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Nephropathy in Medical News

Targeted drug therapy found effective in patients with common form of immune-mediated kidney disease

... be healed in some patients. Membranous nephropathy (also known as membranous glomerulopathy) is one ... colleagues treated 50 patients with membranous nephropathy with rituximab. The investigators found that 10 ... demonstration that kidney injury in membranous nephropathy can regress after selective depletion of B cells. ...

JCI online early table of contents: Jan. 2, 2008

... is prematurely sialylated in individuals with IgA nephropathy Among individuals with the relatively common ... from the peripheral blood of patients with IgA nephropathy and demonstrated that premature sialylation is ... IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1 AUTHOR ...

Immunoglobulin Can Predict Some Diabetic Complications

... complications in people with type 1 diabetes who have diabetic nephropathy (DN) -- kidney damage caused by diabetes. The study included 139 ... The MedlinePlus Medical Encyclopedia has more about diabetic nephropathy . -- Robert Preidt ...

PLC Medical Systems Announces Publication of Care Study Update

... in Renally Impaired Patients (CARE) Study determined that Contrast-Induced nephropathy (CIN) is associated with long-term adverse events, ranging from pulmonary ... RenalGuard as a safe and effective prevention device for contrast induced nephropathy may not be completed in a timely fashion, if at all, or, if these clinical ...

New Test May Help Kidney Transplant Patients

... viral aggregates that form in the kidneys of people with polyomavirus nephropathy and are excreted in the urine. The researchers said the test takes ... of Nephrology . "An early and accurate diagnosis of polyomavirus nephropathy will result in a better understanding of the disease and ultimately ...

Halpin Foundation and the ASN announce recipient of Halpin Foundation-ASN research grant

... led to the creation of a fund to promote research relevant to membranous nephropathy in 2004. The Halpin Foundation dedicated itself to the study of this ... "Unfortunately, there are many unanswered questions surrounding membranous nephropathy and nephrotic syndrome, and we are grateful to The Halpin Foundation for ...

Late-breaking results of clinical trial on therapeutic endovascular cooling reported at TCT 2008

... Late-breaking results from the COOL RCN (COOLing to Prevent Radio Contrast nephropathy in Patients Undergoing Diagnostic or Interventional Catheterization) Trial ... exposure to intravascular contrast agents is known as radiocontrast nephropathy (RCN). Principal Investigator Gregg W. Stone, M.D., CRF Chairman, ...

Study: Before a CT scan or angiogram, many people should take inexpensive drug to protect kidneys

... go up when the kidneys arent operating efficiently. Contrast-induced nephropathy is defined as a 25 percent or greater increase in creatinine within 48 ... as a surrogate for kidney function. The problem of contrast-induced nephropathy is a relatively recent one a byproduct of the dramatic increase in the ...

PLC Systems Reports First Quarter 2009 Results

... clinical trial in Italy and the planned future U.S. clinical trial for RenalGuard as a safe and effective prevention device for contrast induced nephropathy may not be completed in a timely fashion, if at all, or, if these clinical trials are completed, they may not produce clinically significant or ...

PLC Systems Reports Fourth Quarter 2008 Results

... the EU launch and in raising additional funding for the U.S. clinical trial to investigate the efficacy of RenalGuard in preventing Contrast Induced nephropathy (CIN)." Mr. Tauscher added, "Our core TMR business in the U.S. continues to provide a base level of revenues, primarily through kit sales and ...

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Nephropathy in Medical Technology

Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy

... will enroll up to 30 patients diagnosed with IgA nephropathy at clinical sites in Canada. The trial design ... role in inflammatory kidney diseases such as IgA nephropathy and diabetic nephropathy, as well as a variety of ... every other day for 15 doses. About IgA nephropathy ...

PLC Systems Announces Approval of First European Study to Evaluate RenalGuard(TM)

... in the prevention of Contrast-Induced nephropathy (CIN) in high-risk patients undergoing ... be provided using RenalGuard. "Contrast-Induced nephropathy is a risky complication resulting from the use of ... medical condition known as Contrast-Induced nephropathy (CIN). Patients undergoing ...

