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Myoglobin in Medical News

JCI table of contents: March 23, 2009

... of these data and discus other ways in which myoglobin might affect tumor progression. TITLE: Prevention of hypoxia by myoglobin expression in human tumor cells promotes ... ACCOMPANYING COMMENTARY TITLE: myoglobin tames tumor growth and spread AUTHOR CONTACT: ...

Pressured proteins: A little pressure in proteomics squeezes 4-hour step into a minute

... of a protein that packs a second, loose molecule inside. When they put myoglobin under 35 kpsi in the absence of trypsin, myoglobin lost its molecular parcel, suggesting that pressure opens up or denatures ...

Biosite Incorporated Issues Voluntary, Nationwide Recall for Cardiac Marker Test

... The product has been recalled due to reports of low recovery of quality control samples containing Creatine Kinase MB (CK-MB), troponin I and myoglobin on the affected lot. Although there have been no reported issues of patient misdiagnosis associated with this lot to date, low recovery may lead to ...

Scientists get first look at how water 'lubricates' proteins

... protein molecule, and see how those movements influence the form and function of the protein. Zhong and his team took laser snapshots of a single myoglobin protein -- the protein that carries oxygen inside muscle tissue -- immersed in water in the laboratory. They were able to measure how fast the water ...

Kidney diseases and their complications, an alarming scenario in the Philippines

... or a traumatic injury, a serious infection, or a toxic reaction to drug. In case of athletes and long runners an acute kidney failure occurs when myoglobin is released due to lack of fluids in the body. Chronic - In this case deterioration takes place gradually over a period of many years. But this is ...

New test for heart attack

... a heart attack is very effective and is to be implemented. They do a blood test for three cardiac enzymes - troponin 1, creatine kinase-MB, and myoglobin - which are released into the circulation by damaged heart tissue. Along with a patient history and an echocardiogram this can rule out a heart ...
Myoglobin in Medical Technology

Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results

... for quantitative determination of CK-MB, myoglobin and troponin I in whole blood and plasma ... Marker System, with separate test kits for CK-MB, myoglobin and troponin I. It is also a quantitative ... to a quantitative result. The tests for myoglobin and troponin T yield results in 8 and 12 minutes ...
Myoglobin in Medical Products

Acute Care Myoglobin TestPak

Description:... The Acute Care myoglobin method is an in vitro diagnostic test for the measurement of myoglobin in heparinized whole blood /plasma. myoglobin measurements can be used as an aid in diagnosing ...
Company:Dade Behring, Inc.

Human Myoglobin Enzyme Immunoassay

Description:... For the quantitative determination of myoglobin concentration in human serum or plasma. The myoglobin ELISA test is based on the principle of a solid ... against a distinct antigenic determinant on the myoglobin molecule. Mouse monoclonal anti-myoglobin ...
Company:Diagnostic Automation, Inc.

Myoglobin - Rapid Test

Description:... The myoglobin Insta Test is an immunochromatography based one step in vitro test. It is ... determination of myoglobin in human serum specimens. The presence of myoglobin in serum at level 100 ng/mL or higher can be detected in 5 ....
Company:Bio-Quant, Inc.

AxSYM Myoglobin

Description:... AxSYM myoglobin is a Microparticle Enzyme Immunoassay (MEIA) for the quantitative determination of myoglobin in human serum or plasma on the AxSYM ....
Company:Abbott Diagnostics

Triage® Cardiac Panel

Description:... The Triage® Cardiac Panel is a fluorescence immunoassay used for the rapid quantitative determination of CK-MB, myoglobin and troponin I in ethylenediaminetetraacetic acid (EDTA) whole blood and plasma specimens. The test is used as an aid in the diagnosis of acute ...
Company:Biosite

Myoglobin Test Modules

Description:... A fluorogenic enzyme-linked immunoassay (ELISA) for the quantitative measurement of myoglobin in human serum or plasma aiding in the diagnosis of acute myocardial infarction (AMI). Features : Dry chemistry-based technology for ease of ....
Company:Dade Behring, Inc.

