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mediated in Medical News

Bariatric Surgery Cuts Cancer Risk for Women

... bariatric surgery could not be demonstrated to be mediated by weight loss or reduced energy intake." New ... women. If the favorable effect in women is not mediated by weight loss or reduced energy intake, it must be mediated by something else," he said. Andrew G. ...

JCI table of contents: June 20, 2008

... Cigarette smokeinduced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 ... tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins AUTHOR ... analysis revealed that the HDAC inhibitors mediated their effects by inducing DCs to express more of ...

The immune system's role in hepatitis C recurrence after liver transplantation

... the model that a genetic component contributes to natural killer cell mediated control of virus as well natural killer cell mediated hepatic injury in the setting of liver transplantation for HCV." ...

UCLA Art/Sci Center to host symposium on sound and science

... day of the symposium will feature presentations related to technologically mediated forms of listening from the nanoscale of cells to the macroscale of solar winds and similarly mediated modes of musical expression. The field of acoustic ecology will also be ...

2 immune-system proteins linked to colitis-associated cancer

... during CAC development, and that its molecular effects are largely mediated by the transcription factor STAT3 in cancer cells. Their latest study ... Karin said. The proliferative and survival effects of IL-6 are largely mediated by the transcription factor STAT3, first suggested to have a ...

Novel Photoconductive Cellular Depolarization Technology Reveals Insight Into Neuronal Growth, Guidance, and Regeneration

... this, researchers have sought to better understand how axon guidance is mediated in order to potentially aid in recovery following injury. Focusing ... axon guidance in which growth guidance both spatial and temporal is mediated by neuronal activity. Further under experimental conditions simulating ...

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mediated in Medical Technology

Pharmacyclics Announces Data and Publication Characterizing Highly-Selective HDAC Inhibitor

... play a role in T-cell lymphoma and other immune mediated diseases. "To our knowledge, this is the first ... developing may be useful in addressing diseases mediated by T-cells such as T-cell lymphomas or certain ... innovative products to treat cancer and immune mediated diseases. The company is leveraging its ...

Novavax Announces Top Line Results of Phase IIa Clinical Trial for Its Seasonal Influenza VLP (Trivalent) Vaccine Candidate

... inducing not only anti-HA responses but also anti-neuraminidase and cell mediated immune responses. We believe these attributes of the VLP vaccine may ... tract, potentially reducing the severity of influenza disease; and cell mediated immune responses to M1 may lead to destruction of cells already infected. ...

Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting

... The study showed that larazotide acetate inhibited increased permeability mediated with TNF-alpha and IL-4, which suggests the potential of larazotide ... and commercialization of therapies to treat auto-immune, immune mediated and inflammatory diseases and is located in Baltimore, Maryland. ...

SARcode and Sunesis Announce Start of Phase 1 Clinical Trial in Ocular Inflammatory Diseases

... 1 clinical trial of a small molecule LFA-1 product candidate for T-cell mediated ophthalmic diseases. Sunesis and SARcode entered into a license agreement ... immunomodulators/ anti-inflammatory agents for the treatment of T-cell mediated inflammatory diseases. About Sunesis Pharmaceuticals Sunesis is a ...

DG041 Blocks Platelet Aggregation Through a Novel Mechanism and does not Increase Bleeding Time When Given Alone or with Plavix(TM) or Aspirin

... out of this study is that DG041 was shown to substantially inhibit EP3 mediated platelet activation that is not being addressed by current therapy. This ... dramatically inhibit platelet aggregation as well as platelet activation mediated specifically through vasodilator-stimulated phosphoprotein (VASP), a ...

Pharmacyclics Novel Btk Inhibitor Shows Efficacy in Preclinical Models of Rheumatoid Arthritis and Lymphoma

... promise for potential use in humans with advanced RA and other immune mediated diseases. The inhibition of B-cell function and proliferation in the ... and inhibition of its function may be useful in the treatment of immune mediated diseases. Mast cells play a key role in the inflammatory process and are ...

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mediated in Medical Products

Vasopressin (AVP) RIA Test

Description:... and exercise [1]. The primary function of AVP is the regulation of water permeability of the renal collecting tubules and ascending loop of Henle. mediated through activation of cAMP, the effect of AVP is to allow the kidney to reabsorb water and concentrate urine [1]. At high plasma concentrations, AVP ...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, w/ Extraction IRMA Test

Description:... is secreted primarily by the liver and is postulated to have mitogenic and metabolic actions involved in cellular growth. The actions of IGF-II are mediated by binding to target cell receptors. IGF-II binds with high affinity to the Type II IGF receptor, a monomeric protein which also serves as the ...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, w/ Extraction ELISA Test

