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Metastatic in Medical News

Bionovo Presents Positive Results from Phase 1B Trial of Bezielle for Metastatic Breast Cancer

... therapy. A total of twenty-seven women with metastatic breast cancer were enrolled to the Phase 1B ... clinical activity among a cohort of patients with metastatic breast cancer who had been heavily pretreated ... of women who have been heavily pretreated for metastatic breast cancer," said Dr. Mary Tagliaferri, ...

AstraZeneca Submits New Drug Applications for ZACTIMA(TM) in Second-Line Advanced Non-Small Cell Lung Cancer

... alone in patients with locally advanced or metastatic NSCLC, treated with one prior anti-cancer ... alone in patients with locally advanced or metastatic NSCLC, treated with one prior anti-cancer ... erlotinib in patients with locally advanced or metastatic NSCLC after failure of at least one prior ...

Chicago team uses artificial intelligence to diagnose metastatic cancer

... of the lymph nodes revealed that 20 of them had metastatic cancer and 30 of them had cancer that remained ... computer would have accurately identified the 20 metastatic cases based on analyzing the ultrasound images of ... the program's potential for diagnosing metastatic disease. "We discovered that a computer ...

Delcath Systems Provides Update on Progress

... platform for the regional treatment of cancer metastatic to the liver, today reported on the Company's ... Additional Patients for Enrollment in Phase III metastatic Melanoma Trial Since Late April, Enrolled ... patient enrollment milestones in our Phase III metastatic Melanoma Trial. Based on recent trends, we ...

Genetic testing may be valuable in treating colorectal cancer

... For the 29,000 patients in the United States with metastatic colorectal cancer, chemotherapy with irinotecan ... for pretreatment pharmacogenetic testing for metastatic colorectal cancer, but remains to be verified by ... with irinotecan) chemotherapy regimen for metastatic colorectal cancer. The model assumed that under ...

Driven by Launch of Emerging Therapies, Overall Prostate Cancer Drug Market Will Increase by $2 Billion Through 2018

... Emerging Therapies to Treat metastatic Hormone-Refractory Prostate Cancer Will Capture ... by the launch of emerging therapies in the metastatic hormone-refractory population, most notably ... Prostate Cancer finds that therapies in the metastatic hormone-refractory population -- for which there ...

Nexavar in Combination with Chemotherapy Shown to Extend Progression-Free Survival in Patients with Advanced Breast Cancer

... randomized Phase 2 trial in advanced metastatic breast cancer met its primary endpoint of ... in patients with locally advanced or metastatic HER-2 negative breast cancer. Study findings ... patients. These patients had locally advanced or metastatic HER-2 negative breast cancer and had received no ...

US Oncology Research Network Participates in Phase III Follow-up Study to BiPar's Investigational Cancer Drug BSI-201

... Progesterone Receptor (PR), and HER2-negative metastatic breast cancer. Joyce O'Shaughnessy, ... which is a very promising new treatment for metastatic triple negative breast cancer," says Dr. ... or without BSI-201. Patients must have measurable metastatic breast cancer with zero to two prior chemotherapy ...

Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)

... gene as a predictive biomarker in patients with metastatic colorectal cancer (mCRC) treated with anti-EGFr ... to include that retrospective subset analyses of metastatic colorectal cancer trials have not shown a ... pre-treatment work-up for patients diagnosed with metastatic colorectal cancer. About Colorectal ...

Rare Cells Linked to Pediatric Cancers

... children with localized cancer, 22 children with metastatic cancer and 20 healthy children. Circulating ... in strikingly higher amounts in patients with metastatic disease," Francoise Farace, director of the ... Research. The finding that children with metastatic cancer had much higher levels of these cells than ...

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Metastatic in Medical Technology

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

... treatment of patients with KRAS wild-type metastatic colorectal cancer (mCRC). "We believe ... document an important advance for patients with metastatic colorectal cancer," said Roger M. Perlmutter, ... agent for the treatment of EGFR-expressing, metastatic colorectal carcinoma is based on progression-free ...

