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Lineage in Medical News

Weizmann Institute scientists' new technique gets to the root of cancer

... a cell's path of descent, called a cell lineage tree, is shared by many branches of biology and ... Therefore, by reconstructing a cancer cell lineage tree and performing an analysis of mutations ... a subset of cells characterized by distinct lineage features (e.g. greater depth)?' So far, their ...

Microenvironment a main driver of aggressive multi-lineage leukemia disease type

... aggressive group of blood cancers known as mixed lineage leukemias (MLL) and how the disease might be ... chronic myelogenous leukemia (CML). Mixed lineage leukemia (MLL) results when chromosome mutations ... adaptability of the leukemia stem cell in mixed lineage leukemia. "Our findings underscored that ...

Globetrotting black rat genes reveal spread of humans and diseases

... the Mekong Delta, and Indonesia. The Indian lineage spread to the Middle-East around 20,000 years ... during the Age of Exploration. The East Asian lineage moved from Taiwan to Japan, the Philippines, and ... a good match between the historic spread of each lineage and ancient routes of human migration and trade, ...

JCI online early table of contents: Jan. 2, 2008

... not just in bone cells of the osteoblast lineage and there are conflicting reports as to whether defects in cells other than osteoblast lineage cells are involved in the disease that manifests ... that mutation of Phex only in osteoblast lineage cells recapitulates the disease observed in ...

New genetic lineage of Ebola virus discovered in great apes

... and 2001, appear to belong to a single genetic lineage originating from the first epidemic documented in ... the seven primates belonged to a new genetic lineage of ZEBOV. This lineage, named B, showed 2 to 3% genetic divergence from lineage A, the one in which scientists had hitherto ...

Bcl6 gene sculpts helper T cell to boost antibody production

... the molecular programming of Tfh establishes it as the fifth distinct lineage of helper T cell. Dong and colleagues will continue to characterize Tfh ... Th17 cell, which he and colleagues identified as the third T helper cell lineage when conventional wisdom held that there were only two such lines. They ...

Scientists Identify Key Gene That Protects Against Leukemia

... HSCs are proliferating and the rate of differentiation toward the myeloid lineage that ultimately results in leukemia. The striking analogy inspired the ... JunB-deficient mice consistently displayed higher levels of myeloid lineage than the control group, indicating constant regeneration of a ...

Course of West Nile Infection Charted

... case study also highlights that this strain of the virus, West Nile virus lineage 2, which is endemic to Southern Africa, may cause severe disease and ... Venter added. "This contradicts the general belief that West Nile Virus lineage 2 only causes mild disease but rather suggests that it may be an ...

Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution

... a tunicate, was previously thought to belong to the the earliest chordate lineage because of the sea squirt's very simple body plan. Comparison of the lancelet, sea squirt and human genomes, however, show instead that the lancelet lineage diverged before the tunicates and vertebrates. "Sea squirts and their ...

Children's Hospital scientists identify possible target for prevention and treatment of pneumonia

... IL-22 and interleukin 17A (IL-17A) are produced by a recently discovered lineage of cells known as T Helper Type 17 (Th17). Childrens researchers found evidence that the Th17 cell lineage and its cytokines IL-22 and IL-17A have evolved to promote host defense ...

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Lineage in Medical Products

Lineage Acetabular Cup System (Metal)

Description:... The lineage acetabular system with metal liners uses sophisticated manufacturing methods and materials to minimize wear debris ....
Company:Wright Medical Technology, Inc.

Lineage Acetabular Cup System (Ceramic)

Description:... The lineage acetabular system with ceramic liners uses sophisticated manufacturing methods and materials to minimize wear debris ....
Company:Wright Medical Technology, Inc.

Lineage Acetabular Cup System (Polyethylene)

Description:... The lineage acetabular system with UHMWPE liners provide lipped options for increased femoral head coverage promoting a stable ....
Company:Wright Medical Technology, Inc.
Lineage in Medical Definition

Thymocyte

... Beta selection 2.3 Positive selection and lineage commitment 2.4 Negative selection ... events Double negative 1 or ETP (Early T lineage Progenitor) Lineage- CD44 + CD25 - CD117 + ... die by apoptosis. Positive selection and lineage commitment Thymocytes which pass "beta ...

