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Interfering in Medical News

Neuronal survival and axonal regrowth obtained in vitro

... team led by Alain Privat has recently shown that an essential component interfering with regeneration was due to the activity of astrocytes, feeder cells that ... tissue. In order to do so, they used gene therapy based on use of interfering RNA. The short RNA sequences, which were made to measure, were inserted ...

Galil Medical Ltd. Sues HealthTronics for Interfering with the Galil/Endocare Merger Agreement

... Chancery Court, asking the Court to enjoin HealthTronics from further interfering with a merger agreement between Galil and Endocare, Inc., and to order ... this suit in an effort to stop HealthTronics from further tortuously interfering with Galil's merger with Endocare. He stated: "Galil looks forward to ...

Olivier Voinnet awarded 2009 EMBO Gold Medal

... this defense. "We did not know anything about the microRNAs or small interfering RNAs at that time," says the biologist. "Yet, with David, we managed to ... is, antiviral defense." Following the discovery of microRNA and short interfering RNA in a wide range of different organisms, one key question that has kept ...

Scientists Capture HIV Transfer Among T-Cells on Video

... Team suggests there are many targets now for interfering with the process FRIDAY, March 27 (HealthDay News) -- The ... of virus between T-cells. This suggests there are many targets for interfering with the process," Chen said. To capture the transfer of HIV from ...

CSHL scientists correlate enzyme expression levels with chemotherapy drug response

... complex, multi-step process by which cells divide and multiply. By interfering with topoisomerases in cancer cells, doxorubicin and other drugs in the ... of so-called short-hairpin RNAs (shRNAs), each of which is capable of interfering with the expression of a specific gene or genes. "In these ...

Sperm Cell Insights May Aid Stem Cell Research

... in the genetically altered flies regained stem cells, compared with 97 percent of testis in normal flies. "We know now that in the fly testis, interfering with Jak-STAT signaling interferes with the process of dedifferentiation," Erika Matunis, an associate professor of cell biology, said in a ...

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Interfering in Medical Technology

DNA Therapeutics Closes 2.2 Million EUR Series A Financing Round

... damages caused by these therapies. The innovative aspect of siDNA (signal interfering DNA) technology developed in DNA Therapeutics is to use a short fragment ... was founded in June 2006. Its original siDNA technology consists in interfering with DNA repair pathways that cancer cells use to resist radiotherapy and ...

National Cancer Institute Research Identifies Unique Mechanism of Brostallicin's Anti-Tumor Effectiveness

... as well as with newer targeted therapies, in preclinical experimental tumor models. Brostallicin binds covalently to DNA within the DNA minor groove, interfering with DNA division and leading to tumor cell death. More than 200 patients have been treated with brostallicin in single-agent and combination ....

Prometheus Announces New Findings Regarding Patients at Risk for Celiac Disease at DDW

... Celiac Celiac disease is an immune-mediated digestive disease that is triggered by the consumption of gluten and damages the small intestine, interfering with the absorption of nutrients from food. Gluten is a protein found in grains such as wheat, barley and rye. Symptoms of celiac disease will vary ...

Raptor Pharmaceuticals Receives Notices of Allowance for Two NeuroTrans(TM) Patent Applications

... endothelial membrane in the BBB. NeuroTrans(TM) has also been conjugated to a variety of protein drugs, including enzymes and growth factors, without interfering with their therapeutic functions. About Raptor Pharmaceuticals Corp. Raptor Pharmaceuticals Corp. ("Raptor") is dedicated to speeding ...

NanoVibronix Receives Wound Healing Indications in Europe for its PainShield(TM) Device

... properties. NanoVibronix has created a platform that allows physicians to easily apply therapeutic ultrasound to assist in wound healing without interfering with any of the other modalities that are being utilized. Our simple-to-use, portable patch-based device can treat wounds in the hospital or at ...

Genes Identified That Enhance Tumor Cell Sensitivity to CTI's Cancer Drug Brostallicin

... as well as with newer targeted therapies in preclinical experimental tumor models. Brostallicin binds covalently to DNA within the DNA minor groove, interfering with DNA division and leading to tumor cell death. More than 200 patients have been treated with brostallicin in single-agent and combination ....

