JCI online early table of contents: Feb. 16, 2009
... antibodies to cause neuropathy has been so hotly debated.
TITLE: The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid
environment in mice
Hugh J. Willison
University of Glasgow, Glasgow, United Kingdom.
Phone: 44-141-330-8384; Fax: ...
Also in the Nov. 11 JNCI
... receptor 2 or 3 form larger and more aggressive tumors in xenograft mouse models than controls cells that do not express the receptors.
LPA is a glycolipid
that stimulates DNA synthesis, proliferation, survival, migration, and cytokine production in cells when it binds to cell-surface receptors called ...
Autoimmune Diseases – Newer Preventive Measure
... or worsen an autoimmune disease by producing good or bad cytokines. That’s why it also has worked for some cancers and why a modified version of the glycolipid
or totally different drugs may work better, Dr. She says. ‘By understanding more, we are better able to come up with better targets,’ he says. ...
Glycolipid in Medical Technology
Micromet Key Events for 2009
... the treatment of chronic inflammatory and autoimmune
diseases, is expected to start a first clinical phase 1 trial in mid 2009;
-- MT228, a glycolipid
binding human antibody in development by Eisai for
the treatment of melanoma, is expected to start a first phase 1 clinical trial
Glycolipid in Medical Products
Anti-Myelin Associated Glycoproteins (MAG) Western Blot
Description:... A Western Blot Immunassay for the detection of antibodies to primarily anti-myelin associated glycoproteins (anti-MAG) and other glycolipid
autoantibodies in human ....
Anti-Myelin Associated Glycoproteins (MAG) IFA
Description:... For the screening and detection by indirect immunofluorescence (IF) of primarily anti-myelin associated glycoproteins (anti-MAG) and other glycolipid
autoantibodies in human ....
Glycolipid in Biological News
UCSD discovery may help extend life of natural pesticide
... that the defective sugar structure of the glycolipid
receptor in each of the mutants prevents Bt from ... determined the chemical structure of the normal glycolipid
receptor that binds Bt toxin.
Elements of this ... at the University of Georgia, showed that the glycolipid
receptor is present in the tobacco hornworm, an ...
New pathways for autoimmune treatment identified
... or worsen an autoimmune disease by producing good or bad cytokines. That's why it also has worked for some cancers and why a modified version of the glycolipid
or totally different drugs may work better, Dr. She says. "By understanding more, we are better able to come up with better targets," he says.
Scientists solve structure of key protein in innate immune response
The innate immune system uses the CD14 receptor protein to recognize several microbial and cellular products including lipopolysaccharide (LPS), a glycolipid
found on the outer membrane of certain bacteria. Once CD14 binds to LPS or another ligand, it presents the molecule to other proteins which initiate ...
Glycolipid in Biological Dictionary
... ... an incomplete listing of glycolipid
types. ... Metabolism: lipid metabolism · glycolipid
enzymes. Sphingolipid. To ... "http://en.wikipedia.org /wiki/ glycolipid
" ... any member of a group of ...