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Neurogenic in Medical News

Tengion to Present at 27th Annual JP Morgan Healthcare Conference

... Tengion's completion of its Phase 2 clinical trial in patients with neurogenic bladder due to spina bifida and the company's plans for a Phase 3 trial of its Tengion Neo-Bladder Augment(R) in patients with neurogenic bladder, planned for initiation in the first half of 2009. Dr. ...

UQ research finds speech disorders can be assessed from a distance

... and reliably assessed over the internet using a telerehabilitation application. "Having worked clinically with people living with an acquired neurogenic communication disorder, I saw how frustrating it was for both the person with the communication disorder and the clinician if access to these ...

Japanese encephalitis virus causes 'double trouble' to brain

... said Basu. He also went on to state, "The neurological and cognitive deficits in the JE survivors could be related to the drop in NPC cells in the neurogenic region of the brain called the subventricular zone". Neural stem/progenitor cells are the saviours of the brain following any insult or infection ...

JCI table of contents: June 20, 2008

... activated TRPA1, suggesting that they might contribute to the airway damage that occurs in smoke-related diseases. TITLE: Cigarette smokeinduced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents AUTHOR CONTACT: Pierangelo Geppetti University of ...

Erectile Dysfunction a Strong Harbinger of Heart Trouble

... E. Scott Monrad, a professor of clinical medicine at Albert Einstein College of Medicine in New York City. "Neuropathy would interfere with the neurogenic responses feeding into proper erection," Monrad said. "And obstruction of blood flow into the arteries reduces the pressure needed to achieve ...

Scientists obtain anticancer medicines from the elecampe, a wild plant growing in the Mediterranean

... Institute of the University of Granada have found out that the plant Dittirichia viscose, known as elecampe, can be used to obtain inhibitors of neurogenic vasodilatation, a significant progress in migraine and cancer treatments. The study, supervised by professors Mara del Mar Herrador and ...

A New Approach In Treatment Neurogenic Detrusor Overactivity In Children

... (BTX-A) detrusor injections in patients with neurogenic or nonneurogenic detrusor overactivity. BTX-A ... have been described in adult// patients with neurogenic detrusor overactivity due to spinal cord injury. ... same experiments successfully in children with a neurogenic bladder. After many reports of this “wonder ...

Brain Swelling Key to Reducing Stroke Fatalities

... in the brain is unclear. But in the skin, a similar process known as neurogenic inflammation is triggered by nerve cells. This results in increased ... Blocking substance P reduces skin tissue oedema. “Until recently, neurogenic inflammation was not known to occur in the brain following injury. Our ...

Stem Cell Activity Deciphered in the Aging Brain

... memory function in the elderly. One approach being explored is to treat older rats with drugs designed to mimic the action of compounds called neurogenic factors, which encourage stem cells in the brain to divide, Shetty said. The researchers also are grafting neural stem cells grown in culture dishes ...
Neurogenic in Medical Technology

Unlikely Treatment Identified by BrainCells Neurogenesis Platform Improved Clinical Outcomes in Patients Suffering From Depression

... "BCI-952 was selected by our proprietary platform for the compound's neurogenic properties," said Jim Schoeneck, chief executive officer of BrainCells ... screening platform, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successful clinical trials in a ...

BrainCells Inc. Initiates Phase 2 Clinical Trial with BCI-540 for Depression with Anxiety

... understanding of the power of neurogenesis coupled with our proprietary neurogenic platform technology to identify a strong portfolio of clinical candidates, ... screening platform, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successful clinical trials in a ...

Tengion Launches Third Phase 2 Clinical Trial of Regenerated Human Bladder

... of enrollment of a Phase 2 clinical trial of the Neo-Bladder Augment for neurogenic bladder due to spina bifida and the initiation of a Phase 2 clinical trial of the Neo-Bladder Augment for neurogenic bladder due to spinal cord injury. According to The World Journal of ...

Preclinical Data Demonstrate Ability to Regenerate an Entire Bladder With Tengion Neo-Bladder Replacement(TM)

... three Phase 2 clinical trials of its Neo-Bladder Augment at 12 leading academic medical centers across the United States: one in children with neurogenic bladder due to spina bifida, one in adults with neurogenic bladder due to spinal cord injury and one in adult patients with overactive bladder (OAB) ...

Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ

... clinical trial of its neo-bladder construct, derived from a patient's own cells. The U.S.-based study is being conducted in 10 adult patients with neurogenic bladder due to spinal cord injuries. Neurogenic bladder is a condition that can occur due to spinal cord injury and may lead to kidney failure and ...
Neurogenic in Medical Products

Cook® Continence Cuff

Description:... Used for temporary control of male urinary incontinence due to surgery or neurogenic disorder. Supplied non-sterile. Reusable. Intended for single patient use ....
Company:Cook Urological
Neurogenic in Medical Dictionary

Neurogenic bladder

... neurogenic bladder Definition: neurogenic bladder is a urinary problem in which there is ... retention or incontinence of urine . neurogenic BLADDER - A dysfunction of the bladder due a ...

Bladder stones

... problem such as urinary tract infection , bladder diverticulum, neurogenic bladder , or an enlarged prostate . Approximately 95% of all bladder ... diabetes mellitus epilepsy lower urinary tract obstruction neurogenic bladder , which is a bladder with impaired nerve function sleep ...

Rapidly progressive

... the liver and resulting in death . Charcot foot is the term given to neurogenic arthropathy that affects the joints in the foot. neurogenic arthropathy is a rapidly progressive degenerative arthritis that ...

Anaphylactic shock

... shock (caused by inadequate blood volume) anaphylactic shock (caused by allergic reaction) septic shock (associated with infections ) neurogenic shock (caused by damage to the nervous system) ... Individuals who have a large local reaction are likely to have a similar response to ...

Bladder

... health first . bladder stones constipation diabetes insipidus diabetes mellitus epilepsy lower urinary tract obstruction neurogenic bladder , which is a bladder with impaired nerve function sleep apnea , which is a breathing disorder that occurs during sleep ... Swim ...

Chloride

... manufacturer's instructions about cleaning and changing them. oxybutynin chloride syrup For treatment of bladder symptoms associated with neurogenic bladder , including frequency, urgency, urge incontinence , dysuria and urinary leakage. Mfg: Morton Grove Pharmaceuticals. Source: PR Newswire - ...

Diabetes insipidus

... diabetes insipidus and for the management of the ... diabetes insipidus diabetes mellitus epilepsy lower urinary tract obstruction neurogenic bladder , which is a bladder with impaired nerve function sleep apnea , which is a breathing disorder that occurs during sleep stress ... ...

Hypovolemic shock

... shock (caused by inadequate blood volume) anaphylactic shock (caused by allergic reaction) septic shock (associated with infections ) neurogenic shock (caused by damage to the nervous system) ... Aortic rupture Bleeding from the aorta Hypovolemic shock Arterial embolism ...

Incontinence

... (Loss of Bladder Control) Bladder Control for Women Cystocele: Fallen Bladder Cystoscopy and Ureter oscopy Interstitial Cystitis neurogenic Bladder Treatment s for Urinary Incontinence in Women Urinary Incontinence in Children ... Incontinence in the Elderly: What a ...

Language Disorders

... ed. Handbook of Neurological Speech and Language Disorders . New York: Marcel Dekker, Inc., 1995. LaPointe, Leonard L., ed. Aphasia and Related neurogenic Language Disorders . 2nd ed. New York: Thieme, 1997. Some children with cerebral palsy also have learning, vision , hearing and language ...

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Neurogenic in Biological News

UT Southwestern researchers create molecule that nudges nerve stem cells to mature

... completely serendipitous that we uncovered this neurogenic [nerve-creating] small molecule," Dr. Hsieh said. "I think it's one of the most powerful neurogenic small molecules on the planet. In theory, this ... non-nerve cells and was more potent than other neurogenic substances in stimulating nerve-cell development. ...

Drug-proof zebrafish reveal secrets of addiction

... known for their involvement in brain development. Even more interestingly, as the authors demonstrate, several of these genes are expressed in neurogenic domains of the adult fish brain these are domains where neurons are generated from neural stem cells during adulthood. According to the researchers, ...

