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Hypoglycemia in Medical News

Tight Management of Type 1 Diabetes Worth the Effort

... -- low blood sugar (hypoglycemia). Severe hypoglycemia that resulted in either a coma or seizure ... of severe episodes, but a lack of awareness of hypoglycemia and hypoglycemia remain big problems. The bottom line, she ...

Low Blood Sugar in Hospital Tied to Higher Death Risk for Diabetics

... hypoglycemia likely a sign of additional illness, suggest ... in patients who'd had hypoglycemia. "We think hypoglycemia likely was a marker for severity of illness," ... with diabetes received treatment with insulin. hypoglycemia was defined as a blood sugar reading of less than ...

Novo Nordisk Insulin Analogs Have Proven Safety Profiles

... Important Safety Information: hypoglycemia is the most common adverse effect of insulin ... Mix 70/30. As with all insulins, the timing of hypoglycemia may differ among various insulin formulations. ... Mix 70/30 are contraindicated during episodes of hypoglycemia and in patients hypersensitive to any of their ...

Two-Year Data Show Investigational Drug Liraglutide More Effective at Lowering Blood Sugar Than Glimepiride

... in the glimepiride group (+1.1 kg). hypoglycemia is a condition where blood sugar levels become too low. Minor hypoglycemia was more than six times less frequent in the ... tolerability of liraglutide The rate of minor hypoglycemia was statistically significantly lower with both ...

Use of Mealtime Pramlintide Added to Basal Insulin Showed Similar Improvements in Glycemic Control Compared to Rapid-Acting Insulin, With Lower Risk of Hypoglycemia and Without Weight Gain: Data Presented at ADA 2009

... SYMLIN recipients had a lower incidence of hypoglycemia (55 percent vs. 82 percent). Use of SYMLIN or ... in patients with type 1 diabetes. When severe hypoglycemia associated with SYMLIN use occurs, it is seen ... hours following a SYMLIN injection. If severe hypoglycemia occurs while operating a motor vehicle, heavy ...

Comprehensive Review on Sulfonylureas in the Latest Issue of Diabetic Hypoglycemia (05 June 2009)

... The latest issue of the online journal Diabetic hypoglycemia ( http://www.hypodiab.com ) features an ... prevention of SIH. This issue of Diabetic hypoglycemia also includes a case study on recurring hypoglycemia associated with glibenclamide, by Professor ...

Amylin Pharmaceuticals to Present Compelling Efficacy and Safety Data From Diabetes Programs at ADA 2009

... in patients with type 1 diabetes. When severe hypoglycemia associated with SYMLIN use occurs, it is seen ... hours following a SYMLIN injection. If severe hypoglycemia occurs while operating a motor vehicle, heavy ... sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, ...

Severe Low Blood Sugar Ups Older Diabetics' Dementia Risk

... Study finds being hospitalized for hypoglycemia linked to mental decline TUESDAY, ... during a Tuesday teleconference. "Episodes of hypoglycemia may be associated with neurological consequences ... for dementia. This study seems to suggest that hypoglycemia is one of the reasons people with type 2 ...

NICE SUGAR: Intensive insulin therapy risks

... therapy significantly increases the risk of hypoglycemia in critically ill patients, found a new study in ... of intensive insulin therapy on vital status and hypoglycemia in the ICU setting," write Dr. Donald Griesdale, ... patients. There was a 6-fold increased risk of hypoglycemia compared to the control treatment. The study ...

New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes

... with type 2 diabetes and was not associated with hypoglycemia (low blood sugar). In this study of 206 patients aged 65 to 96 years, there were no reports of hypoglycemia in either the JANUVIA or the placebo groups. ... known to cause hypoglycemia, the incidence of hypoglycemia was increased over that of placebo. Therefore, a ...