Description:... is secreted primarily by the liver and is postulated to have mitogenic and metabolic actions involved in cellular growth. The actions of IGF-II are mediated by binding to target cell receptors. IGF-II binds with high affinity to the Type II IGF receptor, a monomeric protein which also serves as the ...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, Non-Extraction IRMA Test

Description:... is secreted primarily by the liver and is postulated to have mitogenic and metabolic actions involved in cellular growth. The actions of IGF-II are mediated by binding to target cell receptors. IGF-II binds with high affinity to the Type II IGF receptor, a monomeric protein which also serves as the ...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, Non-Extraction ELISA Test

Description:... is secreted primarily by the liver and is postulated to have mitogenic and metabolic actions involved in cellular growth. The actions of IGF-II are mediated by binding to target cell receptors. IGF-II binds with high affinity to the Type II IGF receptor, a monomeric protein which also serves as the ...
Company:Diagnostic Systems Laboratories, Inc.

hGH IRMA Test

Description:... while the amplitude of GH release is determined by GHRF. GH has profound effects on tissue growth and metabolism, which is thought to be mediated through GH-dependent production of IGF-I and IGF-II, and their associated binding proteins. GH apparently stimulates IGF production after binding to ...
Company:Diagnostic Systems Laboratories, Inc.

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mediated in Medical Definition

Depolarization-induced suppression of inhibition

... way of producing an in vitro endocannabinoid mediated effect. DSI is classically produced in a brain ... After the depolarization, inhibitory GABA mediated neurotransmission is reduced. This has been ... to GABA during DSI. Somehow, DSI appeared to be mediated by a retrograde synaptic messenger whose ...

Blind loop syndrome

... 4 Signs and tests 5 Treatment Physiology The obstruction of a section of intestine causes ineffective bile salt mediated digestion of fats, causing fatty stools and poor absorption of fat and fat-soluble vitamins. Vitamin B12 deficiency may occur because the increased ...

Therapeutic gene modulation

... protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly. Modulation of gene expression can be mediated at the level of transcription by artificial transcription factors or at the level of translation through RNA interference . See also ...

Thymocyte

... the thymus showing the cortex and medulla Minute structure of thymus. The ability of T cells to recognise foreign antigens is mediated by the T cell receptor , which is a surface protein able to recognise short protein sequences ( peptides ) that are presented on MHC . During the ...
mediated in Medical Dictionary

Cell

... and nonseminoma germ cell tumor s. Usually testicular cancer occurs only in one testicle. Cell biology Research Interest: Exocytosis is mediated by transport, docking, and fusion of secretory vesicles carrying protein s and lipid s to defined areas of the plasma membrane . CELL ...

Chronic

... Ulcerative Colitis (CUC) Ulcerative Colitis An inflammatory disease of the large bowel . It is not an allergic disease because is not mediated by IgE , but has an immunologic basis. See also Crohn Disease and Celiac Disease . Home ... Chronic lymph ocytic leukemia , which is also ...

Colitis

... Ulcerative Colitis (CUC) Ulcerative Colitis An inflammatory disease of the large bowel . It is not an allergic disease because is not mediated by IgE , but has an immunologic basis. Colitis An inflammatory disease , colitis affects the colon (large intestine ), the lower portion ...

Complement

... s in the blood that influence the inflammatory process and serve as the primary mediator in antigen - antibody reactions of the B cell mediated immune response . Components of complement are labeled C1 - C9. Complement system: A series of molecules that work together to perform many ...

Diagnose

... d. Mandatory reporting is required for AIDS in all 50 states. Most cases of extrinsic asthma have an allergic origin and are caused by an IgE mediated response to an inhaled allergen . This is the type of asthma commonly diagnose d in early life. Many patients with extrinsic asthma may ...

Hypotension

... when it's known as postural or orthostatic hypotension . Experimental therapies - When patients with chronic fatigue syndrome have neurally mediated hypotension , they may benefit from treatment with fludrocortisone (Florinef), beta -adrenergic blocking agents and other medications. ...

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mediated in Biological News

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

... complex mental functions such as thinking, learning, memory or emotion is mediated by a large number of chemical neurotransmitters and neuromodulators. ... minimising adverse events. For instance, the signalling of serotonin is mediated by 14 receptor subtypes. As one of the main mediators of the ...

Potential new therapeutic molecular target to fight cancer

... potent lipid mediator sphingosine-1-phosphate in the death of cancer cells mediated by the chemotherapeutic drug, doxorubicin. Doxorubicin is able to kill ... p21 regulates the cell cycle, and apoptosis or programmed cell suicide, mediated by doxorubicin. Human colon and breast cancer cells were killed more ...

