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Mouse in Medical News

Finding key to cancer drug Gleevec's limitations

... toward CML are able to resist the drug. "The mouse model we have developed for CML allows us to ... U-M and senior author of the study. Developing a mouse model that closely reproduces the progression of ... testing several two-drug combinations using their mouse model. Imatinib is being combined either with ...

Scientists Track Impact of DNA Damage in the Developing Brain

... DNA strands in an organ system, in this case the mouse brain and nervous system. While the results ... a way to switch off Xrcc1 production in the mouse brain and nervous system as development began. ... system. St. Jude researchers then developed a mouse that carried an Xrcc1 gene outfitted with ...

Scientists Use Non-Embryonic Stem Cells to Create Healthy Mice

... THURSDAY, July 23 (HealthDay News) -- The mouse may be named "Tiny," but what it represents in ... team injected some of the iPS cell lines into mouse embryonic material, a complex technique known as ... resulted in the production of dozens of healthy mouse pups. What's more, the iPS-generated pups were ...

Scientists Use Adult Stem Cells to Create Healthy Mice

... THURSDAY, July 23 (HealthDay News) -- The mouse may be named "Tiny," but what it represents in ... team injected some of the iPS cell lines into mouse embryonic material, a complex technique known as ... resulted in the production of dozens of healthy mouse pups. What's more, the iPS-generated pups were ...

A Phase III Alzheimer's Drug Increases Levels of Beta Amyloid in the Brain - But Still Provides Benefits

... Increases Brain Beta Amyloid in Alzheimer's mouse Models Recent evidence suggests that ... series of experiments in cells and in Alzheimer's mouse models to assess the effects of dimebolin on beta ... Immunotherapy Against Tau Tangles in Alzheimer's mouse Models Immunotherapy (treatment by ...

New technique could sustain cancer patients' fertility

... on earlier efforts by the research team, who grew mouse follicles in culture, induced the eggs they contained to mature, fertilized them with mouse sperm, and implanted them into female mice to ... in culture. The ability to do research on mouse and monkey follicles might lead to advances that ...

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Mouse in Medical Technology

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

... to kill anthrax bacilli. In an in vitro mouse macrophage model, Valortim(R) enhanced the ... and Basu build on this initial information in the mouse model by demonstrating that Valortim(R) can ... Dr. Cross continued, "As is the case with mouse macrophages, our in vitro data suggest that ...

Why Wait for an Anti-Aging Drug? Researchers Interviewed on CBS-TV's 60 MINUTES Discover Longevinex(R) Nutriceutical Matrix Activates 9-Fold More Longevity Genes than Plain Resveratrol

... Longevinex(R) nutriceutical matrix 1711 genes, in mouse heart tissue.* The notion that mega-dose ... of life-prolonging strategies. The mouse has about the same number of genes as humans ... expression of long-term caloric restriction in mouse heart. Barger JL, Kayo T, Pugh TD, Prolla TA, ...

Gene Therapy Corrects Sickle Cell Disease in Laboratory Study

... a harmless virus to insert a corrective gene into mouse blood cells, scientists at St. Jude Children's ... Therapy , the researchers used a strain of mouse with basically the same genetic defect and ... While Persons believes that the mouse experiments will lead to treatments in humans, he ...

Local Research Foundation Achieves Milestone in Fight Against Cancer

... potent anticancer activity against a type of mouse leukemia. The Stehlin Foundation has ... the use of nude mice in cancer research. Nude mouse tests are now the final, non-human studies ... scientists around the world consider the nude mouse one of the 20th century's most ...

Vical Expands Applications of Vaxfectin(R) Adjuvant for Infectious Disease and Cancer Vaccines; 80% to 100% of High-Dose Responders in H5N1 Clinical Trials Still Responding at 6 Months

... Vaxfectin(R)-formulated Cancer Vaccines In a mouse study, a Vaxfectin(R)-formulated vaccine ... 1 clinical trial, the results of nonclinical mouse studies of Vaxfectin(R)-formulated protein-based ... vaccines, and the results of a nonclinical mouse study of a Vaxfectin(R)-formulated TRP-2 ...

Resveratrol Longevity Science Makes Dramatic U-Turn, But Resveratrol Supplements Remain Unchanged

... of long-term caloric restriction in mouse heart. Experimental Gerontology 2008 ... treatment reduces breast tumor growth in a nude mouse model. Translational Oncology 2008 March; ... dietary supplement activity. In the Longevinex(R) mouse study, the Sirtuin1 gene was down-regulated, ...

