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Lymphocyte in Medical News

Cell division find prompts overhaul of immune response modeling

... deaths. They also recorded how this variation in lymphocyte behaviour was transmitted through cell ... Professor Hodgkin said it appeared that when a lymphocyte first divided chemicals were produced that were ... accurate information on the time it takes for a lymphocyte to divide, the time taken to die and the number ...

Dr. Wei Sun, PhD, MD Joins SpectraCell Laboratories

... well as research experience within the areas of lymphocyte activation, lymphocyte subset analysis, apoptosis, and T-cell culture. ... in an MD, PhD whose primary experience is with lymphocyte function is a perfect fit for SpectraCell," ...

A new light on tumor immunotherapy for gastric cancer

... are believed to be essential for stimulating tumor-specific cytotoxic T lymphocyte (CTL) and inducing the protective and therapeutic anti-tumor immunity. ... were analysed by morphological observation, phenotype analysis, and mixed lymphocyte reaction (MLR). BM-DCs were pulsed with tumor cell lysate obtained by ...

Antiviral therapy helps children at risk for post-transplant lymphoproliferative disease

... normal immune response to the virus, leading in some cases to uncontrolled lymphocyte B proliferation. Antiviral therapy is one possible way to address the ... disease (PTLD) by blocking the viral replication that can lead to lymphocyte B proliferation. After a median 8 months of treatment, EBV-DNA became ...

Blood Test Shows Statistically Significant Association With Alzheimer's Disease (AD), May Predict Conversion of Mild Cognitive Impairment to AD

... of the characteristic pathologies of the disease, the amyloid plaques and tau tangles. Most importantly, the findings validate the use of our lymphocyte test as a biomarker of Alzheimer's disease and suggest that the test is predictive of cognitive deficit developing in MCI patients." About ...

New Report Just Published: World Multiple Myeloma Therapeutics Market Report

... II-34 Targeted Therapy II-34 Gene Therapy II-34 Immunotherapy II-34 Monoclonal Antibody Treatment II-35 Vaccines II-35 Donor lymphocyte Infusion II-35 Hematological Cancer Drug Classes II-35 Hypomethylating Agents & Antimetabolites II-35 Bisphosphonates II-36 ...

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Lymphocyte in Medical Technology

Lexicon Files Investigational New Drug Application for LX2931 as a Potential Treatment for Rheumatoid Arthritis

... review. "As an orally-delivered modulator of lymphocyte activity, we believe LX2931 has potential to be ... in the sphingolipid pathway, which controls lymphocyte circulation and trafficking to peripheral sites ... including rheumatoid arthritis, reduction of lymphocyte buildup at sites of disease activity holds ...

Tolerx Presents Data at 69th Scientific Sessions of the American Diabetes Association

... is a novel monoclonal antibody being developed for the treatment of type 1 diabetes and other autoimmune diseases. Otelixizumab targets CD3, a T lymphocyte receptor involved in normal cell signaling. Otelixizumab has not yet been approved for marketing. Data suggest that the antibody may work in ...

New Hope to Beat Cancer

... immune system to kill cancer cells. (Logo: http://www.newscom.com/cgi-bin/prnh/20090303/CG78204LOGO-b ) The Young Tumor-Infiltrating lymphocyte (Y-TIL) trial is a phase 2 clinical trial being offered with technical support from the National Cancer Institute (NCI) in Bethesda, Md. Milwaukee ...

GeneThera Announces it is Set to Begin Commercial Testing for Johne's Disease as Soon as January, 2009.

... the microorganism elicits a cell-mediated response by the host that can be characterized by strong delayed-type IV hypersensitivity reactions, lymphocyte proliferative responses to mitogens, and production of cytokines by stimulated T lymphocytes. As the disease progresses from sub clinical to clinical ...

