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gene in Medical News

Many Opt for Surgery to Lower Breast, Ovarian Cancer Risk

... Women with BRCA gene mutations often choose preventive measures, study ... 211 women, aged 35 to 45, with BRCA1 or BRCA2 gene mutations, which are known to increase the risk ... Forty percent of women with BRCA1 and BRCA2 gene mutations had both breasts removed and 45 percent ...

Carnegie Mellon develops innovative method to detect genetic causes of complex diseases

... method showed increased power in detecting gene variants associated with complex symptoms ... In one test, GFlasso successfully detected a gene variant already implicated in severe asthma and ... metrics and family history, and that genome-wide gene expression profiling can identify tens of ...

Abnormal Brain Circuits May Prevent Movement Disorder

... scans who had no disease and no mutations in the gene for dystonia. Dr. Eidelberg and his ... that patients and non-patients with the disease gene have the same underlying functional brain ... approximately 30% of people who carry the mutated gene called DYT1 will develop the involuntary ...

Genes key to staph disease severity, drug resistance found hitchhiking together

... for disease severity. They also found the gene for the toxin traveling with a genetic component ... become drug-resistant is through horizontal gene transfer, whereby resistance genes move from one ... location that encodes the toxin, which was in gene clusters that control drug resistance, known as ...

UF scientists program blood stem cells to become vision cells

... this is the first report using targeted gene manipulation to specifically program an adult ... describe how they used a virus carrying a gene that gently pushed cultured adult stem cells from ... process, scientists were able to bypass the gene manipulation step entirely and instead use ...

Gene Found for Age-Related Cataract

... FRIDAY, July 31 (HealthDay News) -- A gene associated with the formation of age-related ... has been identified by scientists. The EphA2 gene encodes an enzyme that plays a role in the repair ... proteins in the eye. Expression of the EphA2 gene decreases with age, which means damaged proteins ...

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gene in Medical Technology

Diabetes Gene Raises Odds of Lower Birth Weight

... -- Pediatric researchers have found that a gene previously shown to be involved in the ... Diabetes . "It's a bit unusual to find a gene linked to both prenatal events and to a disease ... of The Children's Hospital of Philadelphia. "This gene variant carries a double whammy, in raising the ...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... ZFNs to generate rats with permanent, heritable gene mutations, paving the way for the development of ... used ZFNs to knock out an inserted reporter gene and two native rat genes without causing ... This is the first example of successful gene editing in mammalian embryos using this ...

Mayo Clinic Study Finds Earliest Evidence of Memory Decline in Middle-Aged People at Genetic Risk for Alzheimer's Disease

... at older ages. Each additional copy of this gene is associated with a higher risk of Alzheimer's ... appears to decline more quickly in APOE e4 gene carriers, and it is this pattern of cognitive ... in cognitively normal carriers of the APOE e4 gene to evaluate promising Alzheimer's prevention ...

Fruitfly Model of a Neuropathic Disease Demonstrates Novel Role for Proteins in the Family of aTyr Pharma's Product Class

... that some CMT patients have mutations in a gene encoding tyrosyl-tRNA synthetase. While tRNA ... understand how mutations in the tRNA synthetase gene disrupt the neurological system of a complex ... this fruit fly model, the tyrosyl-tRNA synthetase gene encodes a distinct function involved in the ...

Sangamo BioSciences Announces Achievement of Key Milestone in Cell Engineering Agreement With Genentech

... protein (ZFP) technology for therapeutic gene regulation and modification. By engineering ZFPs ... factors (ZFP TF(TM)) that can control gene expression and, consequently, cell function. ... sequence-specific ZFP Nucleases (ZFN(TM)) for gene modification. The most advanced ZFP ...

More Gene Mutations Linked to Autism Risk

... and deletions is thought to interfere with gene function, which can disrupt the production of ... He added that the team discovered many "private" gene mutations, those found only in one or a few ... of genetic complexity, in which many different gene changes may contribute to an autism spectrum ...

