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Malignant in Medical News

Study provides documentation that tumor 'stem-like cells' exist in benign tumors

... been implicated in the genesis of a variety of malignant cancers. Research scientists at Cedars-Sinai ... seen as a possible strategy in the fight against malignant and benign tumors. Cells generated from the ... earlier findings in cancer stem-like cells of malignant brain tumors, the tumor stem cells but not the ...

New piece found in colorectal cancer puzzle

... the expression of inhibitors of the enzyme with malignant cellular behavior. Lotte Vogel, from the ... PN-1, coincides with the acquisition of malignant properties in colorectal tissue". The ... activity via up regulation of PN-1 is causing the malignant progression or if it is a consequence of it". ...

Delivering Chemo Directly Into Brain Tumors Shows Promise

... Survival times for those with malignant gliomas increased, study found ... in early clinical trials, researchers report. malignant gliomas are difficult to treat using standard ... Only about 3 percent of patients diagnosed with a malignant glioma survive five years or more, according to ...

Can EUS elastography help distinguish benign from malignant tissue?

... The differential diagnosis between benign and malignant lymph nodes and focal pancreatic masses based on ... and measure tissue elasticity. Knowing that malignant tissues are generally harder than normal ... information to help distinguish benign from malignant tissue based on their specific tissue ....

New strategy developed to diagnose melanoma

... a technique to distinguish benign moles from malignant melanomas by measuring differences in levels of ... genes that were present at different levels in malignant melanomas compared to benign moles. They narrowed ... strikingly different between the benign and the malignant tissue, providing an additional trait valuable ...

Also in the March 24 JNCI

... infected normal diploid fibroblasts and malignant glioma cells with HCMV or introduced a copy of ... induced telomerase expression in both normal and malignant human cells. Introduction of the viral IE-72 gene ... is of possible relevance for both (initiation of) malignant transformation and oncomodulation by HCMV ...

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Malignant in Medical Technology

CHMP Recommends Approval in the European Union (EU) for New Options for Patients With Certain Primary Brain Tumors

... as monotherapy, and for patients with malignant gliomas, such as GBM or anaplastic astrocytoma ... effective treatment for patients in Europe with malignant gliomas, but is only available orally. Upon ... (EU) in 1999 for the treatment of patients with malignant glioma, such as GBM or AA, showing recurrence or ...

Late-Breaking Data Highlighting Research Advances in Several Blood Disorders to Be Presented At the American Society of Hematology Annual Meeting

... MP L defects cause the overproduction of mature malignant blood cells, but multiple lines of evidence ... of patients (85 percent) had an overproduction of malignant cells mainly dependent on the late stages of ... percent) had an early expansion of very immature malignant progenitor cells, close to the stem cell. ...

FDA Files Application To Convert ONTAK(R) (Denileukin Diftitox) to Full Approval for Use in Cutaneous T-Cell Lymphoma (CTCL)

... patients with persistent or recurrent CTCL whose malignant cells express the CD25 component of the ... patients with persistent or recurrent CTCL whose malignant cells express the CD25 component of the ... and efficacy of ONTAK in patients with CTCL whose malignant cells do not express the CD25 component of the ...

Micromet's BiTE Antibody Blinatumomab (MT103/MEDI-538) Demonstrates Durable Responses in Patients with Relapsed Non-Hodgkin's Lymphoma

... 1 Data Presented at International Conference on malignant Lymphomas Shows Dose Dependent Single ... at the 10th International Conference on malignant Lymphomas (ICML) in Lugano, Switzerland. The new ... advancements and insights in the treatment of malignant lymphomas," said Dr. Michael J. Keating, ...

Anti-TGF-Beta Antisense AP 12009 Shows Very Good Safety and Tolerability in Systemic Treatment of Pancreatic Carcinoma, Malignant Melanoma and Colorectal Carcinoma

... with advanced stage pancreatic carcinoma, malignant melanoma or colorectal carcinoma were included. ... One patient, diagnosed with stage IV malignant melanoma, survived more than 60 weeks after the ... of AP 12009 is safe in patients suffering from malignant tumors, such as pancreatic carcinoma or melanoma. ...

