W.M. Keck Foundation funds study of friendly microbes
...he genomes of "friendly" bacteria that inhabit the intestine and identifying the natural metabolic products tha...ting microbial communities along the length of the intestine and sequencing the genomes of new species, without having to culture them in test tubes. They are a...Highly adaptable genome in gut bacterium key to intestinal health
...iewed as a 'microbial organ' that lives within the intestine and harvests, stores and redistributes energy from the diet." Because changes in the composition of this "microbial organ" may be deleterious to human health, it is important to understand how gut microbes adapt to the dynamic environment of the gut...A frog's life is food for thought
...orphology is virtually unparalleled with the small intestine having increased in mass by 450 percent within just 36 hours." The results of Ms Cramp's study could have important implications for human survival. "Human survivors of starvation can endure the horrific and often fatal effects of re-feeding after ...Iron exporter revealed that may explain common human disorder
...y obtain iron from their mothers. After birth, the intestine absorbs dietary iron and releases it into the bloodstream where developing red blood cells incorporate the iron into hemoglobin. When red blood cells die, macrophage cells consume them and recycle the iron they contain. Macrophages and liver cells al......om six different anatomical sites inside the large intestine as well as a stool sample. Eckburg and his team d...bial communities differ among locations within the intestine as well as among different people. "We were surprised at the degree to which an individual determin...Rabbit Anti-ZO-1 (N-term) Monoclonal Antibody,, Clone ZMD.437 from Invitrogen
...terminal tissues Human pancreas prostate and small intestine tissues). Applications: Western blotting Immunofluorescence* Immunohistochemistry (froz) [*This antibody is recommended over Cat. No. 61-7300 for immunofluorescence.]...Protect RNA and Improve Target Cell Identification
.... Consecutive sections from human small intestine (20X magnification) were stained according to manufacturers' instructions. Cresyl Violet (Basic Nuclear Stain) Cresyl Violet is a basic synthetic dye that binds acidic components s...Development of Radioligand Binding Assays for the Motilin Receptor Using ScreenReady Targets.
...peptide secreted from endocrine cells of the small intestine that stimulates gastrointestinal contractility (Tonini et al ., 1996). The receptor for motilin has been cloned recently (Feighner et al ., 1999) and belongs to the GPCR family. Development of motilin receptor agonists and antagonists would be usef......en the tapeworm secretes this signal molecule, the intestine closes off and nothing moves. That suggested to us that the intestine is not digesting material as it normally would." The cyclic GMP compound, Oaks adds, is cheap and e...Too much fibre can aggrevate cancer
...aid: "Colorectal adenomas are growths in the large intestine which are not cancerous, but some adenomas do eventually grow and turn into cancers. The recommendation remains that healthy diets should be high in vegetables, fruits and cereals." He added: "This trial has no clear implications for the development ...Celiac Disease in Type 1 Diabetes
...the absorption of food nutrients through the small intestine is impaired because of an allergic reaction to gluten. Both CD and diabetes are common chronic conditions in children. Previous studies have shown a connection between the two. Researchers examined 200 patients from the time they were diagnosed with...Caffeine reduces infant blood flow
...n artery supplying blood through most of the small intestine had a 22 percent decrease in BFV at one hour and a 32 percent decrease at two hours. Researchers also observed blood pressure, heart rate, and left ventricle output, but found no changes. Thus they conclude an initial dose of 20 milligrams of caffei...... gold standard for diagnosing CD remains the small intestine biopsy. Blood samples from 236 known diabetics (1-18 years in age) were tested for total IGA and IGA-EMA by immunofluorescence. Of the 17 that had positive blood tests, 12 were subsequently diagnosed with CD. This is a prevalence of about 5%, which...New Advances in Gastric Diagnostics: Smaller is Better
...n the capsule has been propelled through the small intestine system by normal peristalsis, the recorder is removed and the digital data downloaded into a computer for viewing. The Given capsulized system can provide images for the entire GI tract. It shows promise in diagnosing small bowel diseases including ...Appendicitis: Evolving Tools to Diagnose a Classic Disease
...ndition occurs when the appendix, a blind pouch of intestine at the proximal colon, becomes obstructed by mucus, stool, or lymphatic tissue. Infection ensues, which can rapidly evolve to perforation and sepsis. The risk of these complications, already elevated for children and those over 50, rises as appende...Non-Invasive Diagnostic Tests for Celiac Disease
...is an autoimmune inflammatory disease of the small intestine that is triggered in genetically susceptible persons by the ingestion of the gluten-containing grains wheat, rye, barley, and possibly oats. The condition is thought to result from the activation of both a T-cell and B-cell immune response, leading t...Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis
...red. Ulcerative Colitis generally affects thelarge intestine and Crohn’s Disease generally affects thesmall intestine. Ulcerative Colitis is the inflammation of the gut,which results in extensive ulceration of its inner surface withconsequential pain, loss of function and blood loss. Thedisease can requ......sulinotropic polypeptide (GIP), arereleased by the intestine throughout the day, and levels are increasedin response to a meal. These hormones are rapidly inactivated by theenzyme, DPP-4. The incretins are part of an endogenous system involvedin the physiologic regulation of glucose homeostasis. When bloodgluc...