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Glycogen in Medical News

Glucose metabolism and recidivism of severe violent crimes in alcohol intoxications

... crimes. A Finnish study now finds that low glycogen level which means non-oxidative glucose ... deviations lower than non-recidivistic offenders. glycogen levels did not differ among nonrecidivists and 40 ... in alcohol intoxications when they have very low glycogen stores in the liver. The low activity of the ...

Gene therapy could save kids from a lifetime of eating cornstarch

... People born with the disorder, called glycogen storage disease type Ia (GSD-Ia), cant make an ... Fund for GSD Research, the Association for glycogen Storage Disease and the Duke Childrens Miracle ... dogs with a naturally-occurring canine form of glycogen storage disease. The original genetic carrier, a ...

Hydration Will Be Key For Beijing Bound Olympians, What Every Athlete Must Know

... For two hours after severe exercise, the ingested sugar is moved back into glycogen without insulin. By having more concentrated sugar concentrations in the drink, the glycogen restoration is helped. Athletes should pay close attention to the ...

Austin Company Makes a Splash at U.S. Olympic Team Swimming Trials

... minutes of completing a workout to speed the storage of muscle and liver glycogen and promote muscle tissue repair. "When you exercise," says Ivy, "the ... minutes of completing a workout to speed the storage of muscle and liver glycogen and promote muscle tissue repair. Among the athletes and coaches who ...

BioMarin Announces Second Quarter 2009 Financial Results

... is a highly phosphorylated GAA enzyme, which the company believes could result in more efficient uptake in cells and potentially lead to improved glycogen reduction in key affected muscle groups not addressed with current therapy. BioMarin continues to explore partnering options for this program. ...

Transplanted liver cells function in older animals but do not proliferate as much as in younger ones

... that seen in younger ones. Furthermore, found the scientists, the transplanted cells worked equally well in the old and young animals, as measured by glycogen storage, but the younger animals had significantly higher levels of a growth factor needed for proliferation. The new study is the first to offer ...

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Glycogen in Medical Technology

Amicus Therapeutics Suspends Enrollment for Phase 2 Clinical Trial of AT2220 for Pompe Disease

... The study will also explore certain pharmacodynamic and pharmacokinetic measures including the effect of treatment with AT2220 on GAA activity and on glycogen levels in various cells and tissues. Additional objectives include preliminary assessments of pulmonary and skeletal muscle function. Participants ...

Amicus Therapeutics Begins Phase 2 Clinical Trial of AT2220 in Pompe Disease

... study will also explore certain pharmacodynamic and pharmacokinetic measures including the effect of treatment with AT2220 on GAA activity and on glycogen levels in various cells and tissues. Additional objectives include preliminary assessments of pulmonary and skeletal muscle function. Participants ...

Go Healthy Initiates Additional Clinical Tests on Cholesterade

... the Ohio State University and Duke University. Future centers will be coordinated by CO-PIs, Dr. Hal Goforth, widely acclaimed researcher on muscle glycogen metabolism from Point Loma Nazarene University and the Naval Research Center, and Dr. Fran Pirozzolo, Chairman of the Medical and Scientific Advisory ...

Amicus Therapeutics Announces Positive Results From Two Phase 1 Clinical Studies of AT2220 for Pompe Disease

... selectively bind to and stabilize acid a-glucosidase (GAA), the enzyme deficient in Pompe disease. This deficiency leads to lysosomal accumulation of glycogen inside muscle cells, which is believed to cause the various symptoms of Pompe disease. AT2220 facilitates proper trafficking of the enzyme to the ...
Glycogen in Medical Products

Insulin RIA Test

Description:... receptors [3] and facilitates substrate uptake and intracellular utilization, resulting in net increases in intracellular lipid, protein and glycogen [1,2,3,4]. Insulin is rapidly cleared both by liver uptake, tissue utilization and renal clearance and circulating insulin levels are very low during ...
Company:Diagnostic Systems Laboratories, Inc.
Glycogen in Medical Definition

Pathology

... aciduria , Citrullinemia , Hyperammonemia ) - Glutaric acidemia type 1 - Sarcosinemia Carbohydrate Lactose intolerance - glycogen storage disease ( type I , type II , type III , type IV , type V , type VI , type VII ) - Fructose intolerance - Essential fructosuria - ...
Glycogen in Medical Dictionary

Death

... ... Call your health care provider if there is a family history of glycogen storage disease or early infant death due to low blood sugar . Genetic counseling is recommended if there is a family history of glycogen storage disease . Prevention ... massive can lead to , , and even ...

