Narcolepsy

Researcher IDs Narcolepsy as Autoimmune Disease

... say they have determined that the sleep disorder narcolepsy is actually an autoimmune disease. The ... May 3 online issue of Nature Genetics , links narcolepsy to mutations of two genes involved in critical ... that narcoleptics have been found to lack. narcolepsy causes excessive drowsiness, to the point of the ...

Narcolepsy is an autoimmune disorder, Stanford researcher says

... confirming experts' long-held suspicion that narcolepsy is an autoimmune disease. The work, which will ... this story to a close and that we can use narcolepsy as a model for other diseases." narcolepsy affects about one in 2,000 people and is ...

Potential dangers faced by narcoleptics who use nicotine outlined in new abstract

... provides the first description of nicotine use by narcolepsy patients. Because people with narcolepsy can fall asleep suddenly and without warning, ... the excessive sleepiness brought on by their narcolepsy may also complicate any attempt by them to quit ...

Changes in narcoleptics' skin, core body temperatures affect their vigilance and sleepiness

... focused on eight patients who were diagnosed with narcolepsy with cataplexy and suffered from excessive ... when it was lowered, indicating that vigilance in narcolepsy can be altered simply by altering the temperature ... or warming their hands and feet. Patients with narcolepsy lack a specific neurotransmitter in their brains. ...

Lower metabolism, eating behavior possibly explain the cause of overweight in narcolepsy

... Paris, France, focused on 13 patients with narcolepsy and nine healthy controls matched for age, gender ... Only typical narcoleptic patients (those with narcolepsy with clear cataplexy and with suspected ... levels were twice as high in patients with narcolepsy as in controls. Narcoleptic patients had higher ...

Jazz Pharmaceuticals to Present Data From First Phase III Study of Sodium Oxybate in Patients With Fibromyalgia

... approved by the European Medical Evaluation Agency for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the ...

Acupuncture Eases Side Effects of Head, Neck Cancer Treatments

... narcolepsy drug also helped with severe fatigue among patients on chemotherapy ... said. A second study presented Saturday at the meeting found the narcolepsy drug Provigil (modafinil) provided significant relief for patients ...

Addrenex Pharmaceuticals Announces Licensing Agreement With Dream Pharma

... ADHD) and ADX-415 (hypertension and menopausal flushing), Addrenex has two proprietary products in clinical development, ADX-N05 for the treatment of narcolepsy and ADX-117 for procedural sedation. For more information, visit www.addrenex.com ...

Treating sleep disorders in people with traumatic brain injury may not eliminate symptoms

... (35) were free of a sleep disorder, while 23 percent (13) had OSA, 7 percent (4) had periodic limb movements in sleep (PLMS), 5 percent (3) had narcolepsy without cataplexy and 3 percent (2) had post-traumatic hypersomnia. Participants underwent objective evaluation by overnight polysomnography to ...

Narcolepsy Drug Might Be Addictive

... comes as use of stimulant for enhanced mental function is on the increase TUESDAY, March 17 (HealthDay News) -- A drug used to treat narcolepsy is increasingly being taken to sharpen mental skills, but researchers now report troubling evidence that it also harbors the potential for abuse. ...

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Narcolepsy in Medical Technology

Addrenex Pharmaceuticals Expands Product Pipeline by Licensing New Drug to Treat Narcolepsy

... Addrenex Pharmaceuticals. "As an orphan disease, narcolepsy has few treatment options on the market that are ... and commercialize ADX-N05 for the treatment of narcolepsy and other potential indications in the CNS area," ... phase 2 testing of ADX-N05 as a treatment for narcolepsy later this year. The company may also investigate ...

Jazz Pharmaceuticals and UCB Announce Second Phase III Study of Sodium Oxybate in Patients With Fibromyalgia Meets Primary Endpoints

... in Europe , where it is approved by the EMEA for the treatment of narcolepsy with cataplexy in adult patients under a license from Jazz Pharmaceuticals. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the ...

Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia

... by the European Medical Evaluation Agency (EMEA) for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the ...

Jazz Pharmaceuticals, Inc. Completes Enrollment in Second of Two Phase III Clinical Trials of Sodium Oxybate to Treat Fibromyalgia

... U.S. Food and Drug Administration-approved indications. It is also approved by the European Medical Evaluation Agency (EMEA) for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium ...

Jazz Pharmaceuticals and UCB Announce Positive Phase III Results for Sodium Oxybate (JZP-6) in Fibromyalgia

... the U.S. Food and Drug Administration-approved indications. It is also approved by the European Medical Evaluation Agency (EMEA) for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium ...

Narcolepsy in Medical Dictionary

Narcolepsy

... narcolepsy may also be associated with cataplexy, a brief ... between sleep and wake (sleep paralysis ). narcolepsy Related Category: Pathology a sleep disorder ... unwanted episodes of sleep ("sleep attacks"). narcolepsy - A disorder of sleep associated with excessive ...

