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Mantle in Medical News

Millennium Pharmaceuticals Inc./Lymphoma Research Foundation funds lymphoma research

... which are rare diseases. A member of LRF's mantle Cell Lymphoma Consortium (MCLC), Dr. Fu's work will focus on mantle cell lymphoma (MCL), an aggressive malignant B-cell form of non-Hodgkin lymphoma (NHL). mantle cell lymphoma is a rare form of NHL accounting ...

Pitt, Berkeley researchers reconstruct seashells to model nervous system function

... with a mollusk's tongue-like organ called a mantle and leads to the cells that produce the shell and ... shells, they retrace their previous work with the mantle and use those "memories" to continue the pattern. ... the neurons connecting the sensing cells in the mantle with the secretory cells that produce calcium ...

Data on VELCADE(R) (Bortezomib) for Injection Based Therapies to be Presented at the International Myeloma Workshop

... is indicated for the treatment of patients with mantle cell lymphoma who have received at least one ... of peripheral neuropathy has not been studied in mantle cell lymphoma. Acute development or exacerbation ... liposome injection] study) and previously treated mantle cell lymphoma (N=155) were integrated and ...

Intense chemotherapy wards off recurrence in half of mantle cell lymphoma patients after seven years

... SAN FRANCISCO - More than half of younger mantle cell lymphoma patients who received an intensive ... necessary as a first treatment in newly diagnosed mantle cell lymphoma." mantle cell lymphoma is one of the most lethal versions ...

Novel treatments show improvements in survival and response rates for leukemia and lymphoma

... lymphocytic lymphoma (11 patients), mantle cell lymphoma (nine patients), MALT lymphoma ... lymphocytic lymphoma, 11 percent of mantle cell lymphoma patients, and 10 percent of those ... with diffuse large B-cell lymphoma, four with mantle cell lymphoma, two with chronic lymphocytic ...

Novel Treatments Demonstrate Improvements in Overall Survival and Response Rates in Difficult-To-Treat Forms of Leukemia and Lymphoma

... lymphocytic lymphoma (11 patients), mantle cell lymphoma (nine patients), MALT lymphoma ... lymphocytic lymphoma, 11 percent of mantle cell lymphoma patients, and 10 percent of those ... with diffuse large B-cell lymphoma, four with mantle cell lymphoma, two with chronic lymphocytic ...

Researchers aim to over-stress already taxed mantle cell lymphoma cells

... can disrupt the over-stressed assembly line of mantle cell lymphoma and possibly similar cancers such ... mechanism for eliminating poorly made ones. mantle cell lymphoma, an aggressive cancer of the ... sink won't work with a clogged garbage disposal, mantle cell lymphoma cells will start backing up. When a ...

VCU Massey Cancer Center spearheads novel clinical study for lymphoma patients

... patients with diffuse large B-cell lymphoma, or mantle cell lymphoma. The study is intended for patients ... important classes of new agents." Within the mantle cell lymphoma patient group, the study will ... treatment of patients with relapsed or refractory mantle cell lymphoma, and previously was approved for ...

Incidence of Mantle Cell Lymphoma on Rise

... July 18 (HealthDay News) -- The prevalence of mantle cell lymphoma, an aggressive form of non-Hodgkin ... of Texas M.D. Anderson Cancer Center. mantle cell lymphoma is a fast-growing, incurable cancer ... The study authors found that the incidence of mantle cell lymphoma increased from 2.7 people per one ...

FDA Approves VELCADE(R) (Bortezomib) for Injection for Patients with Previously Untreated Multiple Myeloma

... is indicated for the treatment of patients with mantle cell lymphoma who have received at least one ... peripheral neuropathy has not been studied in mantle cell lymphoma. Acute development or exacerbation ... liposome injection] study) and previously treated mantle cell lymphoma (N=155) were integrated and ...

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Mantle in Medical Technology

Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial

... affecting the immune system, such as DLBCL, mantle cell lymphoma and follicular lymphoma(2). Up to ... lymphoma, Hodgkin's disease, follicular lymphoma, mantle cell lymphoma, DLBCL and small lymphocytic ... disease (53% ORR), follicular lymphoma (50% ORR), mantle cell lymphoma (32% ORR), DLBCL (30% ORR) and ...

Continued Overall Survival Advantage Reported From Pivotal Trial of VELCADE(R) (Bortezomib) for Injection Based Therapy in Patients With Previously Untreated Multiple Myeloma

... is indicated for the treatment of patients with mantle cell lymphoma who have received at least one ... of peripheral neuropathy has not been studied in mantle cell lymphoma. Acute development or exacerbation ... liposome injection] study) and previously treated mantle cell lymphoma (N=155) were integrated and ...

