Navigation Links
Glycoprotein in Medical News

Novel vaccine concept developed by scientists at the Wistar Institute

... secret is using a herpes simplex protein called glycoprotein D to block a specific receptor molecule on ... One of thee inhibitory signals is blocked by glycoprotein D from herpes virus. In a study that will be ... are vaccine delivery systems, made by fusing the glycoprotein D with genes from target antigens increase the ...

Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive Imaging of Patient and Tumor Status Will Determine Clinical and Commercial Success

... pi (GSTP1); glycinamide ribonucleotide formyltransferase (GARFT); glycoprotein NMB; B-lymphocyte stimulator (BLyS); gonadotropin-releasing hormone ... TRAIL-r2; tumor suppressor candidate 2 (TUSC2), FUS1; tumor- associated glycoprotein 72 (TAG-72); vitamin D receptor (VDr); Von Willebrand factor; X-linked ...

Ashwell receptor reduces mortality during sepsis

... host factors involved in blood coagulation, including platelets and a glycoprotein called von Willebrand Factor (vWF). When this occurs, the Ashwell receptor recognizes the change in the glycoprotein structure and removes those pro-coagulation factors from circulation ...

HORIZONS AMI trial data will help set guidelines

... we sought to determine whether using bivalirudin instead of heparin and glycoprotein IIb/IIIa inhibitors in patients with a heart attack after angioplasty ... either the standard anticoagulant regimen of unfractionated heparin plus a glycoprotein IIb/IIIa inhibitor or bivalirudin alone. The patients are to be followed ...

Horizons AMI trial data to be presented at TCT 2007

... in patients with stable coronary artery disease instead of heparin and glycoprotein IIb/IIIa inhibitors reduces bleeding, which has been associated with ... to receive either the standard anticoagulant unfractionated heparin plus a glycoprotein IIb/IIIa inhibitor or bivalirudin alone. The patients are to be followed ...

For ST-Elevation Myocardial Infarction (STEMI), Interviewed Experts Indicate That The Medicines Company's Angiomax/Angiox Has Efficacy Advantages Over Sales-Leading ReoPro

... because it is associated with significantly lower mortality rates than the standard PCI adjunctive therapy of unfractionated heparin and a glycoprotein IIb/IIIa inhibitor," said Decision Resources Analyst Jeremy Goldman, M.D. "This mortality reduction is associated with lower rates of bleeding with ...

More>>

Glycoprotein in Medical Technology

CellCyte Genetics Corporation Selects Washington University School of Medicine to Perform Study on CellCyte's Glycoprotein Products in Heart Attack Disease Model

... The goal of the study is to investigate the efficiency of CellCyte's glycoprotein products in a preclinical model of myocardial infarction (heart attack). ... will continue to advance the research and development efforts for our glycoprotein products," noted Ronald W. Berninger, Ph.D., Chief Scientific Officer at ...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

... combines a small peptide that activates the immune system with a small peptide from a disease-related protein, such as a herpes simplex virus (HSV) glycoprotein to make a vaccine that induces a defined immune response. Last month Dr. Kenneth S. Rosenthal, Professor of Microbiology, Immunology and ...

CuraGen to Present CR011-vcMMAE Data at ASCO

... titles, dates, and times of the presentations are as follows: #9032 A phase I/II study of CR011-vcMMAE , an antibody-drug conjugate targeting glycoprotein NMB in patients with advanced melanoma. Sunday, May 31, 2009, poster presentation from 8:00 AM - 12:00 PM with a discussion session from 11:30 AM - ...

Medarex Announces Preclinical Data from Multiple Research Programs Demonstrating Anti-Tumor Activity in Cancer

... important new treatment for liver cancer. Efficacy and Toxicity of anti-mesothelin antibody drug conjugate (Abstract #3235) Mesothelin is a glycoprotein over-expressed on mesotheliomas and other cancers, including ovarian and lung cancer, and because of its limited expression in normal tissue, it is ...

