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Monocyte in Medical News

Researchers identify how binge drinking may drive heart disease

... buildup. At this point, adhesion molecules on the monocyte surfaces unfold and grab onto key proteins on the ... like anchors that snag the vessel wall. Once the monocyte swings close to the wall on its tether, it can ... current study found that acetaldehyde stimulated monocyte adhesion through its effect on three important ...

Biomarker May Signal HIV Progression

... researchers found an increase in the CD163+/CD16+ monocyte subset may coincide with the advancement of human ... all we know is what the correlations are." A monocyte is a specific white blood cell, a part of the ... with detectable virus had an increase of this monocyte subset that correlated with the amount of virus ...

Expansion of monocyte subset could serve as a biomarker for HIV progressions

... An increase in the CD163+/CD16+ monocyte subset could be a biomarker for the progression ... Retroviruses (www.liebertonline.com/aid). A monocyte is a specific white blood cell, a part of the ... were investigating alterations in this monocyte subset in patients with HIV infection. As part ...

UCLA scientists identify how immune cells may help predict Alzheimer's risk

... researchers then measured the amount of amyloid beta ingested by the immune cells by assessing how much fluorescence was being emitted from each monocyte cell. The 18 Alzheimer's disease patients in the study showed the least uptake of amyloid beta; the healthy control group, which consisted of 14 ...

Study in Nature Medicine establishes major new treatment target in diseased arteries

... mice, with the opposite being true for mice with extra CypA. Angiotensin II treatment also dramatically increased expression of cytokines (e.g. monocyte chemoattractant protein 1(MCP-1)), unless CypA was missing. "Our lab has been studying CypA since the early 1990s," Berk said. "We had to ...

Ophthalmology highlights Jan. 2009

... 8 diabetic patients without retinopathy. Vascular endothelial growth factor (VEGF), intercellular adhesion molecule (ICAM)-1, interleukin (IL)-6, monocyte chemotactic protein (MCP)-1 and the anti-inflammatory pigment epithelium-derived factor (PEDF) were selected because earlier research had linked them ...

Chemical liberated by leaky gut may allow HIV to infect the brain, Einstein scientists find

... of monocytesHIV/GFP-producing monocytes from the HIV/GFP-TG mice, and monocytes from the GFP-TG mice producing GFP aloneand injected each type of monocyte into control mice. Four days later, the researchers examined the brains of the injected mice to see whether monocytes from the bloodstream had ...

An emerging candidate for protecting patients from liver injury after abdomen surgery

... and the activity of hepatic enzymes, including LDH, ALT, and AST, and the concentration of pro-inflammatory mediators such as TNF-, IL-6 and monocyte chemotactic protein-1 (MCP-1). After careful evaluation, the researchers concluded R1 prevents I/R-induced hepatic microcirculation disturbance and ...

Evidence links anemia drugs with leukemic transformation in patients with primary myelofibrosis

... were documented. Other factors appeared to contribute to the development of leukemia, including anemia, leukocytosis and peripheral blood monocyte count greater than or equal to 1x109/L (both are measures of elevated white blood cells), hypercatabolic symptoms (results of excess metabolism), a ...

IDM Pharma Announces Data Presentation From Mifamurtide (L-MTP-PE) Compassionate Use Program

... IV over 1 hour) was administered twice a week for 12 weeks followed by once a week for 24 weeks in combination with aerosol recombinant granulocyte monocyte colony stimulating factor (GM-CSF), an immune stimulating agent. In addition, some patients in the program were also treated with gemcitabine (n=2) ...
Monocyte in Medical Technology

VisEn Molecular Imaging Technology Enables Key Insights Into Newly Discovered Biologic Pathway Published in SCIENCE

... The newly reported biologic pathway relates to monocyte deployment from the spleen to inflammatory sites, ... reservoir of monocytes, and demonstrate the monocyte deployment to inflammatory sites in vivo . In ... the heart to identify and quantify biomarkers of monocyte activity in vivo . These results enabled an ...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

... of Medicine and Pharmacy and colleagues showed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human immature dendritic cells from blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody ...

Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting

... increase in the anti-tTG titer in the placebo (control) group, which was prevented in the group on larazotide acetate. -- Other trends in specific monocyte populations induced by gluten challenge were also prevented to varying extents by larazotide acetate. The second presentation, "Larazotide Acetate, ...

IDM Pharma Announces Updated Data From Mifamurtide (L-MTP-PE) Compassionate Access Program

... by once a week for 24 weeks. In addition, some patients in the program were also treated with other agents including aerosol recombinant granulocyte monocyte colony stimulating factor (GM-CSF) an immune stimulating agent (n=20), ifosfamide (n=4), and/or gemcitabine (n=2). Results to date are as ...

Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Dose Escalation Trial with Tovaxin for Multiple Sclerosis

... license for adult multipotent stem cells derived from mononuclear cells of peripheral blood. The technology allows large quantities of monocyte derived stem cells to be produced efficiently for use in autologous therapy, thus circumventing the threat of rejection. The Company is in ...

Opexa Presents Tovaxin Research at Federation of Clinical Immunology Societies Annual Meeting

... worldwide license for adult multipotent stem cells derived from mononuclear cells of peripheral blood. The technology allows large quantities of monocyte derived stem cells to be produced efficiently for use in autologous therapy, thus circumventing the threat of rejection. The Company is ...

Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Extension Trial with Tovaxin for Multiple Sclerosis

... license for adult multipotent stem cells derived from mononuclear cells of peripheral blood. The technology allows large quantities of monocyte derived stem cells to be produced efficiently for use in autologous therapy, thus circumventing the threat of rejection. The Company is in ...

Opexa Advances Monocyte Derived Islet Technology to Proof of Principle in stz-induced NOD/SCID Mice

... worldwide license for adult multipotent stem cells derived from mononuclear cells of peripheral blood. The technology allows large quantities of monocyte derived stem cells to be produced efficiently for use in autologous therapy, thus circumventing the threat of rejection. The Company is ...
Monocyte in Medical Products

Giemsa Stain

Description:... bone marrow. Erythrocytes stain pink to buff with platelets exhibiting a very light, pale pink. Leukocyte nuclear chromatin stains magenta-purple, monocyte cytoplasm stains the classical "ground glass" blue and lymphocyte cytoplasm stains clear, sky ....
Company:Richard-Allan Scientific
Monocyte in Medical Dictionary

Leukocytes

... system . Neutrophil s, lymphocyte s, and monocyte s are all leukocytes . leukocytes White ... and T-cells. Mononuclear Leukocytes : monocyte s Lymphocyte s White blood cells are the ... Types of white blood cells: lymphocyte s, monocyte s, eosinophil s, basophils, neutrophil s ( ...

Lymphocyte

... leukocyte subgroup (like macrophage / monocyte s ). Lymphocyte s are white blood cells ... s produce immune cells (such as lymphocyte s, monocyte s, and plasma cells). They also filter the ... of pus , which also destroys bacteria , and monocyte s and lymphocyte s which also are important for ...

Macrophage

... A large white blood cell , derived from monocyte s (a subclass of Mononuclear Leukocytes ). ... ism. HIV can infect and kill macrophage s. monocyte ... Alternative Names: Macrophage Receive ... system are also liable to HIV attack. Called monocyte s and macrophage s, these cells may serve to ...

Monocyte

... monocyte Multi media from HONselect: monocyte s monocyte A white blood cell which can ingest dead or ...

Microorganism

... the host defense system is to eliminate invading microorganism s. monocyte s recognize a variety of microorganism s, especially gram-negative bacteria . Activated monocyte s turn into macrophage s that can engulf and destroy microorganism s and ...

Neutrophil

... s), T-type lymphocyte s (T cells), B-type lymphocyte s (B cells), monocyte s, ... A colon y-stimulating factor that stimulates the production of ... are the main constituent of pus , which also destroys bacteria , and monocyte s and lymphocyte s which also are important for the immune system . ...

