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Marrow in Medical News

PET can help guide treatment decisions for a common pediatric cancer

... of all of these treatments along with bone marrow transplant or investigational therapies. In ... a combination of chemotherapy, surgery, bone marrow transplant and investigational therapies. In ... to treatment of tumor in the bone or bone marrow more accurately. ...

UF scientists program blood stem cells to become vision cells

... of Florida researchers were able to program bone marrow stem cells to repair damaged retinas in mice, ... implies that blood stem cells taken from bone marrow can be programmed to restore a variety of cells ... removed blood stem cells from the bone marrow of mice, modified the cells in cultures, and ...

Leukemia cells evade immune system by mimicking normal cells, Stanford studies show

... were also temporarily elevated in healthy bone marrow stem cells migrating to organs like the spleen or ... response to infection or inflammation, or to bone marrow sites to replenish missing stem cells. A closer ... power is exemplified by the fact that mouse bone marrow stem cells lacking CD47 and thus vulnerable to ...

Cerebral Palsy Improves After Bone Marrow Stem Cell Procedure

... consisted of removing 300 milliliters of bone marrow from her hip and giving it back to her intravenously. Five hours after the raw bone marrow infusion, E.H. was able to move her right toe for ... treatments. Contained within a patient's own bone marrow are stem cells, which when given back to the same ...

Cell transplantation and cardiac repair

... research team who looked at two different bone marrow cell delivery methods following myocardial ... a team of researchers in Germany who used bone marrow stem cell transplants to repair limb ischemia ... Bone marrow cell transplants for limb ischemia ...

First Human Receives Cardiac Stem Cells in Clinical Trial to Heal Damage Caused By Heart Attacks

... modest improvement when treated with bone marrow stem cells. However, bone marrow stem cells are not predestined to regenerate ... and then multiplying the cells. Unlike bone marrow cells, heart stem cells are naturally programmed ...

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Marrow in Medical Technology

British Woman Celebrates a Year of Living Cancer-Free

... treatments, including chemotherapy and a bone marrow transplant, failed to keep her in remission. Ms. ... multiplied. Within a month, a study of her bone marrow -- the site affected by the type of leukemia she ... abnormal white blood cells accumulate in the bone marrow and impede the production of normal blood cells. ...

UPCI Joins ExCell Research Study Using Stem Cells for Leukemia and Lymphoma Patients

... stem cells, as an alternative treatment to bone marrow transplants for hematological malignancies, ... blood stem cells instead of a traditional bone marrow transplant opens tremendous ... diseases like leukemia and lymphoma." Bone marrow transplantation is a life-saving treatment for ...

Bayer Announces Leukine(R) Data Presentations at 45th American Society of Clinical Oncology (ASCO) Annual Meeting

... following allogeneic and autologous bone marrow transplantation (BMT), peripheral blood stem cell ... patients undergoing PBSC transplantation and bone marrow transplantation failure or engraftment delay. ... patients with excessive leukemic blasts in bone marrow or peripheral blood (10 percent), in patients ...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

... mediate the cells' ability to home to the bone marrow and eventually repopulate the patient's blood and ... with HSCs from any source, including from bone marrow and peripheral blood. FT1050 was discovered by ... of HSCs is necessary to restore normal bone marrow function. Also the immune cells generated by the ...

Cardium Reports on Applicability of Corgentin to Stem Cell Therapies: Independent Studies Indicate that Ad5IGF-1 Potentiates Stem Cells to Improve Cardiac Function After Heart Attack

... Mesenchymal Stem Cells Accelerate Bone marrow Stem Cell Mobilization via Paracrine Activation ... to massive stem cell mobilization from the bone marrow and their increased homing in the injured heart ... receptor 4 (found on these stem cells in the bone marrow but reduced after ex vivo expansion) with the ...

ViroPharma Announces Discontinuation of Maribavir Phase 3 Study in Liver Transplant Patients

... current therapies, including suppression of bone marrow function. About maribavir Maribavir is a ... or myelosuppression (a condition in which bone marrow activity is decreased, resulting in fewer red ... use is limited by toxicities, most notably bone marrow suppression and renal impairment. About ...

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Marrow in Medical Products

Healos Bone Graft Replacement

Description:... a proprietary 360 accretion process. When combined with autogenous bone marrow aspirate, Healos provides an excellent environment for osteoprogenitor ... recreating the natural human response. The matrix, saturated with bone marrow aspirate, remodels into new bone throughout the graft site, not solely by ...
Company:DePuy Orthopaedics, Inc.

