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fragments in Medical News

Computer simulation captures immune response to flu

... inside the dendritic cell "present" protein fragments of the virus on the cell's surface for ... from the body, including the presentation of fragments of pathogenic proteins on the surface of ... by dendritic cells of disease-related protein fragments (antigens) to T cells more strongly impact ...

Parasites a key to the decline of red colobus monkeys in forest fragments

... McGill University in Montreal, surveyed 20 forest fragments near the western boundary of Kibale National ... density of potentially harmful parasites in these fragments to the undisturbed core forest of the park. ... four years, red colobus populations in forest fragments declined 20 percent, whereas populations of ...

Study reveals current multi-component vaccines may need reworking

... does this selectivity evolve? Does the process always focus on the peptid fragments that will provide the strongest immune response/protection? If not, can we ... not to the presence of a whole bacterium or virus, but instead to key fragments of those pathogens. Peptide-based vaccines are already used ...

4-in-1

... The peptide is present to specifically identify the cancer cells; the RNA fragments suppress the special cancer-cell genes, killing the cells. The magnetic ... RNAs) are introduced into the cell. These are short, double-stranded RNA fragments that bind specifically to the target mRNA. Inside the cell, a special ...

Urine Test for Heart Disease Shows Promise

... well in a small trial, German researchers report. The test looks for fragments of the protein collagen, which plays a major role in blocking heart ... and capillary electrophoresis, were used to find levels of 17 protein fragments that the researchers had identified as being associated with ...

PercSys Introduces Accordion CoAx(TM) Stone Control Device for Facilitating Percutaneous Kidney Stone Treatments

... to and fills the ureter in order to prevent the migration of stone fragments further down in the ureter during the fragmentation procedure. In this ... lithotripsy procedures to prevent the retrograde migration of stone fragments into the kidney. The 7mm and 10mm Accordion Stone Management Devices have ...

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fragments in Medical Technology

ESBATech's Antibody Fragment Enters Phase Ib/IIa in Ophthalmology

... feasibility of applying single-chain antibody fragments to the eye. With ESBA105, the people from ... therapeutic concentrations of ESBATech's antibody fragments with eye drops represents a major step forward in ... to stabilize monomeric, single-chain antibody fragments (scFvs) using its proprietary fully-human ...

ESBATech's Antibody Fragment Enters Phase I/IIa Clinical Development in Osteoarthritis with the Potential for Disease-Modifying Activity

... Development at ESBATech AG, added, "Antibody fragments have a number of advantages over whole ... to stabilize monomeric, single-chain antibody fragments (scFvs) using its proprietary fully-human ... development company focused on advancing antibody fragments for therapeutic applications. The Company applies ...

ESBATech Raises Additional CHF 23M (USD 22M), Extending Series B Venture Financing

... new drugs based on stable antibody fragments derived from fully human scaffolds. This is an ... added, "ESBATech's unique approach to antibody fragments derived from fully human scaffolds position them ... concentrations of its therapeutic antibody fragments to the targeted sites, in combination with ...

Xenomics Announces Issuance of a US Patent That Covers Use of Transrenal Nucleic Acid Technology for Infectious Disease Diagnostics and Monitoring

... Transrenal nucleic acids (Tr-DNA and Tr-RNA) are fragments of DNA and RNA from cells dying throughout the ... scientists have detected in urine DNA and RNA fragments of different pathogens, including viruses, ... from Xenomics were the first to report that fragments of DNA from normal cell death cross the kidney ...

ActiveSight and CHDI Leverage Fragment-Based Lead Discovery for Huntington Disease Therapies

... to the active sites of protein drug targets. The fragments are much smaller than the compounds used in ... using X-ray crystallography to visualize fragments that bind to the target. The fragments will then be linked or grown into larger, ...

Myelin Removal Beads: Premium Efficiency for Neural Cell Separations and Antibody Stainings

... system. During preparation of single-cell suspensions, myelin membrane fragments represent the major contaminant. "When dissociating adult neural tissue, ... other MACS Technology products", adds Dr. Biloune. "Contaminating myelin fragments can be depleted either by manual protocols or by automated magnetic ...
fragments in Medical Products

UltraPure™ Agarose 1000

Description:... for high resolution of small DNA RNA and PCR fragments <1000 bp. This standard melting temperature agarose can resolve DNA fragments with as little as 10 bp difference in size. ... resolution separation of DNA RNA and PCR fragments <1000 bp-Recovery of DNA RNA and ...
Company:Invitrogen

