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Intradermal in Medical News

Sanofi-aventis Announces Good First-quarter 2009 Performance

... (R) , the first influenza vaccine to be administered using a novel intradermal microinjection system. The benefits of this vaccine, in particular its ... events after abdominal surgery; -- the intradermal influenza vaccine Intanza(R) in Europe, and the pandemic ...

TorreyPines' NGX426, an Oral AMPA/Kainate Receptor Antagonist, Meets Primary Endpoints in Reducing Capsaicin-Induced Pain in Healthy Subjects

... normally non-painful stimuli to the skin) compared to placebo following intradermal injections of capsaicin in a human experimental model of cutaneous pain, ... subjects. Using a three-period cross-over design, subjects received two intradermal injections of capsaicin at 30 minutes and 120 minutes after administration ...

1st EMEA application filed for product using innovative intradermal microinjection system BD Soluvia

... safety and the ability to generate an immune response of the novel intradermal (ID) influenza vaccine. Compared with intramuscular (IM) injection, ID ... BD is deeply committed to continuing the development of BD Soluvia for the intradermal route of administration for use with infectious disease and emerging ...

Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

... genetically modifying autologous antigen-loaded dendritic cells to express an inducible costimulatory CD40 (iCD40) receptor. Twenty-four hours after intradermal administration, these genetically modified dendritic cells are activated in draining lymph nodes by intravenous administration of AP1903, a ...

TorreyPines Therapeutics Announces Management Change and Second Quarter 2008 Financial Results

... NGX426 on hyperalgesia, an abnormally increased pain state, and allodynia, pain resulting from normally non-painful stimuli to the skin, induced by intradermal injections of capsaicin. This study, if successful, will allow the company to further benefit from of the versatility of NGX426. -- Presented data ...

Therapeutic DNA Vaccine Company Inovio Biomedical Reports Second Quarter 2008 Financial Results

... plasmid DNA-based universal influenza vaccine candidates using the company's proprietary electroporation delivery technology and, specifically, a new intradermal device, showed that 100% of immunized mice given a lethal challenge of highly pathogenic H5N1 influenza virus (A/Vietnam/1203/04) survived and showed ...

Johnson & Johnson Reviews Growth Strategies for Medical Devices & Diagnostics and Consumer Businesses

... PRINEO(TM) Skin Closure System is a new product designed to reduce skin closure time an average of 75 percent compared to standard intradermal suturing in procedures such as body contouring, which some patients choose after having experienced significant weight loss. PRINEO was ...

Anesiva Announces Hiring of Sales Force for FDA-Approved Product Zingo(TM)

... hospital-focused sales force to support the commercial introduction of Anesiva's FDA-approved Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, in the second quarter of 2008. "By adding a sales force and sales leadership team with substantial hospital sales experience to ...

Anesiva Announces Upcoming Webcasts and Conference Participation

... of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in ...

Anesiva to Announce Third Quarter 2007 Financial Results and Host Webcast Conference Call on November 1, 2007

... of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in ...
Intradermal in Medical Technology

Halozyme Therapeutics Presents Findings on Combinations of rHuPH20 Enzyme With Bisphosphonates at the American Association for Cancer Research Conference

... Key findings from the study were as follows: -- In rodent intradermal models, injection of bisphosphonates without rHuPH20 created ... and ulceration in a concentration dependent manner. -- In rodent intradermal models, the maximal concentration of bisphosphonates that could be ...

Anesiva Announces Pivotal Phase 3 Trial of Zingo(TM) Meets Primary Endpoint and Significantly Reduces Venous Access Pain in Adults

... those treated with Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system compared to placebo (p= 0.003). Patients received Zingo ... product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access ...

Karolinska Institutet to Test Vical's Vaxfectin(R) Adjuvant With Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

... The proposed KI/SMI study would mark the first human test of a Vaxfectin(R)-formulated vaccine delivered by needle-free injection into the skin. intradermal delivery by needle-free injection and use of the Vaxfectin(R) adjuvant may increase the immune responses to the vaccine. About Vaxfectin(R) ...