Alfacell Corporation Announces Preliminary Results From ONCONASE(R) Phase IIIb Clinical Trial

... the primary endpoint of survival in unresectable malignant mesothelioma (UMM). However, a statistically ... and orphan-drug designation for the treatment of malignant mesothelioma by the FDA. Additionally, ONCONASE ... multiple molecular mechanisms of action. About malignant Mesothelioma ...

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Malignant in Medical Products

Zilver 518 Biliary Stent

Description:... The Zilver 518 Biliary Stent, a flexible, self-expanding nitinol design intended to treat patients with malignant neoplasms in the biliary system, is now available from Cook Incorporated following clearance by the U.S. Food and Drug Administration. Incorporating ...
Company:Cook Incorporated
Malignant in Medical Definition

Ocular oncology

... orbit can be benign like dermoid cysts , or malignant like rhabdomyosarcoma and retinoblastoma . ... squamous carcinoma , sebaceous carcinoma and malignant melanoma . The most common malignant primary intraocular tumor in adults is ...

Anterior mediastinal mass

... mediastinal compartment, also known as anterosuperior compartment, is anterior to the pericardium. Masses in this area is more likely to be malignant than those in other compartments (1) Most common masses found here include thymomas, germ cell tumors, lymphomas, thyroid tissue, and parathyroid ...

Clean margin

... A clean margin is a medical term referring to the attempt in surgical oncology to resect a tumor with no portion of the malignant growth on microscopic examination by a pathologist extending past a set delineation known as the 'tumor margin'. [1] This is an important ...

Hematopathology

... diseases that are mainly based in lymph nodes . Hematopathologists have named different lymphomas after the type of lymphocyte that has become malignant . Thus there are B cell lymphomas , T cell lymphomas , and NK cell lymphomas . The hematopathologist uses immunohistochemistry and flow ...

Pathology

... , neoplasia , and oncology ( C00-D48 ) Benign tumors Hyperplastic tumor - Cyst - Pseudocyst - Hamartoma - Benign neoplasm malignant progression Dysplasia - Carcinoma in situ - Invasive cancer - Metastasis Topography Anus - Bladder - Bile duct - Bone - ...
Malignant in Medical Dictionary

Asbestos

... smoke! ... A rare type of cancer in which malignant cells are found in the sac lining the chest or ... particles increases one's risk of developing malignant mesothelioma . malignant mixed Mllerian tumor ... other people's ...

Ascites

... severe liver disease and the presence of malignant cells within the abdomen . Search All of ... in blood to assess liver injury . malignant ascites A condition in which fluid containing cancer cells collects in the abdomen . malignant fibrous cytoma ... IA: one ovary , no ...

Basal cell carcinoma

... Figure 1.6. Basal cell carcinoma , low-grade malignant tumor of skin on side of nose. It is a ... cell carcinoma , squamous cell carcinoma and malignant melanoma . There are 3 types of skin cancer : ... cancer s are either basal cell carcinoma s, or malignant melanoma s, two types of skin cancer . ...

Benign

... for changing into cancer ous growths, including malignant melanoma , a form of skin cancer . Alpha ... This growth of the prostate gland is not malignant (not cancer ous), hence its name. Benign ... ... Benign tumor s are NOT cancer ; malignant tumor s are cancer . Cancer is NOT ...

Breast Cancer

... What Is Breast Cancer ? Breast cancer is a malignant tumor that has developed from cells of the breast . A malignant tumor is a group of cancer cells that may ... pain free. Lumps which do not move around may be malignant or may not be. In another type: There is itching ...

Cancer

... s, that are malignant. Like benign tumor s, malignant tumor s do not respond to body mechanisms that ... BONE CANCER - A general term to imply malignant tumor growth in bone. [ Med Help International ... every year! ... Breast cancer is a malignant tumor that has developed from cells of the ...