UltraPure™ Agarose

Description:... UltraPure™ Agarose resolves DNA and RNA fragments from 100 bp to >30 kb. UltraPure™ Agarose ... in:- -Analytical separation of DNA RNA and PCR fragments >1000 bp- Recovery of DNA RNA and PCR fragments >1000 bp- Southern and Northern blotting ...
Company:Invitrogen

Agarose-HR™

Description:... High Resolution - Efficiently separates DNA fragments from 50 to 1000 bp. It is useful for sizing PCR fragments, small DNA fragments generated by restriction enzyme digestion, and double-stranded RNA fragments generated by the MutationScreener™ ....
Company:Ambion, Inc.

Agarose - Separation >500 bp Genetic Performance Certified™

Description:... 100 bp 2.0%: 2000 - 50 bp Applications: *Separation of DNA or RNA fragments greater than or equal to 500 bp. *PCR analysis. *Recovery of separated DNA or RNA fragments from gel. *Blotting applications such as Southerns and Northerns. CAS # ...
Company:USB Corporation

UltraClean™ MS-8 Agarose

Description:... an agarose for molecular screening that improves resolution of small DNA fragments and PCR products. Its main features are: High resolution of PCR and DNA fragments with low base pairs. Improved clarity of the gel, enhancing visibility. ...
Company:Mo Bio Laboratories, Inc.

NuSieve® 3:1 Agarose

Description:... Performance testing of NuSieve 3:1 Agarose ensures fine resolution of DNA fragments up to 1,000 bp, though this agarose is capable of finely resolving DNA fragments ranging from 10 bp up to 1,500 bp. NuSieve 3:1 Agarose is designed for ...
Company:Cambrex

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fragments in Medical Definition

Thymocyte

... enzymes to clip the DNA and bring separate gene fragments together. The outcome of this process is that ... sequence, due to different choice of gene fragments and the errors introduced during the cutting and ... of the combinations of the T cell receptor gene fragments are non-functional. To eliminate thymocytes which ...
fragments in Medical Dictionary

Cutaneous

... tubelike instrument is passed through a small incision in the back to the kidney , where ultrasound breaks up the kidney stones . The stone fragments are then removed. Per cutaneous nephrolithotomy In this procedure, the surgeon makes a tiny incision in the back and creates a tunnel ...

Endometriosis

... There can be pain before, during or after one's period. The cause of endometriosis is unknown. One hypothesis is that the endometrial fragments move back up through the fallopian tube s rather than leaving the body with the menstrual flow. Diagnosis is by pelvic examination or laparoscopy ...

Fibrin

... clot . Normal value is less than 10 mcg/ml (micrograms per milliliter). Fibrin ogen is broken down by an enzyme called thrombin into short fragments of fibrin . Thrombin also activates a substance called Factor XII I. Fibrin : The protein formed during normal blood clotting that is the ...

Fracture

... the use of weights and pulleys to stretch and extend the muscle s around the hip . Fracture d bones may be seen. Foreign objects, such as fragments of metal or glass, may be seen. Abnormal growths ( tumor s) are seen. A fracture d sesamoid produces substantial swelling throughout the ...

Fungus

... does not make chlorophyll. Mushrooms, yeast s, and molds are examples. The plural is fungi. fusion protein ... The fungus is carried on fragments of skin or other particles that contaminate floors, mats, rugs, bed linens, clothes, shoes and other surfaces. Plastic shoes in particular provide ...

Ganglion

... II) are well-differentiated, slow-growing neuroepithelial tumor s comprised of neoplastic, mature ganglion cells, ... Torn, displaced, or loose fragments of soft tissue s (such as ligament s or cartilage ). Abnormal growths, cysts , or ganglion s. Evidence of joint or cartilage destruction ...

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fragments in Biological News

UMMS researchers publish DNA identification of czar's children

... doing so, they determined the gender of the bone fragments and recovered profiles of nuclear DNA, including ... who used as little as possible of the bone fragments in order to preserve the remains for proper ... found in the first grave. "The newly found bone fragments were fragile and difficult to work with, but we ...

Genome of a heat and drought resistant cereal plant analyzed

... multiple times and then shredded into many small fragments by squeezing the DNA through a pressurized syringe. Finally the fragments are sequenced from both ends ans subsequentially the millions of small DNA fragments are assembled by elaborate computational methods ...