Karolinska Institute to Test Vical's Vaxfectin(R) Adjuvant with Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

... proposed Karolinska/SMI study would mark the first human test of a Vaxfectin(R)-formulated vaccine delivered by needle-free injection into the skin. intradermal delivery by needle-free injection and use of the Vaxfectin(R) adjuvant may increase the immune responses to the vaccine. About Vaxfectin(R) ...

TorreyPines Therapeutics Initiates Clinical Trial to Evaluate Analgesic Effect of Oral Prodrug of Tezampanel

... NGX426 on hyperalgesia, an abnormally increased pain state, and allodynia, pain resulting from normally non-painful stimuli to the skin, induced by intradermal injections of capsaicin. The primary endpoint is subject self-report of spontaneous pain following the injection of capsaicin. "We believe there is ...

Cell Genesys Reports Association Between Immune Response and Patient Survival in Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer

... CSF (granulocyte-macrophagecolony-stimulating factor), an immune stimulatory cytokine, and then irradiated for safety. GVAX is administered via intradermal injections on an outpatient basis. To date, over 600 patients have been treated with GVAX cancer immunotherapies in Phase 1 and Phase 2 clinical ...

Interim Analysis Supports Continuation of Cell Genesys' VITAL-1 Phase 3 Clinical Trial of GVAX Immunotherapy for Prostate Cancer

... colony stimulating factor), an immune stimulatory hormone, and then irradiated for safety. GVAX is designed to be administered through intradermal injections on an outpatient basis. To date, over 600 patients have been treated with GVAX cancer immunotherapies in Phase 1 and Phase 2 clinical ...

Anesiva Defines Regulatory Pathway for Adlea with FDA

... of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in ...

Anesiva Initiates Phase 2 Trial with Adlea(TM) for Pain Relief Following Total Hip Replacement Surgery

... of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in ...

Anesiva Initiates New Phase 2 Trial of Adlea(TM) for Pain Relief Following Knee Replacement Surgery

... of novel therapeutic treatments for pain. The company has one FDA-approved product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access procedures in children three to 18 years of age. The second product in ...
Intradermal in Medical Dictionary

Intradermal

... intradermal tests are a type of skin test. An agent (such ... into the skin to test the reaction to it. intradermal tests are much used to diagnose allergy and to test cellular immunity . intradermal allergy test reactions Skin testing, PPD (R ...

Osler

... (Janeway lesion s) Paleness Nail abnormalities ( splinter hemorrhages under the nails) Joint pain Abnormal urine color Red, painful intradermal nodes in the pads of the fingers and toes called Osler 's nodes ... ...

Percutaneous

... continuum; percuss; percussion ; percussion sound; percussion wave; percussor; percutaneous ; ... There are two forms: percutaneous and intradermal . In percutaneous or prick testing, allergen solutions are placed on the skin , and the skin is then pricked with a needle, allowing the ...

Sarcoidosis

... is tuberculosis , but histoplasmosis , sarcoidosis , and blasto mycosis can also attack the gland . Kveim and Kveim-Siltzbach skin test intradermal injection , diagnostic test for sarcoidosis . Source: CHORUS/Kveim. Secondary pulmonary hypertension may be due to congenital heart ...

Scratch test

... the forearm, upper arm, or the back), ... Scratch test ing, in which the skin is scratched instead of puncture d, is used less often. intradermal testing involves directly injecting allergen solutions into the skin . in which different antigen s (substances that cause an allergic ...

Skin

... TEST (TST): A purified protein derivative of the tubercle bacilli, called tuberculin , is introduced into the skin by scratch, puncture , or intradermal injection . MORPHEA - A skin lesion that is characterized by the presence of localized, indurated, slightly depressed areas of thickened ...