Amphetamine

... treatment for attention deficit hyperactivity disorder ( ADHD ) and narcolepsy (a sleep disorder). It belongs to the family of drugs called stimulants ... can reduce the likelihood of symptoms related to anxiety disorders . narcolepsy affects over 100,000 people in the United States and appears to have a ...

Hypothyroid

... health care provider depending on the situation. For drowsiness due to narcolepsy , stimulants (like Ritalin ) may be prescribed. Hypothyroid ism ... (underactive ad renal gland ) Heart disorders Sleep apnea or narcolepsy Side effects of medications Cancer Hepatitis B or hepatitis C ......

Hypothyroidism

... health care provider depending on the situation. For drowsiness due to narcolepsy , stimulants (like Ritalin ) may be prescribed. Hypothyroidism may ... (underactive ad renal gland ) Heart disorders Sleep apnea or narcolepsy Side effects of medications Cancer Hepatitis B or hepatitis C ......

Sleep Disorders

... 1610 14th St. NW, Suite 300, Rochester, MN 55901. (507) 287-6006. narcolepsy Network. PO Box 42460, Cincinnati, OH 45242. (973) 276- 0115. You ... , hypersomnia, excessive daytime sleepiness, obstructive sleep apnea , narcolepsy , breathing difficulties during sleep, behavior disturbances during ...

ADHD

... and excessive motor activity. A combination of drugs that is used as a treatment for attention deficit hyperactivity disorder ( ADHD ) and narcolepsy (a sleep disorder). It belongs to the family of drugs called stimulants . Also called dextro amphetamine - amphetamine . addiction ... CAUSES" ...

Attention deficit

... these issues lessen with age. A combination of drugs that is used as a treatment for attention deficit hyperactivity disorder ( ADHD ) and narcolepsy (a sleep disorder). It belongs to the family of drugs called stimulants . Also called dextro amphetamine - amphetamine . addiction ... OCD ...

Hyperactivity Disorder

... ) in patients age 6 and older. A combination of drugs that is used as a treatment for attention deficit hyperactivity disorder ( ADHD ) and narcolepsy (a sleep disorder). It belongs to the family of drugs called stimulants . Also called dextro amphetamine - amphetamine . addiction ... CAUSES" ...

Hyperactivity

... all increase agitation . A combination of drugs that is used as a treatment for attention deficit hyperactivity disorder ( ADHD ) and narcolepsy (a sleep disorder). It belongs to the family of drugs called stimulants . Also called dextro amphetamine - amphetamine . addiction ... ...

Hypercalcemia

... , hypercalcemia , and hypo/hypernatremia are treated by your health care provider depending on the situation. For drowsiness due to narcolepsy , stimulants (like Ritalin ) may be prescribed. Commonly called hypercalcemia , it can be the result of calcium leaching out of the bone, ...

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Narcolepsy in Biological News

Genetic study confirms the immune system's role in narcolepsy

... role in the disorder. "The link between narcolepsy and autoimmunity was proposed decades ago, but ... appears today in Nature Genetics , focused on narcolepsy with cataplexy a sudden loss of muscle tone that ... Mignot, M.D., Ph.D., director of the Center for narcolepsy at Stanford University School of Medicine in Palo ...

What happens when we sleep

... cycle and vital insight into the basis of sleep disorders such as narcolepsy and possibly also other diseases such as depression and Parkinson's. ... turn off during sleep and in their absence, animals and humans experience narcolepsy with cataplexy or sudden loss of mucle tone. However, the role of MCH ...

Natural brain substance blocks weight gain in mice, UT Southwestern researchers discover

... sleep. He found that reduced levels of orexin lead to the sleep disorder narcolepsy in both rodents and humans. Orexin can boost the appetite in the short ... mimics the action of orexin on its receptor, we might be able to treat narcolepsy and other sleep disorders, as well as obesity," Dr. Yanagisawa said. "We ...

New mechanism explains glucose effect on wakefulness

... seeking, hormone release, and metabolic rate, to ensure that the brain always has adequate glucose." Malfunction of orexin neurons can lead to narcolepsy and obesity, and researchers have also found evidence that orexin neurons play a role in learning, reward-seeking, and addiction, wrote the ...

Narcolepsy in Biological Technology

$425 Million Cephalon Civil Settlement and Criminal Fine; In America's Largest

... federal regulations on a grand scale for years by off-label marketing its first three prescription drugs far beyond the cancer pain, epilepsy and narcolepsy specialists for whose patients those drugs had been FDA-approved. Instead, Cephalon focused its national marketing muscle on unapproved uses, ...

FDA Grants Orphan Drug Designation to TREANDA, an Investigational Treatment for Chronic Lymphocytic Leukemia

... for orphan diseases. The company's first product, PROVIGIL(R) (modafinil) Tablets [C-IV], was launched with an orphan drug designation for narcolepsy in 1999. Other Cephalon therapies with orphan drug designation include TRISENOX(R) (arsenic trioxide) injection and CEP-701 (lestaurtinib), which is ...