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Induction in Medical News

New Report Just Published: World Multiple Myeloma Therapeutics Market Report

... is also analyzed by the Lines of Treatment -- induction Therapy for SCT Candidates, induction Therapy for Non-SCT Candidates, and Therapy for ... II-28 Initial Treatment Regimen II-28 induction Therapy for SCT Candidates II-28 ...

U-M study finds voice box can be preserved, even with the largest cancers

... Study participants were given one round of induction chemotherapy, an initial dose designed to see if ... Those whose tumors did not respond to the induction chemotherapy were referred for surgery. ... two studies. Eighty-one percent responded to the induction chemotherapy and many saw their tumors shrink ...

Anadys Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results and Highlights

... studies in animals that demonstrated stable induction of interferon-dependent pathways at doses that ... serious adverse events were reported. Biomarker induction indicative of immune activation was seen in a ... 800 mg and 1200 mg dose levels, minimal immune induction and no significant viral load decrease was noted. ...

St. Jude finds more than 100 gene variations linked with response to leukemia treatment

... of leukemic cells that survive after remission induction therapythe initial treatment. This measurement ... less-toxic treatment; and also shows if remission induction therapy will likely fail. The researchers ... and an increased risk of high MRD at the end of induction therapy. "Our finding that IL15 plays such an ...

Biopure Submits IND Application for Proposed Clinical Trial in Patients with Acute Myeloid Leukemia

... treatment of life-threatening anemia secondary to induction chemotherapy in patients with acute myeloid ... are unable to undergo potentially life-saving induction chemotherapy because of the profound anemia the ... 100% mortality within several months without induction chemotherapy. Biopure Corporation ...

Novel treatments show improvements in survival and response rates for leukemia and lymphoma

... fever, and mucositis. Dexamethasone in induction Can Eliminate One-Third of All Relapses in ... study found that the use of dexamethasone in the induction phase of combination chemotherapy led to a ... dexamethasone, rather than prednisone, as part of induction therapy. Following a pre-phase treatment ...

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Induction in Medical Technology

Cephalon Provides Clinical Update on Lestaurtinib in Relapsed Acute Myelogenous Leukemia

... population when given in sequence with standard induction chemotherapy compared to those treated with standard induction chemotherapy alone. An analysis of the study ... overall survival, compared to those who received induction chemotherapy alone. "We are disappointed ...

Induction Chemotherapy Followed by ChemoRadiotherapy Increased Time-to-Treatment Failure Compared to ChemoRadiotherapy Alone in Patients With Unresectable Locally Advanced Head & Neck Cancer

... - Phase 3 study has demonstrated that induction Chemotherapy prior to ChemoRadiotherapy ... Cooperative Group (TTCC) announced today that induction Chemotherapy (IC) delivered prior to standard ... and throat. "This trial showed that adding induction Chemotherapy to ChemoRadiotherapy increased ...

St. Jude Finds More Than 100 Gene Variations Linked With Response to Leukemia Treatment

... of leukemic cells that survive after remission induction therapy -- the initial treatment. This ... less-toxic treatment, and also shows if remission induction therapy will likely fail. The researchers ... and an increased risk of high MRD at the end of induction therapy. "Our finding that IL15 plays such ...

Dacogen(R) (decitabine for injection) Data Presented on a Phase II Clinical Trial in Elderly Patients with Acute Myeloid Leukemia (AML)

... are typically considered ineligible for standard induction chemotherapy. These data were presented today at ... cannot endure the toxic side effects of standard induction chemotherapy," said lead investigator, Amanda ... to minimize the risk of the disease progression. induction chemotherapy, the standard front-line AML ...

Zevalin Consolidation in Patients With Complete Remission After Induction Therapy Results in Durable Remission of More Than 67 Months

... that achieved a complete remission (CR) after induction therapy has not yet been reached with an ... 409 patients who achieved a CR/CRu or PR after induction therapy. Patients that achieved a CR after induction therapy achieved a median PFS of >67 months ...

Sunesis Pharmaceuticals Announces Presentation of Voreloxin Clinical Data in Patients with Acute Myeloid Leukemia at the 50th Annual Meeting of the American Society of Hematology

... who are unlikely to benefit from standard induction chemotherapy. Many older AML patients cannot tolerate or do not respond well to standard induction chemotherapy. In Schedule A, 29 patients with a ... 17 percent, which compares favorably to standard induction chemotherapy. Infection was the most common ...

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Induction in Medical Products

Aestiva/5 Induction

Description:... Aestiva Excellence for the induction Room. The Aestiva/5 induction offers innovative versatility for the induction Room. The ...
Company:Datex-Ohmeda, Inc.

