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Monoclonal in Medical News

Micromet, Inc. Reports Second Quarter 2009 Financial Results

... from the currently marketed EGFR-specific monoclonal antibodies Erbitux(R) (cetuximab) and Vectibix(R) ... the resistance of mutated tumor cells to those monoclonal antibodies. Micromet also presented data at the ... 2009 on a phase 1b combination study of its human monoclonal antibody adecatumumab with docetaxel in patients ...

QuikByte Software, Inc. and Sorrento Therapeutics, Inc. Announce Merger Agreement

... technology for the generation of fully human monoclonal antibodies, and QuikByte Software, Inc. (OTC ... technology for the generation of fully human monoclonal antibodies." Glenn L. Halpryn stated "We ... platform for the generation of fully human monoclonal antibodies based on its proprietary technology. ...

Peregrine Pharmaceuticals Completes Planned Patient Enrollment in Bavituximab Phase I Cancer Trial

... follow-up are continuing. Bavituximab is a monoclonal antibody with a unique mechanism that enables the ... for anti-cancer treatments. Bavituximab is a monoclonal antibody that binds specifically to these ... company with a portfolio of innovative monoclonal antibodies in clinical trials for the treatment ...

Phase 1 Study Initiated with Micromet Anti-GM-CS Human Antibody MT203

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

New Therapies, Including Novel Biologic Agents from Elan/Wyeth and Eli Lilly, Will Drive Robust 11 Percent Annual Growth In the Alzheimer's Disease Market

... that the launch and uptake of new anti-amyloid monoclonal antibodies, most notably Elan/Wyeth's ... disease market in 2018. While these two monoclonal antibodies are expected to offer superior ... and commercial promise are the anti-beta amyloid monoclonal therapies such as bapineuzumab and solanezumab, ...

Elusys Therapeutics and Lonza Enter Into Manufacturing Agreement

... for the production of Anthim(TM), a therapeutic monoclonal antibody in late stage development for the ... experience in large-scale manufacturing of monoclonal antibodies and a well-established reputation with ... is a high-affinity, humanized and deimmunized monoclonal antibody that targets the protective antigen of ...

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Monoclonal in Medical Technology

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... Sigma-Aldrich Corporation (Nasdaq: SIAL ), Open monoclonal Technology, Inc. (OMT) and INSERM today announced ... . About Open monoclonal Technology, Inc.: Open monoclonal Technology, Inc. ("OMT") is a private ...

Tolerx Presents Data at 69th Scientific Sessions of the American Diabetes Association

... with a surrogate of its Phase 3 anti-CD3 monoclonal antibody, otelixizumab, at the 69th Scientific ... of modified dosing regimens of the anti-CD3 monoclonal antibody in a commonly used non-obese diabetic ... result demonstrates that lower doses of anti-CD3 monoclonal antibody, causing partial TCR modulation, are ...

Micromet's Blinatumomab Achieves Primary Endpoint in Phase 2 Study with Acute Lymphoblastic Leukemia Patients

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet Presents Update on Blinatumomab's Response Rate and Duration in a Phase 1 Study in Non-Hodgkin's Lymphoma Patients

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Peregrine Pharmaceuticals Highlights Promising Early Data From Its Three Phase II Bavituximab Cancer Trials

... three separate cancer trials. Bavituximab is a monoclonal antibody with a unique mechanism that allows the ... for anti-cancer treatments. Bavituximab is a monoclonal antibody that binds specifically to these ... company with a portfolio of innovative monoclonal antibodies in clinical trials for the treatment ...

PharmAthene Submits Proposal to BARDA in Response to Broad Agency Announcement for Advanced Research and Development for Valortim(R)

... to further develop Valortim(R), a fully human monoclonal antibody, for the prevention and treatment of ... About Valortim(R) Valortim(R) is a fully human monoclonal antibody generated by Medarex, Inc's UltiMAb(R) ... vaccine Valortim(R) - a fully human monoclonal antibody for the prevention and treatment of ...