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Hypoglycemia in Medical Technology

5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH

... with a significantly greater incidence of severe hypoglycemia than was insulin glargine (11.1% vs 7.6% ... p=0.0439) and mean yearly rates of symptomatic hypoglycemia (7.08+/-16.49 vs 5.13+/-12.79, p=0.0017). ... with a significantly greater incidence of severe hypoglycemia than was insulin glargine (11.1% vs 7.6% ...

Exenatide Once Weekly Provided Sustained Improvements in Glycemic Control With Weight Loss Over Two Years: DURATION-1 Interim Long-Term Data Presented at ADA 2009

... were receiving exenatide once weekly. No severe hypoglycemia was observed. The safety profile of patients ... sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, ... with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To ...

Two-Year Data Show Investigational Drug Liraglutide More Effective at Lowering Blood Sugar Than Glimepiride: Oral 162

... in the glimepiride group (+1.1 kg). hypoglycemia is a condition where blood sugar levels become too low. Minor hypoglycemia was more than six times less frequent in the ... tolerability of liraglutide The rate of minor hypoglycemia was statistically significantly lower with both ...

Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients

... in significantly less weight gain and risk of hypoglycemia for adult patients with diabetes. The data were ... and severe (4 percent vs. 10 percent, p=0.0066) hypoglycemia compared to the BPA 70/30 group. Mean changes ... interval [CI] 0.271, 0.831; p=0.0091) and total hypoglycemia (OR 0.488; CI 0.278, 0.856; p=0.0124). ...

Use of Mealtime SYMLIN(R) Compared to Rapid-Acting Insulin for Diabetes Therapy Intensification in Patients With Type 2 Diabetes Using Basal Insulin

... glucose control without weight gain or hypoglycemia compared to the use of rapid-acting insulin (RAI) ... patients (82 percent) and no severe hypoglycemia was experienced in either group. At week 24, ... in patients with type 1 diabetes. When severe hypoglycemia associated with SYMLIN use occurs, it is seen ...

DiObex, Inc. Awarded Patent for the Prevention of Insulin-Induced Hypoglycemia

... or DIO-901, in the prevention of insulin-induced hypoglycemia in diabetes patients. The patent grants DiObex ... and is sometimes fatal." Insulin-induced hypoglycemia is the limiting factor in the glycemic management ... development for the prevention of insulin-induced hypoglycemia in type 1 diabetes mellitus in an extended ...

Retrospective Analysis Finds That Initiation of Insulin Glargine in Patients With Type 2 Diabetes was Associated With a Lower Incidence Rate of Myocardial Infarction as Compared With NPH Insulin

... the NPH group had at least one medical claim for hypoglycemia (Odds Ratio = 0.85, 95% CI: 0.76 - 0.95). Although hypoglycemia incidence was associated with an over 40% ... of MI (HR=1.42; 1.11-1.83), the difference in hypoglycemia between the two insulin groups did not ...

Exenatide Once Weekly Provided Superior Glucose Control Compared to Lantus(R) in Head-to-Head DURATION-3 Study

... once weekly experienced less confirmed hypoglycemia: the incidence of hypoglycemia was 4 percent with exenatide once weekly versus 19 percent with Lantus for ... along with other parameters of glucose control, cardiovascular health, hypoglycemia and patient-reported outcomes. Subjects in both treatment groups are ...

Spherix Announces Positive Phase 2 Study Results

... from the study, as well as any having one or more episodes of severe hypoglycemia within six months prior to entry into the study, or currently diagnosed as having hypoglycemia unawareness. In this trial, Naturlose was safe and well tolerated. ...

Meta-Analysis of Clinical Data Showed No Increased Risk of Cardiovascular Events Associated With Exenatide Use: Data Presented at ADA 2009

... BYETTA provides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, with potential weight ... When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To reduce this possibility, ...