Central tolerance

... apoptosis ) Anergy (non-responsiveness) Receptor editing (changing the specificity of the autoreactive cell) [4] Division to a regulatory lineage Genetic defects in these processes lead to autoimmunity, such as in the human syndromes APS-1 and IPEX . References ^ ...
Lineage in Medical Dictionary

Immunology

... cell , a cell that can "present" antigen in a form that T cells can recognize it. Among the APCs are B cells and cells of the monocyte lineage including macrophage s. Search All of MedicineNet For: search help ... Immunology Program What is X-linked agammaglobulinemia ? X-linked ...
Lineage in Biological News

Little teeth suggest big jump in primate timeline

... remains ever found of anthropoids, the primate lineage of today's monkeys, apes and humans, say ... exciting because they show that the anthropoid lineage is much more ancient than we realized." In ... only Anthrasimias's is part of the anthropoid lineage that evolved into modern monkeys, apes and ....

Field Museum paleontologist leads study on two new dinosaurs from China

... of ornithomimosaur, or ostrich-mimic dinosaur. Ornithomimosaurs are a lineage of theropods that evolved a toothless beak and were likely omnivorous or ... the environmental sorting of animals and the very stable, but depauperate, lineage composition of Cretaceous Central Asian dinosaur faunas that reined for ...

2009 ASPB Summer Undergraduate Research Fellowship award announcement

... State University Mentor: Patricia Bedinger Analysis of an Emerging lineage of Wild Tomato I can't express how grateful and excited I am to be a SURF recipient. My project is evaluating a possible diverging lineage of a marginal population of the wild tomato species, Solanum habrochaites. ...

Scientists identify key gene that protects against leukemia

... HSCs are proliferating and the rate of differentiation toward the myeloid lineage that ultimately results in leukemia. The striking analogy inspired the ... JunB-deficient mice consistently displayed higher levels of myeloid lineage than the control group, indicating constant regeneration of a ...

Genome of simplest animal reveals ancient lineage, confounding array of complex capabilities

... whole genome analysis supports placing the placozoans after the sponge lineage branched from other animals," said Daniel Rokhsar, the publication's ... another 13 placozoan species in order to identify the most basal placozoan lineage and genome," said Schierwater. "Trichoplax is an ancient lineagea good ...

Duck-billed platypus genome sequence published

... genome of the platypus, whose ancestors split from the rest of mammalian lineage some 166 million years ago, with the well-characterized genomes of the ... which had been passed on from ancestral reptile genomes. The reptilian lineage displays a similar duplication of venom genes, but that duplication ...

Bizarre walking bat has ancient heritage

... in a report published in the journal BMC Evolutionary Biology. "The lesser short-tailed bat seems to be the sole survivor of an ancient Australian lineage now found only in New Zealand," says Dr Hand. "This study shows that, contrary to existing hypotheses, bats are not overwhelmingly absent from the ...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

... a single DNA nucleotide change which resulted in a mutation in the most conserved region of the protein. Of the 45 individuals within the affected lineage who inherited the mutation, 33 have developed PGL2, providing strong evidence that hSDH5 is the PGL2 gene. The seven individuals who inherited the ...

T-STAR grant funds genetic studies on shrimp and papaya and endangered cycad rescue

... a pressing horticultural problem, an acute invasive species crisis, fundamental questions concerning pollinator-plant interactions in an ancient lineage of plant, and critical gaps in knowledge needed to steer urgent conservation decisions," says Marler. "WPTRC scientists in partnership with ...

Mouse model provides clues to human language development

... in the mouse phenotype. The study of the Foxp2 mice was funded within the scope of the National Genome Research Network (NGFN). As with each mouse lineage studied in the German Mouse Clinic, the Helmholtz scientists analyzed the Foxp2 mice by screening for more than 300 parameters, including the ability ...

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Lineage in Biological Technology

Growing Interest in DNA-Based Genetic Testing Among African American with Historic Election of President Elect Barack Obama

... Presidency: President-Elect Obama's paternal lineage is rooted in Kenya on Africa's eastern coast. ... ancestry tracing company that pioneered African lineage matching in the United States utilizing its ... descent. Since its inception, African Ancestry's lineage reveals have impacted the lives of more than ...

Families Embrace Science/Technology-based Ancestry Tracing Marking Milestone in Black Family Reunion Celebrations Across the Nation

... employ science-based analyses. The accuracy in lineage matching is dependant upon the size and sampling ... ancestry tracing company that pioneered African lineage matching in the United States utilizing its ... Since its inception, African Ancestry's lineage reveals have impacted the lives of more than ...

African Ancestry, Educators, Identity Experts Launch DNA Education Project during Historic Black History Month; 7th Graders Score High on Ultimate Self Test

... Ancestry, Inc. is the ancestry tracing company that pioneered African lineage matching in the United States utilizing its proprietary DNA-database of ... for people of African descent. Since its inception, African Ancestry's lineage reveals have impacted the lives of more than 100,000 people in the U.S. ...