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Monoclonal in Medical Products

TPO (Ab) RIA Thyroid Function 014-HD-90.1 Thyroid Peroxidase

Description:... assay is indirectly labelled with a monoclonal iodine-125 antibody to prevent the denaturation of the sensitive antigen. In connection with the monoclonal antibody on the solid phase this method ... During incubation, solid-phase monoclonal anti-TPO antibodies and enzymatic active ...
Company:ALPCO Diagnostics

Pathfinder Respiratory Syncytial Virus EIA

Description:... system, that can use nasal washings or aspirates. It uses polyclonal and monoclonal antibodies to detect RSV directly in patient specimens. This assay combines the specificity and reproducibility of monoclonal antibodies with the speed and efficiency of an EIA. Qualitative results ...
Company:Bio-Rad Laboratories

KRONUS OptiQuant™ Thyroglobulin (OQTg) Kit

Description:... or patient specimens, along with I125 anti-human thyroglobulin (mouse monoclonal IgG subclass 2ak), are allowed to incubate overnight with the primary antiserum coated on the tubes (mouse monoclonal IgG subclass 1k), during which time the Tg present is sandwiched between ...
Company:KRONUS

Human Myoglobin Enzyme Immunoassay

Description:... enzyme-linked immunosorbent assay. The assay system utilizes a unique monoclonal antibody directed against a distinct antigenic determinant on the myoglobin molecule. Mouse monoclonal anti-myoglobin antibody is used for solid phase immobilization (on the ...
Company:Diagnostic Automation, Inc.

Insulin Jumbo EIA Diabetes and Obesity Markers 008-10-1113-99

Description:... immunoassay. It is based on the direct sandwich technique in which two monoclonal antibodies are directed against separate antigenic determinants on the ... immunoassay. It is based on the direct sandwich technique in which two monoclonal antibodies are directed against separate antigenic determinants on the ...
Company:ALPCO Diagnostics

Giardia lamblia II EIA

Description:... We offer a complete line of enteric disease products bringing laboratorians state-of-the-art monoclonal and monoclonal/polyclonal antibody-based ELISA tests for the detection of enteric pathogens in fecal specimens. Our line includes products for ...
Company:Inverness Medical Innovations

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Monoclonal in Medical Definition

Medical procedure

... therapy Insulin potentiation therapy Low-dose chemotherapy monoclonal antibody therapy Photodynamic therapy Radiation therapy ... Negative Pressure Wound Therapy Nicotine replacement therapy monoclonal antibody therapy Oral rehydration therapy Insulin potentiation ...

Central tolerance

... • Inflammation • Complement system ( Classical , Alternative , Lectin , Anaphylatoxins ) • Cytokines • White blood cells • Antibody ( monoclonal antibodies , Autoantibody ) • Antigen • APC • MHC Immunity • Autoimmunity • Tolerance ( Central ) • Immunodeficiency ...

Proteopathy

... Familial amyloidotic neuropathy, Senile systemic amyloidosis Transthyretin AL (light chain) amyloidosis ( primary systemic amyloidosis ) monoclonal immunoglobulin light chains AH (heavy chain) amyloidosis Immunoglobulin heavy chains AA (secondary) amyloidosis Amyloid A protein ...
Monoclonal in Medical Dictionary

Antibody

... antibody test? Kelly/ New York ... monoclonal antibody therapy is a cancer treatment that ... Dr Rob Hicks in December 2005. Disclaimer ... monoclonal antibody therapy -- which gets the cancer ... type of antigen . Disclaimer: ... cA2 monoclonal antibody (for treatment of Crohn disease ) ...

Autoimmune disorders

... or Turner's syndrome . It's more common in girls than in boys. siplizumab (previously MEDI-507) Investigational humanized anti -T cell monoclonal antibody with potential applications for treating transplant rejection , graft -versus- host disease , and autoimmune disorders such as ...

Clinical Trials

... tested the ability of the antibody to be used in combination with the p urine analogs pentostatin, fludarabine, and cladribine, and rituximab, a monoclonal antibody specific for the CD20 antigen , ... Pravachol is the most studied statin ( cholesterol -lowering drug ) in clinical trials . It is ...