Schering-Plough Announces Results of the Early ACS Trial

... L. Kristin Newby, MD, associate professor of medicine at Duke Clinical Research Institute, presented the results of the nearly 9,500-patient Early glycoprotein IIb-IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS) study, which was designed to determine whether routine early use ...

XTL Biopharmaceuticals Announces the Acquisition of the Use Patent on Recombinant Erythropoietin (rHuEPO) for the Treatment of Multiple Myeloma

... Closing is expected to take place in the second or third quarter of 2009. ABOUT ERYTHROPOIETIN (EPO) Erythropoietin (EPO) is a glycoprotein cytokine produced mainly by the kidney and is the major growth regulator of the erythroid lineage. EPO stimulates erythropoiesis by binding to its ...
Glycoprotein in Medical Products

HSV Typing ASR

Description:... The HSV Typing ASR contains primers and a FAM-labeled probe targeting the glycoprotein D gene of HSV Type 1 as well as primers and an Alexa 532-labeled probe designed to detect the glycoprotein G gene of HSV Type 2. This ASR requires an instrument that can detect FAM, ...
Company:Cepheid

MGB Alert HSV 1, 2 Typer ASR*

Description:... of various pathogens including sequences associated with BK virus, Enterovirus, VZV and others. These reagents detect for the following sequence: glycoprotein D. HSV Typer ASR differentiates HSV 1 from HSV 2 sequences by melt curve analysis and is a combined single primer and probe mix. *Analyte ...
Company:Nanogen, Inc.

MBG Alert HSV 1, 2 Ensemble ASR*

Description:... of various pathogens including sequences associated with BK virus, Enterovirus, VZV and others. These reagents detect for the following sequence: glycoprotein D. HSV ensemble ASR detects both sequences but does not differentiate. *Analyte Specific Reagents. Analytical and performance ...
Company:Nanogen, Inc.

SHBG IRMA Test

Description:... Human sex hormone-binding globulin (SHBG) is a serum glycoprotein which binds several sex steroids with relatively high specificity and low capacity, including testosterone and dihydrotestosterone (combined 95% ...
Company:Diagnostic Systems Laboratories, Inc.

PAPP-A, Ultra-Sensitive ELISA Test

Description:... Pregnancy-associated plasma protein A (PAPP-A) is a large placenta-derived glycoprotein [1]. PAPP-A is produced in high concentrations by placental trophoblast cells, and is released into the maternal circulation in increasing ...
Company:Diagnostic Systems Laboratories, Inc.

PAPP-A ELISA Test

Description:... Pregnancy-associated plasma protein A (PAPP-A) is a large placenta-derived glycoprotein [1]. PAPP-A is produced in high concentrations by placental trophoblast cells, and is released into the maternal circulation in increasing ...
Company:Diagnostic Systems Laboratories, Inc.

More>>

Glycoprotein in Medical Definition

Pathology

... ) Glycosaminoglycan Mucopolysaccharidosis - 1:Hurler / Hunter - 3:Sanfilippo - 4:Morquio - 6:Maroteaux-Lamy - 7:Sly glycoprotein Mucolipidosis - I-cell disease - Pseudo-Hurler polydystrophy - Aspartylglucosaminuria - Fucosidosis - Alpha-mannosidosis - Sialidosis ...
Glycoprotein in Biological News

New windows opened on cell-to-cell interactions

... allowing precise optical measurements of the orientation of the molecule. Electron microscopy revealed the presence of rigid, rod-like brushy glycoprotein (sugar-containing compounds) -- 30 billionths of a meter long -- similar to natural cell-surface proteins. Interaction between cells occurs when ...

American Chemical Society's Weekly PressPac -- Dec. 17, 2008

... them unusable for transplantation. To address this challenge, the researchers developed synthetic antifreeze materials, called C-linked antifreeze glycoprotein analogues (C-AFGP). These proteins contain a sugar coating and have custom-tailored antifreeze activity. Now the scientists describe the ...

