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Hypothalamus in Medical News

Action of ghrelin hormone increases appetite and favors accumulation of abdominal fat

... have discovered that, besides stimulating the hypothalamus to generate appetite, ghrelin also acts on the ... that intervene in the control of appetite in the hypothalamus and, at the same time, can act on other organs, ... should block the action of ghrelin both on the hypothalamus and on the accumulation of abdominal fat. At ...

JCI online early table of contents: July 10, 2008

... provided insight into a molecular pathway in the hypothalamus that contributes to the development of insulin ... The importance of SK6 activation in the hypothalamus in suppressing the ability of insulin to prevent ... it was shown that enforced SK6 activation in the hypothalamus had the same effects as feeding rats a high-fat ...

Deep brain stimulation may improve memory

... a variety of conditions. For example, DBS of the hypothalamus has been used to treat cluster headaches and ... potential appetite suppressant sites in the hypothalamus by stimulating electrode contacts that had been ... readily induced the memories were located in the hypothalamus and estimated to be close to the fornix, an ...

Deep Brain Stimulation May Improve Recall

... memory, suggests a Canadian study that found that DBS of the brain's hypothalamus unexpectedly prompted detailed memories in a patient. DBS -- which ... researchers also found that three weeks of continuous stimulation of the hypothalamus led to significant improvements in the patient's results on two learning ...

Study provides documentation that tumor 'stem-like cells' exist in benign tumors

... clues about several types of stem cells. The pituitary gland, situated at the base of the brain behind the nose, is stimulated by hormones from the hypothalamus gland to produce a variety of hormones that control other glands throughout the body. About half of all pituitary adenomas which arise from ...

Cancer survivors at greater risk of birth complications; special monitoring needed

... to the deleterious effects of abdominal radiotherapy on reproductive function, radiotherapy to the head can also cause problems by causing the hypothalamus to reduce the production of follicle stimulating hormone and luteinizing hormone, both important in promoting ovulation. "We believe that it is ...

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Hypothalamus in Medical Technology

VAI Finding Could Lead to New Drugs for Anxiety, Depression

... and we are the first to determine the structural details necessary to develop an ideal drug." CRF is a hormone and neurotransmitter secreted by the hypothalamus area of the brain and is involved in stress response. CRF has been associated with anxiety, depression, and related disorders. The hormone's receptor ...

FASgen Announces New Discovery for Treatment of Stroke

... area of that research has been for the treatment of metabolic disease disorders, including obesity. As the regulation of appetite is centered in the hypothalamus in the brain, research was undertaken to evaluate the safety of the Company's compounds in the brain. An unexpected and significant discovery ...

Elixir Pharmaceuticals Presents Additional Preclinical Data Demonstrating the Potential of Ghrelin Antagonism to Regulate Metabolism, Body Weight and Glycemic Control

... key role in metabolism and energy storage. Ghrelin is a naturally occurring hormone secreted by the stomach, which acts primarily at the level of the hypothalamus in the brain. In the first presentation, Elixir scientists explored whether ghrelin exerts a direct effect on adipocytes (fat cells) and if ...

Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Association's Annual Meeting

... in metabolism and energy storage. A naturally occurring hormone produced in the stomach, ghrelin is believed to act primarily at the level of the hypothalamus in the brain, which governs metabolism. Elixir scientists have previously demonstrated that, compared to normal (control) mice, ghrelin receptor ...
Hypothalamus in Medical Products

Vasopressin (AVP) RIA Test

Description:... Arginine vasopressin (AVP), also known as Antidiurectic Hormone (ADH), is synthesized in the hypothalamus and is transported via exonal flow to the posterior pituitary for storage and eventual release. AVP secretion is regulated by changes in blood ...
Company:Diagnostic Systems Laboratories, Inc.

Leptin IRMA Test

Description:... state of these individuals may be related to a leptin resistance and an inability of leptin to enter the cerebral spinal fluid to reach sites in the hypothalamus to regulate appetite. Involvement of a leptin receptor or carrier protein in this kind of regulation has been suggested. Serum leptin levels follow ...
Company:Diagnostic Systems Laboratories, Inc.

Leptin Soluble Receptor ELISA Test

Description:... signals the brain to counteract weight loss by increasing feed intake and decreasing energy expenditure [3]. Leptin operates at the level of the hypothalamus and acts via specific receptors to control the expression of the appetite stimulator, neuropeptide Y (NPY). This feedback mechanism provided by ...
Company:Diagnostic Systems Laboratories, Inc.

Leptin ELISA Test

Description:... state of these individuals may be related to a leptin resistance and an inability of leptin to enter the cerebral spinal fluid to reach sites in the hypothalamus to regulate appetite. Involvement of a leptin receptor or carrier protein in this kind of regulation has been suggested. Serum leptin levels follow ...
Company:Diagnostic Systems Laboratories, Inc.

