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Neuron in Medical News

Famous Names Get Single Neurons Fired Up

... News) -- As you read her name, your Oprah neuron will probably rev up. An international team of ... experiment, Quiroga and his colleagues observed neuron activity in subjects while they looked at three ... to an electronic voice saying "Oprah." A single neuron activated in the hippocampus during the Oprah ...

St. Jude Scientists Discover a New Mechanism Controlling Neuronal Migration

... findings in the July 16 issue of the journal neuron . In the experiments, the researchers ... pulls the internal cell structures of the neuron forward during migration to allow those structures to build the scaffolding that enables the neuron to move the main cell body forward. The ...

Why Huntington's Shows Up in Midlife

... more and transporting more proteins in each neuron than you need," co-principal investigator Scott ... university. "But as you get older and older, the neuron produces and transports less. Each hit diminishes the system further. Eventually, the neuron falls below the threshold needed to maintain cell ...

Membrane fusion at the synapse: Janus faced synaptotagmin-1 helps to keep the fast pace

... fast neurotransmitter release. When the neuron is in a pre-synapse phase, it explodes in ... Transferring neurotransmitters from one neuron to another requires the fusion of the vesicle's ... the sending site, the electrical activity of the neuron needs to be rapidly converted into a chemical ...

Key to treating cancer may be finding its original cell

... the effects of shutting off patched in granule neuron precursors (GNPs), which can only make one ... cerebellum. When they deleted patched in the neuron precursors, 100 percent of the mice developed ... medulloblastoma can be triggered in a granule neuron precursor or a stem cell. But even more ...

Dr. Mei honored by mental health research charity for schizophrenia studies

... laid wrong. Dr. Meis research shows problems in neuron communication, likely also are to blame. Its a ... and, ultimately if the resulting signal the neuron sends is determined by neuregulin-1. His work ... probably does have a powerful role in determining neuron talk. Dr. Mei exemplifies the kind of ...

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Neuron in Medical Technology

Families of Spinal Muscular Atrophy Announces Latest Developments on Three SMA Drug Discovery Programs

... at Paratek Pharmaceuticals to correct gene splicing; and 3) Motor neuron replacement program at California Stem Cell and UCI. These three programs ... the path towards human clinical trials of the drug candidate." Motor neuron Replacement Program: California Stem Cell (CSC) is preparing for a final ...

AIMSPRO is Awarded TGA Orphan Status for the Treatment of Amyotrophic Lateral Sclerosis

... agent AIMSPRO(R) has been awarded Orphan Status for the treatment of Amyotrophic Lateral Sclerosis (ALS). ALS is the most common form of Motor neuron Disease (MND), also known as Lou Gehrig's disease. AIMSPRO has already achieved TGA Orphan Status for the treatment of Krabbe Leukodystrophy ...

Pfizer and Medivation Initiate Phase 3 Trial of Dimebon Added to Donepezil in Patients with Alzheimer's Disease

... thus far, Dimebon has been shown to inhibit brain cell death, potentially by stabilizing and improving mitochondrial function in a way that prevents neuron death and dysfunction. The Dimebon mechanism is thought to be distinct from currently available AD medications. Design of the CONCERT Study ...

AndroScience Corporation Announces Phase 2a Study Results on ASC-J9(TM) for the Treatment of Acne

... using topical based formulations; and prostate cancer, benign prostatic hyperplasia, and spinal bulbar muscular atrophy (Kennedy's Disease - a neuron motor disease caused by AR mutation) utilizing systemic based approaches. AndroScience Corporation www.androscience.com ...

Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS)

... extending the survival of ALS patients by approximately three months. "Initiation of a Phase 2 clinical study of SB-509 in subjects with a motor neuron and muscle disease such as ALS is an obvious next step in the evaluation of this novel therapeutic," stated Dale Ando, M.D., Sangamo's vice president ...