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

... long-term survival rates in patients with metastatic melanoma whose disease had been minimized by ... Anti-Tumor Vaccines in Patients with metastatic Melanoma," was published in the June 2009 issue ... for melanoma patients with recurrent or distant metastatic disease at the time of diagnosis because there ...

UPDATE: US Oncology Research Network Participates in Phase III Follow-up Study to BiPar's Investigational Cancer Drug BSI-201

... Progesterone Receptor (PR), and HER2-negative metastatic breast cancer. Joyce O'Shaughnessy, ... which is a very promising new treatment for metastatic triple negative breast cancer," says Dr. ... include adults with histologically documented metastatic breast cancer with measurable disease that is ...

CuraGen Announces Expansion of CR011-vcMMAE Phase II Trial in Advanced Breast Cancer

... treatment of melanoma and for the treatment of metastatic breast cancer, and in a Phase I trial to evaluate ... in therapy, the median survival of patients with metastatic breast cancer is 2 to 3 years, while patients ... approaches for patients with locally advanced and metastatic breast cancer who have failed other therapies. ...

Investigational Cancer Drug BSI-201 Showed Clinical Benefit in 62% of Patients with Triple-Negative Metastatic Breast Cancer and Significantly Prolonged Survival

... carboplatin (GC) chemotherapy, in patients with metastatic triple-negative breast cancer (TNBC). BSI-201 is ... damage. In this study, 116 women with metastatic TNBC, defined as tumors lacking expression of ... expect to begin a Phase 3 trial with BSI-201 in metastatic TNBC this summer. About ASCO ASCO ...

CuraGen Updates CR011-vcMMAE Data at ASCO

... median number of prior chemotherapy regimens for metastatic disease was 4 (range 2-11). Triple negative ... expand the activity of CR011 into patients with metastatic breast cancer and open this area up as an ... in addition to the opportunity in patients with metastatic melanoma," commented Dr. Timothy Shannon, ...

Neurobiological Technologies' Partner, Celtic Pharma, Announces Results of XERECEPT(R) Phase 3 Clinical Program

... XERECEPT(R) in Patients with Primary and metastatic Brain Tumors Administration of XERECEPT(R) ... cerebral edema associated with both primary and metastatic brain tumors. The Company also announced the ... use over the longer-term and the impact seen in metastatic patients, a large group with limited treatment ...

Keryx Biopharmaceuticals Announces Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... + Placebo in Patients with 2nd or 3rd Line metastatic Colon Cancer NEW YORK, June 1 ... alone in patients with second- or third-line metastatic colon cancer," was presented yesterday in a ... the United States, patients with 2nd or 3rd line metastatic colon cancer were randomized to receive ...

Encouraging First Data on New Targeted Treatment for Patients With Melanoma - the Deadliest Form of Skin Cancer

... to the liver, lung and bone[i]. Historically, metastatic melanoma patients live less than two months ... if caught early but patients who develop metastatic disease are rarely cured with available ... been observed - Regression of metastatic lesions in every site to which melanoma ...

Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients

... locally advanced (Stage IIIA or Stage IIIB) or metastatic (Stage IV or cancer that has spread) non-small ... II or Stage III when surgery is not an option) or metastatic (Stage IV) adenocarcinoma of the pancreas. GEMZAR ... FDA for the first-line treatment of patients with metastatic breast cancer after they have received another ...

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Metastatic in Medical Products

Feridex I.V.®

Description:... which is a common cancer in the United States. The ability to identify metastatic tumors in the liver has a significant impact on physicians' treatment plans for cancer. Because treatment plans can vary widely based on the level of metastatic disease, proper staging is a critical component of patient management. ...
Company:Advanced Magnetics, Inc.