ACTH RIA Test

Description:... circulation, where it has a half-life of approximately 20 minutes [1]. ACTH is secreted in response to corticotropin-releasing factor (CRF) from the hypothalamus [1]. The actions of CRF are augmented by arginine vasopressin. Several other stimulatory and inhibitory factors, including catecholamines and ...
Company:Diagnostic Systems Laboratories, Inc.

TSH ELISA Test

Description:... transport and resultant thyroid hormone synthesis [2]. TSH secretion is stimulated by thyrotropin-releasing hormone (TRH) which is secreted by the hypothalamus and is regulated at both the pituitary and hypothalamic levels by thyroid hormones. Low levels of thyroid hormones lead to increased TSH secretion ...
Company:Diagnostic Systems Laboratories, Inc.

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Hypothalamus in Medical Definition

Depolarization-induced suppression of inhibition

... ubiquitous phenomenon and has been demonstrated in other areas of the brain such as the basal ganglia , the cortex , the amygdala , and the hypothalamus (Katona et al. 2001, Jo et al. 2005, Bodor et al. 2005, Matyas et al. 2006) DSI mediation by endocannabinoids DSI was thought to ...
Hypothalamus in Medical Dictionary

Hypothalamus

... hypothalamus Definition: The hypothalamus is an area of the brain that produces hormone s ... release of hormone s from various glands . hypothalamus The ...

Pituitary gland

... ) portion stores hormone s produced in the hypothalamus . Damage to the pituitary gland can be ... gland is not making enough hormone s or if the hypothalamus (another part of the brain's hormone ... of the brain in response to signals from the hypothalamus gland in the brain. GROWTH HORMONE - A ...

Gonad

... hormone (Gn-RH) agonists. To trigger a new menstrual cycle, your hypothalamus manufactures gonad otropin-releasing hormone (Gn-RH). Gonad ... of gonad otropin releasing hormone (GNRH), normally produced in the hypothalamus . The qualitative urine human chorionic gonad otropin ( HCG ) test ...

Hypothalamic

... Hypothalamic dysfunction involves the region of the brain called the hypothalamus . This area is located behind the eyes and helps control the pituitary ... (CT or MRI scans) are performed to detect tumor s in the pituitary, hypothalamus , liver , ovary or testes . These scans should be repeated ...

LH response to GnRH

... of gonad otropin releasing hormone (GNRH), normally produced in the hypothalamus . LH response to GnRH is a test of the ability of the pituitary gland ... a gonad otropin releasing hormone (GnRH, a hormone produced in the hypothalamus ). This ability is assessed indirectly. ...

Testes

... or secondary hypogonadism (problem is with the pituitary gland or the hypothalamus ). Congenital absence of both testes . anorexia nervosa An eating ... (CT or MRI scans) are performed to detect tumor s in the pituitary, hypothalamus , liver , ovary or testes . body, it grows in the naso pharynx ...

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Hypothalamus in Biological News

JCI table of contents: Aug. 9, 2007

... and in the region of the brain known as the hypothalamus are lean because they eat less and move around ... were associated with decreased signaling in the hypothalamus through a protein known as PPAR-alpha. Administration of a PPAR-alpha agonist into the hypothalamus increased the amount mice lacking FAS ...

Brain background to body mass

... use stores of energy, such as fat tissue. A part of the brain called the hypothalamus controls many of our basic functions such as body temperature, hunger and ... the status quo. "Very occasionally, mutations in genes active in the hypothalamus have dramatic consequences for weight gain," explains Dr Ruth Loos, a ...

Stress puts double whammy on reproductive system, fertility

... returned to normal by the next day. Chronically stressed rats, however, were left with longer-term elevations of RFRP levels in the dorsomedial hypothalamus area of the brain, and suppression of activity in the reproductive axis - the hypothalamus-pituitary-gonadal hormone cascade - that is associated ...

USC researchers present diabetes findings at American Diabetes Association Scientific Sessions

... vein sensors may connect to or signal the brain to respond to hypoglycemia. The symposium will take place on Sunday, June 7 (Session: Beyond the hypothalamus Other Sites Involved in Sensing and Responding to Recurrent Hypoglycemia; Peripheral vs. Central Sensors Importance of Rate of Glucose Drop). ...

What happens when we sleep

... the circadian rhythm. With Drs. Oum Hassani and Maan Gee Lee, Dr. Barbara Jones at the MNI were studying a structure in the brain called the lateral hypothalamus (LH) known to be critical for maintaining wakefulness. MCH neurons, co-distributed with Orx neurons, constitute less than 10% of the LH. Previous ...

Brain enzyme may play key role in controlling appetite and weight gain

... an almond-sized structure located deep within the brain that controls body temperature, hunger, and thirst. Specialized nerve cells in the hypothalamus sense whether the body contains adequate amounts of nutrients and stored body fat. The cells then send out signals telling other parts of the brain ...

