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Ganglion in Medical News

Quark Pharmaceuticals Announces Data Indicating Potential Utility of QPI-1007 for Treatment of Glaucoma

... that QPI-1007 prevents progressive retinal ganglion cell (RGC) loss in an increased ocular pressure ... of QPI-1007 in two additional models of retinal ganglion cell (RGC) death - induced by optic nerve crush ... vision loss are caused by the death of retinal ganglion cells. While existing therapeutics are capable of ...

'Cool' New Treatment for Hot Flashes in Breast Cancer Survivors

... of the safety and efficacy of the stellate ganglion block in 13 breast cancer survivors. It is called ... on healthy menopausal women that the stellate ganglion block can effectively 'shut off' these troubling ... over time. If the effect of the stellate ganglion block on hot flashes and night awakenings did not ...

'Cool' new treatment for hot flashes in breast cancer survivors

... study of the safety and efficacy of the stellate ganglion block in 13 breast cancer survivors. It is called ... on healthy menopausal women that the stellate ganglion block can effectively shut off these troubling ... over time. If the effect of the stellate ganglion block on hot flashes and night awakenings did not ...

Mouse study: Real-time imaging device may improve surgery for congenital colon disease

... does not detect the presence or absence of ganglion cells themselves. Instead, the spectral signature ... although the entire colon can be involved. ganglion cells normally stimulate smooth muscle of the ... pathologist looks for the presence or absence of ganglion cells and other features. But this process may ...

5 Brown faculty elected to world's largest scientific body

... Specifically, he explores structural and functional diversity among the ganglion cells of the eye, the retinal neurons that communicate directly with the brain. Current research focuses on one very unusual type of ganglion cell that senses light directly. These neurons drive reflexive responses ...

Blind humans lacking rods and cones retain normal responses to non-visual effects of light

... mammals have an additional light-sensitive photoreceptor in the retinal ganglion cell layer (pRGCs) that is directly sensitive to light and is primarily ... effects were maximal in response to wavelengths of light that the retinal ganglion cells respond best to, and not the wavelength that the visual system ...

Growth factor TGF-B helps maintain health of retinal blood vessels

... tissue, and fluid was leaking out of the vessels, which does not happen when the vessels are functioning properly. These defects led to the death of ganglion cells (nerve cells in the innermost part of the retina) and a loss of visual function. According to D'Amore and Walshe, the demonstration of the ...

Experts examine causes, treatment and prevention of glaucoma

... Although scientists know progressive degeneration of retinal ganglion cells and their axons is the primary cause of glaucoma, researchers have yet to identify a way to stop or prevent the degeneration. The challenge ...

Protein Might One Day Prevent Blindness

... call neuro-protective, in that it has protective benefits on both the photoreceptor layer that gets damaged in macular degeneration as well as on the ganglion cell layer which is damaged by glaucoma. So this finding could actually turn out to be a major accomplishment, affecting a lot of patients down the ...

Quark Pharmaceuticals to Present at the 20th Annual Piper Jaffray Health Care Conference

... having a novel, proprietary structure covered by Quark's intellectual property. Data has validated its neuroprotective effects on dying retinal ganglion cells, a cause of blindness and glaucoma. About Quark Pharmaceuticals, Inc. Quark Pharmaceuticals, Inc. is a development-stage ...

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Ganglion in Medical Technology

Quark Pharmaceuticals Announces First RNAi Drug Candidate Having a Novel, Proprietary Structure Covered by Quark Intellectual Property

... of Quark's New RNAi Product on Dying Retinal ganglion Cells, a Cause of Blindness in Glaucoma ... QPI-1007's effectiveness in a model of retinal ganglion cell (RGC) death by optic nerve crush (ONC). In a ... caused by the selective degeneration of retinal ganglion cells. Our results suggest that QPI-1007 may be ...

Scientists Discover a Role for the Growth Factor TGF-beta in Maintaining Health of Retinal Blood Vessels

... tissue, and fluid was leaking out of the vessels, which does not happen when the vessels are functioning properly. These defects led to the death of ganglion cells (nerve cells in the innermost part of the retina) and a loss of visual function. According to D'Amore and Walshe, the demonstration of the ...

Vision Deficit in Retinitis Pigmentosa Mice Corrected with DNA Nanoparticles

... provide effective treatments for more complex disorders such as diabetic retinopathy, macular degeneration, and various diseases that injure ganglion cells and the optic nerve." "We are pleased by the promise of these results and look forward to moving these studies forward to a potential ...
Ganglion in Medical Products

Humphrey FDT Visual Field Instrument

Features:... WelchAllyn Frequency Doubling Technology isolates a subset of retinal ganglion cell mechanisms in the magnocellular (M-cell) pathway. These M-cells have large diameter fibers and comprise only 3% to 5% of all retinal ganglion cells. The damage of these cells in the disease process makes FDT ...
Company:Carl Zeiss Meditec, Inc.

