Chemists create 'Superbowl' molecule; May lead to better health
...searcher says. Superbowl molecules are similar in function to buckyballs, the experimental soccer-ball shaped molecules also known as fullerenes (C60), which also show promise for drug delivery and other useful applications. Whereas a single buckyball is designed to hold either a single atom or a hydrogen mo...Bioartificial kidney under study at MCG
...s. Even the contrast medium needed to study kidney function can be toxic. "I have seen healthy people on antibiotics for urinary tract infections develop renal failure; that's not uncommon, but it's most dreaded in the critically ill patient," Dr. Szerlip says. ...Wisconsin scientists grow critical nerve cells
... in theory, replace dying motor neurons to restore function and alleviate the symptoms of disease or injury. Much sooner in the future, the advance will allow researchers to create motor neuron modeling systems to screen new drugs, says study leader Su-Chun Zhang, an assistant professor of anatomy and neurol...Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...esearchers made the discovery in searching for the function of PGC-1beta co-activator that was isolated in 200...-activator interacted physically and turned up the function of sterol responsive element binding proteins. These important parts of the mechanism activate many ......eracts with Upf1," she added. "This is a whole new function for Staufen1 that couldn't have been predicted from the studies in flies, even though a similar function may occur in flies." The team discovered that Staufen1 doesn't interact with other components of th...Anti-JIP 1 / 2 (SH3) Polyclonal Antibody, Unconjugated, Clone ZMD.177 from Invitrogen
...he JNK signaling pathway, and thus the scaffolding function of JIP1, may be fundamental to the progression of Alzheimers disease....pMIR-hU6-Luc, Human U6 Luciferase Control Vector from Mirus Bio Corporation
... are recommended because these restriction enzymes function with compatible buffers....Peptide Synthesis from Sigma-Genosys
...enosys makes no claims to the peptide's ability to function in the specific application of the customer....Ph.D. Peptide Display Cloning System from New England Biolabs
...acids have a deleterious effect on the infectivity function of pIII in phage vectors, this vector is suitable only for the display of short peptides. Included with the cloning vector is an insert extension primer as well as a detailed protocol for cloning a peptide libra...Human Primary Preadipocytes and Differentiated Adipocytes
... that induce, or are involved with, this important function of the mature adipocyte. Figure 4 Conclusions With Stratagenes new Human Predifferentiated Adipocytes and HumanDifferentiated Adipocytes, researchers have a new class of reagents with whichto study hum...New Mammalian Two-Hybrid System Detects Protein-Protein Interactions
...ll be extremely helpful in elucidating the in vivo function of newlydiscovered genes and, in turn, will aid in further understanding known proteinfunctions. One of the most powerful methods for studying protein-protein interactions isthe yeast two-hybrid system developed by Dr. Stanley Fields and colleagues....Assess the In Vivo Activation of Signal Transduction Pathways with PathDetect Reporting Systems
...ctivities. One approachfor determining the in vivo function of newly identified gene products, growthfactors, ...e cis-elementsand provide preliminary clues on the function of the gene product or the effectsof the stimulus. Together, these systems provide researchers with ...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
...e RNA binding domain, which is consistent with its function as the RNA-binding subunit of the editing enzyme. The C-terminal region of ACF (residues 304-586) was unique. Once we had the clone in hand, we were able to quickly establish that ACF is required for editing a...An Epitope Tagging Vector for Gene Expression in Mammalian Cells
...c epitope tags are small, not interfering with the function of the target protein, and highly immunore...st, versatile and reliable methodfor analyzing the function of gene products in vivo. Acknowledgments We would like to thank Denise Wyborski, Cathy Chang, Xu ...More to Garlic than warding of Dracula
..., reducing the risk of blood clots and stroke, and function as an antioxidant. However, not all studies have demonstrated a link between garlic and a lower risk for heart disease....Developmental, neurologic problems common in extremely preterm infants
...reland. Of these, 283 were assessed for neurologic function Based on their lower scores on the Mental and Psychomotor Development Indexes compared with a population mean, 19% were classified as severely disabled, while 11% were classified as having "other disability." In addition, 10% of the children had seve...Thyroid hormone treatment hastens recovery after cardiac surgery
....Children and adults with highly depressed thyroid function fare worse following cardiac surgery than patients with mildly lowered thyroid function. The Heidelberg group conducted a randomized, double-blind, placebo-controlled trial of 40 children, ages 2 days to 10.4 years, who were scheduled for surgery to......Researchers studied survival rates based on a lung function test, called forced expiratory volume in one second (FEV1).They performed the lung function test on a group of more than 550 men and more than 640 women who varied in age from 20 to 89 years a...Bench-Top Centrifuges--Basic Tools for the Small Lab
...centrifuge offers great flexibility because it can function as a microcentrifuge, a high-speed and a general-purpose centrifuge in one instrument. A similar Primo R (refrigerated) model is also available. Both devices are available with a wide choice of rotors and adapters for tubes from 0.2 to100 ml and both...Analyzers Offer Point-of-Care Lipid Panels
...ith various lipid panels and, in one device, liver function assessment as well. Cholestech Corporation, Haywar...L ratio, estimate of LDL and VLDL. Immediate liver function results are also available with the devices newly available ALT (Alanine Aminotransferase) testing c...Genetic Analysis Systems Enter the Clinical Mainstream
...a. This assay is used to assess the residual -cell function in patients treated with insulin, to distinguish between type 1 and type 2 diabetes, and various other diagnostic applications in patients with abnormal insulin secretion. The analytical sensitivity of the assay is typically better than 0.015 ng/mL (...Hemoglobin Testing at the Point of Care
... every second hour if the analyzer is on. This new function means that a control cuvette is no longer necessary, although one is still available as an accessory. The unbreakable, plastic microcuvette collects the exact amount of arterial or venous blood necessary (10 l). The cuvette cavity contains reagents d...Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
...oclonal antibody (IgG1 Mab) designed to inhibitthe function of a molecular structure expressed on the surface ofnormal and tumor cells called the epidermal growth factor receptor(EGFR, HER1, c-ErbB-1). In vitro assays and in vivo animal studieshave shown that binding of ERBITUX to the EGFR blocksphosphorylati...