ALS Therapy Development Institute Partners with Clinical Centers to Establish Pathological Mechanisms of Lou Gehrig's Disease

... Donated blood and tissue samples to be used to identify molecular signature of motor neuron disease CAMBRIDGE, Mass., Aug. 19 /PRNewswire-USNewswire/ -- ALS Therapy Development Institute (ALS TDI) announced today the acceleration of an ...
Neuron in Medical Definition

Depolarization-induced suppression of inhibition

... 300-400 µm slice of brain, with intact axons and synapses) where a single neuron is "depolarized" (the normal −70 mV potential across the neuronal membrane ... be caused by the release of endogenous cannabinoids from the depolarized neuron which diffuses to nearby neurons, and binds and activates CB1 receptors, ...
Neuron in Medical Dictionary

ALS

... ALS is a disease of the motor neuron s, those nerve cells reaching from the brain to the spinal cord (upper motor neuron s) and the spinal cord to the peripheral nerve s (lower motor neuron s) that control muscle movement . ALS is ...

Amyotrophic lateral sclerosis

... lateral sclerosis ( ALS ): A classic motor neuron disease . Motor neuron disease s are progressive chronic disease s ... from the progressive degeneration of the motor neuron s. [ Med Help International ] [ Search ] [ Ask ...

Neuron

... neuron -specific enolase (NSE): neuron -specific enolase (NSE) is a substance that has ... tumor s, pancreatic endocrine tumor s, ... neuron al ceroid lipofuscin oses (NCLS) Alternative ...

Synapse

... junction at which a nerve cell (a neuron ) communicates with a target cell . Synapse ... How are the Molecular Components of Central neuron synapse s assembled during development, and how ... of synapse s that receive signals from other neuron s and relay information to the soma. ...

Lateral

... , is a progressive disease of the nervous system. Nerve cells, called neuron s, are located in the spinal cord and brain and normally give signals to ... away of certain nerve cells of the brain and spinal column called motor neuron s. Lateral col lateral ligament (LCL) - The LCL supports the outer ...

Multi

... immune cells attack and destroy the myelin sheath that insulates neuron s in the brain and spinal cord. Multi ple personality was first ... both leads to and builds upon the RN designation is essential. Each neuron has one axon, which is wrapped in multi ple layers of a substance called ...

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Neuron in Biological News

Huntington's disease deciphered

... show what effect activation of that enzyme has on neuron function. Huntington's disease is an adult ... of axonal transport, the system within the neuron that shuttles proteins from the cell body where ... more and transporting more proteins in each neuron than you need," Brady said. "But as you get older ...

Tiny but toxic: MBL researchers discover a mechanism of neurodegeneration in Alzheimer's disease

... the loss of functional connections. It's when the neuron is no longer talking to its targets that you ... for their release) from place to place in the neuron on microtubule tracks. Brady's findings are ... at the synapse the point where the neuron connects to its target. "Disruptions in the ...

Mayo Clinic: Brain disorder suggests common mechanism may underlie many neurodegenerative diseases

... cargo efficiently over the lifetime of a neuron is fundamentally important, says Dr. Farrer. ... in amyotrophic lateral sclerosis (ALS), a motor neuron disease also known as Lou Gehrig's disease, the ... with frontotemporal dementia or with motor neuron disease. What these clumps represent is not ...

Chemist receives NIH funding to unravel tricks of neuronal wiring

... build a substrate that looks like what a growing neuron would encounter in the brain as it goes from the ... can watch in real time, with a microscope, how a neuron is guided through this pattern." Their ... neurobiological milieu. By watching the neuron grow in real time, he will be able to determine ...

Our unconscious brain makes the best decisions possible

... are published in today's issue of the journal neuron . Neuroscientists Daniel Kahneman and Amos ... right within the jumble of other random dots, the neuron coding for "rightward movement" would occasionally fire. As the test continued, the neuron would fire more and more frequently until it ...

Streamlining brain signals for speed and efficacy

... published in the current issue of the journal neuron , researchers at the Salk Institute for ... they found that no matter how fast the sensory neuron was firing, the same amount of neurotransmitter ... And instead of vacillating, the post-synaptic neuron took the information and transmitted it ...