Humphrey FDT Perimeter

Features:... WelchAllyn Frequency Doubling Technology isolates a subset of retinal ganglion cell mechanisms in the magnocellular (M-cell) pathway. These M-cells have large diameter fibers and comprise only 3% to 5% of all retinal ganglion cells. The damage of these cells in the disease process makes FDT ...
Company:Carl Zeiss Meditec, Inc.
Ganglion in Medical Definition

Ganglion cyst

... ganglion cyst Classification & external resources ... eMedicine orthoped/493 A ganglion cyst (also known as a bible bump ) is a ... Cause The exact cause of the formation of ganglion cysts is still unknown but they are thought to be ...
Ganglion in Medical Dictionary

Cysts

... , and risk factors: Text Continued Below ... ganglion cyst s What are ganglion Cyst s? ganglion is a Greek word that means "a knot of tissue ." ...

Ganglion cyst

... ganglion cyst s are noncancerous fluid-filled lumps ( ... at the base of the middle or ring finger. ganglion CYST MIGHT BE DUE TO BANQUET SERVER'S OCCUPATION ... banquet department who has developed a wrist ganglion cyst on the right hand . I've been in this ...

Ganglion

... ganglion cyst s are noncancerous fluid-filled lumps ( ... at the base of the middle or ring finger. ganglion - A ganglion is a fluid-filled cyst that forms from the ...

Aspiration

... works in that the fluid is removed which diminishes the bump. But, since ganglion s cysts are firmly attached to the joint or tendon covering from ... type of thyroid cancer it is. Surgery is another treatment for ganglion cyst s and is more reliable than aspiration in preventing recurrences. ...

Ganglioneuroma

... GANGLIONEUROMA - A tumor ( neuroma ) containing ganglion cells; often located in the hands, wrists, or tops of the feet. [ Med ... is a benign tumor called ganglioneuroma , which is formed by mature ganglion and nerve cells that do not grow out-of-control. About 40% of ...

Anatomy

... " Anatomy Descriptive and Surgical" by Henry Gray appeared in 1858. Little could Dr. "NON-TEXTBOOK ANATOMY " LIKELY CAUSE OF WRIST PAIN , ganglion CYST Question: I am a 29 year-old woman, and I have had this annoying problem since childhood. Mastectomy - series: Normal anatomy ...

Blood

... that contains most antibodies. Used in the temporary prevention of hepatitis a nd as treatment for disorders with antibody deficiencies. ganglion cyst A benign , knot-like, cystic tumor on a tendon sheath. BLOOD -BRAIN BARRIER: A barrier created by brain capillaries that prevents many ...

Carpal tunnel syndrome

... tunnel syndrome or low back pain , certain exercise s may be recommended. On other occasions it is just uncomfortable. As an adult I have had ganglion cyst s of the wrists occasionally. I've read about carpal tunnel syndrome , which doesn't seem to match my symptoms. What could be causing my wrist ...

Cilia

... fibres, postganglionic; parasympathetic ganglia; parasympathetic nerve ; parasympathetic nervous system; parasympathetic root of cilia ry ganglion ; ... Normally, fluid in the eye is made by structures behind the iris called the cilia ry processes. The fluid flows through the pupil and ...

Ehrlichiosis

... Ehrlichiosis is transmitted by ticks . Both human forms tend to develop about nine days after a tick bite. Ehrenritter; Ehrenritter's ganglion ; Ehret; Ehret's phenomenon; Ehringhaus compensator; Ehrlich; ehrlichia; Ehrlichia canis; ehrlichia chaffeensis; Ehrlichia ondiri; Ehrlichia platys; ...

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Ganglion in Biological News

Case Western Reserve University receives $1.66m grant from NIH for otoprotection research

... but preservation and a minimal density of spiral ganglion cells are required for an effective implant," said Zheng. Spiral ganglion cells are the cells that provide the sense of ... cochlea could promote the survival of the spiral ganglion neurons by release of neurotrophic substances or ...

Gene therapy restores vision to mice with retinal degeneration

... the light-sensitive protein melanopsin in retinal ganglion cells. These specialized neurons receive light ... normally produced in 1 percent of retinal ganglion cells was found in about 10 percent of ganglion cells in the treated eyes but not in eyes that ...

Mammals can be stimulated to regrow damaged inner retina nerve cells

... of specific growth factor stimulation on the proliferation of Mller glia cells. The researchers injected a substance into the retina to eliminate ganglion cells (a type of nerve cell found near the surface of the retina) and amacrine cells. Then by injecting the eye with epidermal growth factor (EGF), ...

Retina adapts to seek the unexpected, ignore the commonplace

... his co-authors examined neural signals in retinal ganglion cells, which convey visual images from the eye to ... The spatio-temporal receptive fields of retinal ganglion cells change after a few seconds in a new ... recorded neural signals from the animals' retinal ganglion cells, testing whether adaptation to a different ...

