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Locus in Medical News

Einstein scientists propose new theory of autism

... disorder caused by impaired regulation of the locus coeruleus, a bundle of neurons in the brain stem ... that scientific evidence directly points to the locus coeruleusnoradrenergic (LC-NA) system as being ... professor of neuroscience at Einstein. The locus coeruleus has widespread connections to brain ...

New Genetic Links to Baldness Discovered

... alopecia [hair loss]. We are sure that this new locus we found is the second most important." The ... said. "Screening for the X chromosome locus and also for this new one can possibly show the ... inherited from his mother. The new gene locus is on chromosome 20. Men and women alike have two ...

Also in the Sept. 9 JNCI

... Confirmation of Association with Chromosome 15 locus and Familial Lung Cancer Two ... reported an association between the 15q24-25.1 locus and sporadic lung cancer risk. To confirm ... found a strong association between the 15q24-25.1 locus and familial lung cancer. Two SNP variants were ...

Findings on bladder-brain link may point to better treatments for problems in sleep, attention

... structures, the Barrington's nucleus and the locus ceruleus, developed abnormal activity as a result of the bladder obstruction. In particular, the locus ceruleus showed persistently high activity, and ... but added that the brain circuits involving the locus ceruleus might be a useful target for drugs to ...

Specific location of the TRAF1/C5 gene associated with multiple autoimmune diseases

... Paris, France, Friday 13 June 2008: The TRAF1/C5 locus on chromosome 9 has been revealed to play a role ... a further link was also found between the gene locus and the presence of autoantibodies (antibodies ... of our study have shown that the TRAF/1C5 gene locus may have an important role in multiple autoimmune ...

Presentations at AHA expand on clinical utility of deCODE's DNA-based tests

... Room 265-266, presentation number 4404, "Variation in the 4q25 chromosomal locus predicts new-onset atrial fibrillation after cardiac surgery." Presenter: ... presentation number 5090, "Impact of adding a single allele in the 9p21 locus to traditional risk factors on risk classification for coronary heart ...

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Locus in Medical Technology

Findings on Bladder-Brain Link May Point to Better Treatments for Problems in Sleep, Attention

... structures, the Barrington's nucleus and the locus ceruleus, developed abnormal activity as a result of the bladder obstruction. In particular, the locus ceruleus showed persistently high activity, and ... but added that the brain circuits involving the locus ceruleus might be a useful target for drugs to ...

A Milestone in Cancer Genetics: deCODE Discovers First Common Genetic Variants Affecting the Risk of Many Types of Cancer

... help to tag major biological mechanisms underlying cancer susceptibility more generally. The paper, entitled "Sequence variants at the TERT-CLPTM1L locus associate with many cancer types," is published today in the online edition of Nature Genetics at www.nature.com/ng , and will appear in an upcoming ...

EnVivo Pharmaceuticals Announces Initiation of Clinical Safety and Biomarker Study of Alpha-7 Nicotinic Agonist, EVP-6124, in Patients with Schizophrenia

... to suppress the response to a second stimulus. Sensory gating abnormalities in Schizophrenia have been linked to an allele on chromosome 15, the gene locus for the alpha-7 receptor. Alpha-7 nicotinic agonists have been recently shown to improve cognition and the P50 response in patients with ...

Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers

... a patented microarray-based approach to map tumor associated changes in DNA methylation, alterations that can affect normal gene expression. A single locus associated with the GHSR gene was the most powerful biomarker in the study, with a clinical sensitivity of 90% and a specificity of 96% for ...

Researchers Discover a Common Variation in a Gene Segment that Increases the Risk for Prostate Cancer

... Resource: Yeager M, Orr N, Hayes RB, et al. Genome-wide association study of prostate cancer identifies a second locus at 8q24. Nature Genetics. Online April 1, 2007. -------------------------------------------------------------------------------- CONTACT: NCI ...