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Hypothalamus in Biological Technology

Laser dissection of depression

... high activity of the PVN is a pivotal characteristic of depression. The hypothalamus consists of a large number of very small specialized cell groups that all ... used. Corticotrophin-releasing factor (CRF) cells in the PVN of human hypothalamus are the central driving force of the stress response and are hyperactive ...

Global Biopharmaceutical Leader in Peptide Research Expands Commitment in San Diego/U.S. With New R&D Facility and Ready-To-Market Prostate Cancer Treatment Degarelix

... and Gastroenterology. Since the 1950s, the company has pioneered the research, development and marketing of pharmaceutical products based on natural, hypothalamus and pituitary-based peptide hormones. Headquartered in Switzerland, Ferring has commercial subsidiaries in over 45 countries and its products ...

RNArticles: Keeping RNA Intact Prior to RNA Isolation - RNAlater

... in different regions of rat brain, Dr. Dunn-Meynell collected tissue punches of the arcuate nucleus of the hypothalamus and the ventromedial thalamus. Punches were derived from rat brain tissue that was frozen and cryosectioned ...
Hypothalamus in Biological Products

Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description:... state of these individuals may be related to a leptin resistance and an inability of leptin to enter the cerebral spinal fluid to reach sites in the hypothalamus to regulate appetite. Involvement of a leptin receptor or carrier protein in this kind of regulation has been suggested. Serum leptin levels follow ...
Company:Diagnostic Systems Laboratories, Inc.
Hypothalamus in Biological Definition

Limbic system

... of a "limb", hence the name) fornicate gyrus archicortex hypothalamus : controls the autonomic nervous system and regulates blood pressure , ... and thus regulates the endocrine system. (Not all authors regard the hypothalamus as part of limbic system.) The limbic system is among the oldest ...

Brain

... tectum midbrain tegmentum crus cererbri prosencephalon diencephalon epithalamus pineal gland thalamus hypothalamus pituitary gland telencephalon archipallium basal ganglia caudate nucleus substantia nigra striatum ...

Homeostasis

... variety of ions . Most of these organs are controlled by hormones secreted from the pituitary gland , which in turn is directed by the hypothalamus . See also Acclimatization Biological rhythm Metabolism Apoptosis Aging Balance Self-organization ...

Kidney

... sodium ion absorption in the convoluted tubule. Any rise or drop in blood osmotic pressure due to a lack or excess of water is detected by the hypothalamus , which notifies the pituitary gland via negative feedback . The pituitary gland secretes antidiuretic hormone, otherwise known as vasopressin ...

Neurotransmitter

... generally used as a neurotransmitter in cells involved in emotional regulation. Dopamine acts as the neurotransmitter of choice for cells in the hypothalamus which are effectively the brain's reward system, however it is also involved in the control of movement. Neurotransmitters which have these types ...

Signal transduction

... the hormone concentration, which is regulated by : Biosynthesis and secretion of hormones in the endocrine tissue . As an example, the hypothalamus receives information, both electrical and chemical. It produces releasing factors that affect the hypophysis and make it produce glandotrope ...

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Hypothalamus in Biological Dictionary

Hypothalamus

... The hypothalamus is a portion of the brain that contains a number ... One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system ... hypothalamus n. The part of the brain that lies below the ...

Infundibulum

... of the pituitary stalk, containing nerve tracts passing from the hypothalamus to the nervous lobe ... infundibulum ... Information about ... from between the chiasma and ... The infundibulum connects the hypothalamus to the pituitary gland, or hypophsis. ... ... as to whether the ...

Posterior

... system. Despite its name, the posterior pituitary gland is not a gland, per se; rather, it is largely a collection of axonal projections from the hypothalamus ... Information about posterior in the free online English dictionary and ... posterior - located at or near or behind a part or near the ...

Pituitary gland

... gland , or hypophysis, is an endocrine gland about the size of a pea and weighing 0.5 g (0.02 oz.). It is a protrusion off the bottom of the hypothalamus at the base of the brain, and rests in a small, bony cavity (sella turcica) covered by a dural fold ... The pituitary is a small, pea-sized ...

Ovulation

... ovulation ( ′ävyə′lāshən ) ( physiology ) Discharge of an ovum or ovule from the ovary. ... The process of ovulation is controlled by the hypothalamus of the ... Brief and Straightforward Guide: What is Ovulation ? ... As a woman begins her period, her body is in the follicular phase of ...

Limbic system

... in the human brain involved in emotion, motivation, and emotional association with memory. ... consists of the cerebrum, thalamus, and hypothalamus (part of the limbic system ) ... Brain Stem: Underneath the limbic system is the brain stem. ... The limbic system is a mid-brain ...

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