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Neuron in Biological Technology

Families of Spinal Muscular Atrophy; University of California, Irvine Stem Cell Scientist; and California Stem Cell Announce Collaboration for Safety Studies for Stem Cell Therapy in Spinal Muscular Atrophy

... FDA regulations, will assess the safety of motor neuron progenitors derived from human stem cells ... large population of clinical-grade motor neuron progenitors required for these pivotal studies ... progenitor replacement in animal models of motor neuron disease. This builds on the pioneering work ...

Oprah, Luke Skywalker and Maradona -- new study investigates how our brains respond to them

... of the same individual using different sensory prompts. For example a neuron responded to three pictures of the TV host "Oprah Winfrey", to her name ... name of "Luke Skywalker", from the classic movie "Star Wars". Another neuron fired strongly to the pictures and the written and spoken name of the ...

PTC Therapeutics and Spinal Muscular Atrophy Foundation Announce $8.5 Million Small Molecule Development Collaboration

... the potential to treat SMA by increasing production of the survival motor neuron (SMN) protein. The lack of the SMN protein causes SMA. Total funding for ... About Spinal Muscular Atrophy Spinal muscular atrophy (SMA) is a motor neuron disease and the leading genetic cause of death among infants and toddlers. ...

Sandia researchers construct carbon nanotube device that can detect colors of the rainbow

... transistor made from a single-walled carbon nanotube. "In our eyes the neuron is in front of the retinal molecule, so the light has to transmit through the neuron to hit the molecule," says Sandia researcher Xinjian Zhou. "We placed the ...

Solace Pharmaceuticals Appoints Professor David Julius, Renowned Pain Physiologist, to Scientific Advisory Board

... called TRPV1, on sensory nerve endings, and that TRPV1 functions as a molecular integrator of physical and chemical signals that regulate sensory neuron excitability under both normal and pathophysiological conditions. Following a similar paradigm, Professor Julius' research showed that a menthol ...

Medivation Completes Enrollment in Confirmatory, Pivotal Phase 3 'CONNECTION' Trial of Dimebon in Patients With Alzheimer's Disease

... thus far, dimebon has been shown to inhibit brain cell death, potentially by stabilizing and improving mitochondrial function in a way that prevents neuron death and dysfunction. The dimebon mechanism is thought to be distinct from that of currently available Alzheimer's disease medications. In ...

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Neuron in Biological Products

Digital Clamp One Electrophysiology Feedback Unit from myNeuroLab.com

Description:... Clamp One has been used to stimulate a quiescent neuron whenever a different and active neuron fires, forcing it to fire. One neuron can drive another through the Digital Clamp One. ...
Company:myNeuroLab.com

Digital Clamp One from myNeuroLab.com

Description:... Clamp One has been used to stimulate a quiescent neuron whenever a different and active neuron fires, forcing it to fire. One neuron can drive another through the Digital Clamp One. ...
Company:myNeuroLab.com

Mouse Dopaminergic Neuron Differentiation Kit, 2nd Generation from R&D Systems

Description:... effective source of neural precursors for DA neuron generation. Embryonic stem (ES) cells, derived ... identifying conditions required for functional DA neuron differentiation of ES cells. Experimental models ... DESIGN OF THE KIT The Mouse Dopaminergic neuron Differentiation Kit is a system designed for in ...
Company:R&D Systems

Rabbit Anti-Neuron navigator 1 Polyclonal Antibody, Unconjugated from Abcam

Description:... Rabbit polyclonal to neuron navigator 1 ( Abpromise for all tested applications). Antigen: ... to KLH derived from within residues 1850 to the C-terminus of Mouse neuron navigator 1. (Note: the amino acid sequence is proprietary) (Peptide ...
Company:Abcam

