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Metabolism in Medical News

Therapy should extend beyond childhood

... during the course of the disease, the products of metabolism cause not only acute, but chronic toxic damage as ... In addition, intensive emergency treatment of the metabolism must be carried out to prevent a metabolic crisis ... during the course of the disease, the products of metabolism cause not only acute, but chronic toxic damage as ...

Brain Imaging (MRI/PET) and Measurements of Proteins in Spinal Fluid May Improve Alzheimer's Prediction and Diagnosis

... measured with MRI; relative rates of glucose metabolism in certain, prespecified brain regions measured ... on those two measurements - that is, low glucose metabolism combined with poor memory performance - were 15 ... Medicine, declines in regional cerebral glucose metabolism (rCMglc) in the brain as measured with Positron ...

Memory test and PET scans detect early signs of Alzheimer's

... scores on a memory recall test and low glucose metabolism in particular brain regions, as detected through ... found in the cerebrospinal fluid; and glucose metabolism detected in PET brain scans. A low rate of glucose metabolism in a particular brain region is considered a sign ...

Arete Therapeutics Presents Positive Clinical and Preclinical Data for AR9281

... type 2 diabetes. sEH is an enzyme involved in the metabolism of arachidonic acid, a key signaling molecule ... of concept that sEH inhibition modulates glucose metabolism or blood pressure in patients with impaired ... demonstrate that AR9281 improves glucose metabolism in rodent models of type 2 diabetes. -- "A ...

Making Obese Mice Slim, Without Diet or Exercise

... appear in two studies in the June issue of Cell metabolism . In one of the studies, researchers inserted ... use this shunt pathway to manipulate fatty acid metabolism in the liver is very exciting as a basic science ... of Medicine, New York City; June 2009, Cell metabolism ...

Key protein may explain the anti-aging and anti-cancer benefits of dietary restriction

... that plays a key role in tumor formation, oxygen metabolism and inflammation is involved in a pathway that ... pathway known to regulate cell growth and metabolism in response to nutrients and growth factors. ... HIF-1 have mainly focused on its roles in oxygen metabolism and tumor development", said Buck faculty member ...

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Metabolism in Medical Technology

ALP Life Sciences, LLC Announces Nanoveson(TM) Patent Filing and Whitepaper Availability on Proposed Therapy for Non-Alcoholic Fatty Liver Disease (NAFLD) and Comorbid Diseases

... to the life sciences industry in the area of drug metabolism testing. Research has demonstrated that ... research focused on blocking arachidonic acid metabolism along cytochrome P450, leukotriene, ... thromboxane eicosanoid pathways. Arachidonic acid metabolism is implicated in many inflammatory diseases, ...

Bionovo Reports on Metabolic Studies Related to Its Menopausal Hot Flash Drug Candidate

... and Disposition, entitled "Oxidative In Vitro metabolism of Liquiritigenin, a Bioactive Compound Isolated ... clinical testing. The paper describes in vitro metabolism of Liquiritigenin which is almost exclusively ... . "Most adverse drug reactions are linked to metabolism of the drug in the human body. Many women of ...

Embryo Viability Studies Support Utility of Novel, Metabolomic Profiling Technology

... of the same morphology. This indicates that the metabolism of the embryo -- and therefore, its reproductive ... small molecular compounds produced by cellular metabolism which, when evaluated as a whole, represent ... disease), maternal fetal medicine, pulmonary metabolism and edema, and lactate metabolism. ...

New Discovery of Key Difference in Bile Acid Metabolism in Patients with Type 2 Diabetes May Suggest Underlying Disorder

... have discovered a key difference in bile acid metabolism in people with type 2 diabetes which may suggest ... important signaling molecules that regulate the metabolism of glucose, fat, and energy. And until now, there ... data suggesting alterations in bile acid metabolism in people with type 2 diabetes. Now new data ...

Amylin Pharmaceuticals Initiates Phase 2B Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment in Obesity

... is a fundamentally important hormone in energy metabolism with a unique role in inducing fat-specific ... a fundamental role in the regulation of energy metabolism and body weight. Amylin acquired exclusive rights ... activities leverage the company's expertise in metabolism to develop potential therapies to treat diabetes ...

Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced

... of baseline within three to six months). Brain metabolism (Additional, Observational Finding) Dr. Lisa ... S/D and GAMMAGARD LIQUID treatment. "Brain metabolism usually decreases progressively in patients ... The Phase II study also evaluated brain metabolism in patients treated with GAMMAGARD S/D and ...