A simple fusion to jump-start evolution

... thermodynamic barrier, by incubating short RNA fragments in water of different temperatures and pH. ... fragments, generally within 14 hours. The RNA fragments came together as double-stranded structures then joined at the ends. The fragments did not have to be the same size, but the ...

Superglue from the sea

... it might be used for gluing together small bone fragments in fractured knees, wrists, elbows, ankles and ... until they heal. We see gluing the small fragments back into the joint." In their study, Stewart ... difficult to maintain alignment of small bone fragments by drilling them with screws and wires. An ...

UI and ISU establish shared DNA sequencing instrumentation

... whereby hundreds of thousands of DNA fragments are sequenced concurrently to generate hundreds ... capable of sequencing relatively long DNA fragments of 200 to 500 bases. This instrument will be ... instrument that can sequence relatively short DNA fragments of 18 to 36 bases. The instrument is capable of ...

American Chemical Society's Weekly PressPac -- July 16, 2008

... July 21, 2008 Screening of tiny chemical fragments may pay big dividends in drug discovery ... instead sort through a few thousand tiny chemical fragments that bind weakly to their targets. After screening, these weakly-binding fragments are then expanded into more potent substances by ...

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fragments in Biological Technology

aTyr Pharma to Present at ChinaBio(R) Investor Forum in Hong Kong

... a novel platform of naturally occurring protein fragments that can be developed into biologic agents for ... are identifying a broad platform of protein fragments derived from human aminoacyl tRNA synthetases. ... of enzymes and reported the first evidence that fragments and splice variants of these proteins have latent ...

Dr. James Cai Joins aTyr Pharma to Drive Clinical Development in Asia

... discovering novel, naturally occurring protein fragments that can be developed into biologic agents for ... are identifying a broad platform of protein fragments derived from human aminoacyl tRNA synthetases. ... of enzymes and reported the first evidence that fragments and splice variants of these proteins have latent ...

Frost & Sullivan Recognizes ESBATech's Innovation in Developing Antibody Fragments for Biologic Therapeutics

... antibody that triggers immune responses, antibody fragments consist of only the naturally occurring ... for these novel biologics. "While antibody fragments are an appealing new therapy class, limitations ... optimizing highly-stable, single-chain antibody fragments (scFv) without any phage display." ...

ESBATech's Antibody Fragments Demonstrate Penetration into the Eye with Topical Delivery via Eye Drops

... has achieved high concentrations of its antibody fragments in all segments of the eye with topical delivery ... therapeutic concentrations of ESBATech's antibody fragments were observed in the anterior chamber (front of ... targets for topical ophthalmic use. Antibody fragments have a number of advantages over whole ...

Venter Institute Scientists Create First Synthetic Bacterial Genome

... of the native genome, the team specially designed fragments of chemically synthesized DNA to build ... The next step involved combining three 24kb fragments together to create 8 assembled blocks, each about ... two 1/8th fragments together to produce large fragments approximately 144,000 base pairs or 1/4th of the ...

String of fullerene pearls

... force microscope, the tiny structures look like fragments of nanoscopic pearl necklaces. In reality, the ... lined up like pearls. The researchers found fragments containing up to 35 pearls under the atomic force ... electron systems. This property could make these fragments interesting as a new starting material for more ...

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fragments in Biological Products

Agarose-HR from Ambion

Description:... High Resolution - Efficiently separates DNA fragments from 50 to 1000 bp. It is useful for sizing PCR fragments, small DNA fragments generated by restriction enzyme digestion, and double-stranded RNA fragments generated by the MutationScreener ....
Company:Ambion

GenElute Gel Extraction Kit from Sigma-Aldrich

Description:... of a spin or vacuum column format. DNA fragments of interest are extracted from slices of an ... run in either TBE or TAE buffer. Extracted DNA fragments selectively adsorb onto the silica membrane in ... the rapid purification of linear and plasmid DNA fragments from standard or low-melting agarose gels. This ...
Company:Sigma-Aldrich

Gel extraction kit from BioPioneer

Description:... which selectively adsorbs up to 10ug of DNA fragments in the presence of specialized binding buffers. ... oligos ( Application: * Recovery of DNA fragments from reaction solutions. * Recovery of DNA fragments from agarose gels. Features: * Quick and ...
Company:BioPioneer

UltraPure Agarose and SYBR Safe DNA Gel Stain combo from Invitrogen

Description:... and your institution Agarose resolves DNA and RNA fragments from 100 bp to >30 kb. UltraPure Agarose is a ... Analytical separation of DNA, RNA, and PCR fragments >1,000 bp Recovery of DNA, RNA, and PCR fragments >1,000 bp Southern and northern blotting ...
Company:Invitrogen

