Eleven Veterinary Students Win Top Awards at Morris Animal Foundation's Annual Research Competition

... Award for Companion Animals, $5,000 each ( tie ) Mia Lieberman, University of California-Davis D07EQ-622 : "Isolation and Purification of lytic Bacteriophages Against Streptococcus equi subspecies equi " Stephanie Montgomery, North Carolina State University D07CA-627 : ...

Pharmacomechanical Thrombectomy Procedure Adoption to Accelerate Due to More Aggressive Treatment of Deep Vein Thrombosis, According to Millennium Research Group

... as demonstrate how PMT may have lower bleeding risks compared with traditional CDT alone," says Darren Navarro, Senior Analyst at MRG. "The reduced lytic doses and shorter treatment times in the intensive care unit afforded by PMT make this procedure safer and more user-friendly for the physician, and ...

Treatment Target for Herpes Pinpointed

... is likely to be left behind, which promotes the establishment of latency," Sawtell said. In essence, the herpes virus uses VP16 to balance the lytic and dormant stages of its life cycle. In a second study, this one appearing recently in the online issue of Nature Immunology , a team of ...

Rockefeller University's Center for Clinical and Translational Science funds 18 new pilot studies

... Laboratory of Bacterial Pathogenesis and Immunology, to develop a temperature-stable and topically active formulation of ClyS, a newly developed lytic enzyme that is effective against multidrug-resistant strains and all other species of Staphylococcus aureus. This trial also aims to develop a skin ...

DNA damage response confers a barrier for viral tumorigenesis

... The study will be published 28.9.2007 in Public Library of Science (PLoS) Pathogens. KSHV displays two patterns of infection: latent and lytic phase. During latency, only a restricted set of viral genes is expressed. The KSHV genome encodes several homologues of cellular proteins, which ...

Philadelphia Researchers Found A Novel Way To Fight Several Kind of Cancers

... experiments, this experimental therapy, called lytic induction therapy, results in tumor death. ... one of the genes that is expressed upon viral lytic induction is EBV's thymidine kinase (EBV-TK), an ... a proteasome inhibitor, but it also induces the lytic cycle thereby activating the TK in the ...

A Novel Treatment for KSHV-infected Lymphomas

... patients. There are no current therapies effective against the aggressive KSHV-induced PEL. KSHV displays two patterns of infection: latent and lytic phase. During latency, only a restricted set of viral genes is expressed. The KSHV genome encodes several homologues of cellular proteins, which ...

Bisphosphonates to Treat Multiple Myeloma

... of life while the cure is sought. Because bone destruction causes significant problems for MM patients, and painful results include osteoporosis, lytic bone disease and skeletal fractures, clinicians seek to treat this condition aggressively. Bisphosphonates are synthetic equivalents of ...

Lytic in Medical Technology

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

... in cancer. EP-100 is the first candidate from the Company's Cationic lytic Peptide (CLYP(TM)) platform technology. EP-100 is a targeted ... is developing a new class of targeted anticancer drugs using its Cationic lytic Peptide (CLYP(TM)) platform technology. These drug candidates, called ...

Lytix Presents LTX-109 Anti-Microbial Data at ICAAC

... Presented at ICAAC in Washington, DC, the studies showed that the novel lytic peptidomimetic has an ultra-rapid bacteriocidal effect, significantly ... established in 2003 to commercialise world-class research in the field of lytic peptides spun out by the founding scientists working in the University ...

Metastatic Bone Disease Patients Can Walk in Lazarus' Footsteps

... said Anselmetti. He noted that osteoplasty provided effective pain regression for individuals with both painful bone metastases and benign lytic lesions that didn't respond to conventional analgesic treatment. Bones are the third most common location where cancer cells spread and ...

Jennerex Presents Clinical Data From JX-594 Demonstrating Tumor Efficacy Against Advanced Liver Cancers

... 23 /PRNewswire/ -- Jennerex Biotherapeutics today presented clinical data from a Phase 1 / 2 trial of JX-594 -- the company's proprietary targeted lytic and immunostimulatory armed virus therapy -- demonstrating objective evidence of efficacy in 10 of the 13 evaluable patients with advanced ...

Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop

... 100 percent disappearance of M-protein (a marker of tumor burden); negative immunofixation testing; no increase in size or number of lytic bone lesions; and disappearance of soft tissue tumors (plasmacytomas). "Partial" remissions and "minimal" responses represented lesser degrees of ...

