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gout in Medical News

Savient Pharmaceuticals Receives Complete Response Letter from U.S. Food and Drug Administration for KRYSTEXXA(TM)

... (pegloticase) as a treatment for chronic gout in patients refractory to conventional therapy. ... so we can provide this therapy to those chronic gout patients who are suffering from this crippling, ... enzyme intended for the treatment of chronic gout in patients refractory to conventional therapy. ...

The Gout & Uric Acid Education Society (GUAES) Announces New Survey Results Highlighting Major Gaps in Public Awareness of Gout

... New Findings Released on the Third Annual gout Awareness Day (May 22) NEW YORK, May 22 /PRNewswire/ -- The gout & Uric Acid Education Society announced today ... to being "not at all knowledgeable" about gout and just over 70% did not know ...

More Vitamin C May Mean Less Chance of Gout

... was less than 250 milligrams a day, the risk for gout was 17 percent lower among men with a daily ... 500 mg increase in vitamin C intake, the risk for gout fell 17 percent, the researchers calculated. ... milligrams a day had a 34 percent lower risk of gout than men who did not take vitamin C supplements. ...

FDA approves ULORIC (febuxostat) for the chronic management of hyperuricemia in patients with gout

... patients who have hyperuricemia associated with gout a new treatment option that helps prevent uric ... doctor during a flare not understanding that gout is a chronic disease that needs to be managed on ... recognize that a goal in the treatment of chronic gout is the reduction and maintenance of serum uric ...

Pegloticase BLA Filing Accepted for Priority Review by FDA

... Application for Treatment-Failure gout Granted Priority Review EAST BRUNSWICK, ... a novel biological drug for treatment-failure gout (TFG) patients. The FDA also granted the ... designation by the FDA. Treatment-failure gout occurs in patients who have failed to normalize ...

Savient's Board of Directors Forms a Board Committee to Oversee the Regulatory and Pre-Launch Activities for Pegloticase

... of therapy available to the treatment-failure gout population and we believe the work of this ... major improvement in the treatment of this orphan gout population. I look forward to working with the ... absence of other therapies for treatment-failure gout patients, are forward-looking statements. These ...

Studies examine treatment for gout and the condition's protective effects

... The goal in treating patients with gout is to reduce acute attacks by lowering serum ... of febuxostat, a new drug being developed for gout that was recently approved for use in Europe, and ... years. Another study examined the link between gout and PD in individuals 65 years and older. The ...

New Drug Helps Relieve Gout

... Sept. 3 (HealthDay News) -- An experimental gout drug called pegloticase lowered levels of uric ... treatment, 88 percent of the patients experienced gout flares and some also experienced mild to moderate ... Academy of Family Physicians has more about gout . -- Robert ...

Basketball Star Details His Struggle With Gout

... And he's got gout. "I had no idea what gout was," Cheeks said, describing his first encounter ... New York City to mark the second annual National gout Awareness Day, sponsored by the gout & Uric Acid Education Society (GUAES). The ...

NBA Coach Maurice Cheeks Teams Up with the Gout & Uric Acid Education Society (GUAES) to Call a 'Time Out for Gout'

... Cheeks partners with rheumatology experts on gout Awareness Day to share his story and correct ... All-Star Maurice Cheeks is partnering with the gout & Uric Acid Education Society (GUAES) to spread the word about gout -- a common and intensely painful form of ...

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gout in Medical Technology

Arthritis Advisory Committee Recommends FDA Approval of Febuxostat for the Treatment of Hyperuricemia in Patients With Gout

... the management of hyperuricemia associated with gout in more than 40 years. The FDA will ... and symptoms, and diarrhea. About gout and Uric Acid Uric acid is an ... greater the risk for developing gout. gout is the most common inflammatory arthritis in men ...

Ardea Biosciences Advances Lead Product Candidate for the Treatment of Gout, RDEA594, Into Phase 1 Clinical Trial

... organization, and the importance we place on our gout program -- a program we intend to expand with ... flares), and kidney damage (nephropathy). While gout is a treatable condition, there are limited ... the treatment of hyperuricemia associated with gout in the past 40 years About RDEA594 RDEA594, ...

Ardea Biosciences Identifies Lead Development Candidate for Gout, RDEA594

... for the treatment of patients with gout, RDEA594. gout is a painful and debilitating disease that is ... flares), and kidney damage (nephropathy). While gout is a treatable condition, there are limited ... treatment of hyperuricemia associated with gout in the past 40 years. About RDEA594 RDEA594 ...

Ardea Biosciences, Inc. Announces New Clinical Development Program Directed Toward the Treatment of Gout

... 1 Clinical Study - Phase 2 Efficacy Study in gout Patients to Start in the First Half of ... Drug Administration for the underlying cause of gout in the past 40 years, there is a significant need ... Phase 2, dose-ranging clinical efficacy study in gout patients with hyperuricemia in the first half ...

New Report by BioTrends Research Group to Highlight the Launch of ULORIC(R) (febuxostat)

... is indicated for the chronic management of hyperuricemia associated with gout and represents the first product for gout that has been approved in over forty years. LaunchTrends(TM): ...