UltraPure Agarose and SYBR Safe DNA Gel Stain Combo from Invitrogen

Description:... and your institution Agarose resolves DNA and RNA fragments from 100 bp to >30 kb. UltraPure Agarose is a ... Analytical separation of DNA, RNA, and PCR fragments >1,000 bp Recovery of DNA, RNA, and PCR fragments >1,000 bp Southern and northern blotting ...
Company:Invitrogen

Fragment Library I: Large Volume with mixtures from ActiveSight

Description:... ActiveSight Fragment Library I consists of small fragments of "drug-like" molecules used to probe the ... of a protein binding site. The small size of the fragments allows "room to grow" through chemical ... -C(=O)(-CH3), -O-CH3, -C-OH The fragments can be used singly or as mixtures to decrease the ...
Company:ActiveSight

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fragments in Biological Definition

Antigen

... cells (APCs), and degraded into fragments. The fragments are then presented on the surface of APCs by ... viral or intracellular bacterial infection . The fragments are then presented on the cell surface in the ... CTL that do not react to normal body protein fragments are allowed to enter the bloodstream. ...

Bioinformatics

... instead the sequences of thousands of small DNA fragments (each about 600 nucleotides long). The ends of these fragments overlap and, aligned in the right way, make up ... data quickly, but the task to re-align the fragments can be quite complicated for larger genomes. In ...

Bioinformatics

... instead the sequences of thousands of small DNA fragments (each about 600 nucleotides long). The ends of these fragments overlap and, aligned in the right way, make up ... data quickly, but the task to re-align the fragments can be quite complicated for larger genomes. In ...

Polymerase chain reaction

... called base pairs . Certain methods can copy fragments up to 40 kb in size, which is still much less ... it with a DNA ladder , which contains DNA fragments of known size, also within the gel (Fig. 3). ... then amplifies them using PCR. The amplified fragments are then separated using gel electrophoresis. The ...

Restriction enzyme

... enzymes known as ligases , so that restriction fragments carved from different chromosomes or genes ... with complementary sequences enables two fragments to join or "to be spliced," which they tend to do ... enable molecular biologists to anticipate which fragments will join and how they will join--and to choose ...

Restriction fragment length polymorphism

... (PCR). The DNA is then chopped into restriction fragments by endonucleases , which only cut where there ... recognized by the enzymes. The restriction fragments are then separated according to length by ... varies between individuals: so the length of the fragments varies, and the position of certain gel bands ...

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fragments in Biological Dictionary

Seed coat

... or soften the seed coat . ... Seed coat fragments that remain in lint after. the ginning process decrease ... seed coat fragments affect not ... yielding fragile seed coat ... in the experimental cotton was ... seed coat fragments concluded that lint cleaning was ... ginning ...

Restriction fragment

... restriction digest A unique family of DNA fragments produced by digestion of a given DNA molecule ... nucleotides in one or more of the restriction fragments and is ... A restriction fragment length ... ... the DNA of an organism is digested (cut into fragments ) with a restriction ... Restriction ...

Okazaki fragments

... during DNA replication. The lengths of Okazaki fragments are between 1,000 to 2,000 nucleotides long in ... long in ... Okazaki fragments DNA sequences, 100 to 200 nucleotides long, ... lagging strand of ... The lengths of Okazaki fragments are between 1,000 to 2, ... Okazaki ...

Lagging strand

... during DNA replication. The lengths of Okazaki fragments are between 1,000 to 2,000 nucleotides long in ... as the lagging strand . ... reason why Okazaki fragments are created during lagging strand DNA ... newly synthesized DNA where ... As the Okazaki fragments are joined, the new lagging strand becomes ...

Genomic library

... biology, a library is a collection of DNA fragments that is stored and propagated in a population ... collection of cloned deoxyribonucleic acid fragments in a vector; includes all the genetic Library ... biology , a library is a collection of DNA fragments that is stored and ... Applications of genomic ...

Genomic clone

... offers the ability to clone large genomic DNA fragments of between 70-95 ... fractionated genomic DNA ... DNA CLONING (LEC 15) Is the cloning of fragments of CHROMOSOMAL DNA. ... ACs main use are in ... genomic cloning . ... If we want to clone fragments of genomic DNA which are even as small as 20kb ...

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