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Interfering in Medical Products

Pediatric ThermoWrap™

Description:... The Pediatric ThermoWrap™ is designed to fit the proportions of your young patient and wraps around the entire body, without interfering with the sterilized area of ....
Company:MTRE Advanced Technologies Ltd.

Gentamicin Sulfate: Liquid

Description:... Gentamycin sulfate is effective against gram positive and gram negative bacteria, as well as mycoplasma, by interfering with bacterial protein synthesis by binding to the 30S subunit of ribosomes. Its suggested working concentration of 50 mg/L is generally non-toxic to ...
Company:CellGro by Mediatech

Gentamycin Sulfate: Powder

Description:... Gentamycin sulfate is effective against gram positive and gram negative bacteria, as well as mycoplasma, by interfering with bacterial protein synthesis by binding to the 30S subunit of ribosomes. Its suggested working concentration of 50 mg/L is generally non-toxic to ...
Company:CellGro by Mediatech

BD Visitec Speculums

Description:... Open wire loops decrease the chance of interfering with instruments, Designed to retract the eyelid during ophthalmic microsurgery or minor office ...
Company:BD Ophthalmics

HDL-C Immuno FS

Description:... Specific immunochemical inhibition of non-HDL-lipoproteins. Excellent correlation with established reference methods. Endpoint assay. Unaffected by interfering substances. Liquid stable, ready-to-use reagent. Available with calibrator: Trucal HDL/LDL and control: Trulab ....
Company:DiaSys Corporation

LDL-C Select FS

Description:... reagent. Selective direct single measurement. Only one measurement. Excellent correlation with established reference methods. Unaffected by interfering substances. Available with Calibrator: Trucal HDL/LDL and control: TruLab ....
Company:DiaSys Corporation

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Interfering in Medical Definition

Cryostasis (clathrate hydrates)

... as the cells shrink, the solutes inside the cells are concentrated in the remaining water, increasing the intracellular ionic strength and interfering with the organization of the proteins and other organized intercellular structures. Eventually, the solute concentration inside the cells reaches the ...
Interfering in Medical Dictionary

Blurred vision

... is a gradual clouding of your eye 's lens , marked by blurred vision , impaired night vision , and halos around lights. If these problems start interfering with your life, discuss cataract surgery with your opthalmologist. Excessively high doses of stimulants such as amphetamine s result in ...

Chemotherapy

... sick, vomiting and a lowering of immunity . People's sex lives can also be affected. Chemotherapy is a drug treatment that works by interfering with the cancer cell 's ability to grow or reproduce. Different groups of drugs work in different ways to fight cancer cells and shrink tumor ....

Contraception

... to treat wounds , as well as kidney and lung problems. Contraception Definition Contraception ( birth control ) prevents pregnancy by interfering with the normal process of ovulation , fertilization , and implantation. There are different kinds of birth control that act at different points ...

Croup

... ... Croup This general term refers to the inflammation and narrowing of the upper parts of the air passages that lead into the lungs , interfering with breathing . Croup is an infection of the tissue s around the vocal cords in young children. It causes a characteristic barking cough . ...

Ileum

... absorbed in the terminal ileum , a part of the small intestine often affected by Crohn's disease . If inflammation of your terminal ileum is interfering with your ability to absorb this vitamin , you may need monthly B-12 shots for life. The small intestine has 3 parts: the duodenum , the ...

Injury

... process. This scar tissue may lead to a compress ion of the nerve s and blood vessels. An injury to the spinal cord can cause ED by interfering with nerve signals. Treatment s for prostate cancer , including radiation and prostate removal , can damage the nerve s that control erections. ...

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Interfering in Biological News

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

... Laboratory studies suggest that a single small interfering RNA could reduce production of the damaging ... from one of a set of four additional small interfering RNAs. Phillip D. Zamore, an HHMI investigator ... to turn off. These strands of RNA, known as short interfering RNA (siRNA), slice apart the original RNA, which ...

An easy way to find a needle in a haystack by removing the haystack

... to alter the matrices with which the samples were applied so that no more interfering matrix-related ions were generated. In other words: they tried to remove ... conditions for rational selection of matrices that did not generate interfering ions but provided rich mass spectra of particular kinds of metabolites in ...

New lead on malaria treatment

... antibiotic fumagillin can stop malaria parasites from growing, possibly by interfering with MetAP2. But the man-made version of fumagillin causes brain cells to ... to fumagillin in hopes of finding one less toxic but still effective in interfering with PfMetAP2. They chose to further study one of these compounds, ...

