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Immunoglobulin in Medical News

MEDEX Global Group Cautions: Beware of Rabies When Abroad

... of rabies vaccines and the human or equine rabies immunoglobulin (RIG) recommended by the World Health ... exists in the countries where the vaccine and immunoglobulin are most needed," according to Dr. Henry ... they will not need the expensive and scarce immunoglobulin (RIG) if they are bitten by an animal in a rabies ...

NYU School of Medicine pathology researchers solve another mystery in B lymphocyte development

... Immunology ahead of the June 2009 print issue has found that homologous immunoglobulin (lg) alleles pair up in the nucleus at stages that coincide with V(D)J ... and ATM Coordinate Monoallelic Recombination and Nuclear Positioning of immunoglobulin Loci," researchers found that RAG-mediated cleavage occurs on one allele ...

Scott Miller and Company Premieres "A CALL TO ARMS 2009 EDITION" at the Camelot Theaters in Palm Springs

... the anthrax vaccine, when the immune system creates Furin-sequestering immunoglobulin gamma (IgG) antibodies in response to the BioThrax™ anthrax ... damage due to the sequestering of the FURIN activator protein by the immunoglobulin gamma (IgG) antibody, which can be created as an immune response to ...

Studies Ignite Hope for Long-Acting Allergy Vaccines

... in the bloodstream. People with allergies produce an antibody called immunoglobulin E, which sets off a cascade of chemicals to fend off a perceived allergen, ... symptoms that people experience. Another antibody in blood, called immunoglobulin G, fights infection. "What the study showed was that the G antibodies ...

Immunoglobulin Can Predict Some Diabetic Complications

... excretion of IgM foretells serious cardiovascular issues: study FRIDAY, Aug. 7 (HealthDay News) -- Swedish researchers say that immunoglobulin M (IgM) is a reliable predictor of cardiovascular complications in people with type 1 diabetes who have diabetic nephropathy (DN) -- kidney damage ...

Bcl6 gene sculpts helper T cell to boost antibody production

... cell proliferation and antibody development. "In germinal centers, the B cells not only proliferate but they also undergo hypermutation in their immunoglobulin genes so they can produce a diverse class of antibodies," Dong said. "These mutations also allow production of antibodies with stronger affinity for ...

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Immunoglobulin in Medical Technology

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... antibody platform, used Sangamo's ZFNs to knock out the gene encoding rat immunoglobulin M (IgM), an important gene for rat antibody production. Inactivation of ... rats that exclusively express human antibodies encoded by transgenic human immunoglobulin genes. "Creating a knockout rat was the biggest challenge OMT faced," ...

Human Genome Sciences Reports Positive Data from Long-Term Treatment with LymphoStat-B(R) in Patients with Active Systemic Lupus Erythematosus

... that LymphoStat-B also promoted progressive normalization of autoantibody, immunoglobulin and complement levels over 2.5 years of therapy in SLE patients (Stohl et ... presentation reporting the progressive normalization of autoantibody, immunoglobulin and complement levels over 2.5 years of treatment with LymphoStat-B, click ...

Baxter and The Alzheimer's Disease Cooperative Study Group to Pursue a Phase III Study of Gammagard Liquid in Patients With Alzheimer's Disease

... Liquid [Immune Globulin Intravenous (Human)] (IGIV), an intravenous immunoglobulin preparation, for the treatment of patients with mild to moderate ... a broad spectrum of immunoglobulins (antibodies), and is indicated as an immunoglobulin replacement therapy in patients with primary immunodeficiency. GAMMAGARD ...

Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes

... injection, is a novel-engineered fusion protein, consisting of a dipeptidyl peptidase-IV (DDP-IV) protected GLP-1 analog linked to a fragment of immunoglobulin G4 that is believed to increase the duration of its pharmacological effect. Based on this study presented at this year's ADA meeting, LY2189265 is ...

Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy

... doses. About IgA Nephropathy IgA nephropathy is the most common primary cause of kidney disease and occurs as a result of the deposition of immunoglobulin A in the kidney. The injured kidney tissues secrete a variety of inflammatory mediators including CCL2. CCL2 in the tissue causes CCR2-expressing ...

