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Glial in Medical News

CU-Boulder study shows brain's immune system may cause chronic seizures

... role in seizures. Researchers have found that glial cells, which are supportive cells that also ... the damage and repair it," Barth said. "These glial cells migrate to the damaged area and release ... our new study, we showed for the first time that glial cells moving in and secreting these cytokines ...

Team led by Scripps Scientists increases understanding of two types of blindness

... Eye neurons are supported and nourished by glial cells, which surround them. One type of these ... the front to the back of the retina and produce glial fibrillary acidic protein (GFAP) in response to a ... These viral particles crossed into the Mller glial cells, which allowed neurotrophin 4 protein ...

Neurogenesis in the adult brain: The association with stress and depression

... 1). In addition, there is a reduced density of glial support cells that are instrumental in the ... also induce changes in the formation of specific glial support cells (=gliogenesis) that are critical ... in the brain. There are about 100 times more glial cells than nerve cells, providing energy and ...

New regulatory circuit identified for aggressive, malignant brain tumor

... of p18INK4C in p16INK4A-deficient primary glial cells or established GBM cells enhanced ... while acute suppression of p16INK4A in primary glial cells induced an increase in p18INK4C. These ... INK4 family members to constrain inappropriate glial cell proliferation, concludes Dr. Chin. This ...

Key factor in brain development revealed, offers insight into disorder

... immature cells, produced from so-called radial glial progenitor cells which in turn evolve from ... division and proliferation processes in radial glial progenitor cells. However, scientists have not ... not essential, for cell division in the radial glial progenitor cells. Lis 1, they showed, plays a ...

Post brain injury: New nerve cells originate from neural stem cells

... to the brain. However, what these reactive glial cells in the brains of mice and men originate ... is able to show that after injury, these reactive glial cells in the brains of mice restart their cell ... cortex. Gtz proved in earlier investigations that glial brain cells can act as stem cells, and nerve ...

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Glial in Medical Technology

Solace Pharmaceuticals Initiates Phase IIa Trial of Glial Cell Modulator SLC022 in Post-Herpetic Neuralgia

... of 2009. SLC022 is an orally administered glial cell modulator that has shown efficacy in well-established preclinical pain models. glial cells represent an important new target for the ... progress. In 2008, Solace expanded its glial cell modulator program by ...

Astrocytes Help Separate Man From Mouse

... added Nedergaard, who spoke last week at a Gordon Research Conference on glial biology. "Studies in rodents show that non-neuronal cells are part of ... using different languages," said Nedergaard, director of the Division of glial Disease and Therapeutics of the Center for Translational Neuromedicine. ...

Headache Specialists Convene in Boston For 50th Annual American Headache Society Meeting

... neurons are not the only carrier of pain signals to the brain. glial cells, which outnumber neurons 20:1, have been shown to prompt ... damage or even medication. Morphine and other opiates also activate glial cells, which mean those drugs you're taking to alleviate pain might ...

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

... can significantly reduce this death in an animal model of retinal detachment. In addition, we show that Palomid 529 also reduces the activation of glial cells and subsequently slows the formation of subretinal scar tissue, a condition that can prevent the regeneration of photoreceptors following ...

Groundbreaking Paper Publishes Long Term Results of a Successful Phase I Clinical Trial Using Autologous Neural Stem Cells to Treat Parkinson's Disease

... This suggests that in humans, Parkinson's disease is more than a chronic dopaminergic dysfunction and involves the GABA-ergic system with its glial environment. The relevance of this discovery cannot be understated because it questions the classical dopaminergic model of Parkinson's disease," ...

Expert Opinion Highlights Avigen's AV411 as Potential New Therapeutic for Neuropathic Pain and Opioid Withdrawal

... with diabetic neuropathic pain, modulates glial cell function, an important contributor to ... unique properties, AV411 attenuates or suppresses glial cell activation in brain and spinal cord tissues ... research adds to the increasing recognition of glial attenuation as a potential new paradigm shift in ...
Glial in Medical Definition

Ramón Carrillo

... and neurobiology Between 1930 and 1945 he contributed valuable original research about the brain cells which are not neurons—named glial cells —and the method for staining and observing them under the microscope , as well as on their evolutionary origin ( phylogeny ), and the ...
Glial in Medical Dictionary

Gliomas

... Gliomas are tumor s that most commonly arise from a specific type of glial (supportive tissue ) cell known as an astrocyte. Astrocytes make up ... eyes ) or the optic chiasm. Gliomas are thought to be derived from glial cells such as astrocytes, oligodendrocytes, and ependymal cells. These ...

Medulla

... arising from a type of cell of the central nervous system known as a glial cell . These tumor s originate from a specific type of glial cell known as an astrocyte. Medulla ry thyroid cancer This type of ...

