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Niacin in Medical News

ConsumerLab.com Warns of Problems with Mulitivitamins and Vitamin Water

... for ingredients such as vitamin A, folic acid, niacin and zinc. Results were reported today on the ... to bone softening and liver problems. ULs for niacin and zinc were also exceeded by some of the products for young children. Excess niacin may cause skin tingling and flushing and high ...

Arena Pharmaceuticals Announces Initiation by Merck of Phase 2 Clinical Trial of Niacin Receptor Agonist

... Phase 2 clinical trial of an orally administered niacin receptor agonist drug candidate being developed ... Arena to treat atherosclerosis. Agonists of the niacin receptor have the potential to regulate plasma ... as well as potential efficacy, of the niacin receptor agonist in patients with dyslipidemia. ...

Amarin Commences First Clinical Trial in Cardiovascular ProgramAmarin Commences First Clinical Trial in Cardiovascular Program

... the co-administration of ultra-pure ethyl EPA and niacin on niacin induced flushing. Flushing is a common side effect of niacin treatment which significantly limits patient ...

GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.

... Treatment Study (FATS), either lovastatin or niacin in combination with a bile acid sequestrant for ... doses (Greater Than or Equal To 1 g/day) of niacin with lovastatin, as these agents can cause ... combined use of lovastatin with other fibrates or niacin should be carefully weighed against the potential ...

Abbott's Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study

... to a combination of Abbott's extended-release niacin combined with simvastatin. The study was ... groups received a 50 mg dose of immediate-release niacin to maintain blinding. Patients in the low-dose ... prescription formulation of niacin for treating abnormal cholesterol levels. ...

Colon cancer shuts down receptor that could shut it down

... the protective cardiovascular effect of niacin, but was activated only if niacin levels in the blood were 1,000 times normal levels. That got the German ... of colon cancer patients who eat a high fiber diet or receive butyrate or niacin therapy along with taking DNA methylation inhibitors that keep GPR109A ...

Drug Combinations Putting Seniors at Risk

... plus aspirin can increase bleeding risk. Atorvastatin (Lipitor) plus niacin can cause muscle weakness, muscle breakdown Simvastatin (Zocor) and niacin can cause muscle weakness and muscle breakdown. Ginkgo plus aspirin can ...

Nuvilex Cites Study that Suggests Red Yeast Rice, an Active Ingredient in Cinnechol, Can Help to Improve Cardiovascular Health

... Cinnechol, which contains red yeast rice extract as well as a blend of other ingredients known to improve cardiovascular function (including niacin and guggul gum extract), may provide a natural alternative for those who have high cholesterol and are intolerant of, or elect not to take, statin ...

Arena Pharmaceuticals to Receive $100 Million from Deerfield Management

... chronically, lorcaserin appears unrivaled in this respect. The value of Arena, however, goes beyond this important drug candidate to the company's niacin receptor program with Merck, its diabetes program with Johnson & Johnson and its ability to discover, develop and partner additional compounds," ...

Abbott Annual Meeting Highlights Outstanding 2008 Results, Continued Strong Outlook

... the first fibrate to be approved for use in combination with a statin, and SIMCOR(R), a fixed-dose combination of Niaspan(R) (Abbott's proprietary niacin extended-release) and simvastatin. Similac Advance EarlyShield(TM), an infant formula with a blend of prebiotics, nucleotides and ...
Niacin in Medical Technology

July 2009 Mayo Clinic Women's HealthSource Highlights Food Storage Safety, Energy Therapies and Vitamins and Minerals

... include: Vitamin B-3 (niacin): niacin helps the body convert food to energy and helps ... Researchers have found that, in high doses, niacin can reduce low-density lipoprotein (LDL or "bad" ... per day, can cause liver damage. High doses of niacin should be considered a prescribed medication and ...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

... unique composition of short-acting oxycodone HCl, niacin and functional inactive ingredients intended to ... , Safety and Tolerability of Escalating Doses of niacin in Fasted and Fed Healthy Adult Volunteers ... HCl, niacin, and other inactive ingredients. The niacin ingredient can generate a temporary, but ...