Aerovance Initiates Phase IIb Clinical Trial with Aerovant(TM) for the Treatment of Uncontrolled Asthma

... as compared to placebo. Secondary endpoints include pulmonary function, time to exacerbation, daily peak expiratory flow (PEF) and symptom scores, immunoglobulin E (IgE) levels, and fractional concentration of expired nitric oxide (FeNO). "Regulatory clearance and initiation of AeroTrial are significant ...

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Immunoglobulin in Medical Products

Viroclear®

Description:... virus type I (anti-HTLV-I), antibody to hepatitis C virus (anti-HCV), immunoglobulin M and total antibodies to hepatitis B core antigen (anti-HBc IgM and ... antigen (HBsAg), antibody to hepatitis B surface antigen (anti-HBs), immunoglobulin M and total antibody to hepatitis A virus (anti-HAV IgM and anti-HAV ...
Company:Blackhawk BioSystems, Inc.

IgE - Rapid Test Kit

Description:... The InstaTest IgE test kit is an immunochromatographic in vitro assay for detection of elevated levels of immunoglobulin E in human serum or plasma. Elevated concentration of IgE is commonly associated with allergic pathologies. It may also be caused by autoimmune ...
Company:Bio-Quant, Inc.

Virotrol III

Description:... For use as a quality assurance reagent in assays detecting immunoglobulin M (IgM) antibodies to hepatitis B core antigen (anti-HBc IgM), IgM antibodies to hepatitis A virus (anti-HAV IgM), hepatitis B e antigen (HBeAg) and ...
Company:Blackhawk BioSystems, Inc.

IgE (Total) EIA Test Kit

Description:... For the quantitative determination of immunoglobulin E (IgE) concentration in human serum. Patients with atopic allergic diseases such as atopic asthma, atopic dermatitis, and hay fever have ...
Company:ALPCO Diagnostics

Thyrotropin-Binding Inhibitory Immunoglobulin (TBII)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

Immunofixation Electrophoresis, Immunoglobulin D & Immunoglobulin E, Serum

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories
Immunoglobulin in Medical Definition

Proteopathy

... AL (light chain) amyloidosis ( primary systemic amyloidosis ) Monoclonal immunoglobulin light chains AH (heavy chain) amyloidosis immunoglobulin heavy chains AA (secondary) amyloidosis Amyloid A protein ...

Artificial induction of immunity

... to a polysaccharide from the capsule of the bacteria responsible for most lobar pneumonia . Temporarily-induced immunity See also immunoglobulin . Image:Http://upload.wikimedia.org/wikipedia/commons/f/f2/Platypus.jpg Platypus: monotremes lack placental transfer of immunity ...
Immunoglobulin in Medical Dictionary

Antibody

... Ask the Doctor Forums ] ... Antibody (Ab) immunoglobulin (Ig) immunoglobulin s (antibodies) are protein s produced by plasma ... s or organ isms. Antibodies are also called immunoglobulin s. - Antibody deposits resulting from a ...

Gamma

... Electrophoresis - Urine , IEP - Urine , immunoglobulin Electrophoresis - Urine , Urine immunoglobulin Electrophoresis Pictures & Images Female ... from pooled human plasma . See Globulins, immunoglobulin s. Gamma globulins. All of the gamma ...

Gamma globulin

... from pooled human plasma . See Globulins, immunoglobulin s. gamma globulin Blood protein that ... gamma globulin , also called intravenous immunoglobulin (IVIG), Common Misspellings: kawasaki diease, ... little (if any) gamma globulin (IgG) and other immunoglobulin s in the blood stream. This is due to the ...

Immunoelectrophoresis

... Electrophoresis - Urine , IEP - Urine , immunoglobulin Electrophoresis - Urine , Urine immunoglobulin Electrophoresis Pictures & Images ... ... levels of specific types of protein s called immunoglobulin s. ...

Immunoglobulin

... immunoglobulin M: Abbreviated IgM. A major class of immunoglobulin s. IgM includes the antibodies that are usually ... All of MedicineNet For: search help ... immunoglobulin E (IgE) Reagin, Reaginic Antibody One of ...