Savient Provides Update on Pegloticase BLA

... Patients in the every 2 week dose regimen have demonstrated statistically significant clinical improvements including the reduction and resolution of gout tophi. Other statistically and clinically meaningful improvements included decreases in tender or swollen joint counts, reduction in flare ...

Savient Announces FDA's Advisory Panel to Review Pegloticase for Treatment-Failure Gout Patients

... -- Savient Pharmaceuticals, Inc. (Nasdaq: SVNT ) today announced that its biologics license application (BLA) for pegloticase for treatment-failure gout will be reviewed by the Arthritis Advisory Committee appointed by the U.S. Food and Drug Administration (FDA) on March 5, 2009 as required for a drug ...

September 2008 Mayo Clinic Health Letter Highlights Cataract Removal, Severe Headache and Dual Energy X-Ray Imaging

... if a kidney stone is made of uric acid or if it contains calcium. Uric acid stones can be treated with medication, avoiding surgery. -- Detecting gout -- A dual energy X-ray image shows the presence and location of gout. Standard X-rays, even combined with a needle biopsy, don't always provide the ...

Michael J. Fox Foundation Announces $5.6-Million Award for Phase 2 Clinical Trial Studying Neuroprotective Potential of Inosine

... elevated urate levels are known to carry certain health risks, only some of which have been definitively characterized to date. Kidney stones and gout are known risks; cardiovascular disease is a possible risk. (In the clinical trial, safety measures will be in place to help avoid these conditions, ...
gout in Medical Dictionary

Arthritis

... l tissue within joints . Arthritis , gout : Joint inflammation caused by uric acid ... . Arthritis "1 Arthritis "2; Rheumatoid gout [Kellogg] Rheumatoid Arthritis "1 Articular ... [Kellogg] Chronic Rheumatism [Kellogg] gout "1 ...

Gout

... gout Overview gout is a condition in which the body has a problem in the handling of uric acid . People with gout either produce too much uric acid or more ...

Hyperuricemia

... Hyperuricemia does not inevitably lead to gout . In fact, less than 20% of the hyperuricemic ... of uric acid in the blood , often producing gout . PurineA white crystalline substance that is one ... , hyperkalemia , and hyperphosphatemia. gout is caused by too much uric acid in the blood ...

Joint

... S " Arthritis "1 Arthritis "2; Rheumatoid gout [Kellogg] Rheumatoid Arthritis "1 Articular ... [Kellogg] Chronic Rheumatism [Kellogg] gout "1 gout "2 [Kellogg] Bursitis ... joint The ...

Joints

... " Arthritis "1 Arthritis "2; Rheumatoid gout [Kellogg] Rheumatoid Arthritis "1 Articular ... [Kellogg] Chronic Rheumatism [Kellogg] gout "1 gout "2 [Kellogg] Bursitis ... Joints are the ...

Knee

... -- including rheumatoid , osteoarthritis , and gout , or other connective tissue disorders like ... with your opposite hand . The symptoms of gout --severe pain , usually in the hand or foot ... with your knee bent at a 30 degree angle. gout usually begins with an acute attack of pain , ...

Pseudogout

... Pseudogout is so named for its similarity to gout . Like gout , pseudogout causes sudden, severe pain in a ... recurrent arthritis clinically similar to gout ; features include calcification of cartilage ....

Psoriatic arthritis

... numbers of white blood cells may indicate gout , pseudogout , inflammatory forms of arthritis ... Uric acid crystals in the joint indicate gout . most common forms are osteoarthritis (this article), rheumatoid arthritis (which see), gout (which see), and ankylosing spondylitis (which ...

Uric acid

... of purines that are part of many foods . In gout , there are frequently, but not always, elevated ... of attacks is usually reduced dramatically. gout is caused by uric acid crystals forming in the ... p-aminohipp uric acid ; ... Alcohol can cause gout because it can keep your body from getting rid ...

Ankylosing spondylitis

... attack about 1. Examples of other forms of arthritis include gout , ankylosing spondylitis , and arthritis that occurs after an injury ... arthritis , ankylosing spondylitis , psoriatic arthritis , lupus , gout , pseudogout ). However, it also can be related to poorly fitting ...

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gout in Biological News

New player in commitment to life as a fat cell

... byproduct uric acid, XOR had earlier been implicated in gout, said Jeffrey Friedman of The Rockefeller University, senior author of the study. gout is a painful type of arthritis that results when uric acid crystals build up in the joints. "These findings are novel in many aspects," said ...

Viagra's hidden help for wildlife

... large TCM clinic in Hong Kong. The men were questioned about their previous and current use of TCM and Western treatments for arthritis, indigestion, gout and impotence. The study's lead authors are Dr Bill von Hippel, a psychologist from the University of New South Wales (Sydney, Australia), and his ...
gout in Biological Technology

FDA Appointed Arthritis Advisory Committee Recommends U.S. Food and Drug Administration Approval for KRYSTEXXA(TM) for Refractory Chronic Gout

... of refractory chronic gout. Refractory chronic gout or treatment failure gout (TFG) is gout in patients who have failed to normalize serum ...