Lytic in Medical Products

Streck-Lysing Agent IIIA Lytic Reagent

Description:... A lytic reagent manufactured for the simultaneous quantitative determination of hemoglobin and white blood cells. Streck-Lysing Agent IIIA is manufactured ...
Company:Streck

Streck-Lysing Agent IIIC Lytic Reagent

Description:... A lytic reagent manufactured for the simultaneous quantitative determinations of hemoglobin and white blood cells. Streck-Lysing Agent IIIC is for use on ...
Company:Streck

Streck-Lysing Agent III Lytic Reagent

Description:... A lytic reagent manufactured for the simultaneous quantitative determinations of hemoglobin and white blood cells. Streck-Lysing Agent III is for use on the ...
Company:Streck

Streck-Hemoglobin/Lyse Lytic Reagent

Description:... Streck-Hemoglobin/Lyse is a lytic reagent for the quantitative determination of hemoglobin on the Abbott CELL-DYN® 3000. The shelf life is two years from the date of ....
Company:Streck

Streck-CD3500 Hemoglobin/Lyse Lytic Reagent

Description:... Streck-CD3500 Hemoglobin/Lyse is a lytic reagent for the quantitative determination of hemoglobin on the Abbott CELL-DYN® 3500 and 3700. The shelf life is two years from the date of ...
Company:Streck

Streck-CN free Lyse CD Lytic Reagent

Description:... An environmentally-safe, CN-free lytic reagent designed for use on the Abbott CELL-DYN® 1800 three-part differential hematology ....
Company:Streck

Xpeedior +120 Catheter

Description:... is fragmented by the jets, and removed from the body. AngioJet thrombectomy provides rapid restoration of flow in minutes, as opposed to hours with lytic therapy. The Xpeedior+120 catheter has a new 120cm length for additional reach and flexibility for contralateral procedures. The braided shaft ...
Company:Possis Medical, Inc.

Trellis Infusion Catheter

Features:... Percutaneous Peripheral Devices: 6 French Catheter System Isolation of Therapeutic Area: Localization of lytic Agent, Dose &Time Reduction Inherent Embolic Protection: Double Balloon System, Aspiration Controlled Mixing: Increases Surface Area ...
Company:Bacchus Vascular

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Lytic in Medical Dictionary

Strain

... few years. Type B causes smaller outbreaks, and Type C usually causes mild illness. An extract made from cancer cells that are infected with a lytic strain of virus . The extract contains both cancer cell protein s and virus protein s. Oncolysates are being studied as cancer vaccine ...

Lytic in Biological News

Study reveals how viruses collectively decide the fate of a bacterial cell

... the pathway that kills the host cell called the lytic pathway or the pathway where it remains dormant ... cell called the lysogenic pathway. When the lytic pathway is selected, the virus utilizes bacterial ... change, which can result in a switch to the lytic pathway. The decision of the genetic circuit ...

Metastatic bone disease patients can walk in Lazarus' footsteps

... said Anselmetti. He noted that osteoplasty provided effective pain regression for individuals with both painful bone metastases and benign lytic lesions that didn't respond to conventional analgesic treatment. Bones are the third most common location where cancer cells spread and ...

New paper sheds light on bacterial cell wall recycling

... wall components to observe the chemical reactions that take place during the recycling process. The researchers found that a member of the lytic transglycosylases family of enzymes known as M1tB performed the requisite cell wall fragmentation on the synthetic sample of the cell wall from their ...

Control switches found for immune cells that fight cancer, viral infection

... and then starts secreting the acid and other compounds that break down the bone." NK cells have to form a similar plunger-like bond, known as a lytic synapse, with the targets they attack. They do not make cortactin but produce HS1, which is a very similar protein. Butler decided to see what would ...

Researchers wake up viruses inside tumors to image and then destroy cancers

... experiments, this experimental therapy, called lytic induction therapy, results in tumor death. ... one of the genes that is expressed upon viral lytic induction is EBV's thymidine kinase (EBV-TK), an ... a proteasome inhibitor, but it also induces the lytic cycle thereby activating the TK in the ...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

... and Metastases with a Combination of LHRH and lytic Peptide, Hecate, bound to Iron Oxide ... they found evidence that the alternating LHRH and lytic peptide on the ironoxide particle was effective ... the cell membrane. "It is possible that if the lytic peptide has no interaction with the membrane it ...

Researchers from the UGR use a bacterium to obtain biopreservatives from food

... for nutrients in their environment. One of these strategies is to produce antimicrobial compounds such as antibiotics, certain metabolism products, lytic agents, numerous types of protein exotoxins, and bacteriocins. It has become increasingly more necessary to find new antimicrobial agents because of ...

Finnish scientists discovered a new approach to treat virus-induced lymphomas

... patients. There are no current therapies effective against the aggressive KSHV-induced PEL. KSHV displays two patterns of infection: latent and lytic phase. During latency, only a restricted set of viral genes is expressed. The KSHV genome encodes several homologues of cellular proteins, which ...

Worms produce surprise insight into human fever

... cells, including ours. These conserved pathways are involved in many similar “effector?strategies against hostile bugs peristalsis, low gut pH, lytic enzymes, and antimicrobial peptides to prevent microbial colonization of the intestine. In dissecting two conserved pathways required for C. ...

