanes develop by oxidation of unsaturated fatty acids, which are present in particularly high ... of Pycnogenol(R) significantly improving memory after three months and the oxidation of nerve membranes being significantly inhibited suggests that the ...

EPA grant to UC engineering makes for a better environment

... with large concentrations of microcystin-LR. The team used a chemical oxidation system that was very effective in destroying the toxin. UCs program is ... projects in Dionysious group, also deals with mechanistic aspects of oxidation of toxins in water using different powerful oxidizing reactive species, ...

Earth's Oxygen May Have Arrived Earlier

... oxygen levels increased sharply from very low levels during the Great oxidation Event, which occurred between 2.3 billion and 2.4 billion years ago. There ... years ago. "We seem to have captured a piece of time before the Great oxidation Event during which the amount of oxygen was actually changing -- caught in ...

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Oxidation in Medical Technology

Heart Disease Treatment Breakthrough

... molecule. The early studies have shown that Ateronon can inhibit the oxidation of low density lipoprotein (LDL) cholesterol, which can put people at risk ... , in the expectation that they will demonstrate that the reduction of LDL oxidation is translated into improved heart and circulatory health - and improved ...

Data Confirm Synvista Therapeutics Haptoglobin Diagnostic Test Kit Success in Rapidly Determining Cardiovascular Risk in Patients with Diabetes

... (36%) and Hp1-2 (48%) For a variety of reasons, well described in the literature, Hp2-2 is more effective than Hp1-1 at preventing hemoglobin-induced oxidation in the bloodstream and blood vessel wall. As a result, scientists have determined that the rate of heart disease is five times higher in Hp2-2 ...

Clinical Trial Shows Cardiovascular Benefits of Rooibos, Popular Antioxidant Herbal Tea from South Africa

... by the approximate 21% decrease in conjugated dienes in the blood. Conjugated dienes are products formed in large numbers during the early stages of oxidation (destruction) of important cellular components such as fats (lipids). These lipid peroxidation products may be implicated in the development of ...

Blueberry-Supplemented Diet Shows Promise in Lowering Cholesterol in Animal Trials

... -- particularly the flavonoids. (Prior, R.L. et al J Agric Food Chem. 1998, 46: 2686-93). "Flavonoids may act as antioxidants to inhibit LDL oxidation and thereby protect against vascular insult by oxidation," says Kalt. "Flavonoids may also reduce vascular inflammation related to atherosclerosis." ...

Synvista Collaboration Demonstrates in Preclinical Studies the Mechanism for Defective Cholesterol Transport in Patients with Diabetes

... reverse cholesterol transport in DM, which can be reversed by antioxidants such as vitamin E. He proposes that strategies targeted to decrease oxidation of HDL in Hp2-2 patients may improve HDL function. Synvista has completed enrolling two cohorts of a three cohort Phase 2 clinical trial, evaluating ...

ACC Presentation Indicates Interleukin-1 Gene Variants Determine Increased Risk for Coronary Artery Disease from Oxidized Phospholipids

... of cardiovascular disease. These new data suggest a novel and clinically relevant biological link between pro-inflammatory IL-1 genotypes, oxidation of phospholipids and predisposition to CAD in younger individuals," said Sotirios Tsimikas, M.D., Associate Professor of Clinical Medicine ...
Oxidation in Medical Products

Hemaprompt Fecal Occult Blood Test

Description:... The use of guaiac as a test for the presence of blood is based on the oxidation of phenolic compounds present in guaiac to quinones, resulting in the ... the release of oxygen from hydrogen peroxide which in turn causes the oxidation of guaiac. HemaPrompt is a version of the laboratory guaiac slide test for ...
Company:Aerscher Diagnostics

Deltatrac II Metabolic Monitor

Description:... assess energy requirements and response to nutrition of patients requiring prolonged critical care. It measures caloric needs and estimates substrate oxidation of patients by continuously monitoring O2 consumption and CO2 production. The Deltatrac II also helps you to solve clinical problems related to ...
Company:Datex-Ohmeda, Inc.

Hemaprompt FG Gastric and Fecal Occult Blood Test

Description:... The use of guaiac as a test for the presence of blood is based on the oxidation of phenolic compounds present in guaiac to quinones, resulting in the production of a blue color. If blood is present, the heme portion of the ...
Company:Aerscher Diagnostics

Agility Total Ankle System

Features:... facilitates insertion and reduction Six sizes provide a superior fit for a variety of patients Gas plasma sterilization addresses poly insert oxidation and degradation issues Revision capabilities ...
Company:DePuy Orthopaedics, Inc.

