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Linkage in Medical News

Study finds genetic link to human herpes susceptibility

... sore susceptibility genes, the U researchers used linkage analysis, which traces genetic markers in ... whole-genome study of herpes simplex virus to use linkage analysis. The researchers studied 421 people ... who couldnt be categorized were excluded from the linkage analysis, as were the 111 mildly affected people. ...

Discovery suggests location of genes for breast density, a strong risk factor for breast cancer

... The study, the first reported genetic linkage analysis for genes influencing breast density, ... with the disease or trait of interest. Such linkage studies have been used to uncover many ... The Mayo researchers performed a genome-wide linkage scan to identify possible chromosome regions in ...

Oncogene inhibits tumor suppressor to promote cancer: Study links B-RAF and LKB1

... cell proliferation. "Taken together, our results provide a molecular linkage between the LKLB1-AMPK and the RAF-MEK-ERK pathways and suggest that ... clinical impact. "Further understanding of how the intriguing molecular linkage between LKB1-AMPK and RAF-MEK-ERK functions in tumorigenesis could ...

Virginia Tech researchers find human virus in chimpanzees

... at this time," said Kaur, but she admits that mounting evidence suggests a linkage between visiting scientists and tourists and the viruses that are ... endangered chimpanzee population. Scientific establishment of that linkage could affect the eco-tourism industry, which is an important source of ...

Reshaping pharmaceutical quality

... by design (QbD) principles. Design space discussions considered the linkage of the patient experience with product quality. The Control Strategy Team ... between patient and business requirements, as well as showing the linkage from critical quality attributes. The Legacy Products Team has started ...

Riley Hospital for Children & Capital Institute of Pediatrics become international sister hospitals

... Modeled on the concept of international sister cities, the formal linkage of hospitals in two countries is much rarer. As international sister ... pediatric lung disease other areas of initial focus of the Riley Capital linkage include pediatric endocrinology and pediatric neurology. I have been ...

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Linkage in Medical Technology

Revolution Health and EmergingMed Launch Cancer Clinical Trial Matching and Referral Service

... said Brad Jacobs MD, MPH, Senior Medical Director of Revolution Health. "EmergingMed's online matching service and health call center provide key linkage points for patients and their caregivers when looking for clinical trials." "EmergingMed is committed to providing personalized services ...

deCODE Obesity Study Sheds Light on How Genetics Affects Risk and Onset of Common Diseases

... into proteins -- have a major impact on several parameters of clinical obesity. The deCODE team then used its unique resources for genome-wide linkage and association analysis to demonstrate that variability in gene expression, like overall risk for disease, has a significant inherited component ...

Research Shows Decas Sweetened Dried Cranberries Pack Twice the Proanthocyanidin Punch as Cranberry Juice Cocktail

... to Ronald L. Prior, Ph.D. of the USDA Arkansas Children's Nutrition Center, cranberries have high antioxidant activity and a unique A-type PAC linkage structure that sets it apart from most other plants. "Brunswick Labs' data on the PAC content of SDCs shows levels much higher than originally ...

Exelixis Presents Encouraging Phase 1 Data For XL019, A Novel Selective Inhibitor of JAK2

... JAK2 is a critical target in myeloproliferative disorders, and effective inhibition of JAK2 may directly translate into clinical benefit. The strong linkage of JAK2 to MPDs provides a potentially quick route to market, with potential for additional opportunities in larger commercial indications. We are ...

The Pittsburgh Life Sciences Greenhouse Relocates Therapeutics Company to Pittsburgh

... and supports the growth of biosciences companies in southwestern Pennsylvania. The PLSG has investment and business growth programs to increase the linkage between research, technology and commercialization; nurture and develop entrepreneurial biosciences enterprises; grow the region's talent pool in the ...