Newly discovered protein kills anthrax bacteria by exploding their cell walls

... conditions. "PlyPH works in an extremely wide pH range, from as low as four to as high as eight," says Fischetti. "I don't know of any other lytic enzyme that has such a broad range of activity." In addition, PlyPH, like PlyG, is highly specific in terms of the types of bacteria it affects. ...

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Lytic in Biological Technology

Lytix Closes USD 10.4 Million Funding Round

... million NOK (US$ 10.4 million), the proceeds of which will fund the early-stage clinical development of two novel drugs. Lytix develops novel lytic peptide drugs for the treatment of resistant bacterial and fungal infections, as well as first-in-class oncology treatments - both areas with high ...

Major Medical Journal Reports Higher Success, Fewer Complications and Lower Cost Treating DVT With Trellis(R) Isolated Thrombolysis Compared With Catheter-Directed Thrombolysis

... Majority of DVT Cases Treated in Single-Setting With Trellis-8 Catheter From Bacchus Vascular, Reducing Patient lytic Exposure, Bleeding Complications and Treatment Cost SANTA CLARA, Calif., March 6 /PRNewswire/ -- Bacchus Vascular Inc., ...

Genomic Analysis of Formalin-Fixed Paraffin Embedded (FFPE) Tissues through the use of Whole Genome Amplification (WGA)

... for fresh, frozen or fixed tissues, includes reagents to effect a very gentle extraction. The lysis uses a combination of proteinase K and lytic detergent, and draws from the experience gained in the development of the Sigma Extract-N-Amp ™ reagent line. Efficient, gentle lysis and a ...

A Positive Selection Assay for Mutation Analysis in Big Blue Animals

... to lysogenize. When grown under conditions that favor lysogeny, lambda prophages carrying such mutations ( l cII ) survive only by entering the lytic pathway of development, forming plaques. Prophages that are wild type for the cII region ( l cII + ) integrate into the host genome ...

Lytic in Biological Products

Yeast Protein Kit from Zymo Research

Description:... cells. The kit has been optimized for use with S. cerevisiae and C. albicans but can be used for any fungus species that is susceptible to yeast lytic enzyme digestion. The Zymolyase digestion procedure effectively generates spheroplasts of yeast cells that are ideal for both protein and DNA ...
Company:Zymo Research

Lytic in Biological Definition

Lytic cycle

... The lytic cycle is one of the two cycles of viral ... but rather as somewhat interchangeable. The lytic cycle is typically thought of as the main method ... and lysis Description The lytic cycle is a three-stage process. Infection ...

Lambda phage

... active again, excises itself from the DNA of the host cell and enters its lytic cycle . The reactivated phage takes apart the host's DNA and "reprograms" ... state if cI proteins predominate, but will be transformed into the lytic cycle if cro proteins predominate. The cI dimer may bind to any of ...

Virus

... material , but for proteins needed by the virus during lysogenic and lytic cycles , the reproductive cycles. Contents ... late proteins , proteins used to construct the virus coat; and lytic proteins , enzymes used to break open the cell for viral exit. The final ...

Lytic in Biological Dictionary

Lytic cycle

... The lytic cycle is one of the two cycles of viral ... but rather as somewhat interchangeable. The lytic cycle is typically considered the main method of ... can ... MySpace Music profile for The lytic Cycle - Tour Dates Up! ... Free Download - The ...

Lambda phage

... phage by using a ... Recombinant lambda phage are usually less lytic than wild-type. We recommend growing recombinant lambda phage on ... genome into the bacterium, the genome converts from a ... will enter a lytic cycle, produce new phage particles and "jump ship" ... Don't forget ...

Bacteriophage lambda

... structure of bacteriophage ... The decision for lambda to enter the lytic or lysogenic cycle when it first ... BACTERIOPHAGE LAMBDA . LAMBDA ... vector, lambda , PCR, polymerase chain reaction, ... ... the lytic and lysogenic processes o bacteriophage lambda in a bacterial cell ...

Vacuole

... thesaurus, Word of the Day, and word games. Encyclopedia article about Vacuole . Information about Vacuole in the Columbia ... In animals, a lytic vacuole known as the lysosome typically functions to process ... ... information on Vacuole ... They also use contractile vacuole s to ...

Sensory neurons

... neurons . ... Sensory neurons may not regenerate, so an immune system ... CD8 T cells target infected sensory neurons . " Instead, the lytic granules attack ... even at the level of primary sensory neurons : experi ... interactions between the sensory neurons of different ... ...

Prophage

... A prophage is the phage DNA in its dormant state, and is either integrated into ... The prophage expresses gene(s) that repress the phage's lytic action, and the ... Todar's Online Textbook of Bacteriology chapter on bacterial viruses. ... Print this Page ... Information about prophage ...

Bacteriophages

... treat pathogenic bacterial infections. Although extensively used and developed mainly in former Soviet Union countries ... Animations of the lytic life cycle of a bacteriophage . ... Bacteriophages can have a protein "tail" attached to the ... Have questions about bacteriophages ? ... ( ...

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