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Febrile in Medical News

Amgen Highlights Data to Be Presented at ASCO

... risk of mortality in cancer patients experiencing febrile neutropenia (neutropenia with fever) based on ... of mortality in patients with cancer experiencing febrile neutropenia Lead Author: Barron R ... the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid ...

Most babies with uncomplicated febrile seizures can avoid spinal tap

... in well-appearing children who have had a simple febrile seizure. Findings are published in the January issue of Pediatrics . Simple febrile seizures a generalized seizure lasting no more ... children 12 to 18 months old with a first simple febrile seizure and to "strongly" consider lumbar ...

U.S. Health Officials Back Off Preference for New MMRV Vaccine

... show that the MMRV shot increases the risk for febrile seizure in children aged 12 to 23 months. ... separate injections. But the absolute risk of febrile seizures is still low, experts stressed. "The ... so that they may see one [incidence of febrile seizure related to the vaccination] a year." ...

UC-Irvine scientists present groundbreaking research at Society for Neuroscience conference

... Can Help Identify Cognitive Deficits Following febrile Seizures UC Irvine epilepsy researchers have used ... cells marking the cognitive deficits following febrile seizures. This discovery shows for the first time ... might be at risk for brain dysfunction after long febrile ....

Study Showed ALIMTA(R) (pemetrexed for injection) Improved Survival in Certain Types of Non-Small Cell Lung Cancer

... neutropenia (5 vs 40); thrombocytopenia (2 vs 1); ALT elevation (3 vs 1); febrile neutropenia (2 vs 13); infection without neutropenia (6 vs 4); ... 3/4 neutropenia (1 vs 0); infection/febrile neutropenia - other (1 vs 0); febrile neutropenia (1 vs 0); fatigue (17 vs 13); thrombosis/embolism (6 vs 4); ...

ASCO Study Confirms Importance of Histology in Treatment of Non-Small Cell Lung Cancer With ALIMTA (pemetrexed for injection)

... neutropenia (5 vs 40); thrombocytopenia (2 vs 1); ALT elevation (3 vs 1); febrile neutropenia (2 vs 13); infection without neutropenia (6 vs 4); ... 3/4 neutropenia (1 vs 0); infection/febrile neutropenia -- other (1 vs 0); febrile neutropenia (1 vs 0); fatigue (17 vs 13); thrombosis/embolism (6 vs 4); ...

NCCN Updates Infection Guidelines to Include Information About H1N1 Virus (Swine Flu)

... with cancer. The H1N1 reference is located in the section of the NCCN Guidelines that lists recommendations for treating lung infiltrates in febrile neutropenic patients. The updated NCCN Guidelines note that certain tests and antiviral treatments that are effective in more common strains of ...

Therapy should extend beyond childhood

... through urine in this disease. In addition, intensive emergency treatment of the metabolism must be carried out to prevent a metabolic crisis during febrile infections. For their study, an international interdisciplinary research group of neuroradiologists and pediatricians headed by Dr. Stefan Klker ...

Cell Therapeutics Completes Pixantrone NDA Submission and Requests Priority Review

... event observed on the pixantrone arm was neutropenia in 41.2% of patients versus 19.4% on the comparator arm. However, the incidence of grade 3/4 febrile neutropenia was only 7.4% versus 3.0% in the comparator arm. Grade 3/4 infections had a similar incidence in both study arms (18% vs. 13%). Although ...

Prescription Copay Assistance for Patients taking Gleevec or Tasigna for Philadelphia chromosome-positive Chronic Myelogenous Leukemia (Ph+ CML)

... were thrombocytopenia (37%), neutropenia (37%), anemia (23%), and elevated lipase (17%). Other serious adverse reactions included pneumonia, febrile neutropenia, leukopenia, intracranial hemorrhage, and pyrexia (Grade 3/4: 2%). Dose adjustments or modifications Tasigna may need to be ...

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Febrile in Medical Technology

Preliminary PI-88 Phase 2 Prostate Cancer Results to be Presented at the American Society for Clinical Oncology (ASCO) 2008 Genitourinary Cancer Symposium

... early due to a higher-than-expected rate of febrile neutropaenia, a side effect involving a decrease ... is a clear demand for new therapies here. The febrile neutropaenia rates seen in this study ... control group. We have not seen evidence of febrile neutropaenia in our previous clinical experience ...