Markers in Blood and Spinal Fluid, and a New Imaging Agent, Show Promise for Early Detection of Alzheimer's

... about dementia and fostering a vital, collegial research community. -- Thomas Arendt. "Diagnosis Of Alzheimer's Disease Using Peripheral Blood lymphocyte Expression Of CD-69 Following A Mitogenic Stimulus." (Funders: National Institutes of Health, GW Medical, Provista Life Sciences) -- Anne M. Fagan. ...

IDM Pharma Announces Phase 2 Follow-Up Data Showing IDM-2101 is Well Tolerated With Positive Survival Trend in Non-Small Cell Lung Cancer Patients

... follow-up results from the Phase 2 study of IDM-2101 showing that the product candidate was well tolerated, induced broadly specific cytotoxic T lymphocyte (CTL) responses, and showed a positive survival trend in HLA-A2 positive patients with non-small cell lung cancer (NSCLC) who were treated with ...
Lymphocyte in Medical Products

Giemsa Stain

Description:... a very light, pale pink. Leukocyte nuclear chromatin stains magenta-purple, monocyte cytoplasm stains the classical "ground glass" blue and lymphocyte cytoplasm stains clear, sky ....
Company:Richard-Allan Scientific

Particle Analysing System PAS

Description:... Multiparameter laser and arc lamp flow cytometer for all applications in immunology, microbiology, cell biology, pathology, hematology, lymphocyte dubset and cell ....
Company:Partec GmbH

Epstein-Barr Virus (EBV) VCA IFA IgG

Features:... The recombinant substrate eliminates the problem of interference from early antigen expression which occurs in substrate slides prepared with a human lymphocyte line. ...
Company:Focus Diagnostics

Epstein-Barr Virus (EBV) VCA IgM Recombinant IFA (RIFA)

Features:... The recombinant substrate eliminates the problem of interference from early antigen expression which occurs in substrate slides prepared with a human lymphocyte line. ...
Company:Focus Diagnostics

Epstein-Barr Nuclear Antigen (EBNA) ACIF (Anti-Complement Immunofluorescence)

Features:... The recombinant substrate eliminates the problem of interference from early antigen expression which occurs in substrate slides prepared with a human lymphocyte line. ...
Company:Focus Diagnostics

Epstein-Barr Virus (EBV) Early Antigen IFA

Features:... The recombinant substrate eliminates the problem of interference from early antigen expression which occurs in substrate slides prepared with a human lymphocyte line. ...
Company:Focus Diagnostics
Lymphocyte in Medical Definition

Hematopathology

... . Hematopathologists have named different lymphomas after the type of lymphocyte that has become malignant . Thus there are B cell lymphomas , T cell ... and flow cytometry , techniques using antibodies to specific lymphocyte surface markers , to determine the type of lymphoma in the pathology ...

Thymocyte

... cytokine and chemokine receptors. J Immunol. 2007 Feb 15;178(4):2008-17. http://www.jimmunol.org/cgi/content/full/178/4/2008 ] ^ Sleckman BP, lymphocyte antigen receptor gene assembly: multiple layers of regulation. Immunol Res 32:153-8, 2005. full text ^ Baldwin TA, Hogquist KA, Jameson SC, ...
Lymphocyte in Medical Dictionary

Acute lymphoblastic

... immature white blood cells destined to become lymphocyte s. Adult Acute Lymphoblastic Leukemia in ... leukemia s. In this form of the disease , the lymphocyte cell line is affected. The lymphocyte s normally fight infection . acute ...

Cell

... marker protein s on the surface of B- lymphocyte s (a type of white blood cell ). Large- ... of the body (metastasized). T- Cell or T- lymphocyte A lymphocyte (white blood cell ) that develops in the ...

Hairy cell leukemia

... in which the bone marrow makes too many lymphocyte s (a type of white blood cell ). Gender and ... which your bone marrow makes too many B cells ( lymphocyte s), a type of white blood cell that fights ... A rare type of leukemia in which abnormal B- lymphocyte s (a type of white blood cell ) are present in ...

