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Failure in Medical News

Hill-Rom Reports Third Quarter Financial Results

... exposure to product liability or other claims, failure of the Company's announced or future strategic ... the spin-off of the funeral services business, failure to realize the anticipated benefits of the spin-off, failure of the Company to execute its acquisition and ...

Sunrise Reports Financial Results for Second-Quarter 2009

... of debt that is in default as a result of the failure to pay principal and interest to the lenders of ... debt that is in default as a result of Sunrise's failure to meet certain financial covenants . Sunrise ... a portfolio of communities owned by HCP, Inc. for failure to meet performance thresholds. On June 18, ...

Amgen and Wyeth Statement on FDA Announcement About Tumor Necrosis Factor (TNF) Blockers

... Have or have had hepatitis B Have heart failure Develop symptoms such as persistent fever, ... (some fatal); heart failure, including new heart failure or worsening of heart failure you already have ; allergic reactions ; immune ...

Cell Therapeutics Initiates Process to Obtain Marketing Approval for Pixantrone in Europe

... heart damage that may result in congestive heart failure many years later. As a result, there is a ... including, without limitation, the potential failure of pixantrone to prove safe and effective (including the failure to achieve the overall response rate, complete ...

Sunshine Heart Provides C-Pulse U.S. Clinical Update

... . About Advanced Heart failure Heart failure is a common condition in which the heart becomes ... million people in the United States have heart failure and it results in over 300,000 deaths each year. ...

MULTAQ(R) (dronedarone) for Atrial Fibrillation or Atrial Flutter Now Available in the United States

... is contraindicated in patients with severe heart failure (NYHA class IV) or NYHA Class II - III heart failure with a recent decompensation requiring hospitalization or referral to a specialized heart failure clinic. This unstable population corresponds to ...

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Failure in Medical Technology

National Cancer Institute Research Identifies Unique Mechanism of Brostallicin's Anti-Tumor Effectiveness

... including, without limitation, the potential failure of the preclinical results to predict results in clinical trials, the failure of the mechanism to be receptive to brostallicin's tumor cell killing profile, the failure of the bio-marker to guide clinical trials, the ...

Leading Experts Endorse Bioheart's Muscle Stem Cell MyoCell Therapy

... stem cell (myoblast) therapy for treating heart failure to mainstream use with FDA approval and CMS ... transplantation to patients with congestive heart failure and specifically to scar tissue (not living ... advantage over other cell types in treating heart failure as they can survive in low oxygen environments ...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... in patients with moderate or severe heart failure (NYHA Class III/IV), as well as in patients who ... heavy smoking. Worsening congestive heart failure (CHF) and increased mortality due to CHF have ... be used with caution in patients with mild heart failure and must be discontinued if new or worsening ...

West Wireless Health Institute Teams with Corventis for its First Multicenter, Randomized Clinical Trial

... to prevent hospital readmissions for heart failure SAN DIEGO, June 24 /PRNewswire-USNewswire/ ... ) Congestive heart failure is the leading reason for hospital admission in ... of Innovative Medicine. "Congestive heart failure is one of the largest and most problematic ...

New Therapy Found to Prevent Heart Failure

... demonstrated a 29 percent reduction in heart failure or death in patients with heart disease who ... end point - significant reduction in heart failure or death with CRT-D versus ICD-only. Cardiologist ... approved for use in patients with severe heart failure (New York Heart Association class III/IV), where ...

MADIT-CRT Trial Meets Primary Endpoint

... Scientific CRT-Ds slow the progression of heart failure in asymptomatic and mildly symptomatic patients ... 29 percent reduction (p=0.003) in death or heart failure interventions when compared to traditional ... eventually lead to a wider population of heart failure patients being treated with CRT-D therapy," said ...

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Failure in Medical Products

CardioSight Service

Description:... information applicable to the treatment of heart failure to help specialty physicians discern if the heart failure patients symptoms are stable or deteriorating. For example, heart failure physicians following patients with a Medtronic ...
Company:Medtronic Inc.

Maximo VR Model 7232

Description:... functions that help physicians manage heart failure patients who also experience atrial fibrillation. ... therapies48 The Medtronic exclusive Heart failure Management Report showing 14-month trends of key heart failure patient monitoring categories such as AT/AF ...
Company:Medtronic Inc.