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gene in Medical Products

HER2 FISH pharmDx Kit

Description:... assay designed to quantitatively determine HER2 gene amplification in formalin-fixed, paraffin-embedded breast cancer tissue specimens. gene amplification is determined from the ratio ... of signals from the hybridization of the HER2 gene probe (red signals) and the number of signals ...
Company:DakoCytomation California Inc.

hGH ELISA

Description:... by cells of the anterior pituitary. The hGH gene contains five exons and is the best characterized of five members of a gene family. The hGH ELISA is used to quantitatively ... transfected with a plasmid containing a reporter gene encoding for hGH. hGH Elisa is standardized, ...
Company:Roche Diagnostics

Gene Cycler Thermal Cycler

Description:... The gene Cycler unit is an inexpensive personal or mini ... including the researcher's desk. The gene Cycler thermal cycler meets the needs of ... expensive laboratory thermal cycler. The gene Cycler is an advanced solid-state thermal cycler ...
Company:Bio-Rad Laboratories

Leptin IRMA Test

Description:... with a molecular weight of 16 kDa. Leptin is a protein encoded by the ob gene and produced by adipocytes [1,2]. Leptin is thought to play a key role in ... Metab. 82. 3281, 1997 Pelleymounter, MA, et al.: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543, ...
Company:Diagnostic Systems Laboratories, Inc.

Leptin ELISA Test

Description:... with a molecular weight of 16 kDa. Leptin is a protein encoded by the ob gene and produced by adipocytes [1,2]. Leptin is thought to play a key role in ... Metab. 82. 3281, 1997 Pelleymounter, MA, et al.: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543, ...
Company:Diagnostic Systems Laboratories, Inc.

HSV Typing ASR

Description:... ASR contains primers and a FAM-labeled probe targeting the glycoprotein D gene of HSV Type 1 as well as primers and an Alexa 532-labeled probe designed to detect the glycoprotein G gene of HSV Type 2. This ASR requires an instrument that can detect FAM, Texas ...
Company:Cepheid

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gene in Medical Definition

Personalized medicine

... about a patient's genotype or level of gene expression and a patient's clinical data in ... history. The key task is to find genes and gene variations that play a role in a disease. The ... is to associate the occurrence of a particualr gene variant with the incidence of a particular ...

Therapeutic gene modulation

... Therapeutic gene modulation refers the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in ...

Thymocyte

... defects introduced into the T cell receptor by gene rearrangement. In order to be ... receptor is made up of a series of alternative gene fragments. In order to create a functional T cell ... enzymes to clip the DNA and bring separate gene fragments together. The outcome of this process ...

Atransferrinemia

... inherited in an autosomal recessive pattern, meaning two copies of the gene in each cell are altered. A case study was done in 1961 on a ... in the United States [2] and identified mutations in the TF gene as a probable cause of the disorder. Treatment Treatment with ...

Autoimmune regulator

... q22.3 The Autoimmune Regulator, abbreviated AIRE , is a human gene which is expressed in the thymus . It causes transcription of a wide ... candidiasis. [1] AIRE is expressed primarily in the thymus. A gene knockout of the murine homolog Aire has created a transgenic mouse ...

Familial isolated vitamin e deficiency

... is a rare autosomal recessive neurodegenerative disease. Symptoms are much like those of Friedreich ataxia and is caused by mutations in the gene for a-tocopherol transfer protein. ...

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gene in Medical Dictionary

Adenoviruses

... and eye infections . Adenoviruses used in gene therapy are altered to carry a specific tumor -fighting gene . adjunct agent In cancer therapy, a drug or ... effects are short-lived. Maintaining gene expression so it performs its role properly ...

Adenovirus

... and eye infections . Adenovirus es used in gene therapy are altered to carry a specific tumor -fighting gene . adjunct agent ... Adenovirus EIA test kit ... effects are short-lived. Maintaining gene expression so it performs its role properly ...

Alkaptonuria

... Among the genes on chromosome 3 are the HGD gene for alkaptonuria , the BTD gene for biotinidase deficiency , the CPOX gene for hereditary copro porphyria , the MLH1 ...

Autosomal dominant

... dominant Definition: A single, abnormal gene on one of the autosomal chromosomes (one of ... Autosomal dominant inheritance means that the gene is located on one of the autosomes ( chromosome ... affected, and "dominant" means that only one gene is necessary to have the trait. Autosomal ...