Lilly Files for European Approval of ALIMTA(R) (pemetrexed for injection) for First-Line Treatment of Non-Small Cell Lung Cancer

... thrombocytopenia, neutropenia. Common: febrile neutropenia and infection without ... neutropenia, and thrombocytopenia. Common: febrile neutropenia. Very rare: Thrombocythaemia. ... an increased incidence of infections. Fatigue and febrile neutropenia also occur more frequently with this ...

Preliminary Analyses from Phase 2 Genzyme Study Highlight Efficacy and Safety of Clofarabine in Older Adult AML Patients

... events occurring in more than 15 percent of patients included nausea, febrile neutropenia, vomiting, diarrhea and rash; most were grade 1 or 2. As ... effects including anemia, leukopenia, thrombocytopenia, neutropenia, and febrile neutropenia; and infection. Liver and kidney function should be assessed ...

Node-Negative Early Stage Breast Cancer Patients Benefit from Taxotere(R)-Based Chemotherapy

... severe event (24.6%) reported with the TAC regimen. The incidence of febrile neutropenia decreased to 6.5% with the use of G-CSF from the first cycle of TAC. The incidence of febrile neutropenia among patients treated with FAC was 2.3%. Grade 2-4 anemia was ...

Phase II Study of Zevalin(R) Consolidation Following Fludarabine and Mitoxantrone Chemotherapy Results in 100 Percent Complete Remission Rate and 89 Percent Three-Year Progression Free Survival in Patients with Previously Untreated Non-Follicular Indolent

... grade 4 in 5 patients and grade 3 in 13 patients. Only 1 patient developed febrile neutropenia. Following Zevalin administration grade 3-4 thrombocytopenia ... and 3 patients received platelet transfusions. Only 1 patient experience febrile neutropenia. The authors concluded "In this study we established the ...

Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine

... 4.6%). Commonly seen adverse events in the Taxotere-based regimen included febrile neutropenia (5.2%) and neutropenic infection (13.9%). The Tax 324 study ... cisplatin and fluorouracil (PF). Patients treated with TPF had more febrile neutropenia (12% vs 7%), neutropenic infection (12% vs 8%), and grade 3/4 ...

Responses After Completion of Therapy Increase Pixantrone Complete Remission (CR)/Unconfirmed Complete Remission (CRu) Rate to 24% and Overall Response Rate (ORR) to 40% Compared to 7% and 14% for Comparator Agents in Phase III EXTEND Trial in 3rd Line Th

... event observed on the pixantrone arm was neutropenia in 41.2% of patients versus 19.4% on the comparator arm. However, the incidence of grade 3, 4 febrile neutropenia was only 7.4% versus 3.0% in the comparator arm. Grade 3, 4 infections had a similar incidence in both study arms (18% vs. 13%). ...

Investigational Cancer Drug BSI-201 Showed Clinical Benefit in 62% of Patients with Triple-Negative Metastatic Breast Cancer and Significantly Prolonged Survival

... effects included neutropenia [25/57 in patients treated with GC and BSI-201; 31/59 patients treated with GC alone], thrombocytopenia and anemia. No febrile neutropenia was observed in patients receiving BSI-201 combined with chemotherapy. BSI-201 did not add to the frequency or severity of adverse events ...

Pixantrone Produces High Rates of Complete and Partial Remissions Even Among Aggressive NHL Patients With Extensive Prior Doxorubicin Treatment or Prior Rituximab Treatment

... event observed on the pixantrone arm was neutropenia in 41.2% of patients versus 19.4% on the comparator arm. However, the incidence of grade 3, 4 febrile neutropenia was only 7.4% versus 3.0% in the comparator arm. Grade 3, 4 infections had a similar incidence in both study arms (18% vs. 13%). ...

Induction Chemotherapy Followed by ChemoRadiotherapy Increased Time-to-Treatment Failure Compared to ChemoRadiotherapy Alone in Patients With Unresectable Locally Advanced Head & Neck Cancer

... treated with CRT alone (p=0.002). The most frequent severe (grade 3-4) adverse reactions were stomatitis (44% for IC+CRT vs. 31% for CRT) and febrile neutropenia (10% for IC+CRT vs. 1% for CRT). Other adverse events included neutropenia and asthenia. "These study results illustrate that this ...

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Febrile in Medical Products

Arctic Sun® 2000 Temperature Management System

Description:... Arctic Sun System rapidly induces mild hypothermia in those patients who would benefit from therapeutic hypothermia or rapidly reduces temperature in febrile patients. The Arctic Sun precisely monitors and maintains core body temperature in a range of 33C (91.4F) to 37C (98.6F). The Arctic Sun ...
Company:Medivance
Febrile in Medical Dictionary

Febrile seizure

... febrile seizure s are classified as simple or complex: Simple febrile seizure s. These are the most common. They last ... may cry, act confused, or be quite sleepy. febrile Seizure WHAT YOU SHOULD KNOW A ...