Small molecules might block mutant protein production in Huntington's disease

... May 3 in Nature Biotechnology. The researchers' approach relies on interfering with the steps by which genetic information in cells is "translated" from ... proteins. The researchers also designed short lengths of RNA called small interfering RNA, or siRNA, to interfere with CAG repeats. In cells from ...

UNC study: Tinkering with the circadian clock can suppress cancer growth

... the American Academy of Arts and Sciences. "Our study indicates that interfering with the function of these clock genes in cancer tissue may be an ... their lives by 50 percent. The researchers then wanted to know how interfering with the cryptochrome gene had reduced the incidence of cancer. By closely ...

Researchers solve piece of large-scale gene silencing mystery

... survival. But Pikaard and his collaborators' research suggests that small interfering RNAs (siRNAs) can direct silencing agendas that are much more ... RNAi to a "search and destroy mission." Fragments of RNA known as small interfering RNAs (siRNAs) prevent specific genes from being expressed by guiding ...

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Interfering in Biological Technology

Sirnaomics Receives SBIR Grant from NIH/NCI for Its Multi-Targeted Lung Cancer siRNA Therapeutics

... represent a unique approach for truly realizing the advantages of small interfering RNA (siRNA)-based drugs to treat various critical human diseases. ... role in molecular biology by silencing genes through chromatin remodeling, interfering with protein synthesis, and in its best-studied mode of action quashing ...

Sirnaomics Receives SBIR Grant from NCI For Its Multi-Targeted Cancer siRNA Therapeutics

... represent a unique approach for truly realizing the advantages of small interfering RNA (siRNA)-based drugs to treat various critical human diseases. ... role in molecular biology by silencing genes through chromatin remodeling, interfering with protein synthesis, and in its best-studied mode of action quashing ...

Silence Therapeutics Receives Allowance from United States Patent and Trademark Office for its Core RNAi Patent

... 10/633,630, "Interfering RNA Molecules," which covers stabilized, small interfering RNA (siRNA) molecules with defined positional modifications. The claims ... for patent application No. 2003260370 entitled "Further novel forms of interfering RNA molecules." The European equivalent of the US and Australian patent ...

M. D. Anderson Automates Laboratory Workflow with Stone Bond Technologies : EE-LIMS™ from Stone Bond Technologies Will Document Activities within the Laboratory Workflow at the siRNA Facility, Increasing Throughput, While Reducing Risks

... The newly established Small interfering Ribonucleic Acid (siRNA) Facility at M. D. Anderson Cancer Center has been ... As one of the newest fields in the study of nucleic acids, small interfering RNA has shown considerable potential in laboratory studies to change how ...

Intradigm Licenses Key Next Generation RNA Interference (RNAi) Intellectual Property From University of Massachusetts Medical School

... in Emerging RNAi Industry through Addition of Important and Novel Small interfering RNA (siRNA) Structural IP PALO ALTO, Calif., April 9, 2008 /PRNewswire/ ... (IP) covering certain efficacy-enhancing structural elements of small interfering RNA (siRNA) from the University of Massachusetts Medical School. The ...

Sirnaomics Received Multiple Government Fundings For Its Multi-Targeted siRNA Therapeutics Programs

... represent the unique approach for truly realizing advantages of small interfering RNA (siRNA)-based drugs, to treat various critical human diseases. ... role in molecular biology by silencing genes through chromatin remodeling, interfering with protein synthesis, and in its best-studied mode of action quashing ...

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Interfering in Biological Products

ProteoExtract Protein Precipitation Kit from Calbiochem

Description:... purification procedure that can both concentrate the proteins and remove interfering substances in one step. • The ProteoExtract™ Protein ... of sources. Detergents, chaotropes buffer reagents, salts and other interfering compounds stay in solution. Precipitated proteins can easily be ...
Company:Calbiochem

Anti-Sheep/Goat Sac-Cel - Solid-phase Separation System from IDS Ltd

Description:... stages, but delivering firmer pellets in much shortened centrifugation time. After incubation with primary antibody (in the absence of potentially interfering carrier serum) and tracer, Sac-Cel is added. Following a second incubation, the reaction volume is increased by dilution prior to a short, low speed ...
Company:IDS Ltd

Custom siRNA Synthesis from Thermo Scientific

Description:... Thermo has recently launched a custom synthesis service for synthetic small interfering RNA (siRNA). Thermos siRNA molecules are: Composed of 18-20 RNA bases with 2 DNA bases overhang at the 3-terminus PAGE purified Delivered fully ...
Company:Thermo Scientific

ShortCut RNase III from New England Biolabs

Description:... ShortCut RNase III, used with its manganese-containing reaction buffer, converts long double-stranded RNA into a heterogeneous mix of short (1825 bp) interfering RNAs (siRNA) suitable for RNA interference in mammalian cells. 1.3 units (1 l) of ShortCut RNase III is sufficient to convert 1 g of dsRNA into siRNA ...
Company:New England Biolabs

TransIT-siQUEST Transfection Reagent from Mirus Bio Corporation

Description:... sequence-specific inhibition of target mRNA can be realized without introducing an interferon response. These short dsRNA, referred to as small interfering RNAs (siRNA), act catalytically at sub-molar ratios to cleave greater than 95% of the target mRNA in the cell. The RNA interference effect can be ...
Company:Mirus Bio Corporation

TransIT-siQUEST Transfection Reagent from Mirus Bio Corporation

Description:... sequence-specific inhibition of target mRNA can be realized without introducing an interferon response. These short dsRNA, referred to as small interfering RNAs (siRNA), act catalytically at sub-molar ratios to cleave greater than 95% of the target mRNA in the cell. The RNA interference effect can be ...
Company:Mirus Bio Corporation

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Interfering in Biological Definition

Defective interfering particle

... Defective interfering particles ( DIPs ) are virus particles that are missing part or all of their genome . Because of these deletions in their genome, DIPs cannot ...

Gene

... RNA molecules are actually the functional end products. For example, RNAs known as ribozymes are capable of enzymatic function , or small interfering RNAs have a regulatory role. The DNA sequences from which such RNAs are transcribed are known as non-coding RNA , or RNA genes . All living ...

HeLa

... signal transduction . HeLa cells have proven difficult to control. They sometimes contaminate other cell cultures growing in the same laboratory, interfering with biological research. The degree of contamination is unknown, because few researchers test the identity or purity of already-established cell ...
Interfering in Biological Dictionary

SiRNA

... Small interfering RNA ( siRNA ), sometimes known as short interfering RNA or silencing RNA, is a class of ... small RNA molecules – microRNA (miRNA) and small interfering RNA ( siRNA ) – are ... At some point ...

Small nuclear RNA

... Genes: a Model System to Study Fundamental Mechanisms of ... Small interfering RNA Mediating RNA interference in cultured mammalian cells. ... ... and determine their. individual functions. ... ... (miRNA), small interfering RNA (siRNA), and small nuclear RNA (snRNA), from tissues and ....

Spirochetes

... from the midgut of ticks; organisms reacted with ... Spirochetes are shaped like long coils and travel with a wave-like motion. ... model that interfering with the spirochete's motility in this way prevented it ... Spirochetes disease information including symptoms, diagnosis, misdiagnosis, ...

RNAi

... living cells that helps to control which genes are active and how active they are. Two types of small RNA molecules – microRNA (miRNA) and small interfering RNA (siRNA) – are ... RNAi .net - News, posters, events and suppliers from the main portal site for the field of RNAi research. ... ...

RNA interference

... living cells that helps to control which genes are active and how active they are. Two types of small RNA molecules – microRNA (miRNA) and small interfering RNA (siRNA) – are ... RNA interference ( ¦är¦en¦ā ′intər′firəns ) ( cell and molecular biology ) The process by which foreign, ...

Gene silencing

... living cells that helps to control which genes are active and how active they are. Two types of small RNA molecules – microRNA (miRNA) and small interfering RNA (siRNA) – are ... Today, gene silencing —or RNA interference (RNAi), as it is now known—has ... It turns out that gene ...

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(Date:12/25/2014)... Dec. 25, 2014 (HealthDay News) -- Overeating is common during ... eat in moderation, an expert says. "Don,t arrive at ... calories if you know you,ll be attending a party, but ... Ashbey-Pejoves, lead dietitian at Northern Westchester Hospital in Mount Kisco, ... to eat healthy during the day and even to have ...
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