Direct Image Flat SSV®

Description:... The Chalam Flat is designed for routine vitrectomy, optic nerve neurotomy and induction of posterior vitreous detachments. It is also useful for macula whole surgery, epiretinal membranes and for removal of tractional epiretinal ...
Company:Volk Optical, Inc.

Direct Image Flat

Description:... The Flat is designed for routine vitrectomy, optic nerve neurotomy and induction of posterior vitreous detachments. It is also useful for macular hole surgery, epiretinal membranes and for removal of tractional epiretinal ...
Company:Volk Optical, Inc.

Mars Enduro

Description:... Due to the motorised longitudinal adjustment and the filigreed construction, MARS Enduro provides optimum working conditions in examination, induction and operating theatre. Universal coupling points ensure that the table can be extended at any time with modular accessory ....
Company:TRUMPF Medical Systems, Inc.

Jupiter

Description:... and flexible in every situation. For many complicated surgery positions, the patient can already be positioned optimally on the JUPITER during the induction to the operating theatre. In the operating theatre, the high level of stability of JUPITER guarantees the same degree of safety as stationary ...
Company:TRUMPF Medical Systems, Inc.

Cardiocap/5

Description:... all-in-one anesthesia monitor. The Cardiocap/5 is a compact, all-in-one monitor designed for use in the operating room, ambulatory surgery unit, induction room and PACU. The Cardiocap/5 offers full vital signs monitoring capabilities from the monitoring of oxygenation and circulation to advanced airway ...
Company:Datex-Ohmeda, Inc.

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Induction in Medical Definition

Anterior mediastinal mass

... requires addition of cisplatin-based chemotherapy in addition to those in stage II and III. For those with invasive thymoma, treatment is based on induction chemotherapy, surgical resection, and post-surgical radiation. 5-year survival for invasive thymoma is between 12-54% regardless of any myasthenia ...

Artificial induction of immunity

... variolation and smallpox . Typical site of inoculation in Europe and the British colonies The earliest recorded artificial induction of immunity in humans was by variolation or inoculation , which is the controlled infection of a less lethal natural form of smallpox (known as ...

Depolarization-induced suppression of inhibition

... of specific interneuron types. J Neurosci. Jul 20;25(29):6845-56. Carlson G, Wang Y, Alger BE. (2002) Endocannabinoids facilitate the induction of LTP in the hippocampus. Nat Neurosci. Aug;5(8):723-4. Cristino L, de Petrocellis L, Pryce G, Baker D, Guglielmotti V, Di Marzo V. (2006) ...

Proteopathy

... MP, Jucker M (2006). "Inducible proteopathies". TINS 29 : 438-443. PMID 16806508 . ^ Meyer-Luehmann M, et al. (2006). "Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host". Science 313 : 1781-1784. PMID 16990547 . ...

Thymocyte

... called "death by neglect") those T cells which would be non-functional due to an inability to bind MHC. Negative selection is the active induction of apoptosis in thymocytes with a high affinity for self peptides or MHC. This eliminates cells which would direct immune responses towards ...

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Induction in Medical Dictionary

Ovulation

... or referral to a physician may be necessary because ovulation induction is often suggested. For example, if ovulation is a problem then ... endometriosis or to remove fibroid s from the womb. Indication: for induction of ovulation and pregnancy in anovulatory infertile patients with ...

Remission

... rates of greater than 95% have been achieved in children. Remission induction therapy. The purpose of the first phase of treatment is to kill the leukemia cells in your blood and bone marrow . Remission induction therapy: This is the first phase of treatment . Its purpose is to kill ...

Adenoma

... or adenoma tous hyperplasia and the client desires a pregnancy , consultation or referral to a physician may be necessary because ovulation induction is often suggested. Liver tumor s ( adenoma s) Low blood sugar ( hypoglycemia ) High blood uric acid (a risk factor for gout ) High ...

Androgen

... over the top and front of the head and by the healthy condition of the scalp. ACOG Supports Use of Misoprostol for Medical Abortion and Labor induction (November 30) Ob-Gyns Seeing More Patients Per Week (October 31) Androgen Replacement No Panacea for Women's Libido (October 31) ACOG Writes FDA ...

Beta

... . Mfg: Novoste Corporation. The Wnt/ beta -catenin signal transduction pathway plays a critical role in axis formation and head versus trunk induction during early vertebrate embryogenesis. - A lack of beta -carotene (pro- vitamin A ), vitamin E , and B complex in lung tissue may be related ...

Collapsed lung

... blood to body organ s heart disease , and abnormalities in any of the heart valves adjustment to a high altitude ... It has the fastest induction and recovery and is the safest because it does not slow breathing or blood flow to the brain. However, it diffuses rapidly into air-containing ...