KRONUS OptiQuant™ Thyroglobulin (OQTg) Kit

Description:... Thyroglobulin (OQTg) Kit is intended for the quantitative determination of thyroglobulin (Tg) in human serum as an aid in the detection of local and metastatic thyroid tissue in patients who have had thyroid gland ablation (using thyroid surgery with or without radioiodine) and who lack serum thyroglobulin ...
Company:KRONUS

Biomet Low Profile Tibial Nail

Description:... of difficult tibial fractures. The Biomet Low Profile Tibial Nail is primarily indicated in the treatment of unstable fractures, tibial nonunion, and metastatic disease with pathologic or impending fractures but particularly useful in the treatment of very distal tibial ....
Company:Biomet Orthopedics, Inc

TPS-C

Features:... Plate Spacer (TPS) Spinal System implants are intended to replace vertebral body structures following a vertebrectomy/corpectomy of the spine for metastatic spine disease in the cervical and /or Cervico- thoracis spine (C3 T2). The TPS Spinal System implants are intended to correct spinal alignment and ...
Company:Interpore Cross International, Inc.
Metastatic in Medical Definition

Ocular oncology

... 4.1 Specific types Eye cancer Origin and location Eye cancers can be primary (starts within the eye) and metastatic cancer (spread to the eye from another organ). The two most common cancers that spread to the eye from another organ are breast cancer and lung ...
Metastatic in Medical Dictionary

Brain surgery

... s) ... Brain Surgery Brain Tumor - metastatic ( metastatic Brain Tumor ) Brain Tumor - Primary ( Primary Brain Tumor ) Brain Tumor - Secondary ( metastatic Brain Tumor ) Brain Wave Test ( EEG ) ... As ...

Metastatic brain tumor

... metastatic brain tumor Definition: A metastatic brain tumor is a mass of cancer ous cells in ... have spread from another part of the body. metastatic brain tumor Powered by: This information is ...

Bone scan

... administered by injection , for pain relief in patients suffering from metastatic carcinoma to the bone as demonstrated by enhancement on bone scan s. In some cases a bone scan is also performed to rule out metastatic disease . Im aging procedures that assist in identifying the pain ...

Carcinoid tumor

... in growth, and asymptomatic , not all patients require treatment of metastatic disease at diagnosis . Carcinoid tumor s have been called " cancer ... control of chemotherapy -induced diarrhea and flushing in patients with metastatic carcinoid tumor s and vasoactive intestinal peptide-secreting tumor s ( ...

Colon Cancer

... options with your healthcare professional. Targeting Liver Extends metastatic Colon Cancer Survival THURSDAY, March 2 (HealthDay News) -- Delivering ... s tremendous blood and lymph atic supply it is a frequent site for metastatic cancer . Cancer s which commonly metastasize to the liver include ...

Melanoma

... to interleukin-2 (IL-2) for the treatment of patients with advanced metastatic melanoma with liver metastases deemed "unapprovable" by the FDA. ... confirm if cells have turned malignant. Living more than 5 years with metastatic cancer to the lungs is uncommon. Rarely, patients with certain types ...

Primary brain tumor

... Oligodendroglioma Pictures & Images ... Primary brain tumor s metastatic brain tumor s Structural abnormality of the brain, ventricle s, ... metastasizes outside the central nervous system , usually to bone. metastatic brain tumor s occur in about one-fourth of all cancer s that metastasize ...

Renal cell carcinoma

... ); and serious kidney infection s. Living more than 5 years with metastatic cancer to the lungs is uncommon. Rarely, patients with certain types ... and a rare type of stomach cancer , increased survival for people with metastatic renal cell carcinoma , the most common type of kidney cancer . Renal ...

Bacterial Infections

... by severe bacterial infections ( sepsis ), extensive burns , trauma , retained dead fetus , heat stroke , mismatched blood transfusion , metastatic cancer , and some forms of leukemia . include chronic dermatitis , seborrhea or eczema , and allergies , particularly to soaps, colored ...