Tuberculin

... TEST (TST): A purified protein derivative of the tubercle bacilli, called tuberculin , is introduced into the skin by scratch, puncture , or intradermal injection . Diagnosis is made by a tuberculin skin test. It can be confirmed by X rays of the chest and sputum examination. Ideally, ...

Tubercle

... TEST (TST): A purified protein derivative of the tubercle bacilli, called tuberculin , is introduced into the skin by scratch, puncture , or intradermal injection . PECTINEUS - ORIGIN: Pectineal line & Pubis , between iliopubic eminence and tubercle INSERTION: Pectineal line of femur ACTION: ...

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Intradermal in Biological Technology

Helix BioPharma Receives Approval to Initiate Phase II Pharmacokinetic Clinical Study of Topical Interferon Alpha-2b in Patients with Low-Grade Cervical Lesions

... favored due to the fact that conventional administration requires painful intradermal injection by a medical professional. Furthermore, intradermal injection is restricted to visible lesion administration, while HPV ...

Anesiva Outlines Comprehensive Commercialization Plan for FDA Approved Product Zingo(TM)

... launch plans for Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access ... product, Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain associated with peripheral venous access ...

First Multiple Dose Clinical Trial of TorreyPines Therapeutics' Oral Compound NGX426 Demonstrates Compound Is Safe and Well-Tolerated

... (abnormally increased pain state) and allodynia (pain resulting from normally non-painful stimuli to the skin) compared to placebo following intradermal injections of capsaicin in a human experimental model of cutaneous pain, hyperalgesia and allodynia. In order to pursue the Phase II clinical ...

Vaxfectin(R)-formulated Measles DNA Vaccine Could Address Unmet Need for Infants

... peaked at Week 5, and remained well above the accepted protection threshold for more than one year, with no difference noted between intramuscular or intradermal routes of administration. In the infant macaques, neutralizing antibody levels exceeded the accepted protection threshold prior to the second ...

Anesiva Announces First Quarter 2008 Financial Results

... March 31, 2008 and provided an update on its commercialization activities for FDA-approved Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, as well as clinical development milestones for Adlea(TM), the company's long-acting, localized, non-opioid analgesic drug ....

Anesiva Announces Expansion of Zingo Agreement in Europe

... distribution agreement for Zingo(TM) with Sigma-Tau SpA to include additional European countries. Zingo (lidocaine hydrochloride monohydrate) powder intradermal injection system is approved in the United States to provide topical local analgesia prior to peripheral IV insertions or blood draws in children ...

Anesiva Announces New Zingo Marketing and Distribution Agreement

... and distribution agreement, with Green Vision Company, for several Middle Eastern countries. Zingo (lidocaine hydrochloride monohydrate) powder intradermal injection system is approved in the U.S. to provide topical local analgesia prior to peripheral IV insertions or blood draws in children three to 18 ...

ProMetic presents preclinical data for prostate and pancreatic cancer at the AACR Meeting

... ProMetic's Director of Research and Development, Biology, presented preclinical data on the PBI-0110 alone and in combination with gemcitabine in intradermal and orthotopic pancreatic cancer. The study showed that PBI-0110 alone significantly inhibited pancreatic tumor growth in mouse models by as much as ...

Anesiva Announces Fourth Quarter and Year-End 2007 Financial Results and Provides 2008 Outlook

... and outlined its objectives for 2008 based on commercialization plans for FDA-approved Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, as well as clinical development milestones for Adlea(TM), the company's long-acting, localized, non-opioid analgesic drug ....

Microfabrica Introduces Set of Miniature 'Building Blocks' for Minimally-Invasive Medical Devices

... for distal protection or retrieval, especially in tortuous vessels, due to its unusual flexibility. Meanwhile, robust, hollow microneedles can enable intradermal and precision drug delivery systems." EFAB technology differs from conventional manufacturing processes in several ways. By applying to mechanical ...
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