Stat Stain

Description:... Volu-Sol's Stat Stain is ideal for stat, routine or back-up staining. Developed to rapidly stain blood smears (10-15 seconds) and bone marrow (20-30 seconds). Our unique manufacturing process generates finely dispersed stain particles which yield excellent color intensity and morphological ...
Company:Volu-Sol, Inc.

Wright-Giemsa Stain

Description:... This Wright-Giemsa is a dual-use stain for peripheral blood and bone marrow smears. It produces somewhat darker results when compared with Giemsa, particularly in the blue to magenta ....
Company:Richard-Allan Scientific

Wright stain

Description:... Our Wright stain is a dual-use stain for peripheral blood and bone marrow smears. It produces results similar to those of the Giemsa stain with a slightly greater ....
Company:Richard-Allan Scientific

Aerospray Hematology Slide Stainer/Cytocentrifuge

Description:... It offers a truly unique and modern approach to slide staining, ending messy procedures. The instrument of choice for peripheral blood smears, bone marrow and other body fluids. With the optional Cytopro rotor, the Aerospray stainer becomes a superb cytocentrifuge with eight-slide capacity and full ...
Company:Wescor, Inc.

HLA Bone Marrow Transplantation Evaluation

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

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Marrow in Medical Definition

Hematopathology

... see below ). A hematopathologist looks at peripheral blood smears , bone marrow aspirates and biopsies , lymph nodes , and other tissues, and uses ... called the " WHO classification". [1] Leukemias are mainly bone marrow and blood based and can be subclassified as chronic leukemia and ...

Thymocyte

... Thymus Settling Thymocytes are ultimately derived from bone marrow hematopoietic progenitors cells [see hematopoietic stem cell , ... ] ^ Schwarz BA, Bhandoola A. Trafficking from the bone marrow to the thymus: a prerequisite for thymopoiesis. Immunol Rev 209:47, ....

Central tolerance

... self-reactive (recognise the component self antigens of the host). In mammals the process occurs in the thymus (T cells) [2] [3] and bone marrow (B cells), when maturing lymphocytes are exposed to self antigens. Self antigens are present in both organs due to endogenous expression within ...

Pathology

... processes. [8] Inflammation A transmission electron microscope image of an immune cell crossing from the bone marrow into the circulation Inflammation is a particularly important and complex reaction to tissue injury, and is particularly important in ...
Marrow in Medical Dictionary

Acute

... by the presence in the blood and bone marrow of large numbers of unusually immature white ... is a type of cancer of the blood and bone marrow — the spongy tissue inside bones where ... lymphocyte s) are found in the blood and bone marrow . Acute post -streptococcal ...

Acute myelogenous leukemia

... is a type of cancer of the blood and bone marrow — the spongy tissue inside bones where ... cancer of blood -forming tissue s of the bone marrow . It is characterized by the growth of immature ... lymphocyte s) are found in the blood and bone marrow . acute myelogenous leukemia acute ...

Anemia

... , or EPO, which stimulates the bone marrow to produce the proper number of red blood ... genetic disease that affects all of the bone marrow elements, is associated with a great diversity ... fatal inherited disease in which the bone marrow fails to produce red blood cells, white blood ...

Aplastic

... anemia : Anemia due to failure of the bone marrow to produce blood cells, including red and ... Aplastic anemia occurs when the bone marrow produces too few of all types of blood cells: ... anemia is a condition in which the bone marrow fails to produce blood cells. What is going on ...

Aplastic anemia

... anemia : Anemia due to failure of the bone marrow to produce blood cells, including red and ... cause. Aplastic anemia occurs when the bone marrow produces too few of all types of blood cells: ... anemia is a condition in which the bone marrow fails to produce blood cells. What is going on ...

Aspiration

... for removing fluid from a joint . Bone marrow aspiration is the removal of a small amount of bone marrow fluid through a needle inserted into the bone. ... benign or malignant. Haematologist ... bone marrow aspiration (as-per-AY-shun) The removal of a ...