New Analysis of METEOR Study Demonstrate Effects of AstraZeneca's CRESTOR(R) (Rosuvastatin Calcium) on Atherosclerosis in Patients With Two or More Risk Factors for Cardiovascular Disease

... the patient's individualized goal of therapy. The benefit of further alterations in lipid levels by the combined use of rosuvastatin with fibrates or niacin should be carefully weighed against the potential risks of this combination. Combination therapy with rosuvastatin and gemfibrozil should generally ...

New Data Examines the Effect of Adding a Statin to Optimized Treatment for Patients with Advanced Heart Failure

... the patient's individualized goal of therapy. The benefit of further alterations in lipid levels by the combined use of rosuvastatin with fibrates or niacin should be carefully weighed against the potential risks of this combination. Combination therapy with rosuvastatin and gemfibrozil should generally ...

Isis Pharmaceuticals Updates Its Positive Phase 2 Data for ISIS 301012 in Familial Hypercholesterolemia Patients

... 3.75 g 40 mg lowering 80 mg colesevelam + rosuvastatin + Therapies atorvastatin 1 g niacin 10 mg ezetimibe Age (years) 23 48 32 Lipids: Base- Day % Base- Day % ...
Niacin in Medical Dictionary

High Cholesterol

... or high cholesterol . High cholesterol ( niacin ) niacin is a well-accepted treatment for high ... by: ... Slo-Bid Gyrocaps (Theophylline) Slo- niacin ...

Niacin

... niacin (also known as vitamin B -3) is found in dairy ... and enriched breads and cereals also supply some niacin . Receive our free newsletter or manage your subscriptions Get our RSS news feed ... niacin - Member of the water soluble B vitamin group; ...

Pellagra

... deficiency disease due to a lack of niacin (nicotinic acid ), one of the components of the B complex vitamins in the diet . niacin is plentiful in yeast , organ meats, peanuts, ... that occurs when a person does not get enough niacin (one of the B complex vitamins ) or tryptophan ...

Pyridoxine

... acid and biotin, vitamin B -12, folic acid , niacin ( vitamin B -3), vitamin A , or other ... — thiamin (B-1), riboflavin (B-2), niacin (B-3), pantothenic acid (B-5), pyridoxine ... includes: B1(thiamin), B2 riboflavin ), B3 ( niacin ), B6( pyridoxine ), B12 ( cobalamin ), and ...

Riboflavin

... short limbs and cleft palate . Vitamin B 3 ( niacin , niacin amide) prevents irritability , depression , ... — thiamin (B-1), riboflavin (B-2), niacin (B-3), pantothenic acid (B-5), pyridoxine ...

Thiamine

... The complex also includes: vitamin B 2 niacin vitamin B6 vitamin B12 folate ... ... acid and biotin, vitamin B -12, folic acid , niacin ( vitamin B -3), vitamin A , or other ... al deficiencies -- particularly lack of niacin , thiamine , vitamin C , or vitamin B -12 ...

Vitamin B12

... B1 B2 B6 pantothenic acid folic acid niacin biotin ... The vitamin B12 test is often ...... Folic Acid ( Vitamin B 9) ( Systemic ) niacin ( Vitamin -B3, Nicotinic acid ), niacin amide Pyridoxine ( Vitamin B 6) ( Systemic ) ...

Acid

... the eight B vitamins . The B vitamin c omplex includes vitamins B1, niacin , B6, B12, folate , biotin, and pantothenic acid . Information ... ... stone consisting of the amino acid cystine. Nicotinic acid ( niacin ) and bile acid sequestrants such as cholestyramine are two other ...

Cramp

... or Japanese quince (Chaenomeles speciosa). Supplements of vitamin E , niacin , calcium , and magnesium may also help. Taken at bedtime, they may help ... . - Cramp ing may be relieved by additional intake of calcium and niacin . - Manganese is needed for normal reproduction and the mammary glands ...

Folate

... D, E, and K) and several water-soluble vitamins (the "B" vitamins - niacin , folate , pantothenic acid , and biotin). These vitamins have been ... - A group of vitamins that includes: B1(thiamin), B2 riboflavin ), B3 ( niacin ), B6( pyridoxine ), B12 ( cobalamin ), and folate . [ Med Help ...

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Niacin in Biological News

Niacin's role in maintaining good cholesterol

... research team has uncovered the likely target of niacin (vitamin B3) in the liver, which should provide a ... thus lower the risk of heart disease. While niacin can increase plasma HDL levels, the mechanism of ... has been mysterious, although it's believed that niacin does not actually increase HDL production. Recent ...