Statement From The National Conclave on HIV/AIDS Policy for Black Clergy

... CA) that requires routine HIV testing upon entry and exit, counseling and HIV/AIDS treatment for federal inmates when medically indicated and linkage to care upon discharge. As we go forward on this historic gathering, we are determined to stand together in a renewed effort to realize the day when ...
Linkage in Medical Products

ABI PRISM 310 Genetic Analyzer

Description:... DNA analysis for any research, clinical, or forensic lab -- enables you to automate applications from de novo sequencing to SNP validation and linkage mapping. This versatile analyzer is so easy to use, that once it is installed and you have completed our short training course, all you have to do is ...
Company:Applied Biosystems

Clarus - Clinical Documentation

Features:... / order administration, intake and output, supply charge entry Flowsheet linkage to vitals, I & O and care plans Temperature, pulse and respirations with ... Pulse oximetry readings On-line entry of intake and output information linkage to IV flowsheet for automatic update Separate Surgical I & O Summary ...
Company:American HealthNet

Snap-In Snap-Out®-II Curved Mini Scissors Insert

Features:... Hand-finished jaw manufacturing Fully insulated shaft - tip Jaw linkage Lightweight stainless steel handles Five handle styles and sixteen interchangeable tip patterns Simple assembly and disassembly Lifetime ...
Company:GYRUS ACMI

Snap-In Snap-Out®-II Straight Scissors Insert

Features:... Hand-finished jaw manufacturing Fully insulated shaft - tip Jaw linkage Lightweight stainless steel handles Five handle styles and sixteen interchangeable tip patterns Simple assembly and disassembly Lifetime ...
Company:GYRUS ACMI

Snap-In Snap-Out®-II Curved Scissors Insert

Features:... Hand-finished jaw manufacturing Fully insulated shaft - tip Jaw linkage Lightweight stainless steel handles Five handle styles and sixteen interchangeable tip patterns Simple assembly and disassembly Lifetime ...
Company:GYRUS ACMI

Snap-In Snap-Out®-II Hook Scissors Insert

Features:... Hand-finished jaw manufacturing Fully insulated shaft - tip Jaw linkage Lightweight stainless steel handles Five handle styles and sixteen interchangeable tip patterns Simple assembly and disassembly Lifetime ...
Company:GYRUS ACMI
Linkage in Medical Definition

Sexual orientation and medicine

... ^ http://www.baphr.org/about/default.asp ^ Hamer, Hu, Magnuson, Hu and Pattatucci (1993) A linkage between DNA markers on the X chromosome and male sexual orientation. Science 261(5119): pp. 321-7. ^ Healthy People 2010, 2nd ed. "A Systematic ...
Linkage in Medical Dictionary

ACTH

... and ACTH -producing pituitary tumor s (Cushing's disease ). mitotic activity ... The amino acids are coupled by a peptide bond, a special linkage in which the nitrogen atom of one amino acid binds to the carboxyl carbon atom of another. Many peptides, such as the hormone s vasopressin and ...

Amino acids

... contains many enzyme s, vitamins , minerals and amino acids that your body needs. PEPTIDE ( ALS O POLYP EPTIDE): Biochemical formed by the linkage of up to about 50 amino acids to form a chain. Longer chains are called protein s. Animal sources such as egg whites, cheese, chicken, fish, ...

Cell

... Laryngitis Laryngotracheo bronchitis - acute Late persi stent Lyme disease Late syphilis Lateral epicondylitis ... A possible linkage of such reactions with specific T- cell responses to birch pollen antigen s in the blood and lesion al skin was examined as well. ...
Linkage in Biological News

Human genomics in China

... extent. The rise of other molecular "omics" further strengthened the linkage of "big science" and "small science". For such a tremendous impact of this linkage upon life science research and the development of biotechnology, it is ...

Research pushes back history of crop development 10,000 years

... biology." "This lengthy development should favour the close linkage of domestication syndrome trait genes which may become much more ... easier. Interestingly, as more crop genomes become mapped, the close linkage of two or more domestication syndrome genes has been reported on several ...