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Hypoglycemia in Medical Products

ACS:180 C-Peptide Assay

Description:... For The Detection Of Serum C-Peptide Levels. Clinical Uses Of C-Peptide Measurement: Evaluating patients with fasting hypoglycemia Assisting in the classification of diabetes mellitus Differentiating insulin dependent patients from noninsulin - dependent patients ...
Company:Siemens Medical Solutions Diagnostics

ADVIA Centaur C-Peptide Assay

Description:... For The Detection Of Serum C-Peptide Levels. Clinical Uses Of C-Peptide Measurement: Evaluating patients with fasting hypoglycemia Assisting in the classification of diabetes mellitus Differentiating insulin dependent patients from noninsulin - dependent patients ...
Company:Siemens Medical Solutions Diagnostics

AutoDELFIA® Insulin Kit

Description:... and heparin plasma using the AutoDELFIA Automatic Immunoassay System. The assay is used in the investigation, diagnosis and treatment of diabetes and hypoglycemia (low blood glucose level). The analytical sensitivity is typically better than 0.5 U/mL (3 ....
Company:PerkinElmer Life And Analytical Sciences, Inc.
Hypoglycemia in Medical Definition

Pathology

... ) Pancreas Diabetes mellitus ( type 1 , type 2 , coma , angiopathy , ketoacidosis , nephropathy , neuropathy , retinopathy ) - hypoglycemia - Hyperinsulinism - Zollinger-Ellison syndrome Parathyroid Hypoparathyroidism ( Pseudohypoparathyroidism ) - Hyperparathyroidism ( ...
Hypoglycemia in Medical Dictionary

Hyperglycemia

... after meals, but it carries a risk of hypoglycemia . 7. Combination A single pill that combines a ... sugar ) Glucose , decreased: systemic hypoglycemia ( low blood sugar ), bacterial or fungal ... developing short-term complications such as hypoglycemia and hyperglycemia and to delay or slow the ...

Hypoglycemia

... hypoglycemia results when your body's glucose is used up ... insulin is released into the blood stream. hypoglycemia in the newborn can be caused by conditions that: ... ), inhibit the use of glucose by the body. hypoglycemia is commonly associated with diabetes . However, ...

Insulinoma

... amount of insulin sulfonylurea-induced hypoglycemia ... Insulinoma The tumor makes too much ... sugar in the blood , a condition called hypoglycemia . Insulinoma ( tumor s of the pancreas ... is treated with surgery to remove the tumor . hypoglycemia caused by problems with the ad renal or ...

Insulin Shock

... : Insulin Shock , Low Blood Sugar Definition hypoglycemia occurs when your body's blood sugar , or ... term insulin shock is used to describe severe hypoglycemia that results in unconsciousness . Insulin ... sugar Causes, incidence , and risk factors: hypoglycemia results when your body's glucose is used up ...

Insulin

... is an excessively low blood sugar level ( hypoglycemia ), usually lower than 50 mg/dL. Insulin is ... drops too low, you'll develop the symptoms of hypoglycemia , a potentially serious condition that is most ... amount of insulin sulfonylurea-induced hypoglycemia ... Question.com > Encyclopedia > Medicine > ...

Low blood sugar

... LOW BLOOD SUGAR NOT NECESSARILY " hypoglycemia " Question: I'm a 58-year-old man, and my family ... : Insulin Shock , Low Blood Sugar Definition hypoglycemia occurs when your body's blood sugar , or ... term insulin shock is used to describe severe hypoglycemia that results in unconsciousness . Low blood ...

Coma

... Poinsettia plants are another potential danger. In severe cases, hypoglycemia can progress to seizures and coma . You develop symptoms of keto ... A nonlife-threatening condition. Not malignant. Not cancer ous. In hypoglycemia , cells cannot function normally, and symptoms develop such as ...

Dextrose

... Source: First DataBank, Inc. A child with signs or symptoms of hypoglycemia needs emergency medical attention. Treatment may include intravenous saltwater (saline) and sugar ( dextrose ). ARTICLE TOOLS Print ... hypoglycemia - low blood sugar ; usually treated with IV fluids containing dextrose ...