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Malignant in Biological News

TGen researchers discover possible way to block the spread of deadly brain tumors

... be a serious target for drugs that could prevent malignant tumors from rapidly multiplying and invading ... and rapid division are key characteristics of malignant brain tumors known as glioblastoma multiforme, or ... as having a verified role in contributing to the malignant behavior of the disease," Dr. Berens said. ...

Twin nanoparticle shown effective at targeting, killing breast cancer cells

... targets the Her-2-positive tumor cell, a type of malignant cell that affects up to 30 percent of breast ... antigen, a protein located on the surface on the malignant cell. Put another way, the nanoparticle vehicle ... unloads its "passenger," the cisplatin, into the malignant cell. "It's like a magic bullet," said ...

As rates rise, researchers find better way to identify melanoma

... found a new protein produced excessively in malignant melanoma, a discovery that is particularly ... that IMP-3 is an important progression marker in malignant melanoma," said first author Jennifer G. Pryor, ... mistaken for melanoma but is not cancerous; and malignant melanoma, which has several phases of growth. ...

FSU researcher using computers to hone cancer-fighting strategies

... can best be modified in order to attack and kill malignant tumors while doing minimal harm to a patient's ... *The rate at which immunotoxins bind with malignant cells and the relative amount of antigens ... is possible: If not enough immunotoxins bind with malignant cells, too few cells will be killed with each ...

Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain

... disease, epilepsy, stroke/ischemia, dementia and malignant gliomas RICHMOND, Va. (May 9, 2008) Virginia ... disease, epilepsy, stroke, dementia and malignant gliomas. Neurodegenerative diseases are ... more clearly understand brain cancer, including malignant glioma, an invariably fatal tumor, and how it ...

PET/CT imaging proves golden for detecting cancer in children

... conventional imaging when it comes to detecting malignant tumors in children, according to research ... in children with a wide range of malignant cancers, explained the Hopkins professor of ... for patients with Ewing tumor. Ewings tumor is a malignant bone tumor occurring in children and young ....

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Malignant in Biological Technology

Swedish in Seattle Unveils State-of-the-Art Brain Tumor Center Combining Advanced Treatment With Innovation in Research

... doors to patients diagnosed with both benign and malignant brain tumors. In a move that further establishes ... in the treatment of both benign and malignant brain tumors," said Marc Mayberg, M.D., ... and innovative treatments for both benign and malignant brain tumors. CABTT's unique design places its ...

Paper in Cell Cycle Reports Alfacell's ONCONASE(R) Targets siRNA

... significant efficacy in patients with malignant mesothelioma that failed prior chemotherapy." ... and orphan-drug designation for the treatment of malignant mesothelioma by the FDA. Additionally, ONCONASE ... III clinical trials of ONCONASE in unresectable malignant mesothelioma and, in addition to ongoing efforts ...

Swedish Neuroscience Institute and Institute for Systems Biology in Seattle Form Alliance to Learn More about Brain Diseases

... serious diseases affecting the brain, such as malignant brain tumors," said Dr. Foltz. "Also of ... research into slowing or stopping the growth of malignant brain tumors. "One thing that's made learning ... disease and tremors; brain tumors (including both malignant tumors and benign tumors such as meningiomas); ...

Cellectar, Inc. Begins GMP Production

... the ability to carry the potent isotope inside malignant cells and destroy them without adversely ... radioisotopes that can either image or destroy malignant cells. Cellectar's products' unique mechanism of ... on their accumulation and selective retention in malignant tumors and not in normal cells. The company's ...

FDA Approves EOVIST(R) to Detect and Characterize Focal Liver Lesions

... the kidney. Detection and characterization of malignant and benign focal liver lesions with EOVIST may ... our ability to evaluate patients with benign and malignant focal hepatic lesions will be improved." The ... lesion characterization (i.e., distinction of malignant and benign types of liver lesions). EOVIST ...