Keryx Biopharmaceuticals Completes SUN-MICRO Phase 3 Pivotal Trial

... pathological albumin excretion in diabetic nephropathy in humans. Some of the members of this chemical ... to sulodexide for the treatment of diabetic nephropathy in North America, Japan and certain other markets outside of Europe. Diabetic nephropathy is a long-term complication of diabetes in which ...

Sulodexide Data Safety Monitoring Committee Completes Additional Review of Phase 3 Study Data

... pathological albumin excretion in diabetic nephropathy in humans. Some of the members of this chemical ... to use Sulonex(TM) for the treatment of diabetic nephropathy in North America, Japan and certain other markets outside of Europe. Diabetic nephropathy is a long-term complication of diabetes in which ...

Powerful New Efficacy Data in Moderate and Severe Hypertensive Patients Supports FDA Approval of AVALIDE(R) (Irbesartan-Hydrochlorothiazide) as the First Combination Therapy for Initial Use in Patients Likely to Need Multiple Drugs to Achieve Their Blood

... and also helps to slow the progression of nephropathy in type 2 diabetic hypertensive patients. AVALIDE ... is also indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria ... AVAPRO reduces the rate of progression of nephropathy as measured by the occurrence of doubling of ...

PLC Medical Systems to Demonstrate RenalGuard(R) at EuroPCR 2009

... to demonstrate how RenalGuard is used to help prevent Contrast-Induced nephropathy (CIN) in a patient with impaired renal function undergoing a Percutaneous ... RenalGuard as a safe and effective prevention device for contrast induced nephropathy may not be completed in a timely fashion, if at all, or, if these clinical ...

PLC Systems Receives Full FDA Approval for Pivotal Study of RenalGuard(TM) in The U.S.

... System(TM) and associated therapy in the prevention of Contrast-Induced nephropathy (CIN). The FDA also approved PLC's request to expand their ... in the trial will now include 406 patients. Contrast-Induced nephropathy Approximately seven million patients worldwide undergo ...

Phase 2 Trial Results for Exelixis' XL784 Presented at the 2007 American Society of Nephrology Conference

... enzymes that may play a role in the pathogenesis of diabetic nephropathy and renal fibrosis. The data were presented during a poster session ... mortality, particularly in patients with diabetes and/or hypertension. nephropathy (kidney disease) is a common problem in diabetic patients, often leading ...

Research: Popular Diabetes Medications Associated with Increase in Bone Fractures

... people with diabetes. The American Diabetes Association recommends ACE-I or ARB in diabetic patients with certain clinical conditions such as nephropathy or hypertension. Unfortunately, these agents are not frequently prescribed to many patients for whom treatment is indicated. In the Medco study, a ...

RenalGuard(R) Pilot Safety Clinical Trial Data to be Presented at ACC 2009

... to test the safety of the RenalGuard System(TM) when used to provide high volume matched diuresis in patients at high risk for Contrast-Induced nephropathy (CIN) undergoing angiography. A total of 23 patients were enrolled in the study, which was completed in late 2007. The lead investigator for the ...
Nephropathy in Medical Products

ImmunoDip Test For Microalbuminuria

Description:... for independent verification of these results. Early detection of low levels of urinary albumin allows early intervention in cases of Subclinical nephropathy in Diabetes and Hypertension. Microalbuminuria is now accepted as highly predictive of cardiovascular risk in hypertensive ....
Company:Diagnostics Chemicals Limited
Nephropathy in Medical Definition

Pathology

... type 2 , coma , angiopathy , ketoacidosis , nephropathy , neuropathy , retinopathy ) - Hypoglycemia - ... Hypertensive heart disease - Hypertensive nephropathy - Secondary hypertension - Renovascular ... Focal segmental glomerulosclerosis | Diabetic nephropathy | ...
Nephropathy in Medical Dictionary

Analgesic nephropathy

... Analgesic nephropathy (Painkillers and the Kidney s) An analgesic ... intended to relieve pain . Analgesic nephropathy Definition: Analgesic nephropathy involves damage to one or both kidney s caused ...

Diabetic retinopathy

... Related Encyclopedia Topics: Diabetic nephropathy , Diabetic Neuropathy , Diabetic Retinopathy , ... (CHD; e.g., atherosclerosis ) Diabetic nephropathy Diabetic neuropathy Diabetic retinopathy ... diabetes -related indications (e.g., diabetic nephropathy , diabetic retinopathy ). ...