Sugar

... experience a variety of symptoms. LOW BLOOD SUGAR NOT NECESSARILY " hypoglycemia " Question: I'm a 58-year-old man, and my family doctor recently asked me ... blood sugar and cholestorol levels ... Severe low blood sugar ( hypoglycemia ) Doll-like features in children, including puffy cheeks, a thin chest ...

Acidosis

... glucose test - hemoglobin A1c test for diabetics * - high in diabetes , causing keto acidosis * - low in diabetes ( insulin -reaction hypoglycemia ) * - - self blood glucose monitoring ... ...

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Hypoglycemia in Biological News

Study shows CGM devices also benefit people with type 1 diabetes

... Today, the JDRF study has shown that, with CGM, hypoglycemia can be reduced while maintaining excellent blood ... with glucose values in the potentially dangerous hypoglycemia range. The authors demonstrated a number of ... sugar levels without increasing the frequency of hypoglycemia in adults over 25 years of age in a randomized ...

USC researchers present diabetes findings at American Diabetes Association Scientific Sessions

... How Do Beta Cells Respond to Increased Demand in People? Lessons from Pregnancy, Gestational Diabetes, and the Evolution of Type 2 Diabetes). hypoglycemia Casey Donovan, Ph.D., professor of kinesiology and biology, will discuss his research on the role of the brain and the portal vein in sensing and ...

Master gene plays key role in blood sugar levels

... called a coactivator fast for a day, their blood sugar levels plummet. If they go another day without food, they will die. The severity of the hypoglycemia (low blood sugar) was unexpected, said Dr. Bert W. O'Malley, chair of molecular and cellular biology at Baylor College of Medicine and senior author ...

Fear of hypoglycemia a barrier to exercise for type 1 diabetics

... study, published in the November issue of Diabetes Care , a majority of diabetics avoid physical activity because they worry about exercise-induced hypoglycemia (low blood sugar) and severe consequences including loss of consciousness. Despite the well-known benefits of exercise, this new study builds on ...

JDRF to provide $1M in funding to SmartCells, Inc.

... currently available insulins, SmartInsulin is designed to maintain continuous, tight control of blood glucose levels while reducing the risk of hypoglycemia like the pancreas does automatically in the absence of diabetes. As part of the agreement, JDRF will provide $1 million in first-year funding to ...

New once-a-week treatment for type 2 diabetes developed by Mount Sinai researcher

... defined by reaching target glucose levels. Patients treated with Exenatide once weekly also experienced fewer side effects, had no increased risk of hypoglycemia (decrease in blood sugars) and saw reductions in body weight. Dr. Drucker has studied the gut hormone GLP-1 for over 20 years. Multiple drugs ...

Treatment corrects severe insulin imbalance in animal studies

... beta cells in the pancreas. Insulin levels rage out of control and severely reduce blood glucose, a condition called hypoglycemia. If untreated, hypoglycemia may cause irreversible brain damage or death in children. Congenital HI occurs in an estimated one in 50,000 U.S. children, with a somewhat higher ...

Glucose triggers brain cell death in rats after hypoglycemic coma

... to extremely low levels –?a condition known as hypoglycemia –?and cause hypoglycemic coma, resulting in ... was only when we gave them glucose to reverse the hypoglycemia that the oxidative stress occurred. This was a ... bad for rat brains. The way we treat patients for hypoglycemia may have to be reevaluated." Swanson adds ...

Blood sugar's manufacture limited by building blocks' supply

... found that mice with a targeted deletion of KLF15 display severe hypoglycemia after an overnight fast. They further found evidence that defective amino acid breakdown promotes the development of fasting hypoglycemia in the mutant animals by limiting the availability of a glucose substrate ...
Hypoglycemia in Biological Technology

New Data From Head-to-Head Phase 3 Trial Demonstrate That Liraglutide is More Effective Than Exenatide in Treatment of Type 2 Diabetes

... blood glucose control and also had less minor hypoglycemia than those treated with exenatide." Fasting ... and/or a sulphonylurea. The overall rate of hypoglycemia in the study was low. Liraglutide patients experienced significantly less minor hypoglycemia compared to those on exenatide. Nausea was the ...