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Metabolism in Medical Products

Cortisol RIA Test

Description:... glucose counter-regulation, vascular tone, substrate utilization and bone metabolism [1,2,3]. Cortisol is excreted in urine in an unbound (free) form. Cortisol ... 1975. Chernow B, et al. Arch Intern Med 147:1273-1278, 1987. Crapo L. metabolism 28:955-977, 1979. Lee PDK, et al. Pediatrics 76:437-444, 1985. Leisti ...
Company:Diagnostic Systems Laboratories, Inc.

IGFBP-1, Total IRMA Test

Description:... 1993. Westwood M, et al. J Clin Endocrinol Metab 70:1735-1741, 1994. Conover CA, et al. Diabetes 39:1251-1256, 1990. Lee PDK, et al. metabolism 42:409-414, ....
Company:Diagnostic Systems Laboratories, Inc.

IGFBP-1, Total ELISA Test

Description:... 1993. Westwood M, et al. J Clin Endocrinol Metab 70:1735-1741, 1994. Conover CA, et al. Diabetes 39:1251-1256, 1990. Lee PDK, et al. metabolism 42:409-414, ....
Company:Diagnostic Systems Laboratories, Inc.

Calcitonin IRMA Test

Description:... variety of other malignancies, possibly due to ectopic calcitonin production [4]. Copp DH. Endocrinology 131:1007-1008, 1992. McLean GW, et al. metabolism 33:790-796, 1984. Saad MF, et al. Medicine 63:319-342, 1984. Schwartz KE, et al. J Clin Endocrinol Metab 49:438-444, ....
Company:Diagnostic Systems Laboratories, Inc.

C-Peptide of Insulin RIA Test

Description:... to the mature insulin molecule. Although the C-peptide of insulin is biologically inactive, it does undergo significant liver or extra-renal metabolism and therefore has a much longer circulating half-life than insulin [1]. In addition, C-peptide assays may be analytically more sensitive than insulin ...
Company:Diagnostic Systems Laboratories, Inc.

C-Peptide of Insulin ELISA Test

Description:... to the mature insulin molecule. Although the C-peptide of insulin is biologically inactive, it does undergo significant liver or extra-renal metabolism and therefore has a much longer circulating half-life than insulin [1]. In addition, C-peptide assays may be analytically more sensitive than insulin ...
Company:Diagnostic Systems Laboratories, Inc.

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Metabolism in Medical Definition

Pathology

... Hypophosphatemia / Hypophosphatasia - Mg 2+ Hypermagnesemia / Hypomagnesemia - Ca 2+ Hypercalcaemia / Hypocalcaemia / Disorders of calcium metabolism Fluid, electrolyte and acid-base balance Electrolyte disturbance - Na + Hypernatremia / Hyponatremia - Acidosis ( Metabolic , ...
Metabolism in Medical Dictionary

Adrenal glands

... hormone s helpful in regulating the body's metabolism . adrenaline ... The adrenal glands are ... hormone s that affect water balance and metabolism in the body. The adrenal glands produce ... a hormone called cortisol , which regulates metabolism and blood pressure . These include ...

Aerobic

... by the body. afterbirth ... aerobic metabolism A chemical process in which oxygen is used to ... Also known as aerobic respiration , oxidative metabolism , or cell respiration . aerobic respiration ... and are likely to do regularly. Studying the metabolism of cancer at the cellular level, Otto Warburg, ...

Diabetes mellitus

... diabetes mellitus A disorder of carbohydrate metabolism resulting from insulin deficiency . ... chronic disorder of glucose ( sugar ) metabolism caused by inadequate production or use of ... to absorb glucose , necessary for cellular metabolism and energy production. Pregnancy Diabetes ...

Endocrinology

... p171 ... Di vision of Endocrinology and metabolism , Johns Hopkins Hospital , Baltimore, MD, and ... article Journal of Clinical Endocrinology and metabolism ANZAC Research Institute FPA (formerly the ... Matthew I. Kim, MD - Endocrinology & metabolism Last Updated: October 3, 2005 ... ...

Gland

... organ in the body. The hormone also regulates metabolism , which explains why people with an underactive ... how fast the body converts food into energy ( metabolism ). Parathyroid hormone , or PTH , is produced ... the neck produces hormone s that help control metabolism . With aging , the thyroid often becomes lumpy ...

Inborn errors

... Inborn errors of metabolism Definition: Inborn errors of metabolism are rare genetic disorders in which the body ... ) normally. Many of the inborn errors of metabolism in young infants cause symptoms such as ...