HIV

... infection -fighting cells are called T- cell lymphocyte s. HIV is usually diagnose d using a blood ... cells (variously called T4, CD4, or T-helper lymphocyte s) that would ordinarily fight off such a viral ... targets a type of white blood cell called T4 lymphocyte s and injects its genetic material, instructing ...

Immune response

... that induces the production of antibodies and lymphocyte s capable of destroying the antigen or making ... the kidney (glomerulus) ultrastructure. lymphocyte s are responsible for immune response s. There are two main types of lymphocyte s: B cells and T cells. Remune Immune -based ...

Immunofluorescence

... Alternate Names : B and T lymphocyte Assays, Direct Immunofluorescence , E-Rosetting, T and B lymphocyte Assays Definition A test that makes a quantitative measurement of T and B lymphocyte s in the blood . Immunofluorescence Assay. ...

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Lymphocyte in Biological News

Seemingly suicidal stunt is normal rite of passage for immune cells

... that normally helps the cell sense DNA damage. "This explains why the lymphocyte counts in these patients drop so sharply," Sleckman says. "Not only is the ... line developed in his lab, researchers induced double-stranded breaks in lymphocyte DNA using the same enzymes the cells normally use to create the breaks. ...

3 Columbia University Medical Center faculty elected to Institute of Medicine

... and her laboratory work focuses primarily on transcriptional regulation of lymphocyte development. A major focus of her current work is an unusual transcriptional repressor called Blimp-1 (B lymphocyte induced maturation protein). Her studies on Blimp-1 are revealing ...

Researchers explore new driver of transplant rejection: Platelets

... for attacking organ injury and rejection head-on, says Rabb. The traditional target of current anti-rejection medicine is the so-called T lymphocyte a white blood cell believed to be the major orchestrator of the immune response against any foreign tissues, including transplants. "The thought ...

UC Davis researchers discover how HIV turns food-poisoning into lethal infection

... revealed that viral infection of the intestine results in the depletion of a type of white blood cell, called Th-17, in the gut mucosa. This T helper lymphocyte produces IL-17, a cytokine or chemical messenger that plays a crucial role in the inflammatory response, recruiting other immune system cells to the ...

Glue inside the cell

... process of de-ubiquitination is constantly happening in cells and it could contribute to prevent an over-shooting activation of T cells. Unopposed lymphocyte activity is responsible for many chronic diseases, autoimmunity or even lymphoma development. Future work must address the status of Malt1 ...

How T lymphocytes attack

... Recognition of the tumour antigen determines T lymphocyte behaviour To arrive at their conclusion, the ... at all stages of development. However, T lymphocyte behaviour varied in antigen-containing tumour; when the tumour stopped growing because of the lymphocyte injection three or four days previously, the ...

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Lymphocyte in Biological Technology

BioCryst Reports First Quarter 2008 Financial Results and Clinical Update

... showed a dose response effect on reducing lymphocyte counts at doses up to 1040mg administered once ... effects on reduction of peripheral blood lymphocyte counts. Affected lymphocyte subsets in the Phase II study included CD4+, ...

Trubion Announces Acceptance of Three Presentations on Its TRU-016 Product Candidate at the 2009 ASCO Annual Meeting

... and early signs of efficacy of TRU-016 as shown by a reduction in tumor lymphocyte blood counts, reduction in lymph node and spleen size, and/or an ... leukemia cutis, and the other six had 27% to 94% reduction in peripheral lymphocyte count. One patient had an increase in hemoglobin of 40% and a reduction in ...

Sunesis Reports Financial Results for the Second Quarter 2009

... million for the same periods in 2008. Sunesis recognized $2.0 million in the second quarter of 2009 for the sale to SARcode of its interest in the lymphocyte function-associated antigen-1, or LFA-1, patents and related know-how that had previously been the subject of a license agreement with them, and $1.5 ...