Febrile convulsions

... febrile convulsions Dr Trisha Macnair Very young ... developed. This can lead to fits , known as febrile convulsions , which are distressing to watch but ... fever -related seizures known as complex febrile convulsions . In such cases, there is a risk for ...

Febrile

... febrile seizure s are classified as simple or complex: Simple febrile seizure s. These are the most common. They last ... may cry, act confused, or be quite sleepy. febrile Seizure WHAT YOU SHOULD KNOW A ...

Grand mal

... Grand mal seizure A febrile seizure is a generalized tonic -clonic ( grand ... few minutes; or absence ( petit mal ), ... A febrile seizure may be diagnose d by the health care ... type seizures ) Partial complex seizure febrile seizure Generalized tonic -clonic seizure ( ...

Temporal lobe seizure

... to control with anti - seizure medication. febrile seizure Pregnancy : When you have epilepsy ... type seizures ) Partial complex seizure febrile seizure Generalized tonic -clonic seizure ( ... (focal) seizure Temporal lobe seizure febrile seizure (children) ... Temporal lobe ...

Generalized tonic

... (brief "loss of contact" type seizures ) Partial complex seizure febrile seizure Generalized tonic -clonic seizure ( grand mal ) Partial (focal) seizure Temporal lobe seizure febrile seizure (children) ... ...

Petit mal

... (brief "loss of contact" type seizures ) Partial complex seizure febrile seizure Generalized tonic -clonic seizure ( grand mal ) Partial (focal) seizure Temporal lobe seizure febrile seizure (children) ... Absence ( petit mal ): A blank stare lasting ...

Petit mal seizure

... (brief "loss of contact" type seizures ) Partial complex seizure febrile seizure Generalized tonic -clonic seizure ( grand mal ) Partial (focal) seizure Temporal lobe seizure febrile seizure (children) ... Absence or petit mal seizure : a short period ...

Seizures

... the brain that could be causing the seizures . Expected Duration ... febrile seizure s Powered by: This information is provided by an independent ... and/or regurgitated stomach contents. Convulsions with Fever ( febrile Seizure s) Crib Death (Sudden Infant Death Syndrome ) Croup CRS ...

Temporal

... (brief "loss of contact" type seizures ) Partial complex seizure febrile seizure Generalized tonic -clonic seizure ( grand mal ) Partial (focal) seizure Temporal lobe seizure febrile seizure (children) ... two parietal lobes at the sides control touch, ...

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Febrile in Biological News

NIH expands Human Microbiome Project; funds sequencing centers and disease projects

... immunodeficiency syndromes. Gregory A. Storch, M.D., Washington University School of Medicine, Saint Louis Nose, digestive tract and blood: febrile Illness $950,000 This team of investigators will examine if there is a relationship between the immune system and viral microbiome of groups of ...

Eribulin mesylate demonstrated anti-tumor activity in patients with advanced breast cancer

... 3 (severe) or Grade 4 (disabling or life- threatening) adverse events were neutropenia (a decrease in the number of granular white blood cells, 54%); febrile neutropenia, 5.5%, leukopenia (low white blood cell count, 14%), and weakness/fatigue (10%; no Grade 4 events). Grade 3 peripheral neuropathy (a ...

Influenza vaccine causes weaker immune response for children of rural Gabon than in semi-urban areas

... says van Riet. These studies indicate for the first time that influenza virus infections are frequent in Gabon, and suggest that many cases of febrile illness incorrectly diagnosed and mistreated as malaria may actually be due to influenza. In addition, these studies suggest that influenza ...

Fever causing headaches for Aussie parents

... for parents and the health professionals who give them information. "All parents should learn how to manage fever before their child's first febrile episode," she said. "Many parents see these medications as having magical qualities such as calming upset children, sedating them or lifting a ...

Molecular mechanism may explain how fevers spark seizures

... a molecular mechanism that could explain febrile seizures. The research, published March 1st in ... lead to new approaches for preventing recurrent febrile seizures in vulnerable children. febrile seizures affect as many as one in 15 children ...