Prolonged Progression-Free Survival Demonstrated by VELCADE(R) (Bortezomib) for Injection Based Induction Regimens in Transplant-Eligible Previously Untreated Multiple Myeloma Patients

... of peripheral neuropathy has not been studied in mantle cell lymphoma. Acute development or exacerbation ... liposome injection] study) and previously treated mantle cell lymphoma (N=155) were integrated ... was similar in patients with multiple myeloma and mantle cell lymphoma. In the integrated ...

Novel VELCADE(R) (Bortezomib) for Injection Based Four-Drug Combination Was Well Tolerated In Previously Untreated Multiple Myeloma Patients

... of peripheral neuropathy has not been studied in mantle cell lymphoma. Acute development or exacerbation ... liposome injection] study) and previously treated mantle cell lymphoma (N=155) were integrated ... was similar in patients with multiple myeloma and mantle cell lymphoma. In the integrated ...

New England Journal of Medicine Publishes Phase III Results of VELCADE(R) (Bortezomib) for Injection in Previously Untreated Multiple Myeloma Patients

... is indicated for the treatment of patients with mantle cell lymphoma who have received at least one ... peripheral neuropathy has not been studied in mantle cell lymphoma. Acute development or exacerbation ... liposome injection] study) and previously treated mantle cell lymphoma (N=155) were integrated and ...

Journal of Clinical Oncology Publishes Study of Cephalon Medication TREANDA Plus Rituximab in Relapsed Non-Hodgkin's Lymphoma

... of patients with relapsed indolent B-cell and mantle cell non-Hodgkin's lymphoma (NHL) responded to ... employed in patients with indolent B-cell and mantle cell lymphomas, but resistance to treatment ... 66 patients with relapsed, indolent B-cell or mantle cell lymphoma without documented resistance to ...

VELCADE(R) (Bortezomib) for Injection Based Treatment Delivers Impressive Complete Response and Survival in Patients With Newly Diagnosed Multiple Myeloma

... market leader in relapsed multiple myeloma and mantle cell lymphoma (MCL). "These data, as well as ... indicated for the treatment of patients with mantle cell lymphoma who have received at least one ... was similar in patients with multiple myeloma and mantle cell lymphoma. In the integrated analysis, ...

New Data Show TORISEL Improves Progression-Free Survival for Patients With Relapsed/Refractory Mantle Cell Lymphoma

... show patients with relapsed and/or refractory mantle cell lymphoma (MCL), a form of ... (ASCO) in Chicago. "Relapsed/refractory mantle cell lymphoma is extremely difficult to treat, ... 2 studies of temsirolimus in relapsed/refractory mantle cell lymphoma and indicate that mTOR inhibition ...

New Data Support High Complete Remission Rates With VELCADE(R) (Bortezomib) for Injection Based Therapies in Patients With Newly Diagnosed Multiple Myeloma

... only drug approved for the treatment of relapsed mantle cell lymphoma. "VELCADE based therapies ... therapy for patients with previously treated mantle cell lymphoma (MCL), the most aggressive form of ... About Non-Hodgkin's Lymphoma (NHL) and mantle Cell Lymphoma (MCL) NHL is the most common ...

Sunesis Pharmaceuticals Reports Data from Nonclinical Studies of SNS-032 at the Annual Meeting of the American Association for Cancer Research

... Demonstrates Activity in Multiple Myeloma and mantle Cell Lymphoma SOUTH SAN FRANCISCO, Calif., ... of SNS-032 in multiple myeloma and mantle cell lymphoma. Data from studies conducted in ... between SNS-032's mechanism and its activity in mantle cell ....

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Mantle in Medical Products

UC-Plus Solution

Description:... and achieves a wide area of contact between the femoral and tibial components. Large, uninterrupted pockets of cement create a homogeneous cement mantle to ensure good long-term ....
Company:Plus Orthopedics

Primaloc™ Cemented

Features:... Provides consistent and reproducible cement mantle in the proximal area Macro M/L Steps: ... into compression forces between stem and cement mantle Greater rotational stability in the calcar region Increases cement mantle in the proximal A/P region where loads are ...
Company:Ortho Development Corporation

SHP Acetabular Cup

Features:... in diameters 46 mm to 60 mm to meet all patient needs. ArCom polyethylene - 47% increase in wear resistance. PMMA spacers for uniform 3 mm cement mantle and avoid polyethylene/bone contact. Integral flange with scalloped peripheral rim maintains cement pressurization while allowing excess cement to ...
Company:Biomet Orthopedics, Inc

PE-Plus

Features:... It is a high quality, cost effective option. Made from all polyethylene. The Pe-Plus is fixated using cement. The cement mantle can be individualized for each patient for greater clinical flexibility. Circular grooves allow for optimized cement distribution to pressurize and ...
Company:Plus Orthopedics

MS-30 Hip

Features:... A tri-tapered design and rounded trapezoidal cross-section provide implant stability and an optimal cement mantle interface, standard and offset stems are available for the best anatomical fit; proximal and distal centralizer options are available for the ideal ...
Company:Zimmer, Inc.

