Navigation Links
overload in Medical News

Ruben Studdard, American Idol Winner and R&B Pop Star, Spreads the Word about Sickle Cell Disease and the Dangers of Iron Overload

... and under-recognized condition called iron overload WHAT: The Be Sickle ... sickle cell disease (SCD) about the risk for iron overload due to blood transfusions. The event ... and Spanish) -- Free, on-site iron overload screenings (serum ferritin tests) ...

Study finds iron levels not predictive of survival for form of blood cancer

... iron), which is often used as a proxy for iron overload in the blood. "Although iron chelation ... However, there is no evidence that iron overload affects survival or morbidity." The findings ... defect. "Unfortunately, the recent focus on iron overload as a priority and not the stem cell defect is ...

Once-Daily Exjade(R) Shown to Remove Toxic Iron From the Heart and Liver, According to Data Presented at ASH

... in Sickle Cell Disease (SCD) Patients With Iron overload Showed Continued Safety and Efficacy ... in Atlanta, 8-11 December 2007.(1) Chronic iron overload is a potentially life-threatening condition ... for use in patients with transfusional iron overload who have a wide range of underlying diseases such ...

Iron overload: An important co-factor in the development of liver disease in alcoholics

... heavy drinkers with and without liver disease. A high prevalence of iron overload was found in alcoholics, which appeared to be related to the development ... 2.17 (95% CI 1.42-3.32)]. Based on these findings, it appears that iron overload is an important co-factor in the development of liver disease in ...

Exjade(R) Benefits Chronically Transfused Patients by Significantly Reducing Toxic Iron That Can Damage Key Organs, According to Landmark Trial

... the heart in beta-thalassemia patients with mild to severe cardiac iron overload -In a subgroup analysis of 341 patients with myelodysplastic ... About Exjade EXJADE is indicated for the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 ...

UCLA and biotech company develop first blood test to measure key hormone that regulates iron

... conditions affecting millions of people worldwide such as anemias and iron overload diseases. IMPACT: The new test will measure the amount of hepcidin ... leading to iron toxicity and conditions like hemochromatosis or iron overload disease. The current tests do not measure hepcidin but instead measure ...

People with Disabilities Seek Ways to Manage Higher Healthcare Costs

... prices, higher costs for food and healthcare are triggering a financial overload for families, according to http://allsup.com/Home.aspx [Allsup], which ... [Social Security Disability Insurance] benefits (SSDI). The financial overload is especially difficult for adults who have the added burden of no longer ...

BMP Sunstone Announces Official Launch of Ferriprox in PRC

... throughout Guangdong and Guangxi provinces. Ferriprox(R) treats iron overload in the bloodstream which is often associated with thalassemia, a disease ... Ferriprox has been approved in 54 countries for the treatment of iron overload in thalassemia and was the first oral iron chelator to be approved in ...

Samplify Systems Announces Next Generation Signal-Compression Technology, Prism 3.0

... feedback gain control techniques adapt the signal level too slowly to reduce dynamic range without losing signal quality for weak signals, or risking overload for strong signals. SignalTrak eschews these feedback techniques to provide optimum signal quality over a block-size of as few as four samples. ...

Madzone Marketing LLC Taps TransMedia Group to Provide Publicity Lift to Knife and Forklift(TM)

... it off," said TransMedia publicist Adrienne Mazzone. It also gets eaters to slow down so the message "I'm full" gets to the brain in time before an overload of calories. TransMedia plans to promote Knife and Forklift together with another TransMedia client, the calorie-burning beverage Celsius ...

More>>

overload in Medical Technology

MitraClip(R) Therapy Data Demonstrate Clinical Benefit in High-Risk Patients With Mitral Regurgitation

... and non-surgical patients continue to be affected by the chronic volume overload caused by MR, which requires the heart to work harder, and may ultimately ... may offer a minimally invasive alternative to reduce chronic volume overload caused by MR, while preserving traditional therapeutic options in selected ...

MitraClip(R) Therapy Data Shows Important Clinical Benefit in High Risk Patients With Functional Mitral Regurgitation at 12-Month Follow Up

... these patients undergo surgery each year. Many higher risk surgical patients and non-surgical patients continue to be affected by the chronic volume overload caused by MR, which requires the heart to work harder, and may ultimately lead to heart failure. The data were presented today by Ted Feldman, ....