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Induction in Biological News

REGiMMUNE presents enhanced efficacy data in preclinical transplantation models

... enhanced efficacy in transplantation tolerance induction in models of skin transplantation and acute ... in a poster titled "Donor-Specific Tolerance induction by a Liposomal Formulation of KRN7000 (RGI-2001) ... with Sirolimus in transplantation tolerance induction in mouse models. Study Results ...

Lab-on-a-chip homes in on how cancer cells break free

... is triggered. We refer to this phenomenon as the induction time of the cell," Wildt says. "After this induction time, the cell then snaps back and contracts. We ... The researchers have speculated that the induction time for cancer cells, as compared to ...

Scripps research scientists identify blood component that turns bacteria virulent

... have identified an essential component for the induction of virulence gene expression in response to host ... uptake inside the cell greatly decreased, induction of toxin gene expression did not occur, and ... CO2 activity is not essential to virulence factor induction and that bicarbonate, not CO2, is the signal ...

National Inventors Hall of Fame welcomes 2008 inductees

... information about the 2008 inductees who will be recognized over the induction weekend can be found at the Hall of Fames web site, ... 2002 Nobel Prize in Physics. Inventors may be nominated by anyone for induction into the Hall of Fame, but they must hold a U.S. patent to be considered. ...

Natural compound in broccoli could treat devastating genetic skin disorder

... In EBS patients, skin blisters heal without scarring, correlating with an induction in the expression of the protein K6, to which K5 is related, and of K17 ... found that exposing keratinocytes to sulforaphane caused the selective induction of keratins 16 and 17. Moving to an EBS mouse model with a K14 deficiency, ...

Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients

... is a two-hour infusion administered every 8 weeks, following a standard induction regimen that requires treatment at weeks 0, 2 and 6. As a result, REMICADE ... is a two-hour infusion administered every 6 weeks, following a standard induction regimen that requires treatment at weeks 0, 2 and 6. ...

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Induction in Biological Technology

Celsis Outlines the Top Five Advantages of Cryo-plateable Hepatocytes

... of freshly isolated hepatocytes for studies like induction severely restrict the researcher's choices for ... and accelerating time to market. Standard induction studies, as an example, typically may be ... activities, genotypes and for applications like induction or transport, representing another major ...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

... shows an extended duration of response in an induction and maintenance clinical trial of Crohn's disease ... at week 6. The trial demonstrated that after the induction period 62 percent of patients achieved response ... rance to infliximab. It consists of an open-label induction phase (400 mg of Cimzia(R) sub-cutaneously at ...

ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week

... trial results from more than 430 patients in the induction phase of the PROTECT-1 study in the following ... The innovative trial design includes a 12-week induction phase, during which patients with ... to induce a clinical response or remission. The induction phase of the study is followed by a four-week, ...

Tigris Pharmaceuticals Presents Results of Breast Cancer Research at AACR Annual Meeting

... histone deacetylase inhibitor, followed by CYP1A1 induction and subsequent AFP metabolism into active species ... sequence on the CYP1A1 promoter region, causing induction of CYP1A1 transcription. This enzyme expression ... DNA. This results in phosphorylation of p53 with induction of the p53 downstream target p21Waf1/Cip1 and ...

Vion Pharmaceuticals Submits New Drug Application for Onrigin(TM)

... Injection as a single agent for remission induction treatment for patients sixty years of age or ... a lower rate of response to currently available induction chemotherapy and shorter overall survival due, in ... age and poor performance status tolerate current induction treatments poorly. A 2005 study by Lang et al, ...

Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin

... AML patients unlikely to benefit from standard induction chemotherapy. Interim results recently presented ... 17 percent, which compares favorably to standard induction chemotherapy. Data on the median duration of ... are not considered candidates for standard induction therapy or decline therapy, resulting in an acute ...

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Induction in Biological Products

GenoStat Inducible Expression System from Upstate

Description:... GenoStat Ligand in the tissue culture media. The GenoStat Inducible Expression System provides maximal levels of gene expression (often reaching fold induction levels greater than 10,000), while minimizing basal expression levels in the absence of ligand. This precise control of gene expression utilizing the ...
Company:Upstate

Human Neural Stem Cell Functional Identification Kit from R&D Systems

Description:... Kit contains specially formulated media supplements, which can be used for the short-term maintenance, differentiation, and expansion of NSCs and the induction of NSCs into astrocyte, neuron and oligodendrocyte lineages. An antibody panel consisting of mouse anti-human Nestin, mouse anti-human Glial ...
Company:R&D Systems

Curcumin (technical grade) from Cayman Chemical

Description:... Curcumin is an extract of turmeric root with antioxidant, anti-tumor promoter, and anti-inflammatory properties. Curcumin inhibits the induction of NOS in ....
Company:Cayman Chemical

