gradient

New understanding of cell movement may yield ways to brake cancer's spread

...e cell, enzymes degrade the PIP3 lipid, creating a gradient from one end of the cell to the other. It is this PIP3 lipid gradient that sets the cell into motion toward the right direction. The PIP3-binding portion of DOCK180 sense...

Researchers make headway in mystery of migraines

...otassium from outside, the sodium pump maintains a gradient of potassium, which is critical for the propagation of electrical signals along nerve cells. Like an air conditioner in the heat of summer, the sodium pump is a massive energy hog, consuming around 30% of the energy produced by the cell in order to p...

Gradient guides nerve growth down spinal cord

... University of Chicago researchers reported that a gradient of biochemical signals known as the Wnt proteins a...m previous studies, Zou and colleagues knew that a gradient of various Wnt proteins, including Wnt4, formed along the spinal cord around the time of birth. Here...

U-M scientists discover identifying markers for primitive blood-forming stem cells

...t markers we use to purify HSCs are expressed as a gradient from high to low across the hematopoietic cell hierarchy," says Omer H. Yilmaz, co-first author and a student in the Medical School's M.D./Ph.D. program. "What's really exciting about this finding is that now we have markers that turn on and off abru...

Tropical Atlantic cooling and African deforestation correlate to drought, report scientists

...and cools relative to the ocean, there is a larger gradient between the ocean temperature and the land causing less moisture to be pulled from the ocean air toward the land. Weldeab and his colleagues studied cores from beneath the ocean floor of the Gulf of Guinea, in the tropical Atlantic just off the coas...

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gradient at Biology Products

Mastercycler ep gradient S thermal cycler from Eppendorf North America

...lock: up to 6C/s Freely programmable temperature gradient over 12 rows A gradient range of up to 24C...

Finnigan Pocket Surveyor from Thermo Scientific

...y to connect directly to their Surveyor quaternary gradient pump and/or variable wavelength detector....

NanoFrontier LD LC/MS System from Hitachi High Technologies America

...: * 890-1713 L-2730 loading pump * 890-1712 L-2720 gradient pump * 890-1710 L-2700 nano flow pump * 890-1711 L-2710 organizer * 890-1715 L-2750 autosampler * NanoLC control panel software...

Extracti-Gel D Detergent Removing Gel AffinityPak Columns from Pierce Biotechnology, Inc.

...cies of Acetylcholinesterase (AchE) before density gradient centrifugation. Features: Brings efficiency, speed and high protein recovery to detergent removal Allows relatively small detergent molecules to enter the gel matrix, where they interact with a specially developed ligand capable of removing them f...

NADPH-cytochrome c reductase Colorimetric Assay Kit from Sigma-Aldrich

...isolation and subcellular fractionation by density gradient separation Assaying NADPH-cytochrome c reductase levels in various sources after intoxication by drugs or challenge by xenobiotics...

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gradient at Biology Technology

Highest Transfection Efficiency of an Endotoxin-Sensitive Mammalian Cell Line

...graphy, magneticbeads, and cesium chloride density gradient centrifugation. Plasmid yields andpurity (as judge... lower than DNA purified by cesium chloridedensity gradient centrifugation. The StrataPrep-purified plasmid yielded thehighest efficiency transfection of an end...

Automated Fluorescent-Tag Cycle Sequencing

... Top Assembly, which is available for both gradient and nongradient RoboCycler 40 and 96 models, elimi...and reproducibly. The new Hot Top Assembly forboth gradient and nongradient RoboCycler 96 temperature cyclers eliminates theneed for oil or wax overlays on reac...

Effects of Thermal Cycler Well-To-Well Temperature Uniformity on PCR Results

...ace of the block;this design creates a temperature gradient from the center to the edges of theblock. Moreover, to ramp temperatures up and down quickly, use of the Peltiermodules requires that the blocks mass be limited. Maintaining a consistent temperature across a thermal block is easier whenthe exposed s...

Oil-Free PCR Using the Hot Top Assembly

...cler 40 or 96 units are also available. Using both gradient andsingle-temperature RoboCycler 96 models, we sho...eproducible whether the annealing block was run in gradient orsingle-temperature mode, an important feature for optimizing annealingtemperatures. When used for ...

Performance Comparisons of Commercial RT-PCR Systems

...ations were carried out in Stratagenes RoboCycler gradient 96 temperature cycler fitted with a Hot Top assembly, using 200-lthin-walled PCR tubes. The temperature cycling parameters for all targetsincorporated the following. For cDNA synthesis, cycling included one cycle at37C for 15 minutes (1.8-kb target) ...

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gradient at Biology Definition

Redox

...hich then contributes to the creation of a proton gradient , which drives the synthesis of Adenosine triphosphate (ATP) and is maintained by the reduction of oxygen. In animal cells, mitochondria perform similar functions. The term redox state is often used to describe the balance of NAD + /NADH and ...

Proton pump

...lar compartment, thereby creating a difference or gradient in both pH and electrical charge (ignoring differences in buffer capacity ) and tending to establish an electrochemical potential . In bacteria , mitochondria and other ATP-producing organelles, reducing equivalents provided by electron ...