Ispan SF6 Intraocular Gases

Features:... and, is administered by injection into the vitreous cavity. It is packaged in aluminum lecture bottles, which ensure no change in gas contents due to oxidation or particulate contamination. Regulator is required for dispensing and compatible with all three cylinders. It is a spill or ....
Company:Alcon Laboratories

Ispan C3F8 Intraocular Gases

Features:... and is administered by injection into the vitreous cavity. I t is packaged in aluminum lecture bottles, which ensure no change in gas contents due to oxidation or particulate contamination. Regulator is required for dispensing and compatible with all three cylinders. It is a spill or ....
Company:Alcon Laboratories
Oxidation in Medical Dictionary

Metabolite

... the amino acid tryptophan is not properly metabolize d, resulting in oxidation of its metabolite s. Vitamin C prevents that oxidation process, and thus blocks cancer development. Paraneoplastic Syndrome ...

Blackhead

... s are small, tallow-like plugs formed in the pores by the accumulation of dirt, oil, and bacteria . They are black, at the exposed end, because of oxidation rather than the presence of germs. blackhead s whitehead s pus -filled lesion s that may be painful nodules (solid, raised bumps) ... ...

Blackheads

... are small, tallow-like plugs formed in the pores by the accumulation of dirt, oil, and bacteria . They are black, at the exposed end, because of oxidation rather than the presence of germs. blackheads whitehead s pus -filled lesion s that may be painful nodules (solid, raised bumps) ... ...

Carotene

... to excessive beta carotene in the diet . The offending substance, beta carotene , is an antioxidant (a substance that protects cells against oxidation damage) and is converted by the body to vitamin A . Carotene Normal Values : The normal range is 60 to 200 mcg/dl (micrograms per deciliter). ...
Oxidation in Biological News

Landfill cover soil methane oxidation underestimated

... during waste degradation. Microbial methane oxidation reduces the emissions of methane and other ... reacting it with oxygen. A value of 0 to 10% oxidation has been recommended by the Intergovernmental ... a default value for landfill cover CH4 oxidation of 10% due to the uncertainty involved and the ...

For insulin sensitive overweight patients, 1 session of exercise improves metabolic health

... found that: the body's fat-burning oxidation rate was reduced after one day of overeating; ... each trial, researchers measured whole-body FA oxidation [FAO] and calculated non-oxidative FA disposal as ... observed that overeating suppressed fatty acid oxidation below the control levels, while exercising ...

Oxidative stress: Mechanism of cell death clarified

... The induced inactivation of GPx4 caused massive oxidation of lipids and eventually cell death. A similar ... but not by water-soluble antioxidants. Since the oxidation of fatty acids in this cell death pathway, was of ... stress is detrimental to cells by unspecific oxidation of many essential biomolecules, such as proteins ...

July 2008 GEOLOGY and GSA Today media highlights

... badlands, glacial erosion in East Greenland, oxidation of methane in southern Namibia, preservation of ... A new constraint on the antiquity of anaerobic oxidation of methane: Late Pennsylvanian seep limestones ... seeps. Birgel et al. show that the anaerobic oxidation of methane was performed by methanotrophic ...

Biosensor for measuring stress in cells

... growth and cell death. The right balance between oxidation and the reverse reaction, reduction, makes the ... possible for scientists to measure the level of oxidation and, thus, the stress status of living cells. ... The biosensor specifically measures the oxidation state of glutathione. This is an important ...

Deep sea methane scavengers captured

... microorganisms. The importance of the anaerobic oxidation of methane for the Earth's climate is known since ... all genes responsible for the anaerobic oxidation of methane, new bacterial partners of this ... a thermodynamically tricky process: the anaerobic oxidation of methane (AOM). These poorly understood ...

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Oxidation in Biological Technology

Scientists peel away the mystery behind gold's catalytic prowess

... catalyst. Haruta demonstrated the low-temperature oxidation of CO and Hutchings the hydrochlorination of ... even at temperatures as low as -76 degrees C. CO oxidation is vital to firefighters and others who must ... the active species at which the critical oxidation reaction occurs when gold is supported on iron ...

Photo-catalytic, self cleaning coating for building exteriors

... source or sunlight, TiO2 offers two unique properties: (a) strong oxidation power, and (b) super-hydrophilicity. Strong oxidation power can be used to kill bacteria attached on the wall, or oxide/remove ...

Seahorse Bioscience Receives Poster Award from the European Association for the Study of Obesity

... of Action of Metformin on Insulin Sensitization: Selective Fatty Acid oxidation (FAO) over Glucose oxidation via Inhibition of Complex I and Activation of AMP-activated protein kinase ...

New strategies against bird flu

... and lung plague. Common to all ARDS samples was the massive amount of oxidation products found within the cells. Based on these findings, the scientists ... or chemical lung pathogens trigger the oxidative stress machinery. oxidation products are intrepreted as danger-signals by the receptor TLR4. ...

Solar cell directly splits water for hydrogen

... that, combined with a dye, can mimic the electron transfer and water oxidation processes that occur in plants during photosynthesis. They reported the ... free oxygen. "Each surface iridium atom can cycle through the water oxidation reaction about 50 times per second," says Mallouk. "That is about three ...

New method may accelerate drug discovery for difficult diseases like Parkinson's

... in this line of research will be to determine precisely how the effective cyclic peptides affect Parkinson's disease cells by changing reduction or oxidation within the cell, binding to metal molecules, or perhaps another mechanism. In addition, more potent structures may be possible, so the cyclic ...