How Fruitflies Know It's Time for Lunch

... both in the mouth and in the pharynx and aim toward the subesophageal ganglion region of the fly's brain. How olfactory and gustatory signals influence ... extend to throat muscles—which is surprising because most subesophageal ganglion neurons have no connection to motor function. All together, these few hug ...

Scientists use gene transfer technology and common virus to block neuropathic pain

... a carrier to deliver GAD to the nucleus of nerve cells in the dorsal root ganglion near the spine. In previous studies, the researchers have confirmed that ... to deliver other neurotrophic factors and pain-suppressing drugs to spinal ganglion cells. But Fink says the effect of the GAD-expressing vector is ...

Scientists use gene transfer technology and common virus to block neuropathic pain in animals

... a carrier to deliver GAD to the nucleus of nerve cells in the dorsal root ganglion near the spine. In previous studies, the researchers have confirmed that ... to deliver other neurotrophic factors and pain-suppressing drugs to spinal ganglion cells. But Fink says the effect of the GAD-expressing vector is ...

The synapse is a shotgun

... create a detailed 3-D map of the synapse of a chick ciliary ganglion. This ganglion is a cluster of neurons that connect the brain to the iris of the eye. It ... evidence for a different concept of the synapse. "The image of this ganglion is not one of a simple synapse with a single release site, but multiple ...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

... were functional for the duration of the study. Scientists observed improvements including pupil response to light and response to light stimuli from ganglion cells, which form the circuitry to the brain. Swaroop explains that photoreceptors constitute "the first line of information capture in ...

Researchers discover way to make cells in the eye sensitive to light

... uses light at different wavelengths to regenerate itself. In some forms of hereditary blindness photoreceptors are lost entirely, but the retinal ganglion cells, the cells which signal to the brain, remain intact. The researchers believe that by activating the melanopsin, these cells may gain the ...

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Ganglion in Biological Technology

Rutgers neuroscience may hold key to hearing loss remedy

... and the nerves to which they attach the spiral ganglion neurons that connect to the brain are the pianos ... Our studies have revealed that spiral ganglion auditory neurons possess a rich complexity that ... in relative proportions transforms the spiral ganglion neurons into either fast-firing transmitters to ...

Brian Levy, OD, MSc, Named Chief Operating Officer of Danube Pharmaceuticals

... novel mechanisms of action to both lower intraocular pressure (IOP) and to provide direct neuroprotective benefits to the optic nerve and its retinal ganglion cells, providing a dual approach to glaucoma therapy not provided by any currently marketed product. DNB-001 has been tested in a Phase I clinical ...

Barrett Katz, MD, MBA, Named CEO of Danube Pharmaceuticals

... novel mechanisms of action to both lower intraocular pressure (IOP) and to provide direct neuroprotective benefits to the optic nerve and its retinal ganglion cells, providing a dual approach to glaucoma therapy not provided by any currently marketed product. DNB-001 has been tested in a Phase I clinical ...
Ganglion in Biological Products

Anti-Vesicular Monoamine Transporter 2 (VMAT2) Polyclonal Antibody, Unconjugated from CHEMICON

Description:... inhibitors. Higher molecular weight bands may represent glycosylated VMAT2 (2,3). VMAT2 has been localized in adrenal chromaffin cells, sympathetic ganglion cells, enterochromaffin-like cells of the stomach and in CNS ....
Company:CHEMICON

Rabbit Anti-NPY Y2 Receptor Polyclonal Antibody, Unconjugated from GeneTex

Description:... in both rat and mouse and appears to work better on mose tissue, although positive staining is seen in rat. For full characterizarion in dorsal root ganglion and spinal cord see: J Comp Neurol. 2005 Aug ....
Company:GeneTex
Ganglion in Biological Dictionary

Cone cells

... a carbohydrate-rich ... ... of amacrine and ganglion cells ... Visual acuity starts with cone ... to midget bipolar cell connections. Midget ganglion cells ... Cone cells are a type of cell ... cone signals pass through the retina to the ganglion cells is rather ... Conversely the cone ...

Ventral root

... Sympathetic trunk ... Aspects of the topic ventral - root are discussed in the following places at Britannica. Assorted References ganglia ( in ganglion (physiology) ) ... toward the central nervous system); efferent neurons (carrying motor impulses away from the central nervous system) are ...

Rod cells

... million rod cells in the human retina. ... Additionally, multiple rod cells converge on a single interneuron, collecting ... 6 ganglion cell (non- rod non-cone) photoreceptors. 7 See also. 8 Bibliography. 9 References ... In rod cells , these together are called ....

Optic nerve

... Hippocrates described optic nerve injuries in De Morbis Vulgaribus' as early as ... The optic nerve originates from the confluence of ganglion cell axons as they ... Optic nerve axons congregate into bundles as they pass through thelamina cribrosa. ... Optic Nerve Head Drusen. ...

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