DNA Diagnostics Center Offers Father's Day DNA Testing

... Diagnostics Center also offers Y-chromosome testing that can answer the question, "Where did my dad's ancestors begin?" DNA can trace male lineage back tens of thousands of years, and any man can find out where his paternal ancestors started--was it the foothills of the Himalayas, or Sub-Saharan ...

Use it or lose it? Researchers investigate the dispensability of our DNA

... that are shared between primates and closely related mammals, were present in the ancestor of modern rodents, but have been lost in the rodent lineage more recently. The researchers found that the genomic evidence supports an important biological role for ultraconserved elements, as well as ...

New 40th Edition of Gray's Anatomy Celebrates 150 Years as the World's Preeminent Anatomical Reference

... of its 150th anniversary, the new edition provides meticulously enhanced and updated artwork throughout, while maintaining the distinguished lineage of the original. With more than 200 completely new radiologic, CT, MR and other imaging studies vividly capturing anatomy as it is seen only by ...

DNA Heritage Success in Patent Battle Helps Keep Genealogy DNA Test Prices Low

... can both be fed into an in-house and public-access Ybase database. These have become invaluable tools for those researching their direct male lineage and surname. About the company: Established in 2002, DNA Heritage provides advanced genetic tests to the genealogy community and those tracing ...

Gladstone scientists identify role of tiny RNAs in controlling stem cell fate

... had not previously been determined. The Gladstone team showed that miRNAs can control how pluripotent stem cells determine their fate, or cell lineage in this case as cardiac muscle cells. Specifically, they found that miR-1 and miR-133 are active at the early stages of heart cell formation, ...

CombiMatrix and Clarient Collaborate to Market, Sell Novel Genomics-Based Test for Chronic Lymphotic Leukemia (CLL)

... growing lymphoma/leukemia business and as part of our continued focus on personalized medicine." CLL is the most common form of the B-cell lineage lymphoproliferative disorders, accounting for about 30 percent of all cases in the USA and Europe. In the U.S. alone, there are greater than 10,000 ...
Lineage in Biological Products

rNeural Stem Cell (rNSC)Kit from AlphaGenix, Inc.

Description:... Rat neural stem cell kits are intended for the in vitro growth and commitment to neuronal and glial lineage differentiation, of cultured fetal rat neural stem and progenitor cells expanded using ....
Company:AlphaGenix, Inc.

Human / Mouse / Rat Blood Vessels (CD31 / Von Willebrand Factor (vWF)) IHC staining Kit from CHEMICON

Description:... Factor antibody reacts specifically with the endothelial cells of blood vessels and is a useful marker for the identification of endothelial lineage in tumors. It is important to note that not all endothelial cells synthesize von Willebrand factor, therefore a small percentage of these ...
Company:CHEMICON

Mouse Dopaminergic Neuron Differentiation Kit, 2nd Generation from R&D Systems

Description:... studies might facilitate the in vitroexamination of various aspects of neural development, in particular the underlying mechanisms controlling cell lineage and fate commitment. DESIGN OF THE KIT The Mouse Dopaminergic Neuron Differentiation Kit is a system designed for in vitroneural differentiation of ...
Company:R&D Systems

NeuroCyte - Rat Neural Stem Cell Kit from Orion BioSolutions, Inc.

Description:... Neural Stem Cell Kit with Medium High quality ready-to-use cryopreserved neural stem cells (NCSs) complete with optimized base medium for growth and lineage commitment. Just thaw and plate these unique cells generated from E18 fetal rat brain in the format you need for a tissue-like mixture of in vitro ...
Company:Orion BioSolutions, Inc.
Lineage in Biological Definition

Parthenogenesis

... produce offspring. This means that an asexual lineage will have roughly double the rate of population ... particularly defenseless against it, an asexual lineage is more likely to be completely wiped out by it. In contrast, a lineage that reproduces sexually has a higher probability ...

Species

... a group of organisms that shares an ancestor; a lineage that maintains its integrity with respect to ... species concept. Both agree that a species is a lineage that maintains its integrity over time, that is ... it), is reproductively isolated (else the lineage would merge into others, given the chance to do ...

Apoptosis

... in genetics and in the development of the nervous system, but cell lineage and differentiation inevitably led to the study of cell fate: "One aspect of the cell lineage particularly caught my attention: in addition to the 959 cells generated ...