Human Neural Stem Cell Functional Identification Kit from R&D Systems

Description:... media supplements, which can be used for the short-term maintenance, differentiation, and expansion of NSCs and the induction of NSCs into astrocyte, neuron and oligodendrocyte lineages. An antibody panel consisting of mouse anti-human Nestin, mouse anti-human Glial Fibrillary Acidic Protein (GFAP), mouse ...
Company:R&D Systems

Mouse/Rat Neural Stem Cell Functional Identification Kit from R&D Systems

Description:... formulated media supplements, which can be used for the short-term maintenance and expansion of NSCs and the differentiation of NSCs into astrocyte, neuron and oligodendrocyte lineages. An antibody panel consisting of goat anti-rat Nestin, sheep anti-human Glial Fibrillary Acidic Protein (GFAP), mouse ...
Company:R&D Systems

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Neuron in Biological Definition

Cell growth

... cell body, axon and dendrites. In vertebrates , neuron size is often a reflection of the number of synaptic contacts onto the neuron or from a neuron onto other cells. For example, the size of ...

Neuron

... carries nerve signals away from the neuron. Each neuron has only one axon, but this axon may undergo ... branching arbor of cellular extensions. Each neuron has very many dendrites with profuse dendritic ... of protein synthesis. The cell body of a neuron is supported by a complex meshwork of structural ...

Synapse

... they operate. Only the so-called pre-synaptic neuron secretes the neurotransmitter, which binds to ... strong, an action potential in the pre-synaptic neuron will trigger another in the post-synaptic cell; ... potential initiation. In the brain, however, each neuron typically connects or "synapses" to many others, ...

Neurotransmitter

... electrical signals between a presynaptic and a postsynaptic neuron . A chemical is classified as a neurotransmitter if it respects the ... endogenously It is available in sufficient quantity in the presynaptic neuron to exert an effect on the postsynaptic neuron Externally administered, ...

Olfaction

... like bananas ), whereas some others cannot. Each olfactory receptor neuron in the nose expresses only one functional odor receptor. According to ... Laurent, G (2003) Intensity versus Identity Coding in an Olfactory System, neuron 39, 991-1004. Stopfer, M. and Laurent, G. (1999). Short-term memory in ...

Selective serotonin reuptake inhibitor

... neurons (nerve cells) via a synapse , a small gap between the cells. The neuron that sends the information releases neurotransmitters (with serotonin ... Depression has been linked to a lack of stimulation of the recipient neuron at a synapse. To stimulate the recipient cell, SSRIs inhibit the reuptake ...

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Neuron in Biological Dictionary

Sensory neurons

... as light, sound, temperature, ... A neuron OOR-on, also known as a neurone or nerve cell) ... components of the brain, ... Sensory neuron summary with 3 pages of encyclopedia entries, ... the properties of an artificial sensory neuron . ... The purpose of sensory neurons is to ...

Reflex arc

... The neural path of a reflex . ... In a three neuron reflex arc list the direction and the stages ... reflected. Physiology. Being an ... In a three neuron reflex arc list the direction and the stages ... arc consists of only two neurons (one sensory neuron and one motor ... Definition of Reflex - arc ...

Neuron

... A neuron OOR-on, also known as a neurone or nerve cell) ... are the core components of the brain, ... neuron is a simulation environment for modeling ... W. Moore, and Ted Carnevale at Yale and Duke. neuron Systems LLC. energy research. robotics. control ...

Motor neuron

... In vertebrates, the term motor neuron (or motoneuron) classically applies to neurons ... the basal plate (basal lamina) of ... Motor neuron ... NIF Search - Alpha Motor neuron via the Neuroscience Information ... ( The ...

Cell body

... Greek, meaning " body "; the soma of a neuron is often called the " cell body ". ... it, and the body's organ systems are ... neuron - Neuronal Cell Body ,Organelles found in a ... cell , and allows you to compare prices ... neuron cell bodies basically have the same ...

Resting potential

... potential ) across the plasma ... 1. The resting potential of a neuron is due mostly to. saltatory conduction ... The Resting Potential . ... from differences between sodium and potassium ... Two properties of the neuron membrane permit a resting potential : ... They are primarily ...

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