First U.S. Patients Enrolled in the REALISM Continued Access Study

... United States and Europe. The vast majority of patients with significant MR are untreated, which leaves their hearts affected by the chronic volume overload caused by MR, requiring the heart to work harder, and ultimately leading to heart failure. The first patient was enrolled in REALISM by Peter ...

Two-Year Follow-Up Data Demonstrates Preservation of Adequate Mitral Valve Area in Patients Treated with the MitraClip(R) System

... and in the United States. The vast majority of patients with significant MR are untreated, which leaves their hearts affected by the chronic volume overload caused by MR, requiring the heart to work harder, and ultimately leading to heart failure. "It is important to know that the encouraging ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... Please see full Prescribing Information. About Exjade Exjade(R) (deferasirox) is indicated for the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older. Further studies are being performed to determine the ...

First European Patients Treated With the Percutaneous MitraClip(R) System

... Both in Europe and the United States, the vast majority of patients are untreated, which leaves their hearts affected by the chronic volume overload caused by MR, requiring the heart to work harder, and ultimately leading to heart failure. The first European patients were treated by the team led ...

Biopure Phase III Orthopedic Trial Results Published in Journal of Trauma

... analytical methodology used identified that the crossover patients had a greater need for an oxygen carrier, likely related to patient age, volume overload and under-treatment. The manuscript was authored by the principal investigator Jonathan S. Jahr, MD of the David Geffen School of Medicine at UCLA; ...

Pew Commission Says Industrial Scale Farm Animal Production Poses 'Unacceptable' Risks to Public Health, Environment

... that ammonia emissions from livestock contribute significantly to the eutrophication and acidification of soil and water. Some level of nutrient overload occurs naturally, but this process can be accelerated by human activities. Acidification can put stress on species diversity in the natural ...

European Medicines Agency Adopts Positive Opinion for Ranolazine for Treatment of Chronic Angina

... significant reductions in ventricular arrhythmias with ranolazine. The labeling also notes that the ability of ranolazine to reduce calcium overload is expected to improve myocardial relaxation and decrease left ventricular diastolic stiffness. The doses of the product in the EU will be 375 mg, ...

MitraClip Device Preliminary Data Suggests Improved Heart Function and Relief from Heart Failure Symptoms in Functional Mitral Regurgitation Patients

... only 20 percent, or approximately 50,000, of these patients undergo surgery each year. The other 200,000 remain affected by the chronic volume overload caused by MR, which requires the heart to work harder, ultimately leading to heart failure. Additionally, an estimated 5 million people in the U.S. ...
overload in Medical Products

Power Supply EV265 for electrophoresis, 230V

Features:... is automatically disconnected from the high voltage transformer when a ground leakage path is detected. The instrument is fully protected against any overload condition including accidental short circuit of the output. The high voltage cannot suddenly appear at the outputs. It will always increase smoothly ...
Company:Hoefer, Inc.

Power Supply EV265 for electrophoresis, 115V

Features:... is automatically disconnected from the high voltage transformer when a ground leakage path is detected. The instrument is fully protected against any overload condition including accidental short circuit of the output. The high voltage cannot suddenly appear at the outputs. It will always increase smoothly ...
Company:Hoefer, Inc.
overload in Medical Definition

Atransferrinemia

... Symptoms Severe microcytic hypochromic anemia, growth retardation and recurrent infections are the first clinical signs of the disease. Iron overload occurs mainly in the liver, heart, pancreas , thyroid , kidney and bone joints , leading to mild to severe symptoms of liver and heart ...
overload in Medical Dictionary

Iron Overload

... Iron overload is a particular risk for: People with certain ... transfusion s. Hemochromatosis ( Iron overload ) Hepatitis ( Viral Hepatitis ) Hepatitis B ... Cancer (Hepatocellular Carcinoma ) Iron overload Jaundice ... Deferasirox (Exjade) has been ...