CopyControl cDNA, Gene and PCR Cloning Kit w/ Chemically Competent E. coli cells from EPICENTRE Biotechnologies

Description:... (white) colonies and yield > 5 X 105 cfu/µg of PCR product. Kits include chemical competent TransforMax™ EPI300™ E. coli required for induction of clones to multiple copy ....
Company:EPICENTRE Biotechnologies

GeneSwitch-CHO Cell Line from Invitrogen

Description:... The GeneSwitch Cell Lines stably express the regulatory GeneSwitch protein from pSwitch. Each cell line is functionally tested for induction ability by transient transfection with the expression control vector pGene/V5-His/lacZ and by assaying for Beta-galactosidase expression after ...
Company:Invitrogen

TargeTron Gene Knockout System from Sigma-Aldrich

Description:... primer sets to mutate the TargeTron intron template via PCR, ligation of the fragment into the pACD4K-C linear vector, transformation of the host, induction of gene disruption, selection by kanamycin resistance (insertion of activated marker) and screening for the desired knockout. Gene knockout using ...
Company:Sigma-Aldrich

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Induction in Biological Definition

Barbiturate

... 3 Other non-therapeutical use 4 References Medical uses Today barbiturates come are mainly used as anticonvulsants and for the induction of anesthesia . These barbiturates are available in the U.S.: Amobarbital (Sodium Amytal; hypnotic) Aprobarbital (hypnotic) ...

Developmental biology

... , embryology , endoderm , extra-embryonic membrane , fetus (or foetus ), gastrula , gastrulation , germ layer , germ plasm , germination , induction , juvenile , larva , maternal effect , mesoderm , metamorphosis , morphogenesis , morula , neoteny , neural development , nymph , ontogeny ...

Hormone

... secretion and the signal transduction of the receiving tissue. Hormone actions vary widely, but can include stimulation or inhibition of growth, induction or suppression of apoptosis (programmed cell death), activation or inhibition of the immune system , regulating metabolism and preparation for a ...

Long-term potentiation

... Acad Sci U S A 94 (9), 4761-5. PMID 9114065 ^ Malinow R, Schulman H, Tsien RW (1989) "Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP". Science 245 (4920), 862-6. PMID 2549638 ^ Otmakhova NA, Otmakhov N, Mortenson LH, Lisman JE (2000) ...

Molecular genetics

... such as yeast and mice , it is possible to induce the deletion of a particular gene, creating a gene knockout . Alternatives include the random induction of DNA deletions and subsequent selection for deletions in a gene of interest, the application of RNA interference and the creation of transgenic ...

Zona pellucida

... ZP3 , is responsible for sperm binding, adhering to proteins on the sperm plasma membrane. There is evidence that ZP3 is then involved in the induction of the acrosome reaction, whereby a spermatozoon releases the contents of the acrosomal vesicle . Reference Oehninger S. 2003. Biochemical ...

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Induction in Biological Dictionary

Spirochetes

... on ... hindered the study of this spirochete's genetics and. physiology. ... reconverted to spirochetes in relation to their age and type of induction treatment. ... against the mobile spirochetes was >128 microg/ml at 37 degrees C in ... Keynote Address - The Complexity of Vector-borne ...

SiRNA

...... siRNA technology is now extensively recognized as a powerful tool for the ... Describes the design of small interfering RNA ( siRNA ) for the induction of RNA interference (RNAi) in a variety of organisms. siRNA Synthesis. Premium quality siRNAs ... Made-to-order Silencer Select siRNA ...

Relaxed DNA

... buffer ... Relaxation of DNA -loops was analysed by the method of anomalous viscosity time ... The dose-responses for DNA -loop relaxation , induction of at least one residual ... All topoisomerases can relax supercoiled DNA , and DNA gyrase, present in ... the inter-conversion of relaxed ...

Morphogenesis

... is essential for development of ... Mammary gland morphogenesis and. differentiation occur during postnatal development. ... The induction of the lung also involves the interplay between FGFs and Shh. ... The control of branching morphogenesis involves determining when and where a ......

Mesoderm

... set of techniques, paradigms, and models necessary for a student to understand the core of developmental biology ... MESODERM INDUCTION. induction AND SIGNALING MOLECULES ... Once inducted, mesoderm then differentiates into its many derivatives. ... The epiblast keeps moving and forms a ...

Macromere

... ... likely through direct contact with macromere progeny, or at most a ... For macromere progeny to be competent to receive the micromere induction signal, ... Developmental Biology provides the fundamental set of techniques, paradigms, and models necessary for a student ... cleavage, each ...

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