CARDIAC M Myoglobin

Description:... CARDIAC M myoglobin assay for use with the Cardiac reader analyzer. The Cardiac reader analyzer is a compact, desktop instrument. Other features include: always ready ...
Company:Roche Diagnostics

Innotrac Aio! cardiac marker assays

Description:... on the Innotrac Aio! immunoassay system. Cardiac Troponin I (cTnI) is a marker with very high sensitivity and specificity for myocardial injury (MI). myoglobin appears very soon following AMI. CK-MB (mass) is a traditional marker of cardiac ....
Company:Innotrac Diagnostics

Cardiac Reader System

Features:... for decentralized testing as for central laboratory testing. Choosing the best parameter combination for your patients: Testing troponin T and myoglobin allows rapid diagnosis and risk stratification in patients presenting chest pain and suspicion of myocardial infarction. If you suspect deep vein ...
Company:Roche Diagnostics

Myocardial Infarction - Myoglobin and Troponin Cassette

Description: Rapid Screen Tests are used by hospitals, clinics and the retail consumers to help analyze many human health conditions. The majority of these products are one-step, lateral flow membrane tests, which are offered in strip, cassette, and stick formats. Other panel formats and flow through membrane ...
Company:Biotech Atlantic, Inc.

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Myoglobin in Medical Dictionary

Myoglobin

... myoglobin - serum Definition: Serum myoglobin is a test that measures the amount of myoglobin in the blood . ...

Red urine

... weakness . Labor atory confirmation can come from the demonstration of myoglobin in the blood or urine . Urine of an abnormal color appears ... exercise , as well as burgundy-colo red urine after exercise due to myoglobin (a breakdown product of ... Saliva contains such large amounts of ...

Dementia

... dementia has a much slower onset. Dementia Loss of memory and other higher functions, such as thinking or speech, lasting six months or more. myoglobin uria ... Brain - Dementia Heart - Heart failure , arrhythmias , enlarged heart Kidney s - Kidney failure Nervous system - Numbness, ...

HCG

... menstrual gonad otropin (Pergonal) and human chorionic gonad otropin ( HCG ), are given. Panel tests include: cardiac (CK-MB, troponin I, myoglobin ); quantitative HCG (for pregnancy detection); white and red blood cell count; coagulation; amylase (for pancreatic function). Arch ...

Myopathy

... itself. Alcoholic myopathy , or weakness secondary to breakdown of muscle tissue , is also known as alcoholic rhabdomyolysis or alcoholic myoglobin uria. Males are affected by acute (sudden onset) alcoholic myopathy four times as often as females. Hypertrophic cardio myopathy is another ...

Poison

... , obstetric; paralyssa; paralytic; paralytical; paralytic dementia ; paralytic ectropion ; paralytic ileus ; paralytic mydriasis; paralytic myoglobin uria; paralytic rabies ; paralytic scoliosis ; paralytic shellfish poison ing ... food poison ing or the inability to properly digest ...

Poisoning

... , obstetric; paralyssa; paralytic; paralytical; paralytic dementia ; paralytic ectropion ; paralytic ileus ; paralytic mydriasis; paralytic myoglobin uria; paralytic rabies ; paralytic scoliosis ; paralytic shellfish poisoning ... food poisoning or the inability to properly digest ...

Porphyria

... disorders involving abnormalities in the production of heme pigments (the base material responsible for hemoglobin (red blood cell pigment), myoglobin (reddish muscle cell pigment), ... Porphyria Definition Porphyria is a disorder caused by a change in the amount of porphyrins ...

Rabies

... , obstetric; paralyssa; paralytic; paralytical; paralytic dementia ; paralytic ectropion ; paralytic ileus ; paralytic mydriasis; paralytic myoglobin uria; paralytic rabies ; ... I think it is a bad idea to encourage bats to be around humans because of the risk of rabies . He laughs at my ...

