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Metabolize in Medical News

FDA Warns of Codeine Risk for Some Nursing Mothers

... Some women metabolize the drug quickly, raising chance of morphine ... mothers who use medicines containing codeine and metabolize the drug quickly may be putting their baby at ... These women are genetically predisposed to metabolize codeine more rapidly and completely than other ...

Gene Mutation Increases Drug Toxicity, Rejection Risk in Pediatric Kidney Transplants

... -- Screening for mutations in a gene that helps the body metabolize a kidney transplant anti-rejection drug may predict which children are at ... specific point mutation in the gene that helps break down the drug, UGT, metabolize the drug slower. This point mutation, called UGT1A9-331, causes ...

Story ideas for health reporters covering the summer Olympic Games

... exercise causes lactic acid levels to build up faster than the body can metabolize it. For athletes, this can be good because in the process of generating ... Running Economy How well your muscles use oxygen and how well they can metabolize glucose without producing a lot of lactic acid in the skeletal muscle ...

A Sweet Way to Shield Baby's Teeth

... he added. A diet high in sugar promotes the bacteria that take in sugars, metabolize them, and produce the lactic acid that creates tooth decay, the researcher ... he added. The bacteria, which are the "bad actors" here, can't metabolize sugars from xylitol, and so they die off, Milgrom explained. Only the ...

Research findings may lead to new ways to study and fight diabetes

... Normally, a hormone called insulin signals a persons cells to take in and metabolize glucose. In diabetics, however, either not enough insulin is being ... and fatty acids in a very precise balance to regulate their metabolism. To metabolize fatty acids, PPAR-alpha breaks them up into small pieces and can then ...

Anti-smoking strategy targets fourth-graders, parents in rural and urban Georgia

... are huffing and puffing on or that you are exposed to. Whites tend to metabolize and excrete nicotine more quickly than blacks, resulting in more adverse ... in blacks, according to her previous studies looking at four genes that metabolize nicotine. Smoking rates among all Georgia students have increased since ...

Patents Issued Covering Stable Tablet Formulation and Once Daily Dosing Regimen for Kuvan

... form of 6R-BH4 (tetrahydrobiopterin), a naturally occurring enzyme cofactor that works in conjunction with phenylalanine hydroxylase (PAH) to metabolize Phe. Kuvan has received orphan drug designation from both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency ...

European Medicines Agency (EMEA) Approves Cell Therapeutics, Inc.'s September Meeting Request to Discuss OPAXIO(TM) Marketing Authorization Application

... allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy. Preclinical and clinical studies support that OPAXIO metabolism by lung cancer cells may ...

The microbial hydrocarbon diet

... the hydrocarbon n-hexadecane. The bacterium was initially isolated from the Daqing oil field in North East China where it had evolved the ability to metabolize this chemical. Bioremediation of hydrocarbons usually involves the application of a cultured bacterium that has been optimized to feed on the ...

Some Antidepressants May Thwart Tamoxifen's Effect on Breast Cancer

... (Femara) and exemestane (Aromasin), "are one possible alternative to tamoxifen. There are also genotyping issues -- how different individuals metabolize the various drugs. This is not standard of care but it can be checked." More information There's more on tamoxifen at the U.S. National ...

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Metabolize in Medical Technology

OPAXIO(TM) Combined with Alimta(R) Well Tolerated in Dose-Ranging Study of Patients with Advanced Non-Small Cell Lung Cancer

... allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy. Preclinical and clinical studies support that OPAXIO metabolism by lung cancer cells may ...

Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer

... allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy. Preclinical and clinical studies support that OPAXIO metabolism by lung cancer cells may ...

ELAD(R) Liver Support System Study Initiated at Multiple U.S. Centers

... hollow fibers. The patient's plasma flows inside of the hollow fibers to allow two-way transfer of metabolites. During ELAD therapy the cells metabolize toxins and synthesize proteins and other liver specific products essential for life. The ELAD cell cartridges are produced at VTI's GMP-compliant ...

Mission Pharmacal Launches CitraNatal(R) Assure Prescription Prenatal Vitamin

... nervous system(5) and may help some women reduce severe nausea or vomiting during pregnancy(6). It also helps the body maintain blood glucose levels, metabolize proteins, formulate neurotransmitters for normal nerve cell communication and makes hemoglobin to carry oxygen to tissues(7). Pregnant women ...

Complete Study Results Comparing CTI's OPAXIO(TM) With Gemcitabine or Vinorelbine in Performance Status (PS 2) NSCLC Patients Published in Journal of Thoracic Oncology

... allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside the tumor cell, enzymes metabolize the protein polymer, releasing the paclitaxel chemotherapy. Preclinical and clinical studies support that OPAXIO metabolism by lung cancer cells may ...