Sarcospan, a little protein for a big problem

... severe form of muscular dystrophy. In Duchenne muscular dystrophy (DMD), the mutated dystrophin protein fails to anchor correctly to its membrane glycoprotein complex. And without this anchoring, muscle cells experience severe contraction-induced damage. Sarcospan is part of the anchoring complex, but ...

Scripps research scientists reveal key structure from ebola virus

... Nature article, though, provides hope that one day modern medicine will have more to offer. The structure of the antibody together with the viral glycoprotein helps reveal the mechanisms by which the molecules assemble on the viral surface and helps explain how the pathogen evades and exploits the human ...

Mate choice in plants

... attached carbohydrate components, have been found to be associated with pollen tubes. These proteins, transmitting-tract-specific (TTS), 120 kDa glycoprotein (120K), and pistil extension-like protein III (PELPIII), may play a role in movement of S-RNases into the pollen tube vacuoles and, if necessary, ...

Findings released from 1 of the largest percutaneous coronary intervention trials ever

... rate of adverse clinical events, a lower rate of major bleeding, and a lower mortality rate than those who were treated with a regimen of heparin and glycoprotein IIb/IIIa inhibitors (GPI). In the landmark global trial, bivalirudin was compared to heparin plus GPI in more than 3,600 patients with ST-segment ...

More>>

Glycoprotein in Biological Technology

Bruker Announces Availability of New HUPO World Congress Proteomics Posters on Web Site

... of ConA Capturing, ICPL Labeling and MALDI-TOF MS Poster T341 -- Full glycoprotein Characterization by the Combination of High Resolution-CID and Ion Trap-ETD Poster T345 -- Automated LC-MALDI Analysis of Glycopeptides from glycoprotein Digests using DHB as Matrix Poster T348 -- Glycosylation Profiling of ...

GeoVax Labs, Inc. Provides Clinical Studies Update

... protective T cell response. The Env protein is designed to elicit a protective antibody response against the natural form of the virus envelope glycoprotein as well as protective T cells. "Vaccine trials can be a slow process," said Harriet Robinson, Ph.D., developer of the vaccine and Senior V.P. ...

Oncothyreon announces presentation of long-term Stimuvax data at World Conference on Lung Cancer

... Stimuvax Stimuvax is an investigational therapeutic cancer vaccine designed to induce an immune response to cancer cells that express MUC1, a glycoprotein antigen widely expressed on common cancers. MUC1 is over-expressed on many cancers such as lung cancer, breast cancer, prostate cancer and colorectal ...

Oncothyreon announces initiation of Phase 3 trial of Stimuvax in breast cancer

... Stimuvax Stimuvax is an investigational therapeutic cancer vaccine designed to induce an immune response to cancer cells that express MUC1, a glycoprotein antigen widely expressed on common cancers. MUC1 is over-expressed on many cancers such as lung cancer, breast cancer, prostate cancer and colorectal ...

Oncothyreon announces clinical data from three product candidates presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... Stimuvax Stimuvax is an investigational therapeutic cancer vaccine designed to induce an immune response to cancer cells that express MUC1, a glycoprotein antigen widely expressed on common cancers. MUC1 is over-expressed on many cancers such as lung cancer, breast cancer, prostate cancer and colorectal ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... combines a small peptide that activates the immune system with a small peptide from a disease-related protein, such as a herpes simplex virus (HSV) glycoprotein to make a vaccine that induces a defined immune response. Dr. Kenneth S. Rosenthal, Professor of Microbiology, Immunology and Biochemistry at ...

More>>

Glycoprotein in Biological Products

Glycoprotein Isolation Kit WGA from Pierce Biotechnology, Inc.

Description:... Biotechnology has developed two lectin based glycoprotein Isolation Kits, Concanavalin A (ConA) and Wheat ... acid. High recovery Equivalent or greater glycoprotein recovery versus competitor kits and lectin resins Fast glycoprotein purification in less than an hour Versatile ...
Company:Pierce Biotechnology, Inc.