Ex vivo neural stem cell expansion

... Sloan-Kettering Cancer Center) and colleagues lend new mechanistic insight into the effective generation of neural stem cells outside of the neurogenic niche. Their upcoming paper demonstrates that the polycomb group protein, Bmi-1, maintains forebrain neural stem cell self-renewal. Overexpression ...

Stress may make you itch

... that stress may activate immune cells in your skin, resulting in inflammatory skin disease. The related report by Joachim et al., "Stress-induced neurogenic Inflammation in Murine Skin Skews Dendritic Cells towards Maturation and Migration: Key role of ICAM-1/LFA-1 interactions," appears in the November ...

Trainor Lab characterizes gene essential for prenatal development of nervous system

... in the spinal cord by coupling progression through the cycle of cell division with differentiation of neural cells by direct activation of two key neurogenic determinants, Neurod and p27Kipl. We were excited to uncover, for the first time, multiple functional roles for a Cux-like homeodomain ...

Jefferson urologists studying regenerated neo-bladder to help spinal cord injury patients

... To participate in the study, a patient must be 18 to 65 years of age, have had a spinal cord injury for more than a year and diagnosed with a neurogenic bladder that is not adequately responding to medical therapy. The urologist first performs a biopsy on the patient to retrieve the cells. The ...

Stem cell activity deciphered in the aging brain

... memory function in the elderly. One approach being explored is to treat older rats with drugs designed to mimic the action of compounds called neurogenic factors, which encourage stem cells in the brain to divide, Shetty said. The researchers also are grafting neural stem cells grown in culture dishes ...
Neurogenic in Biological Technology

BrainCells Inc. Appoints Philip Jochelson, M.D. Chief Medical Officer and Jason Levin Chief Business Officer

... drug candidates based on what we know about their neurogenic properties from our platform that enables us to ... complex pharmacology, and image and measure the neurogenic process. Philip and Jason are top caliber people ... BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for ...

REVISED: BrainCells Inc. Expands Series B Financing to $50 Million

... platform technology to identify the compound's neurogenic profile, which is comparable to antidepressants ... needs, we find BCI's ability to leverage its neurogenic screening technology to identify and develop new ... BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for ...

BrainCells Inc. Expands Series B Financing to $50 Million

... platform technology to identify the compound's neurogenic profile, which is comparable to antidepressants ... needs, we find BCI's ability to leverage its neurogenic screening technology to identify and develop new ... BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for ...

Preclinical Efficacy Data Demonstrate Ability of Tengion's Neo-Bladder Augment to Restore Bladder Function

... Augment: one in pediatric patients with neurogenic bladder due to spina bifida, and the other in adult patients with neurogenic bladder due to spinal cord injuries." The ... Augment: one in pediatric patients with neurogenic bladder due to spina bifida, and the other ...

BrainCells Inc. Appoints David E. Thompson to Its Board of Directors

... and operations will be a great asset to us as we continue to expand our neurogenic platform technology and to explore potential strategic collaborations." ... effects. BCI-540 was in-licensed from Mitsubishi Pharma (MPC) based on its neurogenic properties and in previous studies was shown to be well tolerated in more ...

Tengion Announces European Orphan Drug Designation for Neo-Bladder Augment

... clinical benefit to those patients with spina bifida who suffer from neurogenic bladder and warrant surgical intervention for their condition. "We are ... Neo-Bladder Augment's potential to significantly improve the treatment of neurogenic bladder in spina bifida patients -- a critically underserved patient ...

Neuralstem Fills Key Product Development Position

... targeting diseases and injuries of the spinal cord for its first human trials, including ALS and Paraplegia. The company has also developed neurogenic and neuroprotective small molecule compounds targeted at treating depression. For further information, please visit http://www.neuralstem.com . ...

BrainCells Inc. Completes $30 Million Initial Closing of Series B Financing

... human brain produce new brain tissue, including neurons. With its predictive screening platform, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successful clinical trials in a variety of CNS indications. For more information, visit ...
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