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Mouse in Medical Products

Coolscope Digital Microscope

Description:... The Coolscope operates with a simple click of the mouse on a monitor display. Direct the mouse cursor to the desired position on the macro image of the slide and the ...
Company:Nikon

Coolscope VS

Description:... The Coolscope operates with a simple click of the mouse on a monitor display. Direct the mouse cursor to the desired position on the macro image of the slide and the ...
Company:Nikon

Coolscope

Description:... The Coolscope operates with a simple click of the mouse on a monitor display. Direct the mouse cursor to the desired position on the macro image of the slide and the ...
Company:Nikon

FDP PLASMA

Description:... Determination of FDP in Plasma by Latex Agglutination, 60 tests.Microlatex particles coated with mouse monoclonal anti-human FDP ....
Company:Diagnostica Stago, Inc.

STA LIATEST D-DI

Description:... Immuno-turbidimetric Assay of D-Dimer by STA© Analyzers. Microlatex particles coated with two different mouse monoclonal anti-human D-Dimer ....
Company:Diagnostica Stago, Inc.

Electronic Clinical Record

Description:... you by reducing your time and effort on extraneous tasks and liberating you to concentrate on the clients quality of care. A simple click of the mouse completes a chart audit and shows you everything you need to do, all in one ....
Company:Anasazi Software

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Mouse in Medical Definition

Autoimmune regulator

... A gene knockout of the murine homolog Aire has created a transgenic mouse model to study the mechanism of disease in human patients. [2] Research on the knockout mouse has demonstrated that Aire functions through initiating the transcription ...

Depolarization-induced suppression of inhibition

... Marzo V. (2006) Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience. Apr 5; In Press. Hajos N, Freund TF. (2002) Pharmacological separation of cannabinoid sensitive receptors on hippocampal ...
Mouse in Medical Dictionary

Borrelia

... In the United States, Borrelia burgdorferi is borne by ticks of several species in the genus Ixodes, which usually feed on the white-footed mouse and deer (and are often called deer ticks ). Lyme disease is a progressive, systemic illness that is caused by bacteria ( Borrelia ...

Bronchi

... specific for the bronchi al epithelium , and are analyzing additional candida tes. Our goal is to use such cell type-specific genes to buiTd mouse models of various human lung cancer s. ...

Epithelium

... specific for the bronchi al epithelium , and are analyzing additional candida tes. Our goal is to use such cell type-specific genes to buiTd mouse models of various human lung cancer s. ...

Host

... host . The natural host of Rickettsia akari is the house mouse. Humans are acci dental hosts who become infected when bitten by an infected mouse mite. The disease was first recognized in New York City. Fuzeon (enfuvirtide); formerly designated T-20 First of a new class of anti - HIV ...

Mammary

... correlation between high levels of fat and mammary carcinoma s. Their research has focused on a virus called HHMMTV (human homologue of mouse mammary tumour virus ), a form of MMTV (mouse mammary tumour virus ), which causes more than 95 per cent of breast cancer in mice. They ...

Rickettsia

... lpox . The natural host of Rickettsia akari is the house mouse. Humans are acci dental hosts who become infected when bitten by an infected mouse mite. Streptococcal and staphylococcal bacteria are the most common causes of lymphadenitis , although virus es, protozoa, rickettsia e, ...

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Mouse in Biological News

Protein handlers should be effective treatment target for cancer and Alzheimer's

... a viral immunologist, have developed 20 mouse models missing different molecular chaperones or ... chaperones. For contrast, they also have a mouse that over expresses heat shock factor 1, or Hsf1, ... breast cancers. By comparing the resulting mouse to one that just over expresses Her2/Neu, they ...

Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

... cancer. Their studies were performed in mouse cancer models and in human cell cultures. ... and then proteins. Studies in both cells and a mouse model for cancer showed that they could promote ... act as a "first hit" that makes the inversion on mouse chromosome 6, which contains the DLX5 gene, more ...

Scientists track impact of DNA damage in the developing brain

... DNA strands in an organ system, in this case the mouse brain and nervous system. While the results ... a way to switch off Xrcc1 production in the mouse brain and nervous system as development began. ... system. St. Jude researchers then developed a mouse that carried an Xrcc1 gene outfitted with ...

Scientists closer to making implantable bone material, thanks to new research

... materials that were grown from bone cells from mouse skull and mouse bone marrow stem cells successfully mimicked many ... found that the 'bone-like' material grown from mouse embryonic stem cells was much less stiff and less ...