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Metabolism in Biological News

From the glass to the brain in 6 minutes

... in the Journal of Cerebral Blood Flow and metabolism . metabolism of brain cells affected The brain reacts ... Armin Biller of the working group for cerebral metabolism at the Department of Neuroradiology at Heidelberg ...

Researchers engineer metabolic pathway in mice to prevent diet-induced obesity

... in the June 3 issue of the journal Cell metabolism , chemical and biomolecular engineering professor ... pathway in mice that increased fatty acid metabolism and resulted in resistance to diet-induced obesity. "When we looked at the fatty-acid metabolism issue, we noted there are two aspects of the ...

Toward a systems biology map of iron metabolism

... to the survival of animal cells. When iron metabolism goes wrong the consequences can be devastating. ... researchers with a systems biology map of iron metabolism that would allow scientists to investigate ... "To build the systems biology map of iron metabolism described in this paper we have used the program ...

LSUHSC student awarded top national honor for diabetes research

... Mead Johnson Research Award in Endocrinology and metabolism by the American Physiological Society at the 2009 ... for research in the area of Endocrinology and metabolism at the Experimental Biology Meeting. She works in ... to Ang-(1-7)-mediated restoration of glucose metabolism in diabetic mice." She will present it on ...

UC Davis bench-to-bedside research: Promising treatment in clinical trials

... he said. The enzyme is involved in the metabolism of arachidonic acid, a key signaling molecule ... focused on s-EH, an important enzyme for the metabolism of arachidonic acid that plays an essential role ... of concept that s-EH inhibition modulates glucose metabolism or blood pressure in patients with impaired ...

Disabling enzyme allows mice to gorge without becoming obese, new study finds

... within fat cells that is a key regulator of fat metabolism and body weight, making it a promising target in ... been that the major players in controlling fat metabolism and body weight were endocrine factors, primarily ... caution that previous discoveries in fat metabolism and appetite regulation have not always ...

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Metabolism in Biological Technology

Accera, Inc. Launches Neuera Pharmaceuticals, Inc.

... where the mechanism of defective energy metabolism or hypometabolism is involved. Neuera ... provide a real world validation of the energy metabolism platform for Neuera Pharmaceuticals' pipeline ... hallmark of Alzheimer's disease. Defective metabolism of glucose has been shown to precede the onset of ...

XenoTech LLC Offers Drug Industry New Metabolite Profiling Services Following Acquisition of Waters Synapt HDMS System

... scientific consultants with in vitro drug metabolism study data to support its clients' drug discovery ... "We enjoy a very strong reputation for drug metabolism research and for our consultative approach to ... accurate mass," said Paul Toren, Director of Drug metabolism and Analytical Chemistry at XenoTech. "We were ...

Orexigen(R) Therapeutics Announces First of Four Phase 3 Trials of Contrave(R) Meets Co-Primary and Key Secondary Endpoints

... the central nervous system regulates appetite and metabolism as well as the mechanisms that limit weight loss ... to control the balance of food intake and metabolism and another designed to control food preference, ... of treatment by reducing appetite, increasing metabolism and allowing the body to continue losing weight ...

Study From the University of Texas M.D. Anderson Cancer Center Demonstrates That AHCC(R) is Safe in Combination With Most Chemotherapeutic Agents

... agents. As most chemotherapy agents undergo metabolism in the body through the CYP450 (Cytochrome P-450) ... same isoenzymes. The results of this in vitro metabolism study indicated that AHCC is not an inhibitor of ... CYP450 2D6 is not a predominant pathway for metabolism of the most commonly used chemotherapy agents. ...

Life at the jolt

... in their daily diet. By linking bacterial metabolism directly with electricity production, the MFC ... fuel cell, but its relevance to bacterial metabolism has been less clear. The next important concept ... studies have shown that the rate of bacterial metabolism at the anode increases when the electrical ...

Amylin Pharmaceuticals Announces Positive Results from Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment for Obesity

... by fat cells that plays a fundamental role in the regulation of energy metabolism and body weight. To date, more than 1,200 overweight or obese individuals ... research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is ...

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Metabolism in Biological Products

Metabolic Profiler from Bruker Daltonics

Description:... Bruker Daltonics and Bruker BioSpins Metabolic Profiler is an integrated platform for metabolism studies, and analysis of complex mixtures. It features an HPLC-microTOF ESI-TOF system, an optional Avance NMR spectrometer and integrated software ...
Company:Bruker Daltonics

NanoMate ™ 100 with ESI Chip Technology from Advion Biosciences, Inc.