Ultra-low-dose aspirin might decrease bleeding severity in portal hypertension

... cell alterations and bleeding time. Further, this effect is mediated by Cyclooxygenase 2 inhibition. This study, performed by a team led ... shown that the prothrombotic properties of ultra-low-dose aspirin are not mediated by platelets but by endothelial cells, and as such they have the potential ...

Stem cell research: From molecular physiology to therapeutic applications

... properties of stem cells and developing nonhuman primate models for stem cell-based therapy of degenerative diseases. He has developed a stem cell mediated expression system for treating Parkinson's disease and his research using pancreatic progenitor cells for treating diabetes has demonstrated efficacy ...

The SIB recognizes the next generation of bioinformaticians

... of protein sequences. A key feature of the method is that it is able to disentangle direct interactions from indirect interactions that are mediated via other residues. As such the method greatly improves the prediction of contacting amino acids in the 3-dimensional structure of proteins and is ...

One size does not fit all

... of MS, allowing MNI researchers to determine the direct effect of long-term statin therapy on remyelination, independent of its indirect effects mediated via immune modulation. "The results of our study indicate that simvastatin has in fact, a slightly deleterious effect on myelin under ...

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mediated in Biological Technology

Pharmacyclics to Present at the 8th Annual Needham and Company Life Sciences Conference

... innovative small molecule drugs for the treatment of immune mediated disease and cancer, today announced that Glenn Rice, President and COO ... innovative small-molecule drugs for the treatment of immune mediated disease and cancer. The purpose of the company is to create a profitable ...

BioCryst Reports Fourth Quarter and Year End 2008 Financial Results and Provides Corporate Update

... support the evaluation of BCX-4208 in the treatment of not only T-cell mediated diseases, but also B-cell mediated diseases. Corporate Developments Stanley ...

Pharmacyclics, Inc. Rights Offering Oversubscribed

... is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative small-molecule drugs for the treatment of immune mediated disease and cancer. The purpose of the company is to create a profitable business by generating income from products it develops, licenses and ...

DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD

... is an inflammatory disease initiated by T cells in the donor graft that recognize histocompatibility and other tissue antigens of the host, and is mediated by a variety of effector cells and inflammatory cytokines. GVHD presents in both acute and chronic forms. The symptoms of cGVHD typically present at ...

Novavax Announces Selection of a Respiratory Syncytial Virus Vaccine Candidate for Advanced Preclinical Studies

... of the native virus. The particle nature of the vaccine holds the promise for inducing a broad set of immune responses including antibody and cell mediated immune responses to prevent infection of the respiratory tract and attack respiratory cells that may already be infected with RSV. The ...

Pharmacyclics Announces Subscription Price for Rights Offering

... is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative small-molecule drugs for the treatment of immune mediated disease and cancer. The purpose of the Company is to create a profitable business by generating income from products it develops, licenses and ...

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mediated in Biological Products

Mouse Anti-67kD Laminin Receptor Prediluted Monoclonal Antibody, Unconjugated, SPM278 from GeneTex

Description:... species. Background Information Laminin, one of the major glycoproteins of basement membrane, displays multiple biological activities which are mediated through its interaction with specific cell membrane receptors. Overexpression of Laminin Receptor is reportedly an independent prognostic factor in ...
Company:GeneTex

GenoStat Inducible Expression System from Upstate

Description:... regulated control of exogenous gene expression in mammalian cells and is capable of repeated on/off expression kinetics. This degree of control is mediated by the highly specific interaction between the GenoStat Ligand and the chimeric bipartite nuclear receptor complex. Gene expression levels are easily ...
Company:Upstate

Phagocytosis Fluorometric (dichlorofluorescein) Assay Kit, OxyBURST from Molecular Probes (Invitrogen)

Description:... Green reagent (F-2902) was developed in collaboration with Elizabeth Simons of Boston University to permit measurement of the kinetics of Fc receptor mediated internalization and the subsequent oxidative burst directly in the phagovacuole.2 The Fc OxyBURST Green assay reagent consists of bovine serum ...
Company:Molecular Probes (Invitrogen)

Mouse Anti-HDAC8 Monoclonal Antibody, Unconjugated, Clone HDAC8-48 from GeneTex

Description:... Mouse monoclonal [HDAC8-48] to HDAC8 Regulation of gene expression is mediated by several mechanisms such as DNA methylation, ATP-dependent chromatin remodeling, and post translational modifications of histones, which include ...
Company:GeneTex

Mouse Anti-p14 ARF / p16Beta Ab-2 Mouse Monoclonal Antibody, Unconjugated, Clone 14P02 from Lab Vision

Description:... promotes the rapid degradation of mdm2 proteinrequired for mdm2 modification and concurrent p53 stabilization and accumulation. This interaction is mediated by the exon 1Beta-encoded N-terminal domain of p14^ARF^ and a C-terminal region of mdm2. Deletion of the ARF-INK4a locus simultaneously impairs both ...
Company:Lab Vision