Bladder

... the GALL BLADDER . Digestive System Abnormalities - Congenital structural abnormalities of the DIGESTIVE SYSTEM. Living more than 5 years with metastatic cancer to the lungs is uncommon. Rarely, patients with certain types of cancer ( sarcoma , renal cell carcinoma , bladder cancer , colon ...

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Metastatic in Biological News

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

... long-term survival rates in patients with metastatic melanoma whose disease had been minimized by ... Anti-Tumor Vaccines in Patients with metastatic Melanoma," was published in the June 2009 issue ... for melanoma patients with recurrent or distant metastatic disease at the time of diagnosis because there ...

Colorectal cancer

... genetic signature which distinguishes tumors with metastatic potential from those that do not metastasize. ... They discovered that this gene is more active in metastatic tumors and metastases than in non-metastatic ... will help determine early on whether a tumor has metastatic potential. The doctors could then adapt the ...

LSUHSC research describes function of key protein in cancer spread

... During the transition from a localized tumor to metastatic disease, cancer cells acquire the ability to ... According to the American Cancer Society, metastatic cancer is a cancer that has spread from its ... have metastases at the time of their death, and metastatic disease is directly responsible for the majority ...

Microparticle immune response modifier shows broad effects against recurrent or metastatic cancer

... to significantly reduce the number and size of metastatic tumors in preclinical mouse models of lung and ... towards limiting tumor reoccurrence or metastatic disease." Immune response modifiers (IMRs) ... including progressive multiple sclerosis and metastatic disease," said Simon Wilkinson, Innate ...

New drug shows promise in treating drug-resistant prostate cancer

... A new therapy for metastatic prostate cancer has shown considerable promise in ... on survival in a large group of patients with metastatic prostate cancer. MDV3100 and RD162 are ... common treatment for the disease in its advanced, metastatic stage. Anti-androgen drugs, such as bicalutamide ...

New medications show promise in treating drug-resistant prostate cancer

... A new therapy for metastatic prostate cancer has shown considerable promise in ... on survival in a large group of patients with metastatic prostate cancer. The drugs are ... common treatment for the disease in its advanced, metastatic stage. Antiandrogen drugs, such as bicalutamide, ...

Metastatic bone disease patients can walk in Lazarus' footsteps

... procedure to treat the painful effects of metastatic bone disease by injecting bone cement to support ... of life can be severely affected when they have metastatic bone disease. Normal daily activities can become ... of their primary cancers," added Anselmetti. metastatic bone disease is a painful condition that can ...

NYU Langone Medical Center researchers find micro RNA plays a key role in melanoma metastasis

... called microRNA (miRNA) that is over-expressed in metastatic melanoma cell lines and tissues. ... may be an effective therapeutic strategy for metastatic melanoma, according to Eva Hernando, Ph.D., ... the first study to examine the role of miRNA in metastatic melanoma. "Melanoma becomes ...

Team finds breast cancer gene linked to disease spread

... and, at the same, time decrease the risk of metastatic dissemination," said Yibin Kang, an assistant ... illustrate the difference between localized and metastatic cancer: 98.1 percent of patients with localized ... by one, in breast tumor cells and tested their metastatic behavior in laboratory mice. The scientists ...

Expanding cell girth indicates seriousness of breast cancer

... and found cells that expanded the most were metastatic cancer, the term used when the disease has spread ... the cell's structure, or cytoskeleton. A metastatic cancer cell cytoskeleton is more prone to ... size, with the biggest deformity appearing in the metastatic cells. "Our approach - microfluidic ...

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Metastatic in Biological Technology

Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update

... of picoplatin for the first-line treatment of metastatic CRC at the 2009 American Society of Clinical ... for the first-line treatment of patients with metastatic CRPC at the 2009 ASCO Annual Meeting. The updated ... prednisone is active as first-line therapy for metastatic CRPC as demonstrated by several endpoints, ...