Proton-motive force

...of energy as a combination of a proton and voltage gradient across a plasma membrane . In eukaryotes the Proton-motive force exists across the inner mithochondrial membrane. It is generated by energy from the citric acid cycle and is utilized in the synthesis of ATP via ATP Synthase . In plants, the ...

Potential energy

...rce field can be re-obtained by taking the vector gradient of the potential field. For example, gravity is a conservative force . The work done by a unit mass going from point A with U = a to point B with U = b by gravity is ( b - a ) and the work done going back the other way is ( a - ...

Cell membrane

...ally moves molecules against their electrochemical gradient , a process that would be entropically unfavorable were it not stoichiometrically coupled with the hydrolysis of ATP. This coupling can be either primary or secondary. In the primary active transport, transporters that move molecules against thei...

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gradient at Biology Dictionary

Vertebrates

... the most well-studied organ ism. electrochemical gradient The sum of the gradients of concentration and of electric charge of an ion across a membrane. Full article >>> Animal - kingdom composed of multicellular organ isms divided into two division s: vertebrates and in vertebrates ...

Vacuoles

...ly water. Water tends to move along concentration gradient s into vacuoles . Full article >>> Vacuoles are membrane-bounded compartments within some eukaryotic cells that can serve a variety of secretory, excretory, and storage functions. Full article >>> vacuoles Membr...

Transport protein

...cell , moving particles against the concentration gradient . [edit] See also ... Full article >>>...embrane ; usually moved against the concentration gradient with the aid of specific transport protein s. Full article >>>...

Trans

... molecule across a membrane down a concentration gradient which does not require the input of energy. -pathy disease of, suffering pathogenic Disease-causing. Full article >>> Dispersal (sensu ecology ): the trans port of propagules away from the parent. Diversity: a) the total number ...

Thylakoid

...s to electron trans fer via an electrochemical pH gradient across a membrane (inner mitochondrial membrane , bacteria l plasma membrane , or thylakoid membrane). Full article >>> Cyanobacteria are close to the ancestors of chloroplasts , but cyanobacteria maintain fully functional re...

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gradient at Medicine News

Chemical Signaling Helps Regulate Sensory Map Formation In The Brain

...journal Nature. Here, the researchers show that a gradient of a molecule known as Wnt3 counterbalances anothe...agues reveal a new role for Wnts. They show that a gradient of Wnt3 along the medial-lateral axis within the developing brain is the opposing regulating force, ...

Americans-Not So Healthy After All

... sicker than the English. … Second, the SES-health gradient is also not a reporting mirage… Instead, the SES-health gradient appears with equal force in either self-reports or biological measures of health.” br>...

Sperm Cells attracted By Ovary Scent, Even in Weakened State

...ofluidic device the ability to generate a chemical gradient with transporting sperm cells to evaluate sperm ch...al approach for precisely controlling the chemical gradient and accurately tracking chemotactic events. This combination led to greater repeatability in the exp...

Location Influences Mortality Rate of Cardiovascular Diseases

...uative Sciences said that there is an East to West gradient in terms of the death rate from heart disease. Canada has about 33 million people spread over 6,000 miles. Hence the health facility in every place differs widely. He said that people in rural areas are disadvantaged that those in the cities. Dr. And...

Experiments In Outer Space To Determine single Cell Survival

... nanostructure by expelling water and developing a gradient in the local pH. This in turn influences lipid organization and the form of the silica nanostructure, reduces stress, and ultimately improves the living conditions of the ensconced cellular tenants. The work was initially funded by Sandia's Laborat...

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gradient at Medicine Products

LocaLisa Intracardiac Navigation System

...al fields. This electrical field creates a voltage gradient along its axis, allowing the LocaLisa system to calculate the catheter's position. Intracardiac catheters can be tracked, and various points of interest can be tagged throughout the procedure. The computer software allows the user to target a specif...

Magnetom C! MRI System

...nnel coils and a sophisticated multichannel RF and gradient system....

MagPro

...ro has an LED display showing the realized current gradient di/dt, providing a precise and reproducible value for the stimulation strength. The coil temperature is displayed on an easy to read 6 level bar graph, and as for all Dantec stimulators, MagPro has a build-in thermo-sensor that prevents triggering i...

Synergy Ultrapure Water System

...atography Biochemical experiments Isocratic or gradient solutions for HPLC analysis Culture media for bacteriological analysis or cell cultures Solutions for spectrophotometry, spectroscopy, and other analytical techniques Features Feedwater specific purification packs snap-in and snap-out for re...

Synergy 185 UV Ultrapure Water System

...atography Biochemical experiments Isocratic or gradient solutions for HPLC analysis Culture media for bacteriological analysis or cell cultures Solutions for spectrophotometry, spectroscopy, and other analytical techniques Features Feedwater specific purification packs snap-in and snap-out for re...

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gradient at Medicine Technology

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gradient at Medicine Definition

Osmotherapy

...motherapy usually consists of creating a chemical gradient against the tissue to be treated, to assist with chemical movement. For example, osmotherapy can be used to treat a patient who has cerebral hemorrhage . This might include the use of mannitol to maintain the brain's homeostasis . Extern...