Medarex Announces Presentations at Annual Meeting of the American Society of Clinical Oncology

... - Poster discussion from 2:00 p.m. to 6:00 p.m. local time on Sunday, May 31, 2009. "Association of peripheral blood lymphocyte count (ALC) and clinical activity in patients (pts) with advanced melanoma treated with ipilimumab" (Abstract #3020, Developmental Therapeutics: ...

CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies

... in vivo in the mouse. Dendritic cells direct the subsequent immune response to a vaccine by presenting the vaccine's antigen(s) to the appropriate T lymphocyte and then deliver specific cytokine proteins to the T cell to determine the immune response outcome to the specific vaccine. Each L.E.A.P.S. ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... characteristics. Dendritic cells direct the subsequent immune response to a vaccine by presenting the vaccine's antigen(s) to the appropriate T lymphocyte and then deliver specific cytokine proteins to the T cell to determine the immune response outcome to the specific vaccine. "L.E.A.P.S. vaccines are ...

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Lymphocyte in Biological Definition

Antibody

... on its surface. The antibodies a single B lymphocyte produces can differ in their heavy chain and the ... membrane , where it can be recognized by a T lymphocyte , which compares it to similar structures on the cell membrane of a B lymphocyte . If it finds a matching pair, the ...

B cell

... Prize in Physiology or Medicine for demonstrating how B cells create the enormous diversity of antibodies from only a few genes. See also T lymphocyte Antibody ...

Immune system

... /CD8 receptor / perforin / apoptosis /clonal selection immunosuppression immunosuppressive drug immunotherapy lymphatic system / lymphocyte macrophage major histocompatibility complex / class I MHC /class II MHC monoclonal antibody / polyclonal antibody ...

Synapse

... of the enzyme acetylcholinesterase . By analogy to true synapses described above, the interface between an antigen presenting cell and lymphocyte is sometimes called an immunological synapse . References M.F. Bear, B.W. Conners, and M.A. Paradiso. 2001. Neuroscience: Exploring the ...

T cell

... (CD4 + ) are "middlemen" in the immune response. When they get activated, they proliferate and secrete cytokines, that regulate or 'help' effector lymphocyte function. They are known as one of the targets of HIV infection, and the decrease of CD4 + T cells results in AIDS . Some helper T cells secrete ...

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Lymphocyte in Biological Dictionary

T lymphocytes

... immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer ... count measurement . Information about T lymphocyte in the free online English ... T cell. lymph cell, lymphocyte - an agranulocytic leukocyte that normally makes ...

Lymphocytes

... Presenting Cells (APCs) and ... lymphocyte ( ) n. Any of the nearly colorless cells found ... to understand definition for the medical term, lymphocyte . ... What can cause the level of lymphocytes ... system and move into tissues as needed. lymphocyte ... Immune System Series--in-depth look at ...

B lymphocytes

... in apoptosis at ... Information about B lymphocyte in the free online English ... PDB has ... B lymphocytes , usually called ... A B lymphocyte is a type of white blood cell. Also called B ... abilities" ... As a measure of B lymphocyte repertoire diversity, we have analysed size ... ...

T cell

... role in cell -mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a ... dictionary and encyclopedia. cytotoxic t ... T cell - a small lymphocyte developed in the thymus; it ... However, the precursors of T cells ...

Hybridoma

... is produced in the laboratory from the fusion of an antibody-producing lymphocyte and a nonantibody-producing cancer cell, Hybridoma publishes fully ... and ... hybridoma - a hybrid cell resulting from the fusion of a lymphocyte and a tumor ... We handle all hybridoma technology procedures from ...

Uropod

... a uropod -specific marker, CD44. ... Figure 2. MTs reorient toward the uropod after polarization by fMLF in suspended ... Microspikes on the lymphocyte Uropod . William McFarland 1 ... Leukocyte uropod formation and membrane/cytoskeleton linkage in immune interactions. ... The number of ...
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