Perfecta IMC Stems

Features:... A variety of design features facilitate an even cement mantle thickness, while the intramedullary collars (IMC) promote compressive loading of cement minimizing subsidence and medial migration. Two neck offset ...
Company:Wright Medical Technology, Inc.

The APR Hip Family - CoCr Cemented

Features:... torsional stability. The 2.5 mm proximal polymethylmethacrylate (PMMA) spacers and distal centralizers help to ensure a continuous, uniform cement mantle and help ensure correct positioning. The stem is slightly undersized from the broach (~2 mm) to ensure the continuous cement mantle. The proximal ...
Company:Zimmer, Inc.

Perfecta IMC Slim Neck

Features:... neck geometry increases range of motion and minimizes impingement, polished surface texture to minimize debris generation, cobalt chrome for cement mantle protection and longevity, medial collar for calcar load support, intramedullary collars provide compressive load transfer in the proximal femur, ...
Company:Wright Medical Technology, Inc.

Perfecta PDA Stems

Features:... The Perfecta PDA cobalt chrome promotes long-term mechanical integrity and cement mantle ....
Company:Wright Medical Technology, Inc.
Mantle in Medical Dictionary

Burkitt lymphoma

... . Pictures & Images Lymphatic System ... Lymph oblastic lymphoma , diffuse small noncleaved cell lymphoma / Burkitt lymphoma , and mantle cell lymphoma are 3 types of aggressive adult non-Hodgkin's lymphoma . stimulator) with the potential to treat a broad range of B- cell ...

Cell

... mantle cell lymphoma is found in lymph node s, the spleen , bone marrow , blood , and sometimes the gastrointestinal system ( lymphoma tous polyp ...

Mycosis

... lymphoma , Burkitt's lymphoma , diffuse cell lymphoma , follicular lymphoma , immunoblastic large cell lymphoma , lymph oblastic lymphoma , mantle cell lymphoma , mycosis fungoides, ... Juvenile rheumatoid arthritis Legionnaire's disease Osteomyelitis Pelvic inflammatory disease ...

Spleen

... and are more easily affected; the cells in the blood -forming tissue s ( bone marrow , spleen , and lymph node s) are extremely sensitive. mantle cell lymphoma is found in lymph node s, the spleen , bone marrow , blood , and sometimes the gastrointestinal system ( lymphoma tous polyp ...
Mantle in Biological News

AGU journal highlights -- Aug. 6, 2009

... and brightening Can seismic variation in the mantle be explained by temperature alone? New model ... 8. Can seismic variation in the mantle be explained by temperature alone? The structure and dynamics of Earth's mantle are of great importance because they determine ...

Extraterrestrial platinum was 'stirred' into the Earth

... all the available platinum with it, leaving the mantle and crust with none," Dr Barnes said. ... for the people who study the dynamics of mantle processes and the mechanisms that cause plate ... Osmium isotopes are widely used as tracers of mantle processes, but there has been a mismatch between ...

Mollusks taste memories to build shells

... "The shell is laid down in layers, so the mantle is sensing the history of the mollusk's ... of neurons connecting the sensing cells in the mantle with the secretory cells that produce calcium ... mates. "The pigment is a cue to get the mantle in register so it builds the right shaped shell, ...

February 2009 Geology and GSA Today media highlights

... related to flood basalts suggest the existence of mantle plumes with large heads and thin trailing tails ... plumes). Seismic data suggest the existence of mantle plumes with thick tails (diapir plumes). The ... are different, and in a chemically homogeneous mantle both types are not predicted to coexist. Lenardic ...

The continents as a heat blanket

... The enormous heat in the Earth's core and Earth's mantle generates the flow of rocks within the Earth's ... between the convective movement in the Earths mantle and the continental drift. V. Trubitsin, M. Kaban ... of the continents, the structures of the Earth's mantle obtained through geophysical measurements, and ...

Ancient magma 'superpiles' may have shaped the continents

... the other, Panero said. Plates sink into the mantle as part of the normal processes that shape the ... Panero said. "We know that the rest of the mantle is always moving. So why are the piles still ... Hot rock constantly migrates from the base of the mantle up to the crust, she explained. Hot portions of ...

September Geology and GSA Today media highlights

... of large delta systems elsewhere. mantle upwelling, magmatic differentiation, and the ... regional-scale variations in magma supply or mantle temperature. Toomey and Hooft, however, show that ... crust. Seismic images of crustal and upper mantle structure are combined with gravity data and lava ...