Sanofi-aventis Announces Second Quarter 2009 Results

... as a first line treatment for women with metastatic breast cancer, based on the results of the AVADO ... an adjuvant and as a first-line treatment in the metastatic phase, achieved second-quarter growth of 10.0% in ... in association with chemotherapy in women with metastatic triple negative breast cancer (mTNBC), i.e. with ...

Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer

... the prognosis and survival in patients with metastatic breast cancer (MBC), according to a newly ... the patient's blood. "Measuring CTCs in metastatic breast cancer patients provides oncologists with ... test in therapeutic monitoring of patients with metastatic disease." Study Design A retrospective ...

New Report Just Published: World Prostate Cancer Therapeutics Market Report

... Unveils Results of PCK3145 in Patients with metastatic Prostate Cancer II-54 Peregrine ... Unveils New Therapeutic Cancer Vaccine For metastatic Prostate Cancer II-64 PNNL and IsoRay ... Unveils Results of PCK3145 in Patients with metastatic Prostate Cancer III-69 Ambrilia Reveals ...

OncoGenex Pharmaceuticals Completes Amendment to Phase 3 Special Protocol Assessment for Confirming Survival Benefit in Patients Receiving OGX-011 with First-Line Docetaxel for Metastatic Prostate Cancer

... controlled, international study in 800 men with metastatic CRPC who are in need of first-line chemotherapy. ... median overall survival in patients with advanced metastatic prostate cancer who were treated with OGX-011 ... two Phase 3 registration trials with OGX-011 in metastatic castrate resistant prostate cancer, subject to ...

Oncothyreon announces initiation of Phase 3 trial of Stimuvax in breast cancer

... receptor-positive, locally advanced, recurrent or metastatic breast cancer. Stimuvax is an investigational ... non-resectable locally advanced, recurrent or metastatic breast cancer receiving hormonal therapy will be ... for patients with hormone receptor positive metastatic breast cancer." "The initiation of the STRIDE ...

AEterna Zentaris Discloses Preliminary Phase 2 Trial Results for Perifosine in Combination with Radiotherapy for Non-Small Cell Lung Cancer

... the disease targets of both multiple myeloma and metastatic colon cancer where, unlike the non-small cell ... positive Phase 2 data for multiple myeloma and metastatic colon cancer were presented at ASH and ASCO ... agent use of perifosine in patients with advanced metastatic renal cancer and in combination with capecitabine ...

Delcath Systems Granted Third Orphan Drug Designation

... its proprietary treatment method for primary and metastatic cancers to the liver, announced today that the ... for the treatment of neuroendocrine tumors metastatic to the liver. The trial is treating patients ... drug melphalan for the treatment of patients with metastatic cutaneous melanoma ...

Micromet Presents Update at ASCO 2009 on a Phase 1b Combination Study of Adecatumumab and Docetaxel

... the chemotherapeutic docetaxel in patients with metastatic breast cancer (MBC) at the annual meeting of the ... in combination with docetaxel for patients with metastatic breast cancer: Results of a multicenter phase Ib ... antibody, as monotherapy in patients with metastatic breast cancer. Annals of Oncology, in press. ...

OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer

... in combination with second-line treatment of metastatic castrate resistant prostate cancer showing better ... Phase 3 registration trials with OGX-011 in metastatic castrate resistant prostate cancer, subject to ... from the FDA for the treatment of progressive metastatic prostate cancer in combination with docetaxel. ...

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Metastatic in Biological Products

Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex

Description:... epithelial cells and colorectal cancers on formalin-fixed, paraffin-embedded tissue sections. Therefore clone CDX2-88 may be used in identifying metastatic colon ....
Company:BioGenex
Metastatic in Biological Definition

Cancer

... in situ refers to an uncontrolled growth of cells that remains in the original location. However, carcinoma in situ may develop into an invasive, metastatic malignancy and, therefore, is usually removed surgically, if possible. Heredity Most forms of cancer are "sporadic", and have no basis in ...