New Drug Application for Exenatide Once Weekly Accepted for Review by FDA

... BYETTA provides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, with potential weight ... When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To reduce this possibility, ...

Glenmark's Novel Molecule for Diabetes, Melogliptin to Enter Phase III Trials

... best-in-class in achieving glycemic control with low incidence of hypoglycemia and neutral effect on body weight - Global Phase III trials likely to ... In addition, patients taking Melogliptin experienced low incidence of hypoglycemia and neutral effect on body weight. In this 12-week, randomized, ...

Exenatide Once Weekly New Drug Application Submitted to FDA for Type 2 Diabetes

... BYETTA provides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, with potential weight ... When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To reduce this possibility, ...

Exenatide Clinical Data Analysis Shows No Increased Risk of Cardiovascular Events

... BYETTA provides sustained A1C control and low incidence of hypoglycemia when used with metformin or a thiazolidinedione, with potential weight ... When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To reduce this possibility, ...

Amylin Pharmaceuticals to Present Promising Data From Diabetes and Obesity Programs at ADA 2008

... hypoglycemia, particularly in patients with type 1 diabetes. When severe hypoglycemia associated with SYMLIN use occurs, it is seen within three hours following ... thiazolidinedione. BYETTA provides sustained A1C control, low incidence of hypoglycemia when used with metformin or a thiazolidinedione, and progressive weight ...

DiObex and Camurus Sign License Agreement for the Development of DIO-901 in FluidCrystal(R) Extended Release Technology

... Development program for prevention of insulin-induced hypoglycemia in diabetes SAN FRANCISCO and LUND, ... formulation of low dose glucagon for the prevention of insulin-induced hypoglycemia in patients with diabetes. "Intensive glycemic control is beneficial for ...

Anesiva Grants Specific-Use License of Its Needle-Free Drug Delivery Technology to Particle Therapeutics for Diabetes Drug

... delivery system for glucagon, a hormone commonly used for the treatment of hypoglycemia associated with Type 1 and Type 2 diabetes. "This agreement exemplifies ... Director of Particle Therapeutics. "Current methods of treating diabetic hypoglycemia require the mixing of glucagon powder with a sterile saline solution, ...

Hospira Announces Plans to Integrate Symbiq(R) and EndoTool(R) Technologies

... appropriate precision to manage blood glucose levels in a variety of hospital settings. Overly aggressive insulin therapy can increase the risk of hypoglycemia (low blood glucose), an independent risk factor for mortality (2)(3). EndoTool software can operate on a hospital's existing computer system, and is ...

Amylin Pharmaceuticals and Eli Lilly Provide Context for FDA Alert for BYETTA

... add-on therapy for people currently using metformin, a sulfonylurea, or a thiazolidinedione. BYETTA provides sustained A1C control, low incidence of hypoglycemia when used with metformin or a thiazolidinedione, and progressive weight loss. BYETTA was approved in April 2005 and has been used by approximately ...
Hypoglycemia in Biological Definition

Diabetes mellitus

... coma 3.5 Hyperosmotic diabetic coma 3.6 hypoglycemia 4 Long-term complications 5 ... , or delivering a baby with macrosomia or hypoglycemia . Criteria for diagnosis Diabetes ... it is less common in type 1 diabetics. hypoglycemia ...

Insulin

... 5 Signal transduction 6 The brain and hypoglycemia 7 Diseases and syndromes caused by an ... restore satisfactory blood glucose levels after hypoglycemia must be quick and effective because of the ... are indeed generally efficient, and symptomatic hypoglycemia is found almost entirely in diabetics using ...
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