August 2008 Geology and GSA Today media highlights

... now at considerable subsurface depths. mantle earthquakes frozen in mylonitized ultramafic ... from Balmuccia peridotite, a "fossil" of mantle earthquakes. They report a case in which a ... as deep as the boundary between Earth's core and mantle (located 2900 kilometers deep). Tectonic ...

Journey to the center of the earth: Discovery sheds light on mantle formation

... in a paper titled Ancient, highly heterogeneous mantle beneath Gakkel Ridge, Arctic Ocean, appearing ... surface. Mid-ocean ridges like Gakkel, where mantle rock is slowly pushing upward to form new ... locations the least volcanic activity and most mantle exposure ever discovered on a mid-ocean ridge, ...

December GEOLOGY and GSA TODAY media highlights

... cycles and survival of early hominins; an ancient mantle plume and the break-up of Rodinia; relationship ... spatial and temporal overlap of internal mantle flow (endogenic, or internal process) and a large ... in South China: First evidence for >1500 C mantle melts by a ...

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Mantle in Biological Technology

Millennium Over-Delivers on 2007 Goals and Financial Guidance

... treatment for relapsed multiple myeloma and mantle cell lymphoma. Sales increased steadily ... indicated for the treatment of patients with mantle cell lymphoma who have received at least one ... was similar in patients with multiple myeloma and mantle cell lymphoma. In the integrated analysis, ...

Millennium Reports Outstanding Third-Quarter Results Driven by VELCADE(R) (Bortezomib) for Injection Sales

... VELCADE based combinations and re-treatment. In mantle cell lymphoma, our launch continues successfully ... is indicated for the treatment of patients with mantle cell lymphoma who have received at least one ... was similar in patients with multiple myeloma and mantle cell lymphoma. In the integrated analysis, ...

Millennium Announces VELCADE(R) (Bortezomib) for Injection First-Quarter 2008 U.S. Net Sales

... therapy. VELCADE is also indicated for the treatment of patients with mantle cell lymphoma who have received at least one prior therapy. VELCADE is ... profile of VELCADE was similar in patients with multiple myeloma and mantle cell lymphoma. In the integrated analysis, the most commonly reported ...

Millennium Announces 2008 Goals for Growth, Building on Record 2007 Results

... one prior therapy. VELCADE is indicated for the treatment of patients with mantle cell lymphoma who have received at least one prior therapy. VELCADE is ... profile of VELCADE was similar in patients with multiple myeloma and mantle cell lymphoma. In the integrated analysis, the most commonly reported ...

Millennium to Receive $40 Million Milestone Payment for Achievement of Sales Threshold for Velcade(R) (Bortezomib) for Injection

... one prior therapy. VELCADE is indicated for the treatment of patients with mantle cell lymphoma who have received at least one prior therapy. VELCADE is ... profile of VELCADE was similar in patients with multiple myeloma and mantle cell lymphoma. In the integrated analysis, the most commonly reported ...

Proteolix Presents Clinical Data from Two Clinical Studies of Carfilzomib in Multiple Myeloma at the 14th Congress of the European Hematology Association

... has demonstrated single-agent activity in hematologic malignancies and solid tumors, including multiple myeloma, Waldenstrom's macroglobulinemia, mantle cell lymphoma and renal cell carcinoma. Proteolix is conducting a comprehensive clinical development program evaluating carfilzomib for the ...

Proteolix to Present Carfilzomib Clinical Data During the 2009 ASCO Annual Meeting

... has demonstrated single-agent activity in hematologic malignancies and solid tumors, including multiple myeloma, Waldenstrom's macroglobulinemia, mantle cell lymphoma, and renal cell carcinoma. Proteolix is conducting a comprehensive clinical development program evaluating carfilzomib for the ...

Gemin X Pharmaceuticals Selects and Deploys Clinical Force CTMS

... programs. Potential treatment indications for the full scope of pipeline programs span a broad range of hematological and solid tumors, including mantle cell lymphoma (MCL), melanoma, glioblastoma, small cell lung cancer (SCLC), refractory acute lymphoblastic leukemia (ALL) and mastocytosis. For ...

2009 is Healthy for Asia

... Medtech players in China & India such as Meditronics, Alpha X-ray & Shinva. 2009 represents an opportunity for Asia to takeover the mantle of leadership from the US & Europe to become the key driver of innovation and profitability for Healthcare companies. About Frost & ...

Micromet, Inc. Reports Fourth Quarter and Full Year 2007 Financial Results

... marrow and other infiltrated organs from tumor cells. Particularly encouraging was the observation of complete responses in patients with mantle cell lymphoma (MCL) -- a disease that is difficult to treat. In Europe, Micromet has initiated a phase 2 study in acute lymphoblastic ...
Mantle in Biological Dictionary

Mantle

... The mantle is a part of an astronomical object. The ... planets, is chemically divided into layers. The mantle is a highly viscous layer between the crust and the ... mantle (climbing), a rock climbing move used to ...

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