Savient Pharmaceuticals Reports First Quarter 2009 Financial Results

... disability in patients with treatment failure gout appeared in the Journal of Rheumatology. ... the disabling aspects of the treatment failure gout population." Financial Results of ... KRYSTEXXA(TM) (pegloticase) for treatment failure gout has reported positive Phase 1, 2 and 3 clinical ...

Disability and Poor Quality of Life Associated With Treatment Failure Gout Patients

... of Life and Disability in Treatment Failure gout Patients EAST BRUNSWICK, N.J., May 5 ... study of patients with treatment failure gout (TFG). The objective of the study was to ... of life in patients with treatment failure gout and appears in the May issue of the Journal of ...

FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout

... patients who have hyperuricemia associated with gout a new treatment option that helps prevent uric ... doctor during a flare not understanding that gout is a chronic disease that needs to be managed on ... recognize that a goal in the treatment of chronic gout is the reduction and maintenance of serum uric ...

Savient's Pegloticase Data in Treatment-Failure Gout Patients Presented at 72nd Annual Meeting of the American College of Rheumatology Conference

... pivotal clinical studies in treatment-failure gout (TFG) patients was presented at scientific ... that included the effect of pegloticase on gout tophi, gout flares, and the immune response to ... of their signs and symptoms of treatment-failure gout with continuing pegloticase treatment, extending ...

Ardea Biosciences' Advances RDEA806 Into Phase 2a Proof-of-Concept Study for Gout

... in men over 40. The Company also announced that gout specialist, Dr. Fernando Perez-Ruiz in Spain, ... in the target population of patients with gout using its prodrug, RDEA806. Enrollment in the ... League Against Rheumatism (EULAR) Task Force for gout and with the Outcome Measures for Rheumatic ...

The Law Offices of Brian D. Witzer Wins 6+ Million Dollar Verdict

... that she did not have gout. The doctor claimed that she told him she had gout and described pain in her toe consistent with gout. He prescribed Allopurinol in order to prevent a recurrence of an acute gout attack. Plaintiff made a statutory offer to compromise the claim in ...

Savient Announces New Date for FDA Arthritis Advisory Panel Review of KRYSTEXXA(TM) for Treatment Failure Gout

... (TM) (pegloticase), a novel biological drug for treatment failure gout (TFG) patients, will be reviewed by the Arthritis Advisory Committee ... development candidate, KRYSTEXXA(TM) (pegloticase) for treatment failure gout has reported positive Phase 1, 2 and 3 clinical data. The KRYSTEXXA Phase ...

Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology

... Arthritis - - RDEA594 Shows Promise as an Effective Treatment for gout - SAN DIEGO, June 11 /PRNewswire-FirstCall/ -- Ardea Biosciences, ... Biosciences' President and CEO. "In addition, we are on track to begin two gout trials, a Phase 1 trial with RDEA594 in the second half of this year and a ...

Savient Submits Biologics License Application (BLA) for pegloticase

... President and Chief Executive Officer. "This filing reflects our commitment to changing the paradigm of therapy available to the treatment-failure gout population and brings us one step closer to commercializing this drug and offering a solution to patients who suffer from this debilitating ...
gout in Biological Definition

Colchicine

... to treat rheumatic complaints and especially gout , it was also prescribed for its cathartic and ... extract was first described as a treatment for gout in De Materia Medica of Padanius Dioscorides ... pain relieving and anti-inflammatory effects for gout were linked to it binding with the protein ...

Purine

... tissue turnover) are metabolized by several enzymes , including xanthine oxidase , into uric acid . High levels of uric acid can predispose to gout when the acid crystalizes in joints; this phenomenon only happens in humans and some animal species (e.g. dogs) that lack an intrinsic urease ...

Tubulin

... play a role in forming the mitotic spindle during mitosis. Pharmacology Tubulins are targets for anticancer drugs like taxol . The anti- gout agent colchicine binds to tubulin and inhibits microtubule formation, arresting neutrophil motility and decreasing inflammation . ...
gout in Biological Dictionary

Uric acid

... amount of uric acid in a blood sample. ... If gout remains untreated, these uric acid crystals ... can crystallize to form ... uric acid gout food high in uric acid level danger and side ... Video of Uric Acid / Tophi Deposits caused by gout Attacks in Dissected Big Toe. ... Sometimes uric ...

Purine

... into serum uric acid (which is can cause gout when ... Purine rich foods are on the top of ... ... Diet is not the only solution for reducing gout attacks, but avoiding purine -rich foods is recommended. ... a person with gout should avoid purine -rich foods. ... What ...

Colchicine

... is used to prevent or treat attacks of gout (also ... Colchicine does not cure gout or take the ... Physician reviewed colchicine ... Colchicine has long been used to relieve acute gout attacks. ... Colchicine may be an option for ...
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