Angioma

... ) Sporotrichosis ... Hepatic Hem angioma Hemochromatosis ( Iron overload ) Hepatitis ( Viral Hepatitis ) Hepatitis B Hepatitis B ( Sexually ... Vaccinations Liver Cancer (Hepatocellular Carcinoma ) Iron overload Jaundice ... Also called encephalotrigeminal angioma tosis, ...

Hemangioma

... and chondrosarcomas. Hepatic Hemangioma Hemochromatosis ( Iron overload ) Hepatitis ( Viral Hepatitis ) Hepatitis B Hepatitis B ( Sexually ... Vaccinations Liver Cancer (Hepatocellular Carcinoma ) Iron overload Jaundice ... Seborrheic keratoses Skin tags: Can I remove them ...

Hemochromatosis

... Bat Rabies Warning - Source:Government ... Hemochromatosis ( Iron overload ) Hepatitis ( Viral Hepatitis ) Hepatitis B Hepatitis B ( Sexually ... Vaccinations Liver Cancer (Hepatocellular Carcinoma ) Iron overload Jaundice ... Hemochromatosis , in which too much iron builds up in ...

Cirrhosis

... best ways to stop the condition getting worse. Cirrhosis Fatty Liver Gilbert Syndrome Hepatic Hemangioma Hemochromatosis ( Iron overload ) Hepatitis ( Viral Hepatitis ) Hepatitis B Hepatitis B ( Sexually Transmitted Disease s in Women) Hepatitis C Hepatitis Vaccinations ...

Congestive Heart Failure

... central sympathetic inhibition on the course of heart failure . See: SIRA and moxonidine. Sponsors: Eli Lilly and Solvay Pharmaceuticals. Fluid overload or congestive heart failure , in which fluid backs up behind the heart into the lungs , that cannot be improved enough with medications that ...

Constipation

... pain . Drowsiness , dizziness . To avoid stomach upset, take an NSAID with food . Doesn't iron cause constipation ? Certainly, iron overload may be associated with constipation . However, the vast majority of infants tolerate supplemented formulas without difficulty. How Much? How ...

Fatty liver

... Gastroesophageal reflux disease Urinary incontinence ... Fatty Liver Gilbert Syndrome Hepatic Hemangioma Hemochromatosis ( Iron overload ) Hepatitis ( Viral Hepatitis ) Hepatitis B Hepatitis B ( Sexually Transmitted Disease s in Women) Hepatitis C Hepatitis Vaccinations ...

Heart failure

... in infants under 1 year of age. Infants with the syndrome gain excessive weight during the first year of life and become obese. Fluid overload or congestive heart failure , in which fluid backs up behind the heart into the lungs , that cannot be improved enough with medications that ...

Hypercalcemia

... spread to the bone (bone metastases). gallium scan ... These include an underactive thyroid ( hypothyroidism ), a genetic disorder of iron overload ( hemochromatosis ) or excessive blood levels of calcium ( hypercalcemia ). When blood calcium levels fall ( hypocalcemia ), calcium is ...

More>>

overload in Biological News

Europe's most common genetic disease is a liver disorder

... problems. The exact origin of the genetic iron overload disorder hereditary hemochromatosis (HH) has ... damage. Hereditary hemochromatosis is an iron overload disorder that, affecting about one in 300 people, ... intestine cannot be limited as effectively and an overload develops, says Martina Muckenthaler, professor at ...

Two-pronged model could help foil tough cystic fibrosis infections

... the maximum tobramycin dosage was needed. They were also studying iron overload in CF lungs. Airway cells with the CF gene mutation release more iron, ... by the Federal Drug Administration to treat acute iron poisoning or overload can enhance the ability of tobramycin against Pseudomonas infection. ...

A genetic cause for iron deficiency

... intestine. Normally, hepcidin is produced to protect the body against iron overload but patients with IRIDA make large amounts of hepcidin even though they ... researchers say. For example, blocking TMPRSS6 may help patients with iron overload disorders make more hepcidin in order to limit intestinal iron absorption. ...

Scientists discover novel way to remove iron from ferritin

... Desferal is currently used to detoxify the blood of patients with iron overload and is a common therapeutic remedy. Ferritin is a protein that ... fatigue, weakness, joint pain and arthritis. If left untreated, iron overload can lead to serious problems, including diabetes, liver and heart disease. ...