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Marrow in Biological News

Combined stem cell-gene therapy approach cures human genetic disease in vitro

... (FA) genes, the disease often leads to bone marrow failure, leukemia, and other cancers. Even after receiving bone marrow transplants to correct the hematological ... generated from healthy donors. Since bone marrow failure as a result of the progressive decline in ...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

... for the first time that injecting adult bone marrow stem cells into skeletal muscle can repair ... Mesenchymal stem cells are found in the bone marrow and can differentiate into a variety of cell ... death) and fibrotic remodeling, recruited bone marrow progenitor cells and induced myocardial ...

Just in time for spring: Scientists find the cellular on and off switch for allergies and asthma

... mouse experiments that examined cells from bone marrow and umbilical cord blood that ultimately help ... cells, the developing cells die. Because bone marrow makes both mast cells and these cytokines, the ... as the "on switch" for the immune system, bone marrow cells also use them as the "off switch" to stop ...

World premiere in stem cell research in Montreal

... nearly 4,000 people wait in vain for a bone marrow transplant due to the lack of compatible donors. It is known that a bone marrow stem cell transplant can reconstitute the ... these patients will be able to obtain new bone marrow within the next few years. "It could be possible ...

Scientists identify key gene that protects against leukemia

... evidence that could lead to a protocol for bone marrow transplants that could boost the chance of a cure ... ramifications for patients undergoing bone marrow transplants, for leukemia, lymphoma, multiple ... cancers. "Currently, patients undergoing bone marrow transplants may not be getting enough of the ...

CSHL team develops mouse models of leukemia that predict response to chemotherapy

... by additional chemotherapy cycles or bone marrow transplantation. Yet only a quarter of patients ... treated with radiation to destroy existing bone marrow cells. The altered stem cells then took over the "host" bone marrow and promoted the development of leukemia. To ...

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Marrow in Biological Technology

ThermoGenesis Announces Expanded Collaboration With Celling Technologies

... of SpineSmith, LLC, related to the Company's bone marrow products, MXP(TM) MarrowXpress(TM) ("MXP") and ... facilitates cryopreservation of processed bone marrow aspirates. The bone marrow concentrates are used in spinal fusion ....

ThermoGenesis Provides Update on Fiscal 2009 Results

... a point of care processing device for bone marrow aspirate to concentrate stem cells, was formally launched in July. The Res-Q System processes bone marrow in minutes and delivers a high rate of stem cell ... the market adoption of the Company's bone marrow processing technologies and increase Company ...

Celator(R) Pharmaceuticals Presents Data on the Activity of CPX-351 Against Leukemia at the European Hematology Association Congress

... cells but permitted the regrowth of normal bone marrow cells within 42 days of treatment in a Rag2-M ... up in higher levels by leukemic cells in the bone marrow than by normal bone marrow cells. They concluded that the preferential ...

Kiadis Pharma Reports ATIR(TM) Clinical Data, Further Supporting its Potential in Mismatched Bone Marrow Transplantations

... ATIR(TM) showing its potential in mismatched bone marrow transplantations. Data was presented by ... Symposium at the Annual European Bone marrow Transplantation meeting (EBMT) in Goteborg, ... for early immune reconstitution following a bone marrow transplantation with a fully mismatched ...

ThermoGenesis Announces Abstracts to Be Presented at Upcoming Stem Cell Therapy Conference

... the efficiency of stem cell recovery from bone marrow following processing with the MXP and ... reduce and harvest stem cells from human bone marrow in a functionally closed system. Results ... efficient collection of stem cells from bone marrow aspirate and platelet rich plasma from whole ...

DOR BioPharma Appoints Brian L. Hamilton, MD, PhD as Chief Medical Officer

... and Oncology. He began his training in bone marrow transplantation while in medical school, with ... Miami , focused on pediatric immunology and bone marrow transplantation. His research focus was in the ... with a clinical appointment on the Pediatric Bone marrow Transplant Service at the University of ...

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Marrow in Biological Products

CELLection Epithelial Enrich from Dynal Biotech

Description:... the human epithelial antigen EpCAM and DNase Releasing Buffer. For up to 5 log enrichment of epithelial tumour cells directly from blood, bone marrow or MNC. Tumour cells clumps can be enriched from bone marrow. Enriched cells are viable and bead-free and are suitable for immunocytochemical ...
Company:Dynal Biotech

Mouse Hematopoietic Stem Cell Expansion Cytokine Panel from R&D Systems

Description:... self-renewal capacity and are responsible for the life-long maintenance of the hematopoietic system. HSC are rare cells that reside in adult bone marrow where hematopoiesis is continuously taking place. They can also be found in cord blood, fetal liver, adult spleen and peripheral blood. Many HSC ...
Company:R&D Systems