Scoliosis

... , obstetric; paralyssa; paralytic; paralytical; paralytic dementia ; paralytic ectropion ; paralytic ileus ; paralytic mydriasis; paralytic myoglobin uria; paralytic rabies ; paralytic scoliosis ; ... Kaneda anterior spinal/ scoliosis system (KASS)Spinal intervertebral body-fixation ...

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Myoglobin in Biological News

Natural-born divers and the molecular traces of evolution

... is important as divers may contain 10 times more myoglobin in their muscles than terrestrial animals. The ... increase of the amino acid histidine in the myoglobin of strong divers, which may allow the animal to ... they went on to study the molecular sequence of myoglobin in small aquatic mammals such as beavers, ...

Tracking sperm whales and jumbo squid

... their metabolism," Davis added. "Sperm whales, on the other hand, take the oxygen down with them bound to the hemoglobin in their blood and the myoglobin in their muscles, so they don’t have to worry about hypoxia at depth." By spending most of their time in cold, deep waters, he noted, sperm ...

It's in your head: The brain's own globin defends you from shock and stroke

... in the brain's response to oxygen deprivation and plays a protective role against brain damage. Structurally similar to hemoglobin (blood) and myoglobin (skeletal muscle), neuroglobin is found in neurons and is most prevalent in areas of the brain that have adapted to physiological stress, such as ...
Myoglobin in Biological Technology

Acrongenomics on Track to Acquire Molecular Vision

... test using a multi-channel device in less than 5 minutes. Work is underway on developing cardiac markers with preliminary data demonstrating that myoglobin at 100ng/ml can be detected by the system using a fluorescent immunoassay. About Acrongenomics: Acrongenomics Inc. is a publicly traded company ...

Fully Automated Nano-Electrospray Coupled with a Finnigan LCQ Deca XP Plus for Sub-fmol Proteomic Analysis

... human hemoglobin, human macroglobulin, and horse myoglobin were purchased from Sigma-Aldrich, St. Louis, MO, ... The tryptic digest of horse myoglobin was analyzed by nanospray liquid chromatography ... and not optimized for the detection of horse myoglobin digest. The mass range for full mass spectrum was ...
Myoglobin in Biological Products

Mouse Anti-Myoglobin Monoclonal Antibody, Biotin Conjugated, Clone 4E2 from Meridian Life Science, Inc.

Description:... MAb to myoglobin ...
Company:Meridian Life Science, Inc.
Myoglobin in Biological Definition

Muscle

... Slow twitch (type I or "red") - rich in myoglobin (which is red and carries oxygen ), higher ... II) - more anaerobic metabolism (due to less myoglobin and mitochondria) but better at generating more ... not lead to any muscular symptoms at all, the myoglobin thus released may cause acute renal failure . ...

X-ray crystallography

... protein crystal structure was of sperm whale myoglobin , as determined by Max Perutz and Sir John ... in Chemistry . The X-ray diffraction analysis of myoglobin was originally motivated by the observation of myoglobin crystals in dried pools of blood on the decks of ...

Pigment

... 2 External links List of pigments Heme / Porphyrin based Chlorophyll Bilirubin Hemocyanin Hemoglobin myoglobin Light emitting Luciferin Lipochromes Carotenoids Alpha and Beta Carotene Cyanins Anthocyanin Lycopene ...

Protein

... A representation of the 3D structure of myoglobin , showing coloured alpha helices . This protein was the first to have its structure solved by X-ray crystallography by Max Perutz and Sir ...

Secondary structure

... A representation of the 3D structure of the myoglobin protein. alpha helices are shown in colour, and random coil in white, there are no beta sheets in shown. This protein was the first to have ...
Myoglobin in Biological Dictionary

Hemoglobin

... substance decreases the affinity of hemoglobin for oxygen. ... The myoglobin and hemoglobin page provides a description of the structure and function of these two ... myoglobin and hemoglobin are hemeproteins whose ... Hemoglobin in ...
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