Description:... to either speed analysis for increased throughput for small molecule and peptide mapping applications, or long acquisition times for proteomics and metabolism applications where greater sample information is needed. Company:Advion Biosciences, Inc.

Osteoclasts Culture Kit from B-Bridge International

Description:... (OCP) cells from bone marrow and culture medium containing M-CSF and RANKL for researchers studying osteoporosis, bone reabsorbtion, or other bone metabolism ....
Company:B-Bridge International

Rabbit Anti-Mint3 Polyclonal Antibody, Unconjugated from ABR-Affinity BioReagents

Description:... suggested that mint3 links APP to other transport machinery components, thereby regulating it transport, endocytosis, and metabolism. Abnormal APP metabolism has been shown to be the cause of an early-onset type of Alzheimers ....
Company:ABR-Affinity BioReagents

LTQ XL Linear Ion Trap from Thermo Scientific

Description:... MSn performance of the LTQ linear ion trap with powerful new tools to generate extensive structural information for the most demanding proteomics and metabolism applications. Multiple dissociation techniques (PQD, ETD, CID) Extensive coverage for predicted and unpredicted metabolites Fast ...
Company:Thermo Scientific

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Metabolism in Biological Definition

Cell metabolism

... Cell metabolism is the process (or really the sum of many ... nutrient molecules and maintain a living state. metabolism has two distinct divisions: anabolism , in which ... to yield energy and reducing power. Cell metabolism involves extremely complex sequences of ...

Glycolysis

... O + 2 H + So, for simple fermentations, the metabolism of 1 molecule of glucose has a net yield of 2 ... reactions more closely connected to aerobic metabolism occur). Glucose gets into the cell through ... oxidative phosphorylation . Although human metabolism is primarily aerobic, under anaerobic conditions, ...

Insulin

... hormone that regulates carbohydrate metabolism . Apart from being the primary effector in carbohydrate homeostasis, it also takes part in the metabolism of fat ( triglycerides ) and proteins – ... slightly between species . Its carbohydrate metabolism regulatory function strength also varies. Pig ...

Life

... once during its existence : Growth metabolism , consuming, transforming and storing energy / ... of life can be simply remedied by defining metabolism in a more biochemically exact way. Biochemistry by Voet and Voet defines metabolism as follows: "Metabolism is the overall process ...

Metabolism

... metabolism (from ... ( anabolism ) and their breakdown ( catabolism ). metabolism usually consists of sequences of enzymatic steps, also called metabolic pathways . The total metabolism are all biochemical processes of an organism. ...

Origin of life

... is regarded as moving force of early evolution (" metabolism -first"). Recently, trends are emerging to create ... and postulate the emergence of a primitive metabolism which could provide an environment for the later ... for the plausibility of the emergence of metabolism without the presence of genes include a ...

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Metabolism in Biological Dictionary

Pyrimidine

... v • d • e ... Nucleotide metabolism: Purine metabolism · Nucleotide salvage · Pyrimidine metabolism ... Pyrimidine Catabolism. De novo ... New and used books like Purine and Pyrimidine metabolism in Man X Advances in ... ...

Metabolism

... metabolism is the set of chemical reactions that occur in ... structures, and respond to their environments. metabolism ... metabolism n. The chemical processes occurring within a ...

Insulin

... is a hormone which has extensive effects on metabolism and other body functions, such as vascular ... and functioning in the regulation of the metabolism of carbohydrates and fats, Establishes the ... is a hormone which has extensive effects on metabolism and other body ... File:Suckale08 fig3 glucose ...

Cell metabolism

... metabolism is the set of chemical reactions that occur in ... structures, and respond to their environments. metabolism ... The cell is the structural and ... such as ... The online version of Cell metabolism on ScienceDirect, the world's leading ... ...

Catabolism

... oxygen relationships can be found here. ... metabolism chemistry, inclusive term for the chemical ... ... Introduction; Anabolism and Catabolism ; How metabolism Derives Its Energy; Food ... Get information, ... - Definition. Anabolism is the aspect of metabolism that contributes ... Catabolism : Catabolic ...

Biotin

... and Biotin is a vitamin that aids in the metabolism of food. ... When normal intake of biotin is ... B vitamin, acts as a coenzyme in the metabolism of protein, fats, and carbohydrates. ... dietary ... B vitamin, acts as a coenzyme in the metabolism of protein, fats, and carbohydrates. ... dietary ...

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