IgA nephropathy

... IgA nephropathy is a kidney disorder caused by deposits of the ... glomeruli (filters) within the kidney . IGA nephropathy - This is a form of glomerulonephritis that ... ( glomerulonephritis ) is the result. IgA nephropathy is a chronic kidney disorder caused by ...

Immunoglobulin

... can result from kidney disorders such as IgA nephropathy or IgM nephropathy . It can also occur in other disorders such as ... pain more easily. Diagnosis of membranous nephropathy requires a kidney biopsy , which reveals ...

Membranous nephropathy

... Membranous nephropathy may be a primary renal disease of ... associated with other conditions. membranous nephropathy (neh-FROP-uh-thee): A disorder that hinders the ... deposits on the glomerular membrane . nephropathy , membranous: See: ...

Nephropathy

... nephropathy , membranous: See: Membranous nephropathy . Search All of MedicineNet For: search help Printer-Friendly Format ... IgA nephropathy is a kidney disorder caused by deposits of ...

Reflux nephropathy

... Reflux nephropathy Definition: Reflux nephropathy is a condition in which the kidney s are ... is unknown but some cases can result from reflux nephropathy . The clinical manifestation of this kidney ...

Retinopathy

... (CHD; e.g., atherosclerosis ) Diabetic nephropathy Diabetic neuropathy Diabetic retinopathy ... heart disease strokes kidney disease ( nephropathy ) impotence peripheral vascular disease ... diabetes -related indications (e.g., diabetic nephropathy , diabetic retinopathy ). ...

Alport syndrome

... UTI ( pyelonephritis ) Dementia due to metabolic causes Diabetic nephropathy / sclerosis Digitalis toxicity End-stage renal disease Epilepsy ... UTI ( pyelonephritis ) Dementia due to metabolic causes Diabetic nephropathy / sclerosis Digitalis toxicity End-stage renal disease Epilepsy ...

Atheroembolic renal disease

... UTI ( pyelonephritis ) Dementia due to metabolic causes Diabetic nephropathy / sclerosis Digitalis toxicity End-stage renal disease Epilepsy ... UTI ( pyelonephritis ) Dementia due to metabolic causes Diabetic nephropathy / sclerosis Digitalis toxicity End-stage renal disease Epilepsy ...

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Nephropathy in Biological News

Enzyme involved in inflammatory bowel disease discovered at Penn State College of Medicine

... meprin proteases. With colleagues from the National Institutes of Health, she found a linkage between the meprin gene and vulnerability to diabetic nephropathy in Pima Indians in the southwestern United States. "These types of transitional research that provide sound basic understanding of a disease ...

Researchers may have found why women have an edge on salt-sensitive hypertension

... in some patients taking powerful new ETA antagonists, which are in use for pulmonary hypertension and under study for conditions such as diabetic nephropathy and uncontrolled hypertension. These antagonists block the action of ETA receptors which are believed to raise blood pressure and help reshape blood ...

Joslin discovers signs of residual islet cell function in people with long-term type 1 diabetes

... of type 1 diabetes 57 years. The data collected so far show that individuals who have survived 50 years or more have a greatly reduced risk of nephropathy and retinopathy. ...

Genetically engineered animals help in scientific research that may benefit children

... us to decide which molecules to study, or which might be interesting targets for drug development in human chronic kidney disease." Obstructive nephropathy or obstructive uropathy, the kidney disease on which this animal model is based, is frequently found in children and is the first cause of end-stage ...

New type of rejection blocker protects kidneys after transplant

... both the intensive and less intensive belatacept regimens compared to cyclosporine patients. Another indicator of kidney health, chronic allograft nephropathy (scarring of the kidney), also was lower at 12 months among patients receiving either of the belatacept regimens. Patients in all treatment ...
Nephropathy in Biological Technology

Synvista Therapeutics Announces Initiation of the BREAK Study of Alagebrium for Diastolic Heart Failure

... of the heart, kidney and other tissues leading to heart failure, diabetic nephropathy and other disorders. It is a proprietary A.G.E. crosslink breaker that ... company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several ...

Synvista Therapeutics to Present at Acumen BioFin Rodman & Renshaw 5th Annual Global Healthcare Conference

... in cardiovascular diseases, alagebrium in heart failure and diabetic nephropathy and progress on the company's Haptoglobin diagnostic test. He will also ... company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several ...