Human

... difference of less than 1 per cent. It has been estimated that the human lineage diverged from that of chimpanzees about five million years ago, and from ... seven million years old already showing a divergence from the ape lineage suggests an earlier divergence. Human evolution is characterized by a ...

Alga

... 70 m in length ( kelps )—the red algae , and the green algae . The most complex forms are found among the green algae (see Charales ), in a lineage that eventually led to the higher land plants. The point where these non-algal plants begin and algae stop is usually taken to be the presence of ...

Bone

... They contain alkaline phosphatase - a chemical which has a role in the mineralisation of bone. Bone Lining Cells (BLCs) share a common lineage with osteogenesis (bone forming) cells. They function as a barrier for certain ions, induced osteogenetic cells. They are flattened, mononucleate ...

BLAST

... faster. Examples of other questions that researchers use BLAST to answer are Which bacterial species have a protein that is related in lineage to a certain protein whose amino-acid sequence I know? Where does the DNA that I've just sequenced come from? What other genes encode ...

Cryptozoology

... fossil " believed to have been extinct for 65 million years, was caught in a fishing net in 1938 off the coast of Africa . Of an even older lineage than the coelacanth are the Graptolites . Living representatives were first found in 1882 , although the group had previously been presumed to have ...

Endosymbiont

... Bacterial endosymbionts in echinoderms: Subcuticular bacteria from the brittle star Ophiactis balli (Echinodermata: Ophiuroidea) represent a new lineage of extracellular marine symbionts in the alpha subdivision of the class Proteobacteria. Burnett, W J and J D McKenzie ...

Endosymbiont

... Bacterial endosymbionts in echinoderms: Subcuticular bacteria from the brittle star Ophiactis balli (Echinodermata: Ophiuroidea) represent a new lineage of extracellular marine symbionts in the alpha subdivision of the class Proteobacteria. Burnett, W J and J D McKenzie ...

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Lineage in Biological Dictionary

Lineage

... lineage (video game), medieval fantasy massively multiplayer online role-playing ... " lineage " (Angel), a 2003 episode of the television series Angel " ... lineage is a medieval fantasy massively multiplayer ...

Anagenesis

... (scientific theory): Evolution within a lineage and by lineage splitting ) Evolution can take place by ... within a lineage, or by cladogenesis, in which a lineage splits into two ... Information about ...

Rhodophyta

... (PDF) ... The Rhodophyta (red algae) are a distinct eukaryotic lineage characterized by ... Introduction to the Rhodophyta . UCMP Berkeley, ... of Life ... The Rhodophyta (red algae) are a distinct eukaryotic lineage characterized by ... Online Shopping at DirectTextBook.com - Save up ...

True-breeding

... sources. ... How can you get a true breeding plant? Read ... ... recognized strain established by breeding individuals of unmixed lineage ... farm animals also have true - breeding breeds and breed registries, particularly ... Albino Burmese is dedicated to breeding the ...

Retrotransposons

... in the complete S. cerevisiae ... 2001 Drosophila euchromatic LTR retrotransposons are much younger than the host ... ... mag lineage of the Ty3/gypsy group of LTR retrotransposons in Anopheles gambiae. ... of the Ty3/gypsy group of LTR retrotransposons in Anopheles gambiae. ......

Purkinje fibers

... differentiation of Purkinje fibers in vivo and ET-dependent ... The definite mapping of Purkinje fiber progenitor cells to a myocyte lineage (3) ... Shotgun Histology Heart Purkinje Fibers . Shotgun Histology Heart Purkinje Fibers ... Shotgun Histology Heart Purkinje Fibers . ...

MtDNA

... most clear-cut Germanic mtDNA type within group J is type J/ 16231. ... mtDNA Haplogroup Migration Map from FTDNA (2006) ... Native American lineage and mtDNA Haplogroups Yahoo Group ... Eve book named this mtDNA haplogroup Helena. ... Genome database of polymorphisms and mutations of the ...

Micromere

... . ... ... features of the successive developmental stages in the micromere lineage. ... the specification of the skeletogenic micromere lineage of the sea urchin embryo. ... PLoS Biology is an open-access, peer-reviewed journal that features works of exceptional significance in all areas ....

Mammals

... are characterized by sweat glands, hair, three middle ear bones used in hearing, and ... The evolution of mammals within the synapsid lineage was a gradual process that took approximately 70 million years, beginning in the mid-Permian. By the mid-Triassic, there were many species that ...

Humoral immunity

... Humoral Immune Response (HIR) is the aspect of immunity that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineage (B cell). B Cells transform into plasma cells which secrete antibodies. The co-stimulation of the B cell can come ... humoral ...

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