The Past, Present and Future of HLA Typing

... the Class II proteins, which associate with and present exogenous antigens to CD4+ T-cells, are expressed by the HLA DR, -DQ and DP loci. Each locus is highly polymorphic; for example, there appear to be 300+ alleles in the HLA-B or DRB1 loci. A clear understanding of the differences between HLA ...
Locus in Medical Products

DPB1 SSP UniTray®

Description:... Direct to High Res SSP kits provide high resolution typing of the entire locus with a single tray. locus specific typing on a single tray reduces QC and testing costs while saving ...
Company:Dynal Biotech, LLC

DQB1 SSP UniTray®

Description:... Direct to High Res SSP kits provide high resolution typing of the entire locus with a single tray. locus specific typing on a single tray reduces QC and testing costs while saving ...
Company:Dynal Biotech, LLC

DQA1 SSP UniTray®

Description:... Direct to High Res SSP kits provide high resolution typing of the entire locus with a single tray. locus specific typing on a single tray reduces QC and testing costs while saving ...
Company:Dynal Biotech, LLC

DRB96 SSP UniTray

Description:... Direct to High Res SSP kits provide high resolution typing of the entire locus with a single tray. locus specific typing on a single tray reduces QC and testing costs while saving ...
Company:Dynal Biotech, LLC

B Locus High Res SSP UniTray®

Description:... I Direct to High Res SSP kits provide high resolution typing of the entire locus with a single tray. locus specific typing on a single tray reduces QC and testing costs while saving ...
Company:Dynal Biotech, LLC

Cw High Res SSP UniTray®

Description:... I Direct to High Res SSP kits provide high resolution typing of the entire locus with a single tray. locus specific typing on a single tray reduces QC and testing costs while saving ...
Company:Dynal Biotech, LLC

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Locus in Medical Definition

Autoimmune regulator

... Entrez 326 HUGO 360 OMIM *607358 RefSeq NM_000383.1 UniProt CAA08759 Other data locus Chr. 21 q22.3 The Autoimmune Regulator, abbreviated AIRE , is a human gene which is expressed in the thymus . It causes ...
Locus in Medical Dictionary

Prenatal

... development. The title of her doctoral dissertation is "The Effect of the Centering Prenatal Care Model on the Knowledge, Self-Esteem, Health locus of Control, and Perception of Participation and Satisfaction of Pregnant Women." ... ...
Locus in Biological News

Evolution of fruit size in tomato

... vary up to 30% as a result of variation at this locus alone. Cloning and sequencing of this locus reveals that the wild type protein codes for a ... locule numbers. Further comparisons of this locus across different tomato cultivars, including wild ...

Concentrating on different aspects of pain leads to breakthrough in migraine genetics

... study. Researchers identified one gene locus on chromosome 10q23, which showed significant ... as well as in the replication study. The gene locus was especially strongly linked to female ... Verneri Anttila from Paloties group. This locus is thus linked to migraine in a total of 4000 ...

Does the desire to consume alcohol and tobacco come from our genetic makeup?

... in females and 28% in males) use a common locus (an identifiable location on a chromosome) for ... with diastolic blood pressure (DBP), they found a locus for smoking. on chr 3, in the area ... involved with pre-math stress DBP, they found a locus for alcohol on chr 4, inside gene GRID2, ...

Did the North Atlantic fisheries collapse due to fisheries-induced evolution?

... reports steep changes in the frequency of genotypes at a single genetic locus with depth: a gradient of nearly one half percent drop in frequency per meter. The genotypes at the locus are directly related to behavioral types that select deep vs shallow water ...

New findings on immune system in amphibians

... characterized genetic variation and detected more than one MHC class II locus in a tailed amphibian. Unlike mammals, not much has been known until now ... the MHC has been studied, and the first one in which more than one MHC II locus has been found. The crucial role of the MHC in the immunity of ...

A tall story: New research adds to growing body of knowledge of genetics of height

... acting as switches to turn genes elsewhere in the genome on or off. One locus in particular is also implicated in osteoarthritis, the most common form ... involving the effects of wear and tear on the bodys structures. This locus reinforces a similar link identified by a previous study, and may be ...