Disease

... is a group of inherited metabolic disorders that involve increased glycogen storage. Since glycogen is needed to fuel muscle s, problems with its metabolism can affect the ...

Glucose

... s in the form of glycogen. You can only work as long as you have stored glycogen ready to be changed into glucose . glucose Dextrose . A simple ... in an inability to metabolize glucose , and the capacity to store glycogen (a form of glucose ) in the liver and the active transport of glucose ...

Vasodilation

... if no medical help is available. Epinephrine causes a breakdown of glycogen to glucose in liver and muscle , the release of fatty acids from ... acronym for vasodilation in ... Epinephrine causes a breakdown of glycogen to glucose in the liver , encourages the release of fatty acids from ...

Alpha1-antitrypsin deficiency

... ... Other genetic conditions associated with liver cancer include several inborn errors of metabolism such as tyrosinemia , glycogen storage disease type I, galactosemia , and alpha1-antitrypsin deficiency . ...

Amylase

... the amount of this enzyme in a sample of blood taken from a vein or in a sample of urine . Amylase is an enzyme that helps digest glycogen and starch. It is produced mainly in the salivary gland s and pancreas . When the pancreas is disease d or inflamed, amylase escapes into the ...

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Glycogen in Biological News

UF makes gene therapy advance in severe genetic disorder

... a cure for the disorder in children. Called glycogen storage disease type 1A, the genetic disease ... Weinstein, M.D., M.M.Sc., director of the UF glycogen Storage Disease Program and co-investigator on ... one in 100,000 children have this severe form of glycogen storage disease. Children receive doses of ...

Post-exercise caffeine helps muscles refuel

... ingested caffeine with carbohydrate had 66% more glycogen in their muscles four hours after finishing ... Society. The study, "High rates of muscle glycogen resynthesis after exhaustive exercise when ... bout was designed to reduce the athletes' muscle glycogen stores prior to the experimental trial the next ...

The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases

... this disease arises. Joan J. Guinovart, expert in glycogen metabolism explains, We have observed that laforin and malin act jointly as guardians of glycogen levels in neurons and are stimulated by the ... its function, these proteins are not degraded, glycogen accumulates and thus neurons deteriorate and cell ...

Computational model examines the pathways of Alzheimer's that strikes at the young

... the study entitled A Computational Model of the Role of Presenilin-1 and glycogen Synthase Kinase-3 in Familial Alzheimer's Disease. They will present their ... The proteins presenilin-1 (PS1) (a mutated gene found in familial AD) and glycogen synthase kinase (GSK-3) (a protein) and amyloid beta (Aβ) plaque ...

Computational model examines the pathways of Alzheimer's that strikes at the young

... the study entitled A Computational Model of the Role of Presenilin-1 and glycogen Synthase Kinase-3 in Familial Alzheimer's Disease. They will present their ... The proteins presenilin-1 (PS1) (a mutated gene found in familial AD) and glycogen synthase kinase (GSK-3) (a protein) and amyloid beta (Aβ) plaque ...

Single-celled bacterium works 24-7

... atmosphere, and water, Cyanothece produces glucose, a sugar it stores in glycogen granules, filling its chemical gas tank. At night, the Cyanothece ramps up ... Since nitrogen fixation requires a lot of energy, Cyanothece uses the glycogen stored in its chemical gas tank through a process called respiration. ...

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Glycogen in Biological Technology

BioMarin Announces First Quarter 2009 Financial Results

... is a highly phosphorylated GAA enzyme, which the company believes could result in more efficient uptake in cells and potentially lead to improved glycogen reduction in key affected muscle groups not addressed with current therapy. BMN-168 - 6R-BH4 Prodrug: BioMarin is proceeding with important ...

Catalyst Biosciences Expands Scientific Advisory Board With Leading Experts in Protease Therapeutic Discovery and Development

... Among a total of approximately three hundred scientific papers, he has published 50 manuscripts on protease structure and function. His work on glycogen phosphorylase revealed the first mechanism of phosphorylation control of protein function. Professor Fletterick's laboratory solved the first ...

High Electrotransformation Efficiencies Obtained With DNA From Ligation Mixtures

... with a 0.1 volume of 3 M sodium acetate, 20 g of glycogen (except where noted), and 2.5 volumes ... ligation mixture in the presence of glycogen achieved nearly the same high ... the control supercoiled pUC18 plasmid (Figure 1). glycogen was used as a carrier to reduce the ...

Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock Gel-Heavy

... 0.8 ml TRIzol Reagent and 0.2 ml 1 mg/ml mussel glycogen and homogenize. ... and 0.2 ml 1 mg/ml mussel glycogen and homogenize. Cells grown in ... ml TRIzol Reagent and 0.2 ml 1 mg/ml mussel glycogen and homogenize. ...

Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock Gel-Heavy

... 0.8 ml TRIzol Reagent and 0.2 ml 1 mg/ml mussel glycogen and homogenize. ... and 0.2 ml 1 mg/ml mussel glycogen and homogenize. Cells grown in ... ml TRIzol Reagent and 0.2 ml 1 mg/ml mussel glycogen and homogenize. ...

Rapid, Reproducible Real-Time Quantitative RT-PCR Using the iCycler iQ Real-Time PCR Detection System and iQ Supermix, Rev A

... and the midperiphery, using Trizol reagent (Invitrogen) with glycogen added as a carrier as described by Bracete et al. (1999) with the following modification: 0.9 ml Trizol reagent plus 13.5 l glycogen (20 mg/ml, Roche Molecular Biochemicals) was added to ...

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Glycogen in Biological Products

PPase-2A from Promega

Description:... subunit, PPase-2A has broad substrate specificity and may play a regulatory role in DNA replication, transcription, protein synthesis, mitosis and glycogen metabolism. PPase-2A is stimulated in vitro by basic proteins such as protamine, histones and polylysine. The enzyme is inhibited by several ...
Company:Promega
Glycogen in Biological Definition

Diabetes mellitus

... of glucose (the basic sugar unit) to glycogen for storage in liver and muscle cells. Lowered insulin levels result in the reverse conversion of glycogen to glucose when glucose levels fall -- though ... the liver to convert its internal stores of glycogen to be released as glucose into the blood. Oral or ...

Glucose

... form sucrose . Starch , cellulose , and glycogen are common glucose polymers ( polysaccharides ... liver and skeletal muscle by the breakdown of glycogen stores (glucose polymers ). Synthesized in ... the liver and muscles , where it is stored as glycogen ("animal starch"), and to fat cells , where it ...

Insulin

... of insulin on cells include: increased glycogen synthesis – insulin forces storage of ... levels of insulin cause liver cells to convert glycogen to glucose and excrete it into the blood. This is ... causes glucose absorption and storage, reducing glycogen to glucose conversion, reducing blood glucose ...

Liver

... functions in the body including detoxification, glycogen storage and plasma protein synthesis. It also ... Glycogenolysis (the formation of glucose from glycogen ) Glycogenesis (the formation of glycogen from glucose) The breakdown of insulin and ...

Polysaccharide

... storage polysaccharides such as starch and glycogen and structural polysaccharides such as ... 1 Starches 2 glycogen 3 Cellulose 4 Acidic polysaccharides ... major sources of starch in the human diet. glycogen ...

Cellular respiration

... 4 H + The individual steps of the conversion of glucose into pyruvate are (in brief): A glucose molecule from the hydrolysation of starch or glycogen is phosphorylated using one ATP molecule to give glucose-6-phosphate. The glucose-6-phosphate is converted to fructose-6-phosphate by ....

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Glycogen in Biological Dictionary

Glycogen

... glycogen is the molecule which functions as the ... glycogenesis within the brain and ... glycogen n. A polysaccharide, (C 6 H 10 O 5 ) n , that is ... and occurs primarily in the liver and glycogen phosphorylase This article needs additional ...

Polysaccharides

... billions of web pages to find the ... A look at the structural polysaccharides ; cellulose and chitin and the storage polysaccharides ; glycogen and starch. ... Polysaccharides are the complex ... Ah, the sweet taste of sugar. Most of us love and adore its taste. ... Some examples of ...

Glycolysis

... ... The glycolysis page describes the process and regulation of glucose breakdown ... Entry of Non-Glucose Carbons into Glycolysis . glycogen Metabolism ... This process is known as glycolysis . Glycolysis takes place in the cytoplasm and can occur without the presence of ... ...

Glucagon

... Produced by the pancreas, it is released when the glucose level in the blood is low (hypoglycemia), causing the liver to convert stored glycogen ... Glucagon rescue is the emergency injection of glucagon in case of severe diabetic hypoglycemia. It is needed during seizures and/or ...

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