Scientists link immune system's natural killer cells to infant liver disease

... led the research team to experiment with a mouse model of biliary atresia. In the mouse experiments, the scientists used a rotavirus ... cells were the most abundant cells populating the mouse livers and bile ducts at the time of obstruction. ...

Children's Hospital of Pittsburgh of UPMC scientists identify enzyme important in aging

... according to researchers studying an "anti-aging" mouse model that lives longer than a typical mouse. ... of Pittsburgh of UPMC, reports that the novel mouse model has a thymus that remains intact throughout ... throughout life," said Dr. de Vallejo. The mouse model that Dr. de Vallejo's team studied was ...

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Mouse in Biological Technology

ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA

... is a departure from other methods for determining mouse HMW adiponectin and was first introduced in a ... oligomers using protease pretreatment, and the mouse HMW Adiponectin ELISA kit reflects a similar ... for its consistency and quality. The new mouse HMW and total adiponectin ELISA has been held to ...

febit First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment

... on the market covering the newly published whole mouse genome. The biochip from febit enables up-to-date ... Heidelberg (Germany) and customer of febit's new mouse biochip, said: "It will be helpful and an advance ... of interest, as demonstrated by the updated mouse genome. This accelerated development will ...

Assessment of safety and efficacy of human embryonic stem cell therapy

... was carried out in the NIH III immune deficient mouse model. Long-term data (spanning the life of the ... chosen for a GLP safety study using the NIH III mouse model, an immune deficient animal model. ... we also showed that vision can be rescued in a mouse model of Stargardt's disease, which is a form of ...

ZyGEM Releases Application Note Showing its DNA Extraction Kits Rapidly Produce High Yields of Quality DNA

... Commercial Kits-- -- Samples Prepared from mouse Tails Using prepGEM(TM) Yielded Over 34 Times the ... DNA and determining precise genotypes from mouse tail samples. Researchers performed extractions ... DNA. "This new application note focusing on mouse genotyping demonstrates that our prep GEM(TM) ...

GeneCopoeia Introduces Genome-Wide MicroRNA (miRNA) Functional Analysis Tools

... cover all known miRNAs for human (750), mouse (450), and rat (270). These lentiviral vector ... UTR) expression clones cover genome-wide human, mouse and rat genes. These expression ready constructs ... number of full-sequence-verified human and mouse full length protein coding ORF cDNA clones , ...

Mouse study reveals genetic component of empathy

... cage with something negative simply by hearing a mouse in that cage respond with squeaks of distress. A genetically different mouse strain with fewer social tendencies did not learn ... Panksepp says. In the experiments, one mouse observed as ...

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Mouse in Biological Products

DETACHaBEAD Mouse CD4 from Dynal Biotech

Description:... The product contains 5 ml of DETACHaBEAD mouse CD4, polyclonal Sheep anti-Mouse Fab to release mouse CD4+ T cells from Dynabeads mouse CD4 (L3T4). Detach positively isolated mosue ...
Company:Dynal Biotech

Human Neural Stem Cell Functional Identification Kit from R&D Systems

Description:... lineages. An antibody panel consisting of mouse anti-human Nestin, mouse anti-human Glial Fibrillary Acidic Protein (GFAP), mouse anti-Neuron-specific beta-III Tubulin, ...
Company:R&D Systems

Rabbit Anti-ZO-1 (N-term) Monoclonal Antibody,, Clone ZMD.437 from Invitrogen

Description:... derived from the N-terminal region of human dog mouse and rat ZO-1. Specificity: Specific for the ... ~225 kDa ZO-1 protein. Reactivity: Human Dog Rat mouse (positive controls: MDCK-II A431 Caco-2 Rat-1 NRK-52E cells frozen mouse liver heart blood vessel and brain mossy fiber ...
Company:Invitrogen

Rabbit Anti-Mouse Junctophilin-1 (Mid) Monoclonal Antibody,, Clone ZMD.471 from Invitrogen

Description:... peptide derived from the internal region of the mouse junctophilin-1. Specificity: Specific for the junctophilin-1 protein. Reactivity: mouse (positive controls: mouse brain and skeletal muscle homogenates ...
Company:Invitrogen

Rabbit Anti-PKCZeta (C-term) Monoclonal Antibody,, Clone ZMD.330 from Invitrogen

Description:... the C-terminal region catalytic domain of rat and mouse protein kinase C zeta isoform (PKCzeta). Specificity: Reacts with the rat and mouse PKCzeta protein. Recognizes PKCzeta and PKMzeta ... not cross-react with PKCiota/lambda. Reactivity: mouse Rat (positive ...
Company:Invitrogen

