Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
..., and the oils used to cook french fries and other fast food. Studies have shown that trans fats not only raise LDL levels in the bloodstream but lower high-density lipoproteins (HDL, or "good" cholesterol) and may have even stronger adverse effects than do saturated fats. The researchers report that whe...Timing is everything: First step in protein building revealed
... the ribosome complex, theresearchers examined how fast the pieces of the ribosome come together,and how long it takes them to fall apart under various circumstances.Their results support the idea that two separate steps take place oncethe instruction's starting point is found: first a structural change i...Research on Worms Yields Clues on Aging
...d wormscontinued to display the youthful traits of fast body movement and fastpumping of mouthparts during the latter phase of their extended lives.Further tests showed that the anticonvulsants stimulated transmissionof signals in nerves that control body movement.Scientists previously had found genetic m...The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life
... tissues in the past. The entire procedure is very fast and in a computer supported post-processing step, one or more stacks of images are assembled into a high-resolution film. Another advantage of SPIM is that the specimen is kept alive in a liquid-filled chamber, allowing scientists to track developme......xt of biomedicine, for example, they could provide fast and detailed analysis of blood samples in the physician's office without the need to wait several days before the sample has been returned from specialized laboratories. Other applications include customized chips for space travel in order to monitor...pMIR-mU6-Luc, Mouse U6 Luciferase Control Vector from Mirus Bio Corporation
... expression cassettes have the advantages of being fast to produce and test, some users may choose to transfectthe siRNA expression cassette in the form of a plasmid or to have a large supply of expression cassette DNA readily available. Any of thePCR products generated in the previous sections can be clo...pMIR-mU6, Mouse U6Template (Vector) from Mirus Bio Corporation
... expression cassettes have the advantages of being fast to produce and test, some users may choose to transfectthe siRNA expression cassette in the form of a plasmid or to have a large supply of expression cassette DNA readily available. Any of thePCR products generated in the previous sections can be clo...ELx50 Microplate Strip Washer from BioTek Instruments
The ELx50 is a fast and versatile automated strip washer which can come equipped with our patented Dual-ActionTM 16-channel manifold. This breakthrough design allows for independent control of the dispense and aspiration manifolds for overfill washing and overflow prote......ard laboratory hoods High-speed plate-feeding for fast washing, dispensing, reading, sealing, and labeling of microplates Automation of complete assays (cell-based, ELIZAs, mass spec., etc.) Expandable tracks to meet your research production needs as they grow Available modules with any combination of...Highest Possible Transformation Efficiencies for High-Throughput Applications
... exceptionally high transformation efficiencies, fast growth, blue-white color screening of reco... miniprep DNA. Simplified transformations, fast results, and ease of use make these cells ideal for all high-throughput cloning applications...Genotyping Single Nucleotide Polymorphisms with Molecular Beacons
...ers. This molecular beacons application provides a fast and simplemethod that can be performed in 2 hours in a 96-well format and is especiallysuitable for high-throughout, high-quality genotyping of SNPs. SNPs are the most frequently found DNA sequence variations in the humangenome (about 1 per 350 ......agenes PCR-Script cloning kits are outstanding for fast cloning of blunt-end PCR products, no matter what PCR enzyme is used to generate the inserts. Stratagene improved the kits to include the StrataPrep PCR purification kit and XL10-Gold ultracompetent cells. The StrataPrep kit allows PCR products to be...Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies
...mple. This assay ishighly sensitive and relatively fast (2 to 4 hours), but the required multistepoperations of the assay are labor-intensive. A plate reader, which is best forquantitating ELISA results, may be an investment that is prohibitive for somelaboratories. A rapid method of isotyping uses anti-......amplification. Conclusions This procedure allows fast genotyping of a large number of mice withlong-distance PCR using TaqPlus Long DNA polymerase. Usually, the resultsare ready the day after mice ear clipping. Additionally, by amplifying severalspecific overlapping fragments and analyzing these fragmen...Gujarat quake-Rescue teams give up hope of finding more survivors
...s of the Gujarat quake, from below the rubble, are fast giving up hope of finding any more survivors. They are now concentrating in clearing the rubble and saving the injured who have been lucky to be saved so far. A miracle baby was saved after nearly 90 hours under the rubble. The baby was 8 months old ...Oracle Corp. to help build world's first "Digital Hospital"
...20 to 125 million U.S. dollars.The project will be fast tracked and hopefully completed by 2003. From the moment a patient registers at the hospital, every blood test and MRI will be recorded in a central patient record, and pharmacy visits will be tracked. All charting will be done at the patient's bedsi...HIV did not arise from polio vaccine
... HIV started when rumours started flying thick and fast that HIV originated from the Wistar vaccine used in a 1950s anti-polio campaign in Africa. These vaccines were allegedly cultured in chimpanzee kidney cells. These chimp cells, some say, may have been contaminated with the virus that became HIV-1, th......veloped a calss of compounds that produce only the fast signals. Rats, given the new compound show up to 70% increase in bone strength. According to Kousteni it could even strengthen the bones in healthy people....... you age, your body cannot make new muscle protein fast enough and thereby lose muscle strength. Meanwhile a new study from the University of California shows that muscle protein is made as quickly as it is broken down in men over 70. In fact there is no difference in muscle protein turnover between older...Monitoring Patient Glucose Levels: New Advances in software make it easier
...rends over a day or a week, and this product gives fast access to information that can be used to identify..., gaining access to patient glucose readings is as fast as accessing a secure web page in many cases, and a physician can enter recommendations via the same...Hemoglobin Testing at the Point of Care
... on a single platform with selectable programs for fast HbA1c or HbA2/F/A1c reporting.The company says that the D-10 offers simple and efficient operation for clinics, physician offices or clinical laboratories. Device features include whole-blood primary tube sampling, which eliminates off-line sample pr...Stanford Researchers Find Brain Pathway of Depression in Rats
...rken again in response toelectrical activity, very fast high-resolution cameras capture theaction. The researchers can observe how different stimuli receivedby the animal, such as a dose of an antidepressant drug, affectcircuit operation. The researchers used slices of rat brain, Deisseroth said, "likea ...Trial Results with Intranasal Fentanyl Hold Promise for Treatment of Breakthrough Pain in Cancer
...this first in class novelformulation could provide fast onset of pain relief and shortduration of effect, ...episodeand provide tight control of the pain, i.e. fast but short-actingpain relief. The trial comparing intranasally with intravenously administeredfentan......icant clinicalproblem which requires a drug with a fast and reliable onset ofaction, together with ease of use and high patient acceptability.This study provides the first clinical evidence for Nasalfent as aneffective, acceptable and well-tolerated treatment and is also thefirst study to report clinicall...