BioMarin Announces FDA Approval for Kuvan

... form of 6R-BH4 (tetrahydrobiopterin), a naturally occurring enzyme cofactor that works in conjunction with phenylalanine hydroxylase (PAH) to metabolize Phe. BioMarin and Merck Serono estimate that Kuvan could be a potential treatment option for approximately 30 percent to 50 percent of the estimated ...

Synvista Therapeutics Announces Initiation of Phase 2 Study With Alagebrium for Chronic Heart Failure

... pharmaceutical markets. The Company's portfolio includes orally bioavailable, organoselenium mimics of glutathione peroxidase. These compounds metabolize lipid peroxides and have the potential to limit myocardial damage subsequent to a myocardial infarction. The Company is developing a clinical ...

Vital Therapies Announces Presentation of ELAD(R) 'Artificial Liver' Data at American Association for the Study of Liver Diseases 2007 Annual Meeting

... and severity of liver disease. The system consists of four cartridges containing cells that function like normal human liver hepatocytes. The cells metabolize toxins and remove waste products while delivering essential proteins into the plasma. These cartridges are incorporated into a blood pumping system ...

Synvista Announces New Data Showing Haptoglobin Type Predicts Effectiveness of Tight Glycemic Control on Cardiovascular Outcomes in Patients with Diabetes

... pharmaceutical markets. The Company's portfolio includes orally bioavailable, organoselenium mimics of glutathione peroxidase. These compounds metabolize lipid peroxides and have the potential to limit myocardial damage subsequent to a myocardial infarction. The Company is developing a clinical ...

Synvista Collaboration Demonstrates in Preclinical Studies the Mechanism for Defective Cholesterol Transport in Patients with Diabetes

... pharmaceutical markets. The Company's portfolio includes orally bioavailable, organoselenium mimics of glutathione peroxidase. These compounds metabolize lipid peroxides and have the potential to limit myocardial damage subsequent to a myocardial infarction. The Company is developing a clinical ...

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Metabolize in Medical Dictionary

Galactosemia

... is the inability of the body to use ( metabolize ) the simple sugar galactose (causing the ... disorder in which the baby is unable to metabolize galactose , a milk sugar . It occurs in ... by a genetic lack of an enzyme needed to metabolize galactose into glucose . May result in ...

Metabolize

... metabolize Definition: Metabolism is the process of ... into energy. For example, food protein s are metabolize d into energy or heat to be used or absorbed by the body. metabolize and store carbohydrates , which are used as the ...

Phenylketonuria

... an inherited disease in which the body cannot metabolize a protein c alled phenylalanine . It is ... rare inherited disorder. Causes an inability to metabolize phenylalanine , an amino acid that's a common ... phenylketonuria ( PKU ). These people cannot metabolize foods that contain large amounts of ...

Pku

... an inherited disease in which the body cannot metabolize a protein c alled phenylalanine . It is ... the amino acid phenylalanine is not properly metabolize d. PKU can cause severe mental retardation if ... rare inherited disorder. Causes an inability to metabolize phenylalanine , an amino acid that's a common ...

Bilirubin

... it into the digestive tract. Bilirubin . Normally your liver metabolize s this residue of worn-out red blood cells, and you excrete it in your urine . But hepatitis interferes with your liver 's ability to metabolize bilirubin , leading to higher levels in your blood . Enzyme levels. ...

Galactose

... mia - This is an inherited disorder in which the baby is unable to metabolize galactose , a milk sugar . It occurs in about one baby in every ... present at birth caused by a genetic lack of an enzyme needed to metabolize galactose into glucose . May result in mental retardation , ...

Glucose

... blood . The glucose tolerance test measures the body's ability to metabolize glucose . Pictures & Images Urine Sample ... 3-Hour Glucose ... glucose levels. The lack of insulin results in an inability to metabolize glucose , and the capacity to store glycogen (a form of glucose ) in ...

Phenylalanine

... ( PKU ) - PKU is an inherited disease in which the body cannot metabolize a protein c alled phenylalanine . It is estimated that one baby in ... type 1 (HT-1). Mfg: Orphan Pharmaceuticals USA. These people cannot metabolize foods that contain large amounts of phenylalanine , one of the ...

Albumin

... (synthesize) protein s, including albumin (to help maintain the volume of blood ) and blood clotting factors Synthesize, store, and process ( metabolize ) fats, including fatty acids (used for energy) and cholesterol ... It produces important protein s for the blood , notably albumin (which ...

Aspartic acid

... that our bodies produce it even if we don't get this amino acid from the food we eat. - Amino Acids - Aspartic Acid - Carbohydrates - metabolize Review Date : 10/17/2003 Reviewed By : David Webner, M.D., Sports Medicine Fellow, Crozer-Keystone Family Practice Program, Springfield, PA. ...