IV

... a different influence on pain , disturbed sleep or tender point count. METHODS: ... grade IV astrocytoma A type of brain tumor that forms from glial (supportive) tissue of the brain. It grows very quickly and has cells that look very different from normal cells. Also called gliobla stoma multi ...

Keratin

... skin . Also found to a lesser degree on the surface of monocyte s / macrophage s , Langerhans cells , astrocytes, keratin ocytes and glial cells. HIV invades cells by attaching itself to the CD4 molecule (CD4 receptor). euglobulin clot lysis time; euglycaemia; euglycaemic; ...
Glial in Biological News

Work in mice will contribute to the study of hereditary diseases that lead to blindness

... scientific meetings: VIII European Meeting on glial Cell Functions in Health and Disease (Londres), VII European Meeting on glial Cell Functions in Health and Disease (Amsterdam), IV Meeting of the Spanish glial Network (Madrid), etc. ...

Cell's split personality is a major discovery into neurological diseases

... cell death involves another vital player namely, glial cells," says Dr. Adriana Di Polo, neuroscientist ... that glutamate activates signaling pathways in glial cells that then lead to neuronal death." glial cells are the most abundant cell type in the ...

Rett Syndrome Research Trust advisor makes significant discovery

... and the ongoing struggles to address them. glial cells, which reside throughout the nervous ... protective insulation for axons. These and other glial functions are essential to the health of neurons. ... study adds to the growing body of evidence that glial cells are critically important contributors to ...

Resuscitation technique after brain injury may do more harm than good

... Kernie said. Myelin comes from cells called glial cells, or glia, which reach out and wrap part of ... The brain creates and renews its population of glial cells from a pool of immature cells that can ... cerebral palsy. The population of immature glial cells also diminished, suggesting that the ...

Veterinary college researcher studying brain tumors in people and animals

... and other problems. Gliomas arise from glial cells, according to Rossmeisl, which play ... that control thought, sensations and motion. glial cells outnumber neurons by a factor of about ten ... There are several different specific types of glial cells, but two that interest Rossmeisl and ...

Swamping bad cells with good in ALS animal models helps sustain breathing

... decline." Also significant is that the transplanted cells, called glial restricted precursors (GRPs), address a well-known flaw in people with ALS ... nervous system. In their research, the team transplanted some 900,000 glial restricted precursors overall to specific sites in the cervical spinal ...

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Glial in Biological Technology

Solace Pharmaceuticals Appoints Professor David Julius, Renowned Pain Physiologist, to Scientific Advisory Board

... to those of Solace, especially with respect to his recent work in glial cells, and we share his dedication to transforming biological insights ... disease-modifying potential in two key areas: modulating the activity of glial cells and intervening in the tetrohydrobiopterin (BH4) pathway. SLC022, ...

Ceregene Receives Additional Grant From Michael J. Fox Foundation to Expand Long-Term Testing of CERE-120 Patients

... damaged and dying dopamine-secreting neurons, keeping them alive and restoring normal function. Neurturin is a member of the same protein family as glial cell-derived neurotrophic factor (GDNF). The two molecules have similar pharmacological properties, and both have been shown to benefit the midbrain ...

Effectene Transfection Reagent provides efficient gene delivery to primary neuronal cell cultures

... a confluent layer of collicular glial cells and were cultured for up to 3 weeks. On the ... cytosine arabinoside (4 M) was added to inhibit glial cell proliferation. Transfection was ... containing the neurons were removed from the glial cell culture and placed cell-side up in ...

Efficient DNA transfection of primary CNS neurons using TransMessenger Transfection Reagent

... www.qbmcellscience.com ), which contain a mixture of neuronal and glial cells. The cultured cells expressed characteristic markers and ... for neurons, anti-GFAP antibodies for astrocytes, the major subtype of glial cells in the brain). " Excellent Morphology of CryoCell ...

UW-Madison rat experiment could lead to stem-cell treatment for ALS

... not only replace damaged cells but help protect existing motor neurons. The protein that actually protects the motor neurons is called GDNF, for glial cell-line derived neurotrophic factor. "The approach we're taking is a protective approach versus a cell-replacement approach," said Sandra Klein, ...

Stem cells produce anti-disease protein in brain experiment

... the bodys movement, to recover from the damage caused by disease. The study involved use of a naturally occurring protein in the brain called glial cell-derived neurotrophic factor, or GDNF, which has been found to help the brain keep generating dopamine. Experimental evidence in both animals and ...

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Glial in Biological Products

NeuroCyte - Rat Neural Stem Cell Kit from Orion BioSolutions, Inc.