Fetal development

... of a pregnancy before fetal development has reached 20 weeks. immunoglobulin D (IgD) immunoglobulin receptor found on the surface of B-cells . May function during fetal ...

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Immunoglobulin in Biological News

Scientists discover a molecular scaffold that guides connections between brain cells

... Huangs team established that a protein from the immunoglobulin family directs one group of cerebellar neurons to connect with a specific part of Purkinje cells. immunoglobulin proteins are best known for acting as antibodies ... is that there is a lot of capacity for variety in immunoglobulin molecules, Dr. Huang explains. In the nervous ...

Sugar linkage could lead to better treatment for autoimmune diseases

... University. The work revolves around immunoglobulin G (IgG), the most abundant antibody in blood plasma. Intravenous immunoglobulin (IVIG) has within it a trace amount of a very ... These carbohydrate structures are linked to the immunoglobulin and referred to as glycans, and on the tip of ...

Reversing cognitive deficits: Injectable antibody may attack source of problem

... Louis University researchers have found. The protein -- part of the immunoglobulin M (IgM) class -- is an antibody that grabs onto the amyloid beta protein ... findings are surprising because IgM is five times bigger than the antibody immunoglobulin G (IgG), which has already been studied as a potential therapy for ...

Gene decides whether coral relative will fuse or fight

... different varieties that predict how Hydractinia colonies will interact with one another, they show. The gene sequence is most closely related to the immunoglobulin (Ig) superfamily of proteins, which include antibodies of the mammalian immune system. "Relationships have often been suggested between cnidarian ...

Tailor-made recombinant proteins in mammals

... interested in attaching to a protein." Because of their obvious therapeutic importance, the researchers used antibodies in their first tests. immunoglobulin G (IgG) is the most widely used, clinically important type of antibody. For example, it can be rendered anti-inflammatory by chemically modifying ...

Munich researchers discover key allergy gene

... Mnchen and Dr. Thomas Illig from the Helmholtz Zentrum Mnchen found that certain variations of the FCER1A gene decisively influence the production of immunoglobulin E (IgE) antibodies. IgE antibodies are a particular type of antibody that is normally used to protect against parasites. In Western lifestyle ...

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Immunoglobulin in Biological Technology

China Biologic Products Announces Strong 2008 Results

... increased by 29.7%. The Company's approved human immunoglobulin for intravenous injection product ... The Company's approved human hepatitis B immunoglobulin product represented 6.9% of revenues in 2008, as ... is used mainly to increase blood volume while immunoglobulin is used for disease prevention and treatment. ...

International Guidelines for First-Line use of Freelite(TM) in Diagnosis and Management of Multiple Myeloma to be Published in "Leukemia"

... of multiple myeloma (MM) and related disorders. immunoglobulin free light chains (FLC) in serum are an ... bone marrow biopsies; - for some intact immunoglobulin MM patients in remission, relapse is ... The underlying bone marrow disorder/monoclonal immunoglobulin producing disorder is known by many different ...

China Biologic Products Reports Record Third Quarter 2007 Results

... with higher profit margins. Human albumin, Human immunoglobulin for Intravenous Injection and Human Rabies immunoglobulin contributed 61.9%, 11.1% and 15.2% to the ... is used mainly to increase blood volume while immunoglobulin is used for disease prevention and treatment. ...

OMT announces a breakthrough in the development of a novel human antibody platform

... Inc. to knockout a gene encoding rat immunoglobulin. The mutations in rat immunoglobulin caused no off-target effects in other genes, and offspring of the ... to create a knockout, OMT used a new ZFN-mediated technique to generate immunoglobulin knockout rats. ZFNs are engineered proteins that induce double-strand ...

China Biologic Products Receives $5.3 Million Order from Largest Biopharmaceutical Distributor in India

... under the Company's own brand. The order for China Biologic's Human immunoglobulin (ph4) for IV Injection (IVIG) 5g/100ml product will be delivered to the ... statements," including statements regarding: the significance of the human immunoglobulin product order to be shipped to India and its impact on the Company's own ...

China Biologic Products Completes Acquisition of 90% Controlling Interest in Chongqing Dalin Biologic Technologies Co., Ltd.