Colorectal Cancer

... cancer claiming more victims. Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme research paper ... A monoclonal antibody used in the treatment of colorectal cancer that has spread. It is also being studied in the treatment of other types of cancer . It ...

Gastric cancer

... gastric cancer . In one study, gastric cancer developed in about 3% of the infected patients and none of the uninfected patients. pemtumomab A monoclonal antibody -based therapy in phase III trials (SMART) for the treatment of ovarian cancer and in phase II trials for the treatment of gastric ...

Hyperplasia

... carcinoma ; endometrial cyst ; endometrial hyperplasia ; ... [194] Pathologists can distinguish a polyclonal B- cell hyperplasia from a monoclonal B- cell lymphoma ; both are almost always associated with EBV. When a lymph node responds, it undergoes a hyperplasia with an increase in ...

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Monoclonal in Biological News

Lombardi research: Monoclonal antibodies primed to become potent immune weapons against cancer

... Washington, DC - New research suggests that monoclonal antibody therapy of cancer can be improved to be ... recognized expert in development and use of monoclonal antibodies. "Treatment modifications might be ... on reviewing the last eight years of research on monoclonal antibody treatment, suggests that a new era in ...

Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses

... (CDC) have reported the identification of human monoclonal antibodies (mAb) that neutralize an unprecedented ... methods. "There are clear settings where human monoclonal antibodies can be used strategically for both the ... mice that were exposed to H5N1 virus. "Our human monoclonal antibody protected mice from the lethal H5N1 ...

Scientists identify human monoclonal antibodies effective against bird, seasonal flu viruses

... (CDC) have reported the identification of human monoclonal antibodies (mAb) that neutralize an unprecedented ... methods. "There are clear settings where human monoclonal antibodies can be used strategically for both the ... mice that were exposed to H5N1 virus. "Our human monoclonal antibody protected mice from the lethal H5N1 ...

UC San Diego and Genentech scientists develop potentially disruptive antibody sequencing technology

... have developed a new, quicker way to sequence monoclonal antibodies a process that is many times faster ... titled, "Automated de novo protein sequencing of monoclonal antibodies." In it, the authors propose a new ... routinely used in the initial characterization of monoclonal antibodies, but subsequent mutations and other ...

Is hybridoma production about to take a quantum leap forward?

... have started to evaluate the use of fully human monoclonal antibodies as a complementary or primary ... benefits, the efficient production of human monoclonal antibodies is a high priority. But any attempt to ... human tissues. The capacity to humanize monoclonal antibodies in 1988 through hybridoma cell ...

First human gets new antibody aimed at hepatitis C virus

... of a Phase 1 clinical trial, testing the safety and activity of a human monoclonal antibody they developed that can neutralize the Hepatitis C virus (HCV). ... be neutralized and rendered unable to infect the new liver. Then, because monoclonal antibodies are highly specific and typically have little or no ...

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Monoclonal in Biological Technology

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

... growth and recurrence." OMP-21M18 is a monoclonal antibody that blocks DLL4 signaling to reduce ... "OMP-21M18 is the first of several promising monoclonal antibodies in development at OncoMed. We have ... About OMP-21M18 OMP-21M18 is a monoclonal antibody optimized to block a key signaling ...

Micromet Closes $80.5 Million Public Offering of Common Stock

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet Receives European Orphan Drug Designation for Treatment of Acute Lymphoblastic Leukemia with BiTE Antibody Blinatumomab

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet Announces Pricing of Public Offering of Common Stock

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet Announces Public Offering of Common Stock

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet, Inc. to Host Conference Call and Webcast to Report Second Quarter 2009 Financial Results on August 6, 2009

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

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Monoclonal in Biological Products

HIV-1 p24 ELISA Kit, Alliance (480 Tests) from PerkinElmer

Description:... which are coated with a highly specific mouse monoclonal antibody to HIV-1 p24. The immobilized monoclonal antibody captures both free HIV-1 p24 and that ... require disruption and are added directly to the monoclonal antibody-coated microplate wells. The captured ...
Company:PerkinElmer