Autosomal recessive

... Autosomal recessive inheritance means that the gene is located on one of the autosomes ( chromosome ... Requires that both parents carry traits for the gene in order for it to be passed to their offspring. ... who have received two copies of an autosomal gene , one copy from each parent. The ...

Breast Cancer

... intake of vegetarian diets. Breast cancer gene BRCA2: See: BRCA2. Common Misspellings: breast canser gene brca2 Search All of MedicineNet For: search help ... balanced diet s, ... Alterations in the RB1 gene have also been found in other tumor s, ...

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gene in Biological News

Mary had a lot of lambs: Researchers identify way to accelerate sheep breeding

... researchers have discovered an unusual form of a gene that prompts ewes to breed out of season as well ... caution that it may only be a marker for the gene actually responsible for the trait. "Breeding ... the phenotype the physical expression of the gene in the researchers' flock during a postdoctoral ...

Women often opt to surgically remove their breasts, ovaries to reduce cancer risk

... mutation carriers. BRCA1 and BRCA2 are hereditary gene mutations that indicate an increased risk for ... are widely used by carriers of BRCA1 and BRCA2 gene mutations to reduce the risk for breast and ovarian cancer. Evaluated by gene type, bilateral risk-reducing ...

Abnormal brain circuits may prevent movement disorder

... scans who had no disease and no mutations in the gene for dystonia. Dr. Eidelberg and his ... that patients and non-patients with the disease gene have the same underlying functional brain ... approximately 30% of people who carry the mutated gene called DYT1 will develop the involuntary ...

Understanding how weeds are resistant to herbicides

... want to spend two years culling to find that gene every time. This is a way that we can get all of ... it is resistant or not because we know the gene sequence and we know the mutation and the ... conserved. So if we have the sequence for the PPO gene in waterhemp you can use that information to get ...

Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols

... from retroviruses are useful tools for long-term gene transfer because they allow stable integration of ... an effective, alternative method for nonviral gene transfer that avoids the safety concerns ... the "Sleeping Beauty Transposon System for Stable gene Expression in Mouse Embryonic Stem Cells" from ...

UBC researchers find first-ever 'wanderlust gene' in tiny bony fish

... A gene previously associated with physical traits is ... from UBC's Dept. of Zoology have found that the gene may also be contributing to the fish's tendency ... adjusting to their surroundings the first time a gene associated with this type of behaviour has been ...

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gene in Biological Technology

Genomic Health Announces Second Quarter 2009 Financial Results and Business Progress

... Results from a study that summarized the gene signatures of male patients for whom the Oncotype ... that breast cancer in men displays similar gene signatures to female breast cancer. ... that there were significant differences in gene expression between triple negative breast cancer ...

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

... such as bone, including: (1) proprietary gene Activated Matrix(TM) or GAM(TM) delivery and ... with non-healing diabetic foot ulcers. The gene Activated Matrix technology allows for a broad ... for soft and hard tissue healing. The gene Activated Matrix technology platform is expected ...

Sangamo BioSciences Reports Second Quarter 2009 Financial Results

... protein (ZFP) technology for therapeutic gene regulation and modification. By engineering ZFPs ... factors (ZFP TF(TM)) that can control gene expression and, consequently, cell function. ... sequence-specific ZFP Nucleases (ZFN(TM)) for gene modification. The most advanced ZFP ...

Cardium Provides Update on Phase 2b Excellarate Clinical Study and Plans for Additional Tissue Repair Applications

... studies and applications of Tissue Repair's gene Activated Matrix(TM) or GAM(TM) technology for ... Company. "During the course of this landmark gene therapy trial, we have observed some remarkable ... is a collagen-based topical gel employing TRC's gene Activated Matrix(TM) that is designed to locally ...

Sangamo BioSciences Announces Second Quarter 2009 Conference Call and Webcast

... protein (ZFP) technology for therapeutic gene regulation and modification. By engineering ZFPs ... factors (ZFP TF(TM)) that can control gene expression and, consequently, cell function. ... sequence-specific ZFP Nucleases (ZFN(TM)) for gene modification. The most advanced ZFP ...