GIBCO MarrowMAX Bone Marrow Medium from Invitrogen

Description:... MarrowMAX Bone marrow ...
Company:Invitrogen

Terminal deoxynucleotidyl transferase (TdT) Immunofluorescence Assay Kit from AbD Serotec

Description:... deoxynucleotidyl transferase (TdT) is an intracellular marker normally present at high levels in cortical thymocytes and minor subpopulation of bone marrow prelymphocytes. Elevated levels of the enzyme and increased numbers of TdT cells are found to be associated with some lymphoblastic leukaemias and ...
Company:AbD Serotec

Osteoclasts Culture Kit from B-Bridge International

Description:... of differentiation in the pre-osteoclast stage. B-Bridges Osteoclast Culture Kit includes cryopreserved osteoclast precursor (OCP) cells from bone marrow and culture medium containing M-CSF and RANKL for researchers studying osteoporosis, bone reabsorbtion, or other bone metabolism ....
Company:B-Bridge International
Marrow in Biological Definition

Bone

... marrow, which is gradually replaced with yellow marrow as the child ages (see Bone Development below). ... cartilage ossifies, fusing the two together. marrow can be found in most any bone that holds ... all such bones are filled exclusively with red marrow , but as the child ages it is mostly replaced by ...

Stem cell

... can transform into several different forms. Bone marrow stromal stem cells are known to be able to ... Current treatments For over 30 years, bone marrow (adult) stem cells have been used to treat ... is terminated, the stem cells in the bone marrow produce large amounts of red and white blood ...

Cancer

... e.g. skin , digestive tract or glands . Leukemia starts in the bone marrow stem cells . Lymphoma is a cancer originating in lymphatic tissue . ... people. Examples include: bladder carcinoma , blood (and bone marrow ) - hematological malignancies , leukemia , lymphoma , Hodgkin's ...

B cell

... is an organ unique to birds, where B cells mature. It does not (as commonly assumed among immunologists researching mammals) stand for bone marrow , where B cells are produced in all other vertebrates. The human body makes hundreds of different types of B cells, and each type has a unique ...

Blood

... adapted to the architecture of the blood vessels. Physiology of blood Production and degradation Blood cells are produced in the bone marrow ; the process is termed hematopoiesis . The proteinaceous component is produced overwhelmingly in the liver , while hormones are produced by the ...

Carnivore

... primarily on a diet consisting only of meat. They may consume other products presented to them, especially animal products like cheese and bone marrow , or sweet sugary substances like honey and syrup , but do not need to consume these on a regular basis. True carnivores lack the physiology ...

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Marrow in Biological Dictionary

Bone cell

... cell : A distinct phenotype? ... Bone marrow stromal stem cells : nature, biology, and ... specific heart repair cells from the bone marrow to the injured heart ... Bone marrow Cells Help Repair Damaged Lung (Jan. 27, 2009) ...

B cell

... Any of the lymphocytes that mature in the bone marrow and, when stimulated by a particular antigen, ... B cells are not only produced in the bone marrow but also mature there. ... The bound antigen ... in the fetal liver and continues in the bone marrow ... You'll find interesting information on how ...

Vessel cell

... rather than ... We need a blood vessel cell . ... Universal bone marrow cell spurs growth of vessels and heart muscle. November 10, 2003 ... stem cell clone" found in adult bone marrow regenerated blood vessels and ... Water tends to move into the cell ...

T cell

... T Cells ... However, the precursors of T cells leave the bone marrow and mature in the ... gamma/delta (γδ) T cells . ... Every effective ... thymus; it ... However, the precursors of T cells leave the bone marrow and mature in the ... the T cell receptor (TCR) respectively. Both ...

Plasma cells

... B-cell (not the T-cell) ... Plasma cells are present mainly in bone marrow and lymph nodes. ... These abnormal plasma cells and the antibodies ... ... The overabundance of these cancerous plasma cells in the bone marrow leads to ... In addition, the abnormal plasma cells almost always ...

Neutrophils

... see: Neutrophile. Neutrophils do not normally exit the bone marrow until maturity but during an ... Neutrophils , central cells in acute ... be signaled to leave the ... Production of neutrophils in the bone marrow is also affected by a severe ... Certain rare hereditary diseases also ...

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