Mouse Anti-Secretory Component Glycoprotein Monoclonal Antibody, Unconjugated, Clone SPM217 from Abcam

Description:... Mouse monoclonal [SPM217] to Secretory Component glycoprotein ( Abpromise for all tested ....
Company:Abcam

Anti-gp64 Antibody, Unconjugated from Novagen

Description:... The FastPlax Antibody is used to detect the appearance of AcNPV gp64 glycoprotein on the surface of infected cells as early as 8-24 hours post-infection. This forms the basis of the FastPlax Titer Kit, which allows determination of ...
Company:Novagen

Protein Blotting from Promega

Description:... such as radiometric and bioluminescence-enhanced detection systems are also included. Other topics covered are, the detection and characterization of glycoprotein carbohydrate chains and the study of DNA binding of immobilized ....
Company:Promega

Goat Anti-Human Alpha 1 Acid Glycoprotein Polyclonal Antibody, Unconjugated from Immunology Consultants Laboratory, Inc.

Description:... Goat anti-Human Alpha 1 Acid glycoprotein Preservative: 0.1% sodium azide Goats were immunized with highly purified human Alpha-1-acid glycoprotein in Freund's adjuvant. The antiserum was solid phase absorbed to ensure ...
Company:Immunology Consultants Laboratory, Inc.

Anti-P-selectin Glycoprotein Ligand-1 (PSGL-1) Monoclonal Antibody, Unconjugated, Clone KPL-1 from CHEMICON

Description:... Interactions between P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) mediate the earliest rolling of leukocytes on the lumenal surface of endothelial cells at sites of inflammation. To date, the ...
Company:CHEMICON

More>>

Glycoprotein in Biological Definition

Ebola

... consists of a central channel, 20-30 nm in diameter, surrounded by helically wound capsid with a diameter of 40-50 nm and an interval of 5 nm. 7 nm glycoprotein spikes that are 10 nm apart from each other are present within the outer envelope of the virus, which is derived from the host cell membrane. Each ...

Glycoprotein

... A glycoprotein is a macromolecule composed of a protein and a carbohydrate (a sugar ). The carbohydrate is usually attached to the protein in a ...

Immune system

... the immune system learning to recognize non-self. For instance, the plasma membrane of every nucleated cell contains molecules of a large glycoprotein called the major histocompatibility complex (MHC). These proteins have configurations and amino acid sequences that are unique to every ....

Monoclonal antibody

... this DNA and produce these half-mouse and half-human antibodies. (Bacteria cannot be used for this purpose, since they cannot produce this kind of glycoprotein ). Depending on how big a part of the mouse antibody is used, one talks about chimeric antibodies or humanized antibodies . Another approach ...

Blood type

... created against the bacteria will react to ABO-incompatible blood cells. Apart from on red blood cells, the ABO antigen is also expressed on the glycoprotein von Willebrand factor (vWF), which participates in hemostasis (control of bleeding). In fact, blood type O predisposes very slightly to ...

Zona pellucida

... The zona pellucida is a glycoprotein matrix surrounding the plasma membrane of a mammalian oocyte . This structure binds spermatozoa , and is required to initiate the acrosome ...

More>>

Glycoprotein in Biological Dictionary

Zona pellucida

... The zona pellucida is a glycoprotein membrane surrounding the plasma membrane of an ... the The zona pellucida is the spherical glycoprotein shell that sur ... caused by direct titration ... ZP2 gene (protein-coding), zona pellucida glycoprotein 2 (sperm receptor) ... Recommended Name: Zona ...

Glycoprotein

... glycoprotein IIb/IIIa, an integrin found on platelets that is required for ... Structure of glycoprotein and Carbohydrate Chain - Home Page for Learning ... P- glycoprotein is a well-characterized ABC-transporter of the ...