Canadian researchers discover gene related to the appearance of aging

... - Scientists in Atlantic Canada have found a gene that may play a role in skin aging. Researchers ... research, scientists were able to identify the gene responsible for CL2 in these patients, citing an ... many systems, including brain development." The gene is one of six novel discoveries made to date ...

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gene in Biological Products

GenoStat Inducible Expression System from Upstate

Description:... provides tightly regulated control of exogenous gene expression in mammalian cells and is capable of ... the chimeric bipartite nuclear receptor complex. gene expression levels are easily manipulated higher ... Expression System provides maximal levels of gene expression (often reaching fold induction levels ...
Company:Upstate

pPIC9K from Invitrogen

Description:... pPIC3.5K vectors carry the kanamycin resistance gene that confers resistance to Geneticin Reagent in ... that multiple copies of the kanamycin resistance gene and the gene of interest are integrated into the genome (1). ...
Company:Invitrogen

Gene Pulser/E. coli Pulser Cuvette Rack from Bio-Rad

Description:... The expertise that made the original gene Pulser apparatus and accessory modules the most ... system available has been applied in the gene Pulser II system, which features unique PulseTrac circuitry. The modular design of the gene Pulser II system has the dual advantages of using ...
Company:Bio-Rad

* Quick & Easy E. coli Gene Deletion Kit from Gene Bridges GmbH

Description:... with the kit which can be used to replace a gene on the E.coli chromosome. Red/ET recombination ... cassette for the replacement of the targeted gene allows the subsequent removal of the selection ... Flp expression plasmids can be purchased from gene Bridges. Multiple knockouts can be generated ...
Company:Gene Bridges GmbH

Helios Gene Gun Low-Pressure System, 100-120 V from Bio-Rad

Description:... The Helios gene gun low-pressure system, 100-120 V, is used for ... into cells. The system includes the Helios gene gun, helium hose assembly, helium regulator, ... prep station, syringe kit, tubing cutter, Helios gene gun optimization kit, low-pressure regulator, and ...
Company:Bio-Rad

Helios Gene Gun Kit from Bio-Rad

Description:... Includes gene gun unit, 5 O-rings, 5 barrel liners, 5 white ... cartridge extractor tool, 9 V battery The Helios gene gun is a convenient, hand-held device that provides rapid and direct gene transfer into a range of targets in vivo. The ...
Company:Bio-Rad

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gene in Biological Definition

Albinism

... links Lack of pigmentation The gene which results in albinism prevents the body from ... albinism, individuals inherit an "albinism gene " from both parents. Where an individual receives one albinism gene and one normal gene, that person will not show ...

Allele

... one of a number of alternative forms of the same gene occupying a given locus (position) on a chromosome . An example is the gene for blossom color in many species of flower - a single gene controls the color of the petals, but there may ...

Allele frequency

... population , or equivalently the richness of its gene pool . Allele frequency is defined as follows: Given a) a particular chromosome locus , b) a gene occupying that locus, c) a population of ... The frequencies of all the alleles of a given gene often are graphed together as an allele ...

Apoptosis

... carried out by human papillomaviruses (HPV), a gene called E6 is expressed in a product that ... (IFN-alpha/beta)induce transcription of the p53 gene , resulting in the increase of p53 protein level ... and ced-4 . Ron Ellis also identified a gene with an opposite effect: ced-9 . The product of ...

Barr body

... can be significant if different alleles of a gene are present on the different chromosomes; in some ... evidence suggests that the maternally inherited gene may be imprinted . It is thought that this ... of CpG sites . These changes help inactivate gene expression on the inactive X-chromosome and to ...

Biodiversity

... and the United States of America. If the gene is the fundamental unit of natural selection, ... . They study processes such as mutations, gene exchanges, and genome dynamics that occur at the ... genetic engineering , people are going through gene patenting , processes patenting, and a totally ...

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gene in Biological Dictionary

Y chromosome

... including humans. In mammals, it contains the gene SRY, which triggers testis development, thus ... In mammals, the Y chromosome contains the gene that triggers embryonic development as a male. ...... In mammals, the Y chromosome contains the gene that triggers embryonic ... A team of 40 ...