World-first to predict premature births

... of Melbourne recently received an Australian Research Council (ARC) linkage Grant of $390,000 to fund the project for three years. "We are creating ... have enabled us to develop early findings and attract funding through ARC linkage Grant scheme," Professor Roger Smith said. ...

Concentrating on different aspects of pain leads to breakthrough in migraine genetics

... locus on chromosome 10q23, which showed significant evidence of genetic linkage in both populations studied as well as in the replication study. The gene ... This study is the first international collaboration as well as the largest linkage study in migraine to date. It successfully applied new analysis strategies ...

Landon Foundation-AACR INNOVATOR Awards

... the villages. They will apply the AACR INNOVATOR grant to their study of linkage analysis to identify the predisposing gene or genes for mesothelioma among this cultural group and map the genetic risk factors by genetic linkage studies. Findings from this research have implications far beyond the ...

PRS And EmSense Partner To Integrate Bio-Sensory Measures In Packaging Research Studies

... - and to identify the specific design elements driving the recent failure of Tropicana's new packaging. These new insights, which help uncover the linkage between visibility, cognition, emotion and purchase, will now be available within PRS On-Shelf Packaging Assessment studies. Scott Young, ...

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Linkage in Biological Technology

DNA gripped in nanopores

... In this way they pulled the DNA molecule through a nanopore. The various dimensions of the holes offered them a direct look at the hydrodynamic linkage between DNA and the nanopore. The measurements revealed that the retarding forces exerted by the ions, slowly decreased if the DNA moved through a ...

PHARMORX Security Introduces New Technology Solutions for Counterfeiting, Grey Market Diversion, Track & Trace

... and services from the point of manufacture through to the consumer. Uniquely, PHARMORX provides solutions for unit level authentication and linkage to serialization at all levels of packaging. Our security offerings are customized, from simple labels and cartons with proprietary taggants to ...

Caliper Life Sciences and DiscoveRx Collaborate to Offer Solutions for Cell-Based GPCR Profiling and Lead Optimization

... (including sirtuins) proteases, phophatases and lipid modifying enzymes. The addition of cellular GPCR assays, which are a critical linkage in translational research, expands Caliper's in vitro-in vivo bridge and should provide our customers with enhanced ability to make more informed ...

The Pittsburgh Life Sciences Greenhouse Tops $10M in Company Investments

... in and supports the growth of biosciences companies in western Pennsylvania. The PLSG has investment and business growth programs to increase the linkage between research, technology and commercialization; nurture and develop entrepreneurial biosciences enterprises; grow the region's talent pool in the ...

The Pittsburgh Life Sciences Greenhouse Invests $100,000 in ParentPlus

... and supports the growth of biosciences companies in southwestern Pennsylvania. The PLSG has investment and business growth programs to increase the linkage between research, technology and commercialization; nurture and develop entrepreneurial biosciences enterprises; grow the region's talent pool in the ...

The PLSG Invests $115,000 in Innovention Technologies, LLC

... and supports the growth of biosciences companies in southwestern Pennsylvania. The PLSG has investment and business growth programs to increase the linkage between research, technology and commercialization; nurture and develop entrepreneurial biosciences enterprises; grow the region's talent pool in the ...

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Linkage in Biological Products

Genetic Mapping of Disease Genes from Promega

Description:... Edited by I.H. Pawlowitzki, J.H. Edwards and E.A. Thompson (1997) • This volume covers: linkage in dominant recessive and oligogenic disease, Model free (non-parametric) methods, Tools for gene mapping and ....
Company:Promega

Imject Maleimide Conjugation Buffer from Pierce Biotechnology, Inc.

Description:... prior to immunization) • A hapten-carrier conjugate is formed in just two hours • Results in a stable, covalent thio-ether linkage • Purified proteins, activated with sulfhydryl-reactive maleimide groups • Lyophilized in PBS, pH 7.2, containing ...
Company:Pierce Biotechnology, Inc.