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Metabolize in Biological News

Gene mutation increases drug toxicity, rejection risk in pediatric kidney transplants

... CINCINNATI Screening for mutations in a gene that helps the body metabolize a kidney transplant anti-rejection drug may predict which children are at ... a specific point mutation in the gene that helps break down the drug, UGT, metabolize the drug slower. This point mutation, called UGT1A9-331, causes ...

Syracuse University scientists discover how some bacteria may steal iron from their human hosts

... the researchers observed that Streptomyces could ingest iron-citrate, metabolize the iron, and use the citrate as a free source of energy. Other ... additional energy to ingest the iron. Once in the cell, the bacteria metabolize the iron and, as an added bonus, use the citrate as an energy source. ...

Common allergy drug reduces obesity and diabetes in mice

... contrast, type 2 diabetes is a strictly metabolic condition in which cells grow increasingly deaf to insulin signals and thus lose their ability to metabolize glucose. In both cases, glucose mounts in the blood, at times to fatal levels. But it is becoming increasingly clear that we should also think of ...

Phthalic symbol

... as the only source of carbon for the microbes. Successive divisions of microbial cells quickly leads to the evolution of a strain that can quickly metabolize the phthalate and convert it into the raw materials for microbial growth and reproduction. The researchers then tested this phthalate-digesting ...

A little java makes it easier to jive, researcher says

... common for athletes before competing to consume a variety of substances that include caffeine, motivated by "the notion that it will help you metabolize fat more readily." "That research isn't actually very compelling," Motl said. "What's going on in my mind is people are doing it for that reason, ...

Stanford scientists find new solutions for the arsenic-poisoning crisis in Asia

... Normally, bacteria use oxygen to breathe. But in an anaerobic environment, they can use other chemicals, including rust and arsenic. As the bacteria metabolize the iron and arsenic, they convert it to a form that readily dissolves in water. "As these sediments get buried very rapidly, the bacteria go ...

Fowl soil additive breaks down crude oil

... remediation exercise is complete. A more environmentally benign approach is to bioremediation, which uses natural or engineered microbes that can metabolize the organic components of crude oil. Stimulating such microbial degradation in contaminated soil often involves the use of expensive fertilizers ...

Great Lake's sinkholes host exotic ecosystems

... associated with rotting eggs. Where the sinkholes are deeper still and light fails, microorganisms use chemical means rather than photosynthesis to metabolize the sulfurous nutrients. Biddanda, Ruberg, and their team are probing the origins of ancient minerals flowing in from beneath this fresh inland ...

States expand newborn screening for life-threatening disorders

... was born in was part of a pilot program to expand newborn screening in California." 3MCC is a serious disorder that leaves newborns unable to metabolize leucine an essential amino acid found in many forms of protein. But because Giana, now age six, was diagnosed early, she was put on a special diet ...

MUHC and McGill scientists explain genetic disease first discovered in Quebec 24 years ago

... into its basic properties and how it behaves in healthy cells." The cblF idisease is a rare genetic disorder characterized by an inability to metabolize vitamin B12. Patients afflicted with this condition build up toxic levels of homocysteine and methylmalonic acid in their bodies. Vitamin B12, which ...

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Metabolize in Biological Technology

Prometheus Strengthens Intellectual Property Portfolio with Newly Issued Patents for Thiopurine Metabolite Testing

... vary due to each person's ability to process or metabolize thiopurines. Most people have no problem ... percent of patients have almost no ability to metabolize these drugs. Failure to metabolize thiopurines can result in myelosuppression ...

Center for Molecular Medicine Only Regional Provider of Test Suggested in FDA Alert on Prescribing Codeine to Nursing Mothers

... order a CYP2D6 genotyping test to determine how the patient will metabolize codeine in advance of its prescription. The FDA noted that when codeine ... available at the CMM, tell a physician how rapidly a specific patient will metabolize codeine based on a patient's genetic makeup. "The CMM was created to ...

Kuvan Receives Priority Review Status From Health Canada

... form of 6R-BH4 (tetrahydrobiopterin), a naturally occurring enzyme cofactor that works in conjunction with phenylalanine hydroxylase (PAH) to metabolize Phe. Kuvan has received orphan drug designation from both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMEA). ...

Kibow Biotech, Inc. to Present at BIO 2009 International Convention: Innovations to Heal, Fuel, and Feed the World

... (probiotics) that possess a high affinity for various nitrogenous waste products. When the kidneys are unable to filter toxins normally, the microbes metabolize the renal waste products and use them as nutrients for growth. As the microbes grow and replicate, they create colonies capable of utilizing even ...