Description:... a unique mix of nestin expressing neuroepithelial stem cells and radial glial cell-like neuroglial progenitors, which retain the capacity for ... neuroepithelial sheets provide an anchor for directed radial glial cell process extension and subsequent neuroglial progenitor and neuroblast ...
Company:Orion BioSolutions, Inc.

rNeural Stem Cell (rNSC)Kit from AlphaGenix, Inc.

Description:... Rat neural stem cell kits are intended for the in vitro growth and commitment to neuronal and glial lineage differentiation, of cultured fetal rat neural stem and progenitor cells expanded using ....
Company:AlphaGenix, Inc.

Human Neural Stem Cell Functional Identification Kit from R&D Systems

Description:... the induction of NSCs into astrocyte, neuron and oligodendrocyte lineages. An antibody panel consisting of mouse anti-human Nestin, mouse anti-human glial Fibrillary Acidic Protein (GFAP), mouse anti-Neuron-specific beta-III Tubulin, and mouse anti-Oligodendrocyte Marker O4 are also included to identify ...
Company:R&D Systems

Mouse/Rat Neural Stem Cell Functional Identification Kit from R&D Systems

Description:... differentiation of NSCs into astrocyte, neuron and oligodendrocyte lineages. An antibody panel consisting of goat anti-rat Nestin, sheep anti-human glial Fibrillary Acidic Protein (GFAP), mouse anti-Neuron-specific beta-III Tubulin, and mouse anti-Oligodendrocyte Marker O4 are also included to identify ...
Company:R&D Systems

Immunodetection of Specific Proteins from QualTek Molecular Laboratories

Description:... Animals Hundreds of Specialty Markers, Including: Vector Detection with - Galactosidase Proliferation Markers - PCNA, Brdu, Ki67 Neural and glial Markers Apoptosis Related Proteins Visualization of Low Expresser ...
Company:QualTek Molecular Laboratories

Neural Stem Cell Expansion Kit - Monolayer from R&D Systems

Description:... the antibodies Tuj1, O4 and anti-GFAP, respectively. Neural stem cells (NSCs), with the potential to self-renew and to differentiate into neurons and glial cells, have been isolated from different regions of the developing and adult brain (1 - 6). NSCs can be grown in vitro , in the presence of mitogen, ...
Company:R&D Systems

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Glial in Biological Definition

Neuron

... axons of the same diameter. Formed by glial cells in the central nervous system and Schwann ... the central nervous system. There are far more glial cells than neurons, and recent experimental results have suggested that glial cells play a vital role in information processing ...

Axon

... or even longer. In vertebrates generally, the axons of many neurons are sheathed in myelin , which is formed by either of two types of glial cells : Schwann cells ensheathing peripheral neurons and oligodendrocytes insulating those of the central nervous system . Along myelinated ...

Intermediate filament

... some organelles in a fixed place within the cytoplasm . Peripherin found in peripheral neurons. GFAP (glial fibrillary acidic protein) in glial cells . Neurofilaments These are found in nerve cells and are implicated in the radial growth of the axon . α-Internexin ...

Ion channel

... manner. They are involved in important physiological processes such as the pacemaker activity in the heart, insulin release, and potassium uptake in glial cells. Certain channels respond to multiple influences. For instance, the NMDA receptor is partially activated by interaction with its ligand, ...
Glial in Biological Dictionary

Neuroglia

... glial cells, commonly called neuroglia or simply ... in the free online English dictionary and ... glial cell, neurogliacyte, neuroglial cell - a cell ... n. See neuroglia . [Short for NEUROGLIA .] glial gli ' al adj. ... Neuroglia ; the supporting ...

Glial cells

... glial cells , commonly called neuroglia or simply ... in the nervous system. In the ... glial cells , commonly called neuroglia or simply ... are one of two major ... In the mammalian brain, glial cells are estimated to outnumber neurons by ...

Schwann cells

... physiologist Theodor Schwann , Schwann cells are a variety of glial cell that keep peripheral nerve fibres alive. In myelinated axons, ... This report shows that Schwann cells respond to recombinant human glial Growth ... ...

Proto-oncogene

... high levels, helps turn a normal cell into a cancer cell. The RET proto - oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor family of extracellular signalling molecules. RET loss of function mutations are associated with ... ....

Myelin sheath

... sheath , usually around only the axon of a neuron. It is essential for the proper functioning of the nervous system. Myelin is an outgrowth glial cell: ... Supports research on myelin repair after it has been destroyed by hereditary disorders such as the leukodystrophies or ... ...

Myelin

... sheath, usually around only the axon of a neuron. It is essential for the proper functioning of the nervous system. Myelin is an outgrowth glial cell: ... myelin also myeline ( ) n. A white fatty material, composed chiefly of lipids and lipoproteins, that encloses certain axons ...

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