'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens

... sample from a patient with a viral hemorrhagic fever (VHF)-like syndrome. Within six to eight days of infection, Marburg virus causes an acute febrile illness that frequently progresses to liver failure, delirium, shock, and hemorrhage. From October 2004 through July 2005, a Marburg outbreak in ...
Febrile in Biological Technology

Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin

... was generally well-tolerated at 48 and 60 mg/m2, with an incidence of febrile neutropenia of below 10%. An increase in febrile neutropenia is observed at 75 mg/m2, although the incidence remains below ...

FDA Approves IXEMPRA(TM) (ixabepilone), a Semi-Synthetic Analog of Epothilone B, for the Treatment of Advanced Breast Cancer

... with capecitabine, the overall frequency of Grade 3/4 adverse reactions, febrile neutropenia, serious adverse reactions, and toxicity related deaths was ... >3 x ULN is not recommended. With monotherapy, Grade 4 neutropenia, febrile neutropenia, and serious adverse reactions were more frequent in patients ...

Pixantrone Significantly Increases Complete Remissions, Overall Response Rates, Frequency of Durable Remissions and Progression Free Survival in Patients with Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

... event observed on the pixantrone arm was neutropenia in 41.2% of patients versus 19.4% on the comparator arm. However, the incidence of grade 3, 4 febrile neutropenia was only 7.4% versus 3.0% in the comparator arm. Grade 3, 4 infections had a similar incidence in both study arms (18% vs. 13%). Although ...

Naglazyme Approved by Brazil's National Health Surveillance Agency

... prior to the initiation of treatment. Consideration to delay Naglazyme infusion should be given when treating patients who present with an acute febrile or respiratory illness. Additional information can be found at www.naglazyme.com . About BioMarin BioMarin develops and commercializes ...

High-Dose Zevalin(R) With Tandem Stem Cell Infusion Produces 87 Percent Overall Survival in Relapsed/Refractory or High Risk Non-Hodgkin's Lymphoma

... non-hematologic toxicities were observed. Infections, none greater than grade 3, were noted in 8 patients (27 %) but hospitalization for grade 3 febrile neutropenia was required in only 3 patients. The authors concluded "the mild hematologic toxicity was unprecedented for a myeloablative regimen." The ...

Video: Higher Initial Dose of Gleevec Achieved Better Early Responses than Standard Dose for Patients with Chronic Myeloid Leukemia

... were thrombocytopenia (37%), neutropenia (37%), anemia (23%), and elevated lipase (17%). Other serious adverse reactions included pneumonia, febrile neutropenia, leukopenia, intracranial hemorrhage, and pyrexia (Grade 3/4: 2%). Dose adjustments or modifications Tasigna may need to be ...

First Taxane-Based Non-Anthracycline Containing Chemotherapy in Combination With Herceptin (TCH) for HER2 Positive Early Breast Cancer Patients Obtains Approval From the FDA

... significant difference in OS between the two experimental arms (TCH and AC-TH). Tolerance The most common adverse event was grade 3-4 febrile neutropenia (AC-T: 9.1%, AC-TH: 11.0%, TCH: 9.8%). Other common grade 3-4 adverse events included diarrhea (3.0% in the AC-T arm, 5.1% in the AC-TH ...

Naglazyme Approved by Japanese Ministry of Health

... prior to the initiation of treatment. Consideration to delay Naglazyme infusion should be given when treating patients who present with an acute febrile or respiratory illness. Additional information can be found at http://www.naglazyme.com . About BioMarin BioMarin develops and commercializes ...

Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2007 Financial Results

... patients had partial responses (two unconfirmed). -- SNS-595 has been generally well tolerated in this trial, with a low rate of febrile neutropenia or other Grade 3/4 adverse events and manageable Grade 1/2 nausea or vomiting. Based on the drug's observed safety profile ...

EMEA Accepts for Review Vidaza(R) Marketing Authorization Application for Higher-Risk Myelodysplastic Syndromes

... (35.0%), constipation (33.6%), neutropenia (32.3%) and ecchymosis (30.5%). Other adverse reactions included dizziness (18.6%), chest pain (16.4%), febrile neutropenia (16.4%), myalgia (15.9%), injection site reaction (13.6%), aggravated fatigue (12.7%) and malaise (10.9%). The most common adverse ...
Febrile in Biological Dictionary

Dengue fever

... Dengue fever and dengue hemorrhagic fever (DHF) are acute febrile diseases, found in the tropics, and caused by four closely related virus ... to certain regions, which means it is ... Dengue fever is a febrile illness that affects infants, young children and adults. ... Dengue / ...
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