High blood pressure, low energy -- a recipe for heart failure

... pump against high pressure. The hearts of normal mice took that pressure overload in stride and stayed healthy. Those contrasting outcomes suggest that heart health greatly depends on ERR alpha. "The stress of a cardiac pressure overload asks heart muscle to manufacture more high energy compounds, and without ...

Galloping and breathing at high speed

... digital flexor resulting from stress and strain on the tendons of the animal. According to Dr. Hermanson, "Fatigue of the deep flexor muscle may overload the superficial digital flexor muscle and tendon, especially towards the end of intense, high-speed exercise. The Importance of Respiration ...

Cutting calories could limit muscle wasting in later years

... "Such iron accumulation in muscle was quite unexpected. This may be of concern because more people are genetically predisposed to developing iron overload than we originally thought." The problem occurs when metals such as iron accumulate in the mitochondria and react with oxygen. Iron can change the ...

Avoiding Spleen Removal for Cooley's Anemia SufferersAvoiding spleen removal for Cooley's anemia suf

... patients do not require frequent transfusions. However, hemoglobin (Hb) levels often decrease over time, splenomegaly appears, and progressive iron overload occurs from increased gastrointestinal iron absorption. Despite its prevalence, Cooley's anemia (beta-thalassemia) is an orphan disease, of which ...

ASU researchers synthesize molecule with self-control

... with their molecule in the advanced online publication of Nature Nanotechnology (May 4, 2008). In nature, plants defend against this sunlight overload process using non-photochemical quenching (NPQ). This process drains off the excess light excitation energy as heat so that it cannot generate the ...

Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia

... during cardiac tachyarrhythmia.. He further stated These observations are important to the understanding of the molecular mechanisms by which calcium overload and resulting mitochondrial dysfunction and resulting oxidative stress impact atrial remodelling during atrial fibrillation. ...

More>>

overload in Biological Technology

Therapure Biopharma Inc. Announces Manufacturing Agreement with Biomedical Frontiers Incorporated -- Contract will Support Phase II Trials for Thalassemia Treatment

... build-up in the blood of patients with an iron overload disorder. Biomedical Frontiers believes that ... treatment for thalassemia and other iron overload disorders to markets." About Therapure ... iron-binding drugs for the treatment of iron overload disorders and acute iron poisoning. BMF's ...

CV Therapeutics Receives European Marketing Authorization for Ranolazine for the Treatment of Patients With Chronic Angina

... also notes that the ability of ranolazine to reduce cellular calcium overload is expected to improve myocardial relaxation and decrease left ventricular ... The labeling also notes that the ability of ranolazine to reduce calcium overload is expected to improve myocardial relaxation and decrease left ventricular ...

Cumberland Pharmaceuticals Provides Hospital In-Service Webcast for Acetadote(R)

... for those requiring fluid restriction. To avoid fluid overload, the volume of diluent should be reduced as needed. If volume is not adjusted, fluid overload can occur, potentially resulting in hyponatremia, seizure, and death. Please visit www.acetadote.net for the full prescribing information. ...

Nile Therapeutics Announces Positive Results from Phase 1b Safety and Pharmacodynamics Study of CD-NP in Patients with Heart Failure

... in stable heart failure patients. Patients with NYHA Class II or Class III heart failure, ejection fraction <40% and current signs of fluid overload were included in the study. In this dose escalation trial, four cohorts were administered a single 24-hour infusion of CD-NP at a dose of either 3 ...

BMP Sunstone Reports Second Quarter 2008 Financial Results

... will market and distribute Ferriprox under its five-year licensing agreement with Apotex, Inc. Ferriprox is a cost-effective treatment for iron overload in the bloodstream which is often associated with thalassemia, a disease that can lead to organ damage and heart failure. Thalassemia is ...

"Brave New Reality" Provides a Wide Spectrum of High Tech News and Easy Science.

... Updates by category are performed on a revolving schedule such that new content is more distributed. The intent is to avoid information overload in an area where more focus is needed to absorb the technical content. Regular visitors can spend more time reading an article and looking up ...