Phagocyte

... a virus or other foreign matter by phagocyte s. See Macrophage ; monocyte . phagocyte An immune system cell that can surround and kill ... lymphocyte , lymph ocytosis, macrocyte, megakaryocyte, melanocyte, monocyte , oocyte, pancytopenia, phagocyte , ... ...

Eosinophil

... eosinophil ; ... A machine generated percentage of the different types of white blood cells, usually split into granulocyte s, lymphocyte s, monocyte s, eosinophil s, and basophils. Red cell count ( RBC ). The number of red blood cells in a volume of blood . The earliest finding is within ...

Gamma

... blood protein s; ... There are three main classes of interferon: alpha , beta , and gamma . IFN alpha is produced by virus -infected monocyte s and lymphocyte s . IFNbeta is produced by virus -infected fibroflasts (and some other cell types). Within the scanner are rings of ...

Granulocyte

... infection . A machine generated percentage of the different types of white blood cells, usually split into granulocyte s, lymphocyte s, monocyte s, eosinophil s, and basophils. Red cell count ( RBC ). The number of red blood cells in a volume of blood . granulocyte colon ...

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Monocyte in Biological News

Melanoma vaccine strategy shows promise in laboratory experiments

... T cells to attack the melanoma cells. Another type of immune cell called a monocyte was used to present the peptide, BRAFV600E, to the killer T cells to ... peptide would trigger the killer T cells even more effectively than the monocyte cells used in the current study. Indeed, such prepared dendritic cells ...

Source of crucial immune cell in the skin discovered

... beads in mice in a group of immune cells known as monocytes. They then followed the cells to observe their fate. They found that a specific type of monocyte know as Gr-1 homes to inflamed skin, proliferates, and then differentiates to form Langerhans cells. They also found that a protein, called colony ...
Monocyte in Biological Technology

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... and Pharmacy and colleagues at the 12th NFID meeting in Baltimore showed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... Ohio Universities Colleges of Medicine and Pharmacy and colleagues showed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody ...

MedImmune Presents Data Highlighting its Progressive Inflammatory Disease Portfolio at the 72nd Annual Meeting of the American College of Rheumatology

... M.Sc., Sunday, October 26 from 9:00 a.m. - 11:00 a.m. in Hall A, Abstract: 46 -- Internalization of the antibody (CAM-3001) following monocyte cell surface binding to the GM-CSFR alpha chain - Brandon Higgs, Ph.D., Sunday, October 26 from 9:00 a.m. - 11:00 a.m. in Hall A, Abstract: ...

Cellix Ltd. Launches VenaEC Biochip for Flow-based Cell-adhesion Assays

... on the VenaEC Biochip. Validated examples to date include a Human Coronary Artery Endothelial Cell (HCAEC) monolayer for the investigation of monocyte adhesion for cardiovascular diseases and a Human Microvascular Endothelial Cell (HMVEC) monolayer for the investigation of eosinophil adhesion for ...

Laser Capture Microdissection (LCM) for the Analysis of Macrophage Gene Expression from Atherosclerotic Lesions

... transcript levels of the following genes were measured: vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule1 (ICAM-1), and monocyte chemoattractant1(MCP-1) (see Table I for gene primer sequences). As shown in Table II, LPS stimulation increased the expression of the Nuclear ...

HL-60

... 11/1999 Cell line HL-60, human monocyte like cells (suspension cell line) Transfection with Plasmid pEGFP-N1 (in bidistilled H 2 O) ...

Eppendorf Multiporator Transfection Protocols for Eukaryotic Cells

... line 721.82: EBV transfected B-cell line HeLa: Cervix epitheloid carcinoma HL-60: monocyte like cells Jurkat: T-cell line T98G: Glioblastoma t-HUVEC: Transformed ...

Eppendorf Multiporator Transfection Protocols for Eukaryotic Cells

... line 721.82: EBV transfected B-cell line HeLa: Cervix epitheloid carcinoma HL-60: monocyte like cells Jurkat: T-cell line T98G: Glioblastoma t-HUVEC: Transformed ...