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Locus in Biological Technology

China Medical Technologies Receives SFDA Approval for Its Bladder Cancer FISH Probe

... and monitoring the course of bladder cancer. It is designed to detect and identify whether aneuploidy for chromosomes 3, 7, 17 and loss of the p16 locus are present in the human bladder cells. A number of hospitals in China have applied the Probe for diagnosing patients with hematuria and have ...

Transgenomic Awarded SBIR Grant to Support Development of SURVEYOR(R) Endonuclease Adaptor-ligated Libraries (SEAL) for Determining Whole Genome Sequence Variation

... sequence context of the mutation. The library can be sequenced directly via standard or massively parallel systems, queried at any desired genetic locus by PCR amplification or archived for subsequent multi-query analysis. About Transgenomic Transgenomic is a global biotechnology ...

Transgenomic Introduces SURVEYOR(R) Endonuclease Adaptor-Ligated Libraries (SEAL) for Determining Whole Genome Sequence Variation

... sequence context of the mutation. The library can be sequenced directly via standard or massively parallel systems, queried at any desired genetic locus by PCR amplification or archived for subsequent multi-query analysis. About SURVEYOR SURVEYOR Mutation Detection Kits and the SURVEYOR Check-It ...

National Nanotechnology Initiative releases new strategic plan

... nanotechnology R&D. The NNI provides a vision of the long-term opportunities and benefits of nanotechnology. By serving as a central locus for communication, cooperation, and collaboration for all Federal agencies that wish to participate, the NNI brings together the expertise needed to ...

SNPs Powerful Tools for Association Studies

... generations. Typically, each STR locus is scored by PCR amplification with ... Each nucleotide repeat of different length at a locus is called an allele, and some loci can have more ... the genome, respectively, and an average locus heterozygosity of greater than 0.7. These ...

QIAGEN Multiplex PCR Handbook

... that alter the function of the gene locus of interest, for example by inactivating or ... are specific either for the wild-type locus or for the mutant locus. In Figure 1, one primer ... one primer is specific for the wild-type locus and the other specific for the mutant ...

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Locus in Biological Products

Mouse Anti-p14 ARF / p16Beta Ab-2 Mouse Monoclonal Antibody, Unconjugated, Clone 14P02 from Lab Vision

Description:... The INK4a-ARF locus encodes two unrelated proteins both of which function in tumor ... of p14^ARF^ and a C-terminal region of mdm2. Deletion of the ARF-INK4a locus simultaneously impairs both the INK4a-cyclin D/cdk4-RB and the ...
Company:Lab Vision

SNP Scoring Service from Polymorphic DNA Technologies, Inc.

Description:... Sanger dideoxy DNA sequencing, the gold standard in DNA analysis. We use high throughput capillary sequencing instrumentation. The polymorphic locus can be confirmed by sequencing in both directions. The use of DNA sequencing also provides sequence context information, further confirming the ...
Company:Polymorphic DNA Technologies, Inc.

Custom Oligo Assay Single Locus 1920 samples from Illumina

Description: ...
Company:
Locus in Biological Definition

Homozygote

... or polyploid and have the same alleles at a locus (position) on homologous chromosomes . When an ... dominant genotype occurs when a particular locus comprises two alleles for the dominant trait ... recessive genotype occurs when a particular locus comprises two alleles for the recessive trait ...

Locus

... The word locus (plural loci ) is Latin for "place". In biology and evolutionary computation , a locus is the position of a gene (or other significant sequence) on a chromosome . A locus can be occupied by any of the alleles of the ...

Allele frequency

... frequency is defined as follows: Given a) a particular chromosome locus , b) a gene occupying that locus, c) a population of individuals ... Example If there are ten individuals in a population and at a given locus there are two possible alleles, A and a , then if the genotypes of ...

Bacterial conjugation

... other genetic information, the F-plasmid carries a tra and a trb locus , which together are about 33 kb long and consist of about 40 genes . The tra locus includes the pilin gene and controlling genes, which together form pili ...

Evolutionary developmental biology

... fixation of a particular cellular or biochemical function at one locus , leaving the duplicated locus free to fulfill a new function. In contrast, changes in gene regulation , ...