Kibow Biotech, Inc. Launches Breakthrough Probiotic Dietary Supplement for Kidney Health in USA and Canada

... and specifically selected beneficial microbes (probiotics) that possess a high affinity for various nitrogenous waste products. The microbes metabolize the waste products and use them as nutrients for growth. As the microbes grow and replicate, they create colonies capable of utilizing even more ...

BioMarin Receives Notice of Allowance for Once Daily Dosing Patent for Kuvan

... form of 6R-BH4 (tetrahydrobiopterin), a naturally occurring enzyme cofactor that works in conjunction with phenylalanine hydroxylase (PAH) to metabolize Phe. Kuvan has received orphan drug designation from both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMEA). ...

Video: Accera Launches Axona(TM), First Medical Food Therapy to Help Manage Mild-to-Moderate Alzheimer's Disease

... Alzheimer's disease is a progressive and fatal neurological disease characterized by a substantial decrease in the brain's ability to metabolize glucose, which is the brain's primary source of energy. Known as hypometabolism, this defect may contribute to both the clinical and pathological ...

Kuvan Receives Positive Opinion From CHMP for European Approval

... form of 6R-BH4 (tetrahydrobiopterin), a naturally occurring enzyme cofactor that works in conjunction with phenylalanine hydroxylase (PAH) to metabolize Phe. BioMarin and Merck Serono estimate that Kuvan could be a potential treatment option for approximately 30 percent to 50 percent of the estimated ...

ESA Receives 2008 Frost & Sullivan North American Technology Innovation Award for Development of Integrated Metabolomics Systems

... This can be very useful in new FDA-mandated drug safety testing to evaluate active/toxic human drug metabolites. Studies have shown that drugs can metabolize differently in humans than in other animals, resulting in potentially toxic levels of drug metabolites that can't be identified by animal studies ...

New yeast trick for eating favorite food: Details in Nature paper

... the glucose network actively shuts down the galactose network by degrading messenger RNA that would otherwise go on to form the enzymes needed to metabolize galactose. "To find something new in the well-known galactose network after predicting it is extremely exciting," said Matthew Bennett, the first ...

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Metabolize in Biological Definition

Ames test

... is observed. S-9 In some Ames assays an S-9 mix is added. The S-9 mix contains liver enzymes , generally from a rat. These enzymes can metabolize the agent being tested in order to predict the mutagenic properties within a living system, specifically the source of the S-9 enzymes. ...
Metabolize in Biological Dictionary

Genomic library

... fumigatus. ... pWE15 and pLORIST2 genomic cosmid libraries of A. nidulans ... Second, we digest the genomic DNA of an organism that can metabolize lactose ... this strategy to make a library of genomic E. coli fragments in plasmids that ... ...

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(Date:7/29/2014)... July 29, 2014 The global market ... million by 2020, growing at an estimated CAGR of ... study by Grand View Research, Inc. Introduction of technological ... by the geriatric population, along with increase in demand ... major drivers of this market. In addition, presence of ...
(Date:7/29/2014)... The National Foundation for Infectious Diseases ... of A Silver Award winner for "Keeping the ... age six months and older to be vaccinated against ... power to enrich lives through its steady communications effort ... about the importance of vaccination. , “Congratulations ...
(Date:7/29/2014)... Riverdale Urgent Care is making community service ... presence at local events, partnerships and other initiatives, the ... a medical service for the Riverdale neighborhood. , ... of Riverdale RiverFest and South Riverdale Street Fair. Riverdale ... musicians and entertainers, arts and crafts, boat rides and ...
(Date:7/29/2014)... The Cottages Investment Group, LLC ... MeadowLands Memory Care, to break ground July 30, 2014. ... memory loss and forms of dementia, Wade T. Micoley, ... of Oconto Fall’s first assisted living facility with a ... Cottages Investment Group, LLC will license the facility as ...
(Date:7/29/2014)... (PRWEB) July 29, 2014 In today’s world, ... difficult to get. Snoring and sleep apnea (a medical problem ... people and their bed partners of the rest they need ... of the population snores and 20 million people in the ... have been diagnosed and treated; and of those treated, many ...
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(Date:7/28/2014)... tool that can help advance the genetic engineering ... bioenergy, has been developed by researchers with the ... (JBEI), a multi-institutional partnership led by Lawrence Berkeley ... developed an assay that enables scientists to identify ... critical components in the biosynthesis of plant cell ...
(Date:7/28/2014)... to prevent and treat HIV infection has been problematic ... molecules can arouse as they get rid of the ... Weizmann Institute and the National Institutes of Health (NIH) ... interferons around the time of infection could ... Their research appeared in Nature . , ...
(Date:7/28/2014)... at Harvard University today announced that its human ... formed private company to accelerate development of pharmaceutical, ... The announcement follows a worldwide license agreement between ... start-up Emulate Inc., relating to the use of ... "This is a big win towards achieving our ...
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