BioMarin and IGAN Biosciences to Collaborate on Development of an Enzyme Therapy to Treat IgA Nephropathy, a Rare and Life-Threatening Kidney Disease

... to add this program to our growing product development pipeline. The IgA nephropathy indication aligns well with our development and commercial competencies as ... manufacturing and process development infrastructure and expertise." IgA nephropathy or Berger's disease is a primary glomerulonephritis characterized by ...

Astellas Receives FDA Approval for Use of Prograf(R) (Tacrolimus) in Conjunction With Mycophenolate Mofetil (MMF) in Kidney Transplant Recipients

... is suspected or diagnosed, immediate reduction of immunosuppression is advised. Activation of latent viral infections, including BK virus-associated nephropathy and JC virus-associated progressive multifocal leukoencephalopathy (PML), has also been reported. These viral infections may lead to serious, ...

Pharmalink AB Completes Phase II Clinical Study With Renal Disease Drug Nefecon(R)

... World Congress of Nephrology 2009, 22-26 May in Milan (Smerud et al, Enteric Budesonide Ameliorates Albuminuria and Glomerular Filtration Rate in IgA nephropathy Patients) and at the satellite meeting, IgA Nephropathy, 26-28 May in Stresa, Italy. "It is very gratifying to have completed this important ...

Nile Therapeutics Announces Focus on CD-NP for Acute Heart Failure and Termination of 2NTX-99 Program

... suggests potential utility in a range of atherosclerotic, thrombotic, and microvascular diseases, including intermittent claudication, diabetic nephropathy and pulmonary arterial hypertension. About Nile Therapeutics Nile Therapeutics, Inc. is a clinical-stage biopharmaceutical company that ...

Synvista Therapeutics Announces Progress in Phase 2 Clinical Trial Program for Alagebrium

... candidate for interfering with A.G.E.-related sclerosis and fibrosis of the heart, kidney and other tissues leading to heart failure, diabetic nephropathy and other disorders. It is a proprietary A.G.E. crosslink breaker that is designed to function unlike any previously developed pharmaceutical agents ...

Synvista Therapeutics Increases Commercial Focus by Appointing David C. Tantillo Senior Director of Marketing and Sales

... About Synvista Therapeutics Synvista Therapeutics is a biopharmaceutical company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several product candidates that represent novel approaches to some of the largest ...

PLC Systems to Host First Quarter Conference Call on May 15, 2008

... to commence a U.S. pivotal trial to study the effectiveness of its RenalGuard Therapy and RenalGuard System in the prevention of Contrast-Induced nephropathy (CIN). RenalGuard Therapy is designed to reduce the toxic effects that contrast media can have on the kidneys. This therapy is based on the theory ...

Synvista Therapeutics Highlights Newly Published Data Demonstrating the Value of Haptoglobin Genotype Testing In People with Diabetes

... About Synvista Therapeutics Synvista Therapeutics is a biopharmaceutical company developing drugs to treat and prevent cardiovascular disease and nephropathy in people with diabetes. The Company believes it has identified several product candidates that represent novel approaches to some of the largest ...
Nephropathy in Biological Definition

Diabetes mellitus

... and gangrene , sometimes requiring limb amputation , see below nephropathy (due to microangiopathy ) which can lead to renal failure ... control of hypertension plays a pivotal role in preventing both diabetic nephropathy and cardiovascular disease. There is emerging solid evidence that ...

Insulin

... (from proliferative diabetic retinopathy ), toehr vascular damage, nerve damage from diabetic neuropathy , or kidney failure from diabetic nephropathy . These studies have demonstrated beyond doubt that, if it is possible for a patient, so-called intensive insulinotherapy is superior to ...

Kidney

... cholesterol. kidney tumors Wilms tumor Renal cell carcinoma Renal failure (acute and chronic) Glomerulonephritis Diabetic nephropathy Lupus nephritis Dialysis and kidney transplants Generally, one can live fine with just one kidney. If both kidneys do not function ...
Nephropathy in Biological Dictionary

Telomere

... Identification of a specific telomere terminal transferase activity in Tetrahymena extracts" ... Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes. ... Telomere dysfunction provokes regional amplification and deletion ... Negative regulator of telomere ...
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