FDA Approves New Mechanism of Action Labeling for Ranexa(R)

... suggests that during ischemic episodes excess sodium can flow into cardiac cells through sodium channels. This excess sodium can trigger a subsequent overload of calcium that can lead to problems with proper contraction and relaxation of the heart. Late sodium current inhibition has been shown to improve ...

SLIM Search, Inc. Sponsors Next Generation Sequencing Conference for the Biomedical Market

... of short read length sequence data. He will speak about how the genomics era is maturing and how biologists are feeling the pain of the massive data overload required in modern biology. Sequence searching is a simple but fundamental process that consumes all the hardware researchers have available. He will ...

Advertising ambassador explains the reinvention of marketing

... permission to talk directly to the consumer by sending e-mails is invaluable to the company, Shereshewsky said, while cautioning marketers not to overload their customers, nor take that permission for granted by selling their lists to other companies. He noted that 35 years ago, consumers were ...

Organize the web, simply

... should consider offering on its Web site as they are relatively easy and inexpensive to deploy. And for users, it will help with the information overload you face daily. In addition to Yahoo, here are some of my favorite RSS readers: NewsGator , Feedster , Pluck , and Firefox . All of these ...

More>>

overload in Biological Dictionary

Penetrance

... alleles for colorectal cancer through a scan of 1467 ... A new US study suggests the link between a genetic mutation and the iron overload disorder haemochromatosis is more tenuous than ... Disagreement on penetrance ... Subject: SNP within DYT1 Reduces Penetrance of GAG Deletion. ...
Other Contents
(Date:4/17/2014)... targets that could be used to provide relief ... London made the discovery when researching how pain ... body. , Dr Marzia Malcangio said: "We have ... and our findings could help chemotherapy patients who ... side effect of some chemotherapy drugs (such as ...
(Date:4/17/2014)... the April issue of Experimental Biology and ... Drs. Rex Gaskins and Paul Kenis in the ... of the University of Illinois Urbana-Champaign describe their ... reactions underlie a variety of cell functions including ... these crucial roles in regulating normal cellular behavior, ...
(Date:4/17/2014)... NY In a review published in the April ... president of The Feinstein Institute for Medical Research, says ... medical community,s approach to treating sepsis, which ... Americans. , Sepsis occurs when molecules released into the ... throughout the body. Inflammation is necessary for maintaining good ...
(Date:4/17/2014)... 2014U.S. military personnel who served in Iraq and ... brain injury (TBI) were compared to military personnel ... reasons. Differences in measures of overall disability, cognitive ... injury are reported in an article in ... Mary Ann Liebert, Inc., publishers. The article is ...
(Date:4/17/2014)... NEW YORK, NY (April 16, 2014) The cause ... but a new study proposes that neurons may be ... own immune system, similar to the way autoimmune diseases ... attack the body,s cells. The study was published April ... is a new, and likely controversial, idea in Parkinson,s ...
Breaking Medicine News(10 mins):Health News:New pain relief targets discovered 2Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Long-term effects of battle-related 'blast plus impact' concussive TBI in US military 2Health News:Is Parkinson's an autoimmune disease? 2
(Date:4/17/2014)... Sodium channels are implicated in many serious conditions such ... important potential target for drug therapies. Unfortunately, there is ... New Cambridge research provides fresh and unexpected insight into ... its components - β-subunit molecules - which are responsible ... is published in the most recent edition of the ...
(Date:4/17/2014)... Current Biology on April 17 have discovered little-known ... insects, which represent four distinct but related species in ... of an animal with sex-reversed genitalia. , "Although ... Neotrogla is the only example in which ... from Hokkaido University in Japan. , During copulation, which ...
(Date:4/17/2014)... is the process whereby the genetic information of ... as proteins, which have numerous different functions in ... important intermediary during gene expression, by relating the ... involved in manufacturing proteins. , By examining ... present in an organism at a given time, ...
Breaking Biology News(10 mins):Structure of sodium channels different than previously believed 2In sex-reversed cave insects, females have the penises 2Rapid and accurate mRNA detection in plant tissues 2
Other TagsOther Tags