Misusing vitamin to foil drug test may be toxic; plus, it doesn't work

... The Children's Hospital of Philadelphia. "Because niacin is known to affect metabolic processes, there is ... of drugs such as cannabis and cocaine. However, niacin is toxic when taken in large amounts." niacin is easily available as an over-the-counter ...
Niacin in Biological Technology

Abbott Receives FDA Approval for SIMCOR(R) (Niaspan(R) / simvastatin), a Novel Combination Medicine for Comprehensive Cholesterol Management

... Niaspan(R) (Abbott's proprietary niacin extended-release) and simvastatin. SIMCOR is ... The study is designed to evaluate the effects of niacin extended- release and simvastatin in reducing ... when treatment with simvastatin monotherapy or niacin extended-release monotherapy is considered ...

Arena Pharmaceuticals Announces Initiation of Phase 1 Clinical Trial of Second Generation Niacin Receptor Agonist Under Its Collaboration With Merck & Co., Inc.

... 1 clinical trial of a second generation oral niacin receptor agonist under a collaboration between ... the therapeutic potential of niacin receptor agonists to treat atherosclerosis and ... investigation of MK-0354, a first generation niacin receptor agonist being evaluated for indications ...

Arena Pharmaceuticals Announces First Quarter 2009 Financial Results

... of a positive randomized, double-blind, placebo-controlled Phase 1 program and the initiation of a Phase 2 clinical trial of a second generation oral niacin receptor agonist intended for the treatment of atherosclerosis in Arena's partnership with Merck. Scheduled Earnings Call ...

Innovative Beverage Products Launches New Product Designed to Enhance the Body's Immune Defense

... include: -- Green tea extract / polyphenols -- Grape seed extract / grape skin extract -- Mushroom extract -- Vitamin C -- niacin / Vitamin B12 -- Vitamin B6 -- Folate -- Zinc -- Sodium "In our research we found consumers were looking for a convenient, ...

Arena Pharmaceuticals Announces First Quarter 2008 Financial Results

... group did not meet the ESMB's predetermined stopping criteria. o Announced the initiation of a Phase 1 clinical trial of a second generation oral niacin receptor agonist intended for the treatment of atherosclerosis in partnership with Merck & Co., Inc. o Entered into strategic agreements with ...

Abbott Annual Meeting Highlights Outstanding 2007 Results, International Growth and Near-Term Pipeline

... in patients with inadequate response to conventional therapy. -- SIMCOR(R), a fixed-dose combination of Niaspan(R) (Abbott's proprietary niacin extended-release) and simvastatin that targets both "good" and "bad" cholesterol in a single pill, was also approved by the FDA in the first ...

Arena Pharmaceuticals Announces Fourth Quarter and Full Year 2007 Financial Results

... in the United States. Arena's 2008 Highlights to Date -- Announced the initiation of a Phase 1 clinical trial of a second generation oral niacin receptor agonist intended for the treatment of atherosclerosis under Arena's partnership with Merck. -- Entered into strategic cooperation ...
Niacin in Biological Definition

Nicotinamide adenine dinucleotide

... charged nitrogen, and one hydrogen attaches to the carbon atom opposite to the nitrogen. The human body synthesises NAD from the vitamin niacin in the form of nicotinic acid or nicotinamide. See also Adenine Nucleotide References and external links NAD and ...

Nicotinamide adenine dinucleotide

... charged nitrogen, and one hydrogen attaches to the carbon atom opposite to the nitrogen. The human body synthesises NAD from the vitamin niacin in the form of nicotinic acid or nicotinamide. See also Adenine Nucleotide References and external links NAD and ...

Nicotinamide adenine dinucleotide

... charged nitrogen, and one hydrogen attaches to the carbon atom opposite to the nitrogen. The human body synthesises NAD from the vitamin niacin in the form of nicotinic acid or nicotinamide. See also Adenine Nucleotide References and external links NAD and ...

Vitamin

... as Vitamin B 7 or Vitamin H . Folate Water Discovered by Lucy Wills in 1933 . Also known as Folic Acid or Vitamin M niacin Water Discovered by Conrad Elvehjem in 1937 . Deficiency causes pellagra . Also known as Vitamin B 3 , Vitamin P or Vitamin PP (for ...
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