... Immunoglobulin, Human Hepatitis B Immunoglobulin, Human Tetanus immunoglobulin and Human Rabies Immune Globulin. Based on management's analysis of NICPBP ... human albumin products are mainly used to increase blood volume and its immunoglobulin products are used for the treatment and prevention of diseases. ...

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Immunoglobulin in Biological Products

Anti-J Chain Monoclonal Antibody, Unconjugated, Clone M19/9J from CHEMICON

Description:... This antibody is specific for human J-chain as defined by ELISA assay using purified human immunoglobulin fragments as solid phase target ....
Company:CHEMICON

Affi-Prep Protein A Support, 25 ml from Bio-Rad

Description:... For affinity chromatography, Affi-Prep protein A media yield highly purified immunoglobulins (IgG), selectively remove IgG prior to analysis of other immunoglobulin classes, or adsorb immune complexes for antigen purification. Protein A binds to the Fc region of immunoglobulins, especially IgG from mammalian ...
Company:Bio-Rad

REC. PROTEIN G - SEPHAROSE from Invitrogen

Description:... mammalian immunoglobulins. Protein A and Protein G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants and other biological fluids. These reagents are also commonly used to ...
Company:Invitrogen

REC. PROTEIN G - SEPHAROSE from Invitrogen

Description:... mammalian immunoglobulins. Protein A and Protein G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants and other biological fluids. These reagents are also commonly used to ...
Company:Invitrogen

REC PROTEIN A - SEPHAROSE from Invitrogen

Description:... mammalian immunoglobulins. Protein A and Protein G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants and other biological fluids. These reagents are also commonly used to ...
Company:Invitrogen

REC PROTEIN A - HRP from Invitrogen

Description:... mammalian immunoglobulins. Protein A and Protein G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants and other biological fluids. These reagents are also commonly used to ...
Company:Invitrogen

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Immunoglobulin in Biological Definition

Antibody

... parent immunoglobulin. A crude estimation of immunoglobulin levels can be made by protein electrophoresis . ... ) a very high concentration of one particular immunoglobulin will show up as a monoclonal band. ... antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in ...

Varicella zoster virus

... , notably sodium hypochlorite . Within the body it can be treated by a number of drugs and therapeutic agents including aciclovir , zoster immunoglobulin (ZIG), and vidarabine . A live attenuated VZV Oka/Merck strain vaccine is available and is marketed under the trade name Varivax . It was ...
Immunoglobulin in Biological Dictionary

Somatic hypermutation

... have been well ... Somatic hypermutation of immunoglobulin genes is linked to transcription initiation. ... Somatic Hypermutation , immunoglobulin information including symptoms, causes, diseases, ... describes studies on somatic hypermutation of immunoglobulin genes ... formulation of a new model of somatic ...

B lymphocytes

... differentiated "resting" stage. ... Only B Lymphocytes that have immunoglobulin receptors for non- self ... ... lymphocytes are: B lymphocytes ... (CTLs) ... B lymphocytes . colostrum. cytokines. granuloma. immunoglobulin ... Lymphocytes may be T cells or B cells. T Cells: T cells are ...

Spleen

... is located between the fundus of the stomach and the diaphragm, while ... Here, the spleen processes foreign antigen and produces specific immunoglobulin ... Although people can survive without a spleen because other organs can take ... Conditions & Treatments " Medical Conditions " What ...

Site-specific recombination

... allows ... Site - Specific ... of three site - specific recombination systems: the integration ... transposase, and the recombination of immunoglobulin genes during ... Escherichia coli Xer site - specific recombination acts to convert circular DNA ... ( B) Model of Xer site - specific ...

Polyclonal Antibody

... Polyclonal antibodies (or antisera) are antibodies that are derived from different B cell lines. They are a mixture of immunoglobulin molecules secreted against a specific antigen, each recognizing a different epitope. Polyclonal antibodies This article deals exclusively with ...

Polyclonal antibodies

... Polyclonal antibodies (or antisera) are antibodies that are derived from different B cell lines. They are a mixture of immunoglobulin molecules secreted against a specific antigen, each recognizing a different epitope. Pacific Immunology provides custom antibody production, ...

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