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Oxidation in Biological Products

DeStreak Reagent from GE Healthcare, formerly Amersham Biosciences

Description:... DeStreak Reagent, 1 ml. Improves reproducibility and quality of 2-D gels by preventing streaking.Eliminates extra spots caused by nonspecific oxidation of proteins.Stabilizes proteins throughout entire 2-D runs, ensuring simplified, well-resolved protein patterns.Ideal for both analytical and ...
Company:GE Healthcare, formerly Amersham Biosciences

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:... standard for the quantification of 5-OxoETE by stable isotope dilution mass spectrometry. 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the ...
Company:Cayman Chemical

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:... standard for the quantification of 5-OxoETE by stable isotope dilution mass spectrometry. 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the ...
Company:Cayman Chemical

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:... standard for the quantification of 5-OxoETE by stable isotope dilution mass spectrometry. 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the ...
Company:Cayman Chemical

Mouse Anti-Human Xanthine Oxidase / Aldehyde Oxidase Ab-2 Mouse Monoclonal Antibody, Biotin Conjugated, Clone 145.4 from Lab Vision

Description:... and xanthine to uric acid, a critical plasma antioxidant. During ischemia, XDH is reversibly converted to the oxygen radical producing XO by oxidation of essential sulfhydryl groups or irreversibly through limited proteolytic cleavage of the amino-terminus. AO has a higher affinity for aldehydes ...
Company:Lab Vision

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Oxidation in Biological Definition

Alcohol

... Dehydration 8.2.4 Esterification 8.2.5 oxidation 9 See also 10 External links ... with methanol: Alcohols can also undergo oxidation to give aldehydes , ketones or carboxylic ... p- toluenesulfonyl chloride in pyridine. oxidation Primary alcohols generally give aldehydes ...

Cellular respiration

... into energy usable for life processes. oxidation of organic material—in a bonfire, for ... rather quickly. The overall equation for the oxidation of glucose is: C 6 H 12 O 6 + 6O 2 ... + energy In cellular respiration, this oxidation process is broken down into two basic metabolic ...

Citric acid cycle

... Isocitrate 3. Isocitrate dehydrogenase oxidation NAD + NADH + H + IV. ... are broken down through a process known as beta oxidation which results in acetyl-CoA which can be used in the citric acid cycle. Sometimes beta oxidation can yield propionyl CoA which can result in ...

Enzyme

... would occur too slowly to sustain life ; oxidation of organic food compounds to provide energy, for ... in the cell by coupling its synthesis to the oxidation of sugars , which releases more energy than the ... EC 1 Oxidoreductases : catalyze oxidation /reduction reactions EC 2 Transferases : ...

Citric acid cycle

... Isocitrate 3. Isocitrate dehydrogenase oxidation NAD + NADH + H + IV. ... are broken down through a process known as beta oxidation which results in acetyl-CoA which can be used in the citric acid cycle. Sometimes beta oxidation can yield propionyl CoA which can result in ...

Redox

... for all processes in which atoms have their oxidation number (oxidation state) changed. This can be a ... by hydrogen to yield methane, or it could be the oxidation of sugar in the human body, through a series of ... uptake of an electron by a molecule or atom. oxidation describes the loss of an electron by a ...

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Oxidation in Biological Dictionary

Reducing agent

... in their chemical reactions. ... Defines oxidation and reduction in terms of oxygen, hydrogen or ... reducers. ... Oxidizing and reducing agents . oxidation in industry. Examples of ... reducing agent ... metal compounds are ... is used in the second oxidation state as an one-electron reducing agent . ... ...

Reduction

... all chemical reactions in which atoms have their oxidation number changed. This can be either a simple redox process such as the oxidation of carbon to yield carbon dioxide or the ... English dictionary and ... Today the terms oxidation and reduction are used of any reaction, not ...

Redox reaction

... ) the ... Redox Reactions & Equations oxidation Number Assignments Oxidation-Reduction ... ... Home Previous Redox Reactions & Equations oxidation Number Assignments oxidation ... Step-by-step instructions for balancing ...

Oxidation

... all chemical reactions in which atoms have their oxidation number changed. This can be either a simple redox process such as the oxidation of carbon to yield carbon dioxide or the reduction of carbon ... In chemistry, the oxidation state is an indicator of the degree of ...

FADH2

... ... of each NADH produces three ATP, while the oxidation of FADH2 produces two. ... FADH2 is the ... oxidase. Lecture Outline: ... 2 ATP's made per oxidation of FADH2 ... ... are then passed to FAD FADH2 . The Citric Acid Cycle. Circular pathway ... oxidation of NADH and FADH2 is carried out by the ...

Citric acid cycle

... species, the major pathway for the complete oxidation of acetyl coenzyme A (the Citric Acid ... cycle is the final common pathway for the oxidation of fuel ... This is the version of the ... cycle (CAC) is the final common pathway for oxidation of all ... The citric acid cycle is ...

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