Ewens's sampling formula

... from a population and classified according to the gene at a particular locus then the probability that there are a 1 alleles represented once ... under mutation and genetic drift and the role of selection at the locus in question is negligible, and (3) every mutant allele is novel. This is ...

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Locus in Biological Dictionary

Single locus probe

... A single locus probe is a DNA or RNA sequence that is able ... ... has been developed for the first single locus probe , the radioactivity on the ... DNA ... Problem Set 2. Problem 5: Alleles in a single - locus probe ... individual with a specific single ...

Quantitative trait loci

... genes and ... quantitative trait locus ( ′kwäntə′tādiv ¦trāt ′lōkəs ) ( genetics ) ... of a gene ... 2 Quantitative trait locus . 3 QTL mapping. 4 Analysis of ... ... ... What Is A Quantitative Trait locus ? Traditional quantitative genetic research ...

Polymorphic loci

... tried to ... Therefore, for any polymorphic locus , one of the alleles is from the mother and ... ... ... Wyman AR, White R. A highly polymorphic locus in human DNA. ... www.PharmCast.com is the ... for human identification and ... VWF2-a sub- locus was found to have five ... ... accurate ...

Multi-locus probe

... Multi - locus , probe ,biological ,biology dictionary,biology ... terms,biology abbreviations ... Multi - locus probe . A probe that hybrid izes to a ... ... the multi - locus probe approach, Jeffries devised a panel of ...

Locus

... locus (mathematics), the set of points satisfying a ... from "http://en.wikipedia.org /wiki/ locus " ... In the fields of genetics and evolutionary computation, a locus (plural loci) is a fixed position on a ...

Loci

... of genetics and evolutionary computation, a locus (plural loci ) is a fixed position on a ... A variant of the DNA sequence at a given locus is called an allele. ... The 'method ... a center or source, as of activities or power: locus of control. 3. Mathematics. ... ...

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Other Contents
(Date:4/17/2014)... San Diego School of Medicine report that older women, ... major loss are more likely to be compassionate toward ... published in this month,s issue of the International ... are associated with better health and well-being as we ... improve the outcomes of individuals whose deficits in compassion ...
(Date:4/17/2014)... the April issue of Immunity , Kevin J. ... Research, says it,s time to take a fresh look ... sepsis, which kills millions worldwide every year, including more ... into the bloodstream to fight an injury or infection ... maintaining good health without inflammation, wounds and infections ...
(Date:4/17/2014)... A Northwestern University synthetic biology team has created ... create programmable therapeutics that could travel the body ... disease. , Engineering cell-based, biological devices that monitor ... in clinical synthetic biology. However, no existing technology ... a patient,s physiological state and respond in a ...
(Date:4/17/2014)... MAYWOOD, Il. (April 17, 2014) Doctors who ... disease called lymphangioleiomyomatosis (LAM) can face an agonizing ... progression of the disease and help relieve shortness ... lung transplants, and sirolimus can cause potentially fatal ... said pulmonologist Dr. Daniel Dilling, medical director of ...
(Date:4/17/2014)... NY (April 16, 2014) The cause of neuronal ... new study proposes that neurons may be mistaken for ... system, similar to the way autoimmune diseases like type ... body,s cells. The study was published April 16, 2014, ... new, and likely controversial, idea in Parkinson,s disease; but ...
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(Date:4/17/2014)... Clemson professor Rajendra Singh Thursday as a "Champion ... expand solar deployment in the residential, commercial and ... Professor of Electrical and Computer Engineering and director ... a local hero leading the charge across the ... solar power and driving policy changes at the ...
(Date:4/17/2014)... on a novel method to help kidney stone ... effective treatment possible., Kidney stones represent a major ... If left untreated, apart from being particularly painful, ... complications. In many patients treated successfully, stone recurrence ... pathological approach to diagnosis and treatment needs to ...
(Date:4/17/2014)... researchers have detected new early-warning signs of the potential ... have far-reaching implications for the diagnosis and treatment of ... million Americans. , "We had not expected to see ... stages," said Ann Elsner, professor and associate dean in ... the study. "We set out to study the early ...
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