Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory
... very earliest processes of how a human gamete and gonad (ovary and testis) develops. Many scientists believe that environmental chemical pollutants that mimic the action of hormones (so called endocrine disrupting chemicals) might interfere with human development at this stage and cause congenital abnorma...Olfactory system detects pheromones that control reproduction
...s the estrus cycle. In males, the hormone controls gonad function, including spermatogenesis and testosterone production. "One of the classical dogmas is that LHRH neurons receive inputs from the vomeronasal system. For example, textbooks on reproductive physiology say that pheromonal modulation of reprod...Study finds how organs monitor themselves during early development
...ications that extend beyond understanding of how a gonad such as the ovary develops," explains Dr. Ruth Lehmann, Ph.D., Julius Raynes Professor of Developmental Genetics and Howard Hughes Medical Investigator. "In every organ, may it be a gonad, a liver, or a thymus, different tissues contribute to the org......n the early stages of development in the mammalian gonad before it commits to either a male testis or a fem...f this equilibrium is tipped in favor of Wnt4, the gonad develops into an ovary, while an Fgf9 victory leads to the formation of a testis. What tips the bal...Long-life genes - A new way to combat cancer…
...mor cells, when left undisturbed, break out of the gonad and fill the body, killing the worm at around 9 days old age. They then studied the effects of a few different 'longevity' genes in the tumor-affected animals, to assess the influence on lifespan and tumor growth. All of the longevity mutations te......ications that extend beyond understanding of how a gonad such as the ovary develops," explains Dr. Ruth Lehmann, Ph.D., Julius Raynes Professor of Developmental Genetics and Howard Hughes Medical Investigator. "In every organ, may it be a gonad, a liver, or a thymus, different tissues contribute to the org......otential gonadotoxic factors – harmful to the male gonad – were identified. For the purposes of this study, wet heat exposure was defined as the immersion of the body in a hot tub, heated Jacuzzi or bath at a temperature warmer than body temperature for 30 minutes or more per week for at least three mont...