Antisense oligonucleotides from Thermo Scientific

Description:... internucleotide linkages at the 3 and/or 5 end are synthesised as phosphothioates (PTOs) to prevent enzymatic degradation. Inverted end 3-3 linkage to prevent enzymatic degradation and chain elongation.Lit: J.F.R. Ortigao, H. Rosch, H. Selter, A. Frohlich, A. Lorenz, M. Montenarh, and H. Seliger, ...
Company:Thermo Scientific

Ph.D. Peptide Display Cloning System from New England Biolabs

Description:... Cloning System facilitates the display of custom peptide libraries on the surface of bacteriophage M13 as coat protein fusions, creating a physical linkage between each displayed peptide and its encoding DNA sequence. Peptide ligands for a variety of targets can then be selected by the straightforward ...
Company:New England Biolabs
Linkage in Biological Definition

Classical genetics

... classical genetics in eukaryotes , was genetic linkage . The observation that some genes do not ... to a location on the chromosomes . linkage maps are still used today, especially in breeding ... to as molecular genetics . See also : Genetic linkage ...

Genetic recombination

... process by which alleles at two genes in a linkage group can become separated. In this process ... is less than if they were farther apart. Genetic linkage describes the tendency of genes to be inherited ... result of their location on the same chromosome. linkage disequilibrium describes a situation in which ...

Gregor Mendel

... Erich von Tschermak . His results were quickly replicated, and genetic linkage quickly worked out. However, a period of tense argument ensued over its ... censored his results, otherwise he would have stumbled across genetic linkage . The standard botanical author abbreviation Mendel is applied to ...

Hardy-Weinberg principle

... 1 Assumptions 2 Causes of deviation 3 Derivation 4 Sex linkage 5 Generalizations 5.1 Generalization for more than two alleles ... in which case, equilibrium is reached in two generations. Sex linkage Where the a gene is sex-linked , the heterogametic sex (e.g. males in ...

Chromosomal crossover

... be expected to cross over three or four times during meiosis. This aids evolution by increasing independent assortment, and reducing the genetic linkage between genes on the same chromosome. The physical basis of crossing over was first demonstrated by Harriet Creighton and Barbara McClintock in ...

DNA

... it is far from certain that the B-form double helix is the dominant form in living cells. Direction of DNA strands The asymmetric shape and linkage of nucleotides means that a DNA strand always has a discernible orientation or directionality. Because of this directionality, close inspection of a ...

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Linkage in Biological Dictionary

LOD score

... ... Lod Score Method of Estimating linkage Distances ... The following is the formula for ... the largest lod score corresponds to a linkage ... Online Medical Dictionary and glossary ... obtained from single-marker variance component linkage analysis ... Figure 2 shows the LOD score of ...

Linkage map

... the first genetic map , also called a linkage map . ... linkage mapping is critical for identifying the ... draw ... Genetic vs. Physical Maps . Genetic linkage and Genetic Maps . The Background ... Mapping ...

Linkage equilibrium

... In population genetics, linkage disequilibrium is the non-random association of ... on the same chromosome. It is not the same as linkage , which describes the association of two or more loci on a chromosome with ... linkage disequilibrium ( ¦liŋkij dis′ēkwə′librēəm ) ( ...

Linkage group

... Genetic linkage occurs when particular genetic loci or ... genetically linked. This is called autosomal linkage ... linkage group n. A pair or set of genes on a ...

Linkage disequilibrium

... In population genetics, linkage disequilibrium is the non-random association of ... on the same chromosome. It is not the same as linkage , which describes the association of two or more loci on a chromosome with ... linkage disequilibrium ( ¦liŋkij dis′ēkwə′librēəm ) ( ...

Linkage

... Genetic linkage occurs when particular genetic loci or ... genetically linked. This is called autosomal linkage ... A mechanical linkage is a series of rigid links connected with joints ...

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