Cellectar, Inc. Raises $13 Million in Private Offering

... radioisotopes that can either image or destroy malignant cells. Cellectar's products' unique mechanism of ... on their selective accumulation and retention in malignant tumors and not normal cells. The company's ... that this compound is selectively retained in malignant cells. In pre-clinical studies, CLR1404 was taken ...

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Malignant in Biological Products

Mouse Anti-Human SM22 alpha Monoclonal Antibody, Unconjugated Conjugated, Clone 10H12 from Vision BioSystems

Description:... and visceral forms. It is also reported to be expressed in some rare malignant tumors such as malignant fibrous ....
Company:Vision BioSystems

Cell Transformation Colorimetric Assay Kit from CHEMICON

Description:... Cell Transformation Detection Assay is an anchorage-independent growth assay in soft agar, which is considered the most stringent assay for detecting malignant transformation of cells. For this assay, cells (pre-treated with carcinogens or carcinogen inhibitors) are cultured with appropriate controls in ...
Company:CHEMICON
Malignant in Biological Definition

Cancer

... cells can lead to either a benign tumor or a malignant tumor (cancer). Benign tumors do not spread to ... tissues, and they are rarely a threat to life. malignant tumors can invade other organs, spread to distant ... of the sample are examined closely to see if all malignant tissue has truly been excised. The nature of ...

Tumor

... article about cancer for the main article about malignant tumors. Tumor ( American English ) or ... growth of tissue . This growth can be either malignant or benign . malignant tumors are called cancer . Cancer has the ...

Apoptosis

... fragments of inappropriately expressed proteins (resulting, say, from a malignant mutation) or with foreign antigen produced as a consequence of a viral ... T cells, which are then primed for the eradication of cells undergoing malignant transformation. This apoptosis-dependent pathway for T cell activation is ...

Diabetes mellitus

... pancreatic beta cells, thus producing "artificial" type 1 diabetes. Other pancreatic problems including trauma, pancreatitis or tumors (either malignant or benign) can also lead to loss of insulin production. Currently , type 1 is treated with insulin injections, lifestyle adjustments, and careful ...
Malignant in Biological Dictionary

Plasma cells

... ... In most cases of multiple myeloma, the malignant plasma cells all make an identical Ig. ... ... to a foreign ... Single tumor comprised of malignant plasma cells that occurs in bone or soft ... the complex skill of ... As the name implies, malignant plasma cells collect in multiple foci in the ...

Intestine

... , Leiomyosarcoma , Liposarcoma , Lymphoma , malignant , In anatomy, the intestine is that tubular ... intestine cancer is a rare disease in which malignant (cancer) cells form ... Around 100 ... intestine cancer is a rare disease in which malignant ... The small intestine is part of the body's ...

Skin cell

... layers of cell with melanin in them, and the ... Skin cancer is a malignant growth on the skin which can have many causes. The most common skin ... compelling but just how do ... Skin cancer is a disease in which malignant (cancer) cells form in the tissues of the skin . ... skin condition ...

Pancreas

... and somatostatin, as well as an ... Pancreatic cancer is a malignant neoplasm of the pancreas . Each year in the United States, about 42,470 ... statistics, as well as chemotherapy, radiation, and surgical treatments of malignant tumors of the pancreas . Pancreas divisum is a common congenital ...

Cervical

... response. 9 Additional ... Cervical mucus ... Cervical cancer is malignant cancer of the cervix uteri or cervical area. It may present with ... of cervical cancer. ... Cervical cancer is a disease in which malignant (cancer) cells form in the ... Working to enhance awareness of ...

Cancer

... uncontrolled growth, invasion, and sometimes metastasis . These three malignant properties of cancers differentiate them from benign tumors, which ... ... statistics, facts, and survival rates, and get information about how malignant tumors (cancerous growths) metastasize or spread. Information on many ...

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