InSync II Marquis™

Description:... functions that help physicians manage heart failure patients who also experience atrial fibrillation. ... detection. It also provides the exclusive heart failure management report, which shows 14-month trends of key heart failure patient monitoring categories like AT/AF burden, ...
Company:Medtronic Inc.

Insync Sentry™

Description:... thoracic fluid accumulation is a primary indicator of worsening heart failure and often results in patient hospitalization. The breakthrough feature ... systems and also to physicians who manage the ongoing care of heart failure patients. In the future, Medtronic plans to offer various methods to ...
Company:Medtronic Vascular

InSync III Cardiac Resynchronization System

Description:... The InSync III system also offers unmatched insight through key heart failure diagnostics and monitoring trends, to efficiently track a patient's ... indicated for the reduction of the symptoms of moderate to severe heart failure (NYHA Functional Class III or IV) in those patients who remain symptomatic ...
Company:Medtronic Inc.

Atlas II HF ICD Family

Description:... In patients indicated for an ICD, the Atlas II HF systems are also intended: to provide a reduction of the symptoms of moderate to severe heart failure (NYHA Functional Class III or IV) in those patients who remain symptomatic despite stable, optimal medical therapy (as defined in the clinical trials ...
Company:St. Jude Medical, Inc.

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Failure in Medical Definition

Atransferrinemia

... . The iron damage to the heart can lead to heart failure . The anemia is typically microcytic and ... hypothyroidism . Death may occur due to heart failure or pneumonia . Genetics ... on a 7-year-old girl who passed away from heart failure with atransferrinemia. The half-normal levels of ...

Pathology

... syndrome Other heart conditions Heart failure - Cardiomegaly - Ventricular hypertrophy ( ... Other Pneumothorax - Respiratory failure - Atelectasis - Mediastinitis ... disease - Cholestasis - Hepatitis - Liver failure - Cirrhosis - NASH - PBC - Budd-Chiari - ...

Muscle atrophy

... syndrome that is a co-morbidity of cancer and Congestive Heart failure ; Chronic Obstructive Pulmonary Disease ; burns, liver failure, etc. ... sarcopenia is unknown, but it may be due to a combination of the gradual failure in the " satellite cells " which help to regenerate skeletal muscle ...

Personalized medicine

... and further $1 billion to successfully market a new product. The failure rate of product development is very high and in many cases failure is not evident until a great proportion of this investment has been ...

Arterial stiffness

... stiffening. Increased aortic PWV has been shown to predict cardiovascular and in some cases all cause mortality in individuals with end stage renal failure (Blacher et al.,Circulation. 1999; 99: 2434–2439), hypertension (Laurent et al., Hypertension. 2001; 37: 1236–1241), diabetes mellitus (Cruickshank ...

Autoimmune regulator

... the development of a range of autoimmune diseases, the most common clinical conditions in the syndrome are hypoparathyroidism, primary adrenocortical failure and chronic mucocutaneous candidiasis. [1] AIRE is expressed primarily in the thymus. A gene knockout of the murine homolog Aire has created ...

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Failure in Medical Dictionary

Abdominal mass

... infant 's chest and lungs ) Weight loss or failure to gain weight (called failure to thrive ) Anemia (a low number of red blood ... in the urine high blood pressure kidney failure ... Symptoms include a change in bowel ...

Acute kidney failure

... Acute Kidney failure Overview The kidney s are a pair of small ... of by-products and toxins . Acute Kidney failure Decreased blood flow to the kidney s for a ... along the urinary tract . Acute kidney failure occurring without other cause in a person with ...

Acute renal failure

... Acute renal failure (if thrombosis occurs in a dehydrated child) ... your health care provider: ... Acute renal failure - In this form of kidney failure , the kidney s stop functioning properly because ...

Aldosterone

... diuretics used to treat congestive heart failure such as spironolactone or eplerenone ... ... normal cells, or other disorders, such as heart failure or kidney disease , cause the adrenals to ... of hypertension and congestive heart failure . aldosterone - an overproduction of the ...