Oviduct

... dissected out on each ... Slide 10 Oviduct ... Oviduct -specific glycoprotein was long considered to be secreted specifically ... We found that oviduct -specific glycoprotein was expressed in the majority of ... ...

Transferrin receptor

... homeostasis. Transferrin is a blood plasma protein for iron ion delivery that, in humans, is encoded by the TF gene. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is ... Transferrin receptor transferrin receptor ...

Polyprotein

... during and after budding; this process is termed maturation. ... The European Bioinformatics Institute ... TLV/ENV coat polyprotein . Envelope glycoprotein precursor, Filoviridae type. Example proteins ... The European Bioinformatics Institute ... The regions of the polyprotein in which these ...

Plasma membrane

... mediated ... The plasma membrane is assymetric with respect to the lipid distribution. ... Plasma membranes also contain protein and glycoprotein in addition to lipid, of ... The plasma membrane is composed of a bilayer of phospholipid molecules, plus ... A cell membrane (also ...

More>>

Other Contents
(Date:8/1/2014)... A new study published in ... contribute to the development of colorectal cancer in patients ... study was authored by Alberto Martin of the University ... intestinal cells to multiply and create tumors in mice ... , “What’s interesting about this study,” said Shahab Mehdizadeh, ...
(Date:8/1/2014)... (PRWEB) August 01, 2014 Narconon Arrowhead ... the program at the drug rehab center located in ... year 2001, Narconon Arrowhead is the flagship drug rehab ... across the United States for services there. Now, with ... has recent outcome studies as well as client reviews ...
(Date:8/1/2014)... Albany, New York (PRWEB) August 01, 2014 ... intelligence firm, recently announced the addition of a ... The report, titled ‘Infusion System Market (Large Volume, ... Analysis, Size, Share, Growth, Trends And Forecast, 2013 ... the company’s website http://www.transparencymarketresearch.com . , To ...
(Date:8/1/2014)... By Tara Haelle ... -- A home-packed lunch isn,t necessarily healthier than school cafeteria ... that just 27 percent of the lunches third and fourth ... Lunch Program (NSLP) standards. , , "Our findings are similar ... across the world, which have found that high-calorie packaged foods ...
(Date:8/1/2014)... -- Although older women with asthma often have worse health ... to a new study. "There is no doubt that ... over 65," concluded Dr. James Sublett, an allergist and president-elect ... in an organization news release. In fact, the asthma ... nearly four times higher than in other groups of people, ...
Breaking Medicine News(10 mins):Health News:Carbs May Contribute to Colon Cancer 2Health News:Narconon Arrowhead Celebrates 4,300th Graduate from Program 2Health News:Narconon Arrowhead Celebrates 4,300th Graduate from Program 3Health News:Transparency Market Research Adds Report on Global Infusion System Market to its Repository 2Health News:Transparency Market Research Adds Report on Global Infusion System Market to its Repository 3Health News:Kids' Lunch Boxes Often Fall Short on Nutrition 2Health News:Kids' Lunch Boxes Often Fall Short on Nutrition 3Health News:Older Women With Asthma Face Worse Health Outcomes 2
(Date:7/31/2014)... By tracing nearly 3,000 genes to the earliest ... Florida scientists have created an extensive "Tree of ... next-generation DNA sequencing. , Among the study,s ... to small moths than to large ones, which ... The study also found that some insects once ...
(Date:7/31/2014)... (HPV-023; NCT00518336) shows the sustained efficacy, immunogenicity ... (HPV) vaccine Cervarix. Women vaccinated with the ... than nine years, and vaccine efficacy (VE) ... the longest follow-up report for a licensed ... the full paper. , HPV and ...
(Date:7/31/2014)... German . ... to a sponge that soaks up liquids. Hence, these ... greenhouse gases. However, loading of many MOFs is inhibited ... now report in Nature Communications that the ... This can be prevented by water-free synthesis and storing ...
Breaking Biology News(10 mins):UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 2Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 3Free pores for molecule transport 2
Other TagsOther Tags