Mouse Anti-ROCK-1 (cleaved) Monoclonal Antibody, Unconjugated from BioVision

Description:... ROCK-1 (cleaved) monoclonal Ab 100 ug purified mouse monoclonal antibody. Clone# 12M03. Reacts with human. Tested in Western blot ....
Company:BioVision

LEUCOPERM Suspension fixation and permeabilization solution from GeneTex

Description:... medium and fluorochrome labelled antibodies. Flow cytometric analysis with monoclonal antibodies have been restricted primarily to cell surface molecules. ... availability of suitable antibody conjugates. Most commercially available monoclonal antibody conjugates can be used with LEUCOPERMTM reagents. Some ...
Company:GeneTex

Mouse Anti-GST Tag Monoclonal Antibody, Unconjugated from Novagen

Description:... The GSTTag monoclonal Antibody is a mouse monoclonal antibody (IgG1) with high affinity to the 26 kDa glutathione-S-transferase ...
Company:Novagen

Rat Anti-Mouse IgM Heavy Chain Monoclonal Antibody, Unconjugated, Clone LO-MM-3 from Cell Sciences

Description:... Anti-Mouse IgM Heavy Chain, Clone LO-MM-3, monoclonal ...
Company:Cell Sciences

Mouse Anti-SIT Monoclonal Antibody, Unconjugated, Clone SIT-01 from Abcam

Description:... Mouse monoclonal [SIT-01] to SIT ( Abpromise for all tested applications). entrezGeneID: 27240 SwissProtID: ...
Company:Abcam

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Monoclonal in Biological Definition

Antibody

... one particular immunoglobulin will show up as a monoclonal band. Isotypes According to differences ... be detected through blood tests . "Designed" monoclonal antibody therapy is already being employed in a ... can be isolated and immortalized, then a monoclonal antibody can be obtained. ...

Monoclonal antibody

... monoclonal antibodies ( mAb ) are antibodies that are ... Given any substance, it is possible to create monoclonal antibodies that specifically bind to that ... 1 Production 2 Applications 2.1 monoclonal antibodies for cancer treatment 2.2 Chimeric ...

Biotechnology

... discovered the laws of inheritance 1919 Karl Ereky , a Hungarian engineer, first used the word biotechnology 1975 Method for producing monoclonal antibody developed by Kohler and Milstein 1980 Modern biotech is characterized by recombinant DNA technology . The prokaryote model, E. ...

Immune system

... drug immunotherapy lymphatic system / lymphocyte macrophage major histocompatibility complex / class I MHC /class II MHC monoclonal antibody / polyclonal antibody ...
Monoclonal in Biological Dictionary

Polyclonal Antibody

... production can be performed ... ... contract monoclonal and polyclonal Ab producers, an antibody ... much more. ... catalog antibodies and custom monoclonal and polyclonal antibodies . ... Companies that offer custom monoclonal and polyclonal antibody services ... Advy ...

Polyclonal antibodies

... QED Bioscience is a leading manufacturer of monoclonal and polyclonal antibodies and provides a ... for excellence in providing top quality monoclonal and polyclonal antibodies , antigens, enzymes, kinases and purified proteins ... Quality monoclonal and polyclonal antibody products, Elisa kits, ...

Monoclonal Antibody

... monoclonal antibodies (mAb or moAb) are monospecific ... Given almost any substance, it is ... monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically target ....

Monoclonal

... monoclonal antibodies (mAb or moAb) are monospecific ... Given almost any substance, it is ... monoclonal cells are defined as a group of cells produced ... that there is some method to ... monoclonal Antibody Production. A Report of the. Committee ...

Monoclonal antibodies

... monoclonal antibodies (mAb or moAb) are monospecific ... Given almost any substance, it is ... monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically target ...

Antibody

... may persist for months ... Specialize in monoclonal and polyclonal antibody development and ... because there are two ... (Redirected from monoclonal antibody ) Jump to: navigation, search ... Main article: monoclonal antibody therapy ... fact, every intact ...

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