FRT flanked, Pro and Euk. Neomycin Selection Cassette plus loxP site(FRT-PGK-gb2-neo-FRT-loxP) from Gene Bridges GmbH

Description:... sites can be introduced by adding the corresponding sequence in the PCR primer. The template can easily be used to generate targeting constructs mediated by Red/ET Recombination. The FRT-PGK-gb2-neo-FRT-loxP template is not linear but plasmid based (3485 bp in size). Due to its R6K origin the plasmid ...
Company:Gene Bridges GmbH

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mediated in Biological Definition

Enzyme

... Structure and function 2.1 Rate of enzyme mediated reactions 2.2 Specificity 2.3 Kinetics ... reactions in one direction. Rate of enzyme mediated reactions Main article: Rate of enzyme mediated reactions Enzymes can increase reaction rate ...

Michaelis-Menten kinetics

... kinetics describe the rate of enzyme mediated reactions for many enzymes. It is named for ... To determine the maximum rate of an enzyme mediated reaction, the substrate concentration ( [S] ) ... , the factors that effect the rate of enzyme mediated reactions (ie. pH, temperature, etc) are at ...

Active transport

... Active transport is the mediated transport of biochemicals , and other atomic / molecular substances, across membranes . Unlike passive transport , this process requires ...

Dendrite

... that action potentials do propagate back into the dendrites once initiated in the axon in most neurons. This backpropagating action potential is mediated by the activation of voltage-gated ion channels and can interact with synaptic input to alter the synaptic activity. The structure and branching of ...

Facilitated diffusion

... ) is a process of passive transport ( diffusion ) via which molecules diffuse across membranes , with the help of transport proteins ( mediated transport ). Small uncharged molecules can easily diffuse across cell membranes. However, due to the hydrophobic nature of the lipids that make ...

Neuron

... thousands of other cells. Types of signalling Neurons communicate with one another across synapses. This communication is usually chemically mediated by rapid secretion of neurotransmitter molecules . Pre-synaptic neurons (i.e.the neurons which release the neurotransmitter) may produce in the ...

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mediated in Biological Dictionary

Humoral immunity

... (HIR) is the aspect of immunity that is mediated by secreted antibodies produced in the cells ... Immunity ... Humoral immunity is that mediated by antibodies. ... For humoral immunity , an ... to Common Viral and Vaccine Antigens Cell mediated and Humoral Immunity . The body's Humoral ...

Cell-mediated immunity

... Cell - mediated immunity is an immune response that does not ... immunity ... Aspects of the topic cell - mediated - immunity are discussed in the following places ... participate ... ... Immunity . Cell - mediated Immunity . Humoral ... but sensitized in the ...

Active transport

... Active transport is the mediated process of moving particles across a biological ... ... Description: Active transport is the mediated process of moving ... active ... Active ... just passively ... Active transport is the mediated process of moving particles across a biological .....

Trans-splicing

... of genetic information in ... Cis- and trans - splicing of mRNAs mediated by ... Trans - splicing Trans - splicing is a special form of RNA ... a modification of an RNA after ... Cis- and trans - splicing of mRNAs mediated by tRNA sequences in eukaryotic cells". Proc. ... leader RNA was tested ...

Tet resistance

... the Tet (B) antiport protein.Antimicrob. ... tetracycline resistance mediated by hybrid Tet proteins. ... ... tetracycline resistance ... . Resistance to the TET for gram-neg and gram-pos bacteria is mediated by ... Absorption of TET is impaired by food in the stomach, milk ...

Endocytosis

... Verlag|Plant Cell Monographs, 1|Jozef ... Receptor mediated endocytosis is a process by which cells internalize ... How does receptor mediated endocytosis reduce our serum levels of cholesterol? ... There are ...

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Other Contents
(Date:12/21/2014)... San Francisco, California (PRWEB) December 21, 2014 ... announces his search for Vintage 1967 Jm Morrison and the ... D.C. concert posters. This would also be the only ... live. The concert was on Nov. 25, 1967. According ... in Washington D.C. They did play the Alexandria Roller ...
(Date:12/21/2014)... 2014 Over the past 39 years, ... hundreds of emergency departments across the nation, from quality ... been translated into an innovative suite of tools, systems, ... and enhance the patient experience. , NES Health, ... and management services for hospitals, announced the development and ...
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(Date:11/21/2014)... , November 18, 2014 According ... Market by Systems (Video, RFID, Access Control, Intrusion Detection, ... Hotels, Banks, Government), Component Service Geography - Global Forecasts ... Market is projected to be around $25 Billion in ... 2020, growing at a CAGR of 8.69%. ...
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