Rabbit Anti-Human Connexin 36 Monoclonal Antibody,, Clone ZMD.257 from Invitrogen

Description:... Cat. No. 51-6300. Specificity: Reacts with mouse Connexin 36. Reactivity: mouse (positive control: mouse Connexin 36-transfected HeLa cell ...
Company:Invitrogen

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Mouse in Biological Definition

Photosynthesis

... it ran out of wax. He further discovered that a mouse could similarly "injure" air. He then showed ... air that had been "injured" by the candle and the mouse could be restored by a plant. In 1778 , Jan ... on the plant that could cause it to rescue a mouse in a matter of hours. In 1796 , Jean Senebier ...

Monoclonal antibody

... ) is injected into a vertebrate such as a mouse or a human , some of the immune system 's ... of producing monoclonal antibodies yields mouse antibodies, and these are rejected by the human ... that encodes the binding portion of monoclonal mouse antibodies and merges it with human antibody ...

Photosynthesis

... it ran out of wax. He further discovered that a mouse could similarly "injure" air. He then showed ... air that had been "injured" by the candle and the mouse could be restored by a plant. In 1778 , Jan ... on the plant that could cause it to rescue a mouse in a matter of hours. In 1796 , Jean Senebier ...

Apoptosis

... without eliciting an inflammatory response [5] , [6] . In studies on mouse embryos lacking PS receptors conducted by Ming O. Li and colleagues [7] , ... after SMAC (Second Mitochondria-derived Activator of Caspases, or its mouse homolog, called DIABLO), a mitochondrial protein, is released into the ...

BLAST

... For example, following the discovery of a previously unknown gene in the mouse , a scientist typically will perform a BLAST search of the human genome ... gene; BLAST will identify sequences in the human genome that resemble the mouse gene based on similarity of sequence. BLAST is one of the most widely ...

Down syndrome

... years ago, Johns Hopkins scientists created a genetically engineered mouse called Ts65Dn (segmental trisomy 16 mouse) as an excellent model for studying the Down syndrome. Ts65Dn mouse has genes on chromosomes 16 that are very similar to the human chromosome ...

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Mouse in Biological Dictionary

Transgenic mouse

... ... Explanations about transgenic mouse and the history of biological experimentations ... mice - TOP 100 BIOLOGY SITES ... Trangenic mouse Facility - Home Page ... The UC Irvine Transgenic mouse Facility is a core facility that provides ... ...

Synteny

... Steve Fischer at the ... ... the genomes of mouse and humans - synteny ... 1. Synteny between the mouse and human genomes ... function, but it is not ... on ... Synteny map. Human NCBI build 31 vs. mouse NCBI build 30. Conserved ... ...

Mouse

... A mouse (plural mice) is a small mammal belonging to the order of rodents. The best known mouse species is the common house mouse (Mus musculus). It is also a popular pet. The ...

His tag

... #2365. pathway. more ... 2276 Myc- Tag (9B11) mouse mAb. 2372 β-Gal (14B7) mouse mAb. 2396 MBP (8G1) mouse mAb ... Product Pathways - Related Products. ...

Gene knockout

... function. Researchers ... A knockout mouse is a genetically engineered mouse in which one or more genes have been turned off ... Molecular ... ... example, the p53 knockout mouse is named after the p53 gene , which codes for a ...

Dysgenic

... have been studied in animals such as the mouse and the fruit fly. ... For an environment ... What is dysgenic cross? Why would a dysgenic mouse die shortly ... "David Starr Jordan on the ... from the homozygous dysgenic (mdg/mdg) mouse cell line GLT ... Differentiated GLT dysgenic ...

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(Date:7/25/2014)... engineering at the University of Houston, has written ... organ development., "Introduction to Tissue Engineering: Applications and ... the field of artificial organ development. Metin Akay, ... UH, served as a series editor on the ... published books on the subject of growing artificial ...
(Date:7/25/2014)... of Adelaide has opened the way for the development of ... In Australia, annual barley production is second only to wheat ... of the most important diseases of barley. , Senior Research ... of special growths on the cell walls of barley plants ... , The research, by the ARC Centre of Excellence in ...
(Date:7/25/2014)... a complex congenital central nervous system disease that ... neural tubes during the embryonic phase. Many patients ... incontinence and neurocognitive retardation. Such problems decrease the ... Researchers at Ankara Physical Medicine and Rehabilitation Education ... in children with SB, using the Pediatric Evaluation ...
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