Viral oncogene

... gene. The protein encoded by the human REL gene is a member of the NF-κB family of transcription factors. The REL gene is amplified or mutated in several human B-cell ... The official name of this gene is "v-Ki-ras2 Kirsten rat sarcoma viral ...

Vesicle

... : cytoplasmic membrane-bounded vesicle [14310 gene products] ... GO:0030136 : clathrin-coated vesicle [396 gene products] ... GO:0030659 : cytoplasmic vesicle membrane [391 gene products] ... GO:0030120 : vesicle coat [200 .....

Untranslated RNA

... bushy ... 3'UTR RNA from Alpha-Tropomyosin gene Suppresses Tumor Activity. ... Expression of ... Regions of mRNAs Play a Role in Regulating gene Expression. ... JD: The 3' untranslated region ... ... Tumor Suppression by the Prohibitin gene 3' Untranslated Region RNA in Human Breast ...

Tumor suppressor

... tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its ... suppressor . genes. ... tumor suppressor gene ( ¦tümər sə′presər jēn ) ( cell and molecular ...

Tubulin

... encode a distinct isoform. ... The ß3- tubulin gene encodes a divergent isoform expressed in a ... polymerization. ... Zebrafish protein-coding gene LOC572064. Represented by 26 ESTs from 16 cDNA ... SIMILARITIES ... Norway rat protein-coding gene Tuba3a. Represented by 47 ESTs from 2 cDNA ...

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Other Contents
(Date:7/9/2014)... acute episodes of low back pain are not linked ... wind direction and precipitation. Findings published in Arthritis ... College of Rheumatology (ACR), indicate that the risk of ... or wind gusts, but was not clinically significant. ... everyone experiences low back pain at some point in ...
(Date:7/9/2014)... types of cancer sends the protein factories in our ... uncontrolled growth, new research suggests. , Scientists at The ... responsible for ratcheting up activity of the endoplasmic reticulum ... blocks cancer cells need to keep growing. , A ... the flow of messages to the endoplasmic reticulum telling ...
(Date:7/9/2014)... found that fecal transplantation is effective and safe for ... is the result of a study led by Colleen ... Gastrointestinal Medicine at The Women,s Medicine Collaborative. The study ... of print in the American Journal of Gastroenterology ... diff , has increased to epidemic proportions over the ...
(Date:7/9/2014)... DALLAS July 9, 2014 There has been ... at UT Southwestern Medical Center using MyChart, the online, ... radiology results, communicate with their healthcare providers, schedule appointments, ... number of patients actively using MyChart each ... each year increased more than 10-fold, according to a ...
(Date:7/9/2014)... of Allergy and Infectious Diseases (NIAID), part of ... early-stage clinical trial of CRS3123, an investigational oral ... ( C. difficile ) infection. CRS3123 (previously known ... C. difficile growth while sparing normal intestinal bacteria. ... to 30 healthy men and women ages 18 ...
Breaking Medicine News(10 mins):Health News:Low back pain? Don't blame the weather 2Health News:Signal may send cancer's cellular factories into overdrive 2Health News:Women's Medicine Collaborative examines safety of fecal transplant to treat C. difficile 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 3Health News:NIH launches Phase I clinical trial of novel drug to treat Clostridium difficile infection 2
(Date:7/9/2014)... Spanish National Cancer Research Centre (CNIO) have discovered that ... regulates cell division in stratified epitheliathose that form part ... oesophagus or the vaginain adult organisms. According to the ... Nature Communications , this factor could also play a ... epithelia of the oesophagus and skin. , The pluripotency ...
(Date:7/9/2014)... 9, 2014Biofuels derived from the oils produced by algae ... To achieve this goal, optimization of cost effective strategies ... systems, is needed. Sapphire Energy has developed an innovative ... algae cultivation systems, described in Industrial Biotechnology , ... The article is available on the Industrial Biotechnology ...
(Date:7/9/2014)... the prevalence of antibiotic-resistant illness, Case Western Reserve ... disabling disease: blocking bacteria,s access to iron in ... siderophore, a small molecule, captures iron from two ... as well as how the body launches a ... appear in a recent edition of The ...
Breaking Biology News(10 mins):CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms 2Controlling contamination in open algae ponds for biofuels 2Bacteria hijack plentiful iron supply source to flourish 2
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