Alport syndrome

... Atheroembolic renal disease Chronic renal failure Complicated UTI ( pyelonephritis ) Cushing's ... Atheroembolic renal disease Chronic renal failure Complicated UTI ( pyelonephritis ) Dementia ... Atheroembolic renal disease Chronic renal failure Complicated UTI ( pyelonephritis ) Dementia ...

Aplastic

... Aplastic anemia : Anemia due to failure of the bone marrow to produce blood cells, ... of the formed elements of the blood caused by a failure of the cell -generating capacity of the bone marrow . Aplastic anaemia - failure of the bone marrow , where red blood s cells ...

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Failure in Biological News

NIH announces new program to develop therapeutics for rare and neglected diseases

... these types of illness because of high costs and failure rates and the low likelihood of recovering ... drug from discovery to the marketplace. And the failure rate is high. "This initiative is really good ... This is also an expensive process, but the failure rate is lower at this stage. "NIH ...

Eating fatty fish once a week reduces men's risk of heart failure

... the association with the reduced risk of heart failure found in our study." A life-threatening ... pump enough blood to meet the body's needs, heart failure (also known as congestive heart failure) is ... blood pressure and coronary artery disease. Heart failure is the leading cause of hospitalization among ...

Ocera Therapeutics licenses novel treatment for acute hepatic encephalopathy from UCLB

... led by Professor Rajiv Jalan and the Liver failure Group at the Institute of Hepatology, UCL ... pressure in models of AHE in acute liver failure and cirrhosis. The data was published online in ... with AHE due to cirrhosis and acute liver failure will be carried out at University College ...

Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes

... contributing to the high incidence of heart failure after myocardial infarction in people with ... increased incidence and severity of heart failure following myocardial infarction in patients with ... lead to increased incidence and severity of heart failure following myocardial infarction. This is a major ...

While focusing on heart disease, researchers discover new tactic against fatal muscular dystrophy

... that a new class of experimental drugs for heart failure may also help treat the fatal muscular disorder. At first glance, heart failure and the muscle-wasting Duchenne disease couldn't ... their twenties. In people without Duchenne, heart failure typically starts much later in life, robbing the ...

UC Davis research shows that newly discovered drug reduces heart enlargement

... failure. "This holds promise to treat heart failure and other cardiovascular as well as kidney ... "The study of rat models showed that heart failure is driven by high angiotensin associated with ... progression of heart failure." Heart failure weakens the heart's pumping ability, she said. ...

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Failure in Biological Technology

Nile Therapeutics, Inc. Announces Dosing of First Patient in Phase 2 Study of CD-NP for the Treatment of Acute Heart Failure

... the development of novel therapeutics for heart failure patients, today announced dosing of its first ... for up to 72 hours in patients with acute heart failure and mild to moderate renal insufficiency. ... ability to relieve symptoms of acute heart failure and its effects on biomarkers of ...

DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD

... pivotal trial, namely median time-to-treatment failure through Day 50 (p-value 0.1177), orBec(R) did ... (p-value 0.005) and the median time to treatment failure through Day 80 (p-value 0.0226), as well as a 66% ... patients. The primary endpoint is the treatment failure rate at Study Day 80. This endpoint was ...

Palatin Technologies, Inc. Receives U.S. Patent Allowance for Heart Failure Drug Candidate

... A (NPRA), including PL-3994, Palatin's lead heart failure drug candidate. Palatin expects the patent will ... pharmacodynamic properties. About Heart failure Heart failure affects over 5.7 million people in the United ...

United States FDA Clears the REGEN Trial to Test Bioheart's Combination Gene and Stem Cell Therapy in Heart Failure Patients

... that help monitor, diagnose and treat heart failure and cardiovascular diseases announced today that ... implantation of MyoCell SDF-1 in congestive heart failure patients post myocardial infarction(s). ... to test this promising product candidate in heart failure patients after completing very successful ...

Novel gene found for dilated cardiomyopathy

... for heart muscle disease and chronic heart failure in some children and adults with dilated ... which is the most common cause of chronic heart failure in young people and the most common reason for ... About one in three cases of congestive heart failure is due to DCM, which also occurs in children. ....

Nile Therapeutics, Inc. To Raise $3.4 Million in Private Placement

... the development of novel therapeutics for heart failure patients, today announced that it has received ... for up to 72 hours in patients with acute heart failure and mild