Liver

... of iron in the body, eventually leading to liver damage Cancer of the liver (primary hepatocellular carcinoma or cholangiocarcinoma and metastatic cancers, usually from other parts of the gastrointestinal tract ) Wilson's disease , a hereditary disease which causes the body to retain ...
Metastatic in Biological Dictionary

Wildtype

... differing from the wildtype . ... Findings from three studies demonstrate the increased efficacy of Erbitux® (cetuximab) in patients with metastatic colorectal cancer (mCRC) who have a wild-type ... Britannica online encyclopedia article on wild type (genetics), ... ... Aspects of ...

Proteolysis

... 2009, from www.yourdictionary.com/ proteol ysis . Comments: ... Background—The process of proteolysis is important at several stages of the metastatic cascade. ... This is indicative of proteolysis occurring in vivo and has ... By performing concentration-dependent proteolysis , HDAC1 double ...
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(Date:7/10/2014)... The Capital Institute for Neurosciences at Capital Health ... a clinical trial that delivers chemotherapy to brain tumors ... the procedure, done at Capital Health Medical Center – ... tiny catheter through the patient’s femoral artery in the ... the brain. Once the catheter reached the brain, chemotherapy ...
(Date:7/10/2014)... Colorado (PRWEB) July 10, 2014 ... will gather in Copenhagen this July 13-17 to ... bringing the world closer to breakthroughs in dementia ... the world’s largest conference of its kind. , ... AAIC serves as a catalyst for generating new ...
(Date:7/10/2014)... 10, 2014 In his latest blog ... drug treatment facility CEO Per Wickstrom has listed 5 ... trying to confirm an appointment, get information or sometimes ... following-up without being annoying is a skill that most ... a way to keep the dialogue moving without coming ...
(Date:7/10/2014)... (July 8, 2014) A new study from Colorado ... improvements, poor oral health remains a major problem in ... "The oral health among Native Americans is abysmal with ... of the country," said Terrence Batliner, DDS, MBA, associate ... at the School of Public Health. "The number one ...
(Date:7/10/2014)... THURSDAY, July 10, 2014 (HealthDay News) -- Teens who ... are more likely to develop emotional symptoms such as ... factors such as these that may exacerbate issues teens ... appropriate treatment and in making decisions about when to ... school for these athletes," study authors Lisa Koehl and ...
Breaking Medicine News(10 mins):Health News:New Trial Delivers Chemotherapy to Brain Tumor Through Artery in Leg 2Health News:New Trial Delivers Chemotherapy to Brain Tumor Through Artery in Leg 3Health News:Per Wickstrom’s Latest Blog Post Lists 5 Ways to Follow-up Without Being Annoying 2Health News:Study finds widespread oral health problems among Navajo 2Health News:Some Teens May Face Emotional Problems After Concussion 2
(Date:7/10/2014)... found in your popcorn or soap might not be ape ... according to an analysis in the Cell Press journal ... for vegetable oil has already led to the conversion of ... orangutans in particular. If guidelines are not put in place ... plantations from Asia into Africa will be bad news for ...
(Date:7/10/2014)... English Channel has resulted in the removal of many ... the barrel, for increasing amounts of shellfish to make ... other species at the head of the food chain ... area completely., These are some of the findings of ... in association with international non-profit research organization WorldFish. They ...
(Date:7/10/2014)... Israel Ben-Gurion University of the Negev scientists have ... where they warm up before the evening hunt. ... the environment to regulate,their internal temperature. The researchers believe ... the scorpions to increase their body temperature before they ... , After trapping the wild large-clawed scorpions ( Scorpio ...
Breaking Biology News(10 mins):Hunger for vegetable oil means trouble for Africa's great apes 2Overfishing in the English Channel leaves fisherman scraping the bottom of the barrel 2Overfishing in the English Channel leaves fisherman scraping the bottom of the barrel 3Scorpions are master architects, according to new research from Ben-Gurion University 2
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