Enzyme Immunoassay for Studying Intracellular Levels of cAMP

... maximal stimulation in the cell line of interest. In addition to Jurkat cells, AC toxin has also been shown to elevate cAMP in monocyte macrophages, 10 polymorphonuclear leukocytes and alveolar macrophages, 11 natural killer cells 12 and HL-60 promyelocytic ...
Monocyte in Biological Products

Canine CCL2 (JE; MCP-1) ELISA development Kit, DuoSet from R&D Systems

Description:... DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant canine monocyte Chemotactic Protein 1 (MCP-1) in cell culture supernates and serum.1 Each kit contains sufficient materials to run ELISAs on approximately fifteen ...
Company:R&D Systems

Mouse Anti-Human DEP-1 / CD148 Monoclonal Antibody, Fluorescein Conjugated, Clone 143-41 from R&D Systems

Description:... Human DEP-1/CD148 Fluorescein MAb (Clone 143-41) Protein Family: Granulocyte Markers, monocyte Markers, Phosphatases & Regulators, Other Dendritic Cell ...
Company:R&D Systems

UCB Monocyte Cell Chip-IHC from 3H Biomedical AB

Description: Umbilical cord blood CD14+ Monocytes, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood Monocytes, B Cells and NK ...
Company:3H Biomedical AB
Monocyte in Biological Dictionary

Monocytes

... monocyte is a type of white blood cell, part of the human body's immune system. Monocytes have two main functions in the immune system: (1) replenish ...

Beta sheet

... ... Dr Chromo's School: the beta -pleated sheet ... Home of protein beta - sheet tools ... The featured beta - sheet is from the monocyte chemoattractant protein 1 (MCP-1) (PDB code 1DOK) ... ... beta - sheet tools ... These beta - sheets can be encoded in graphs, where ...
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(Date:9/23/2014)... A 2014 study supported by the ... has found that rising temperatures and hotter ... children developing kidney stones. Researchers based their findings ... U.S. cities, including Dallas, Atlanta, Philadelphia, Chicago and Los ... for kidney stones within a relatively short span – ...
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(Date:9/23/2014)... from the University of Toronto, directed by Drs. ... in normal vestibular nerves and vestibular schwannomas (VSs). ... negligible difference between VSs that sporadically occur and ... a genetic disorder; and 2) the overexpressed PI3K/AKT/mTOR ... excellent therapeutic target. Detailed findings of this study ...
(Date:9/23/2014)... PA (PRWEB) September 23, 2014 Rinovum ... home-use conception assistance device on the market cleared by ... in stores and online at http://www.storkotc.com . , ... dream of having a baby is delayed by infertility1 ... first step to optimize their chances to conceive. ...
(Date:9/23/2014)... 2014 Ale Gicqueau, President and Chairman ... Data Visualization for Clinical Trials at the upcoming ... Francisco on Friday, September 26, 2014. , PhUSE ... its inception, PhUSE has expanded from its roots as ... platform for the discussion of topics encompassing the work ...
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(Date:9/21/2014)... autism are significantly less likely to report taking iron ... of children who are developing normally, a study by ... , Low iron intake was associated with a five-fold ... mother was 35 or older at the time of ... conditions such as obesity hypertension or diabetes. , The ...
(Date:9/21/2014)... MA -- In recent years, new strains of bacteria ... Each year, these superbugs, including drug-resistant forms of tuberculosis ... and kill at least 23,000. Despite the urgent need ... classes of antibiotics in the past decade. , MIT ... these superbugs. Using a gene-editing system that can disable ...
(Date:9/19/2014)... Jimmy Durante of dinosaurs a newly discovered ... new dinosaur, named Rhinorex condrupus by ... Young University, lived in what is now Utah ... Cretaceous period. , Rhinorex, which translates roughly into ... relative of other Cretaceous hadrosaurs like Parasaurolophus and ...
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