Single stem cells from bone heal a broken heart
Myocardial infarction results in irreversible damage to the heart that c...adult human stem cell transplantation. Myocardial infarction and heart failure are associated with major morbidity and mortality and there are currently limited ...Mouse gene shows new mechanism behind cardiac infarction in man
...more common in people who had a history of cardiac infarction than those without. “This is an example of how an unbiased genetic strategy based on a mice model can teach us more about common human diseases,?says researcher Jacob Lagercrantz of the Gustav V research institute, Karolinska Institutet. The gene c...Morphine for Chest Pain Increases Death Risk
... patients with non-ST-segment elevation myocardial infarction (non-STEMI), a categorization of heart attack based on electrocardiogram (ECG) readings. These patients typically arrive at emergency rooms with chest pain, but often will not have telltale signs of a heart attack on the initial ECG. They might be di...Survival of heart patients on beta-blockers varies greatly with genetic variation
...ar says. "Data from patients with acute myocardial infarction have shown that beta-blockers are generally effective. They are known to decrease the size of the infarct and seem to prolong survival, on average." Recent research, however, reveals that variations in the beta-adrenergic receptor genes affect the b...Bone marrow stem cells may heal hearts even years after heart attacks
... large amount of patients with previous myocardial infarction and non-treatable complaints," said Bodo E. Straue...in global left ventricular function by 15 percent, infarction wall movement velocity rose 57 percent, and there was a significant reduction of infarct size by 30 ...Caspase-3 Activation - An Indicator of Apoptosis in Image-Based Assays
...ar damage in diseases such as stroke or myocardial infarction (reviewed by Lavrik et al . 2005). Although the precise role in the initiation and progression of apoptosis is not known for all caspases, their involvement as an indicator alone and as a potential leverage point for drug treatment make them widely ...Coronary heart disease bids Adieu
... fortified with folic acid could reduce myocardial infarction by 13% in men and 8% in women, with comparable reductions in death from CHD. "Using our most conservative assumptions, the estimated reductions in annual CHD mortality rates were 1% to 3%," the researchers report. In addition to consuming fortified ...Women find difficulty in calling it 'Quits'
...ho smoked had almost double the risk of myocardial infarction than did men. The increased risks of heart attack and stroke due to smoking are further exacerbated in women who also use oral contraceptives. Some studies have also pointed to the conclusion that women also may have nearly double the risk of lung ca...... protective against stroke than against myocardial infarction – resulting in an overall cardiovascular benefit similar to that of old classes of antihypertensive drugs. The authors concluded that, although calcium-channel blockers were effective in stroke prevention, they did not find that converting-enzyme inh...Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
...ble angina are now given a diagnosis of myocardial infarction without ST-segment elevation based on their cardiac troponin levels. Troponin levels additionally aid in risk stratification. The development of accelerated protocols for diagnosing ACS in patients with chest pain necessitates the reduction of turna...New Point-of-Care Methods to Measure Coronary and Cerebrovascular Risk
...st quintile had almost a 4-fold risk of myocardial infarction and stroke. This risk was similar even when statistical analysis controlled for the vascular risk factors mentioned above. In a complementary study, Raitakari and coworkers (JAMA. 2003;290:2277-228) followed adolescents 12-18 years old and found th...Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
...ontinuations were due to cardiac events(myocardial infarction in one patient and arrhythmia, diminishedcardiac output, and hypotension in the other patient). The incidence of hypomagnesemia (both overall and severe [NCICTC Grades 3 & 4]) was increased in patients receiving ERBITUXalone or in combination wi...Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
... vessel revascularization (TVR) in acutemyocardial infarction patients after two years. At two years, the cu...incidence of death,MI, and TVR in acute myocardial infarction patients. The resultsfrom MULTI-STRATEGY are anticipated to be presented at a prominentscientific sy......fibrillationand secondary prevention of myocardial infarction and stroke.Factor Xa is a validated target (one fo...illation and forsecondary prevention of myocardial infarction (MI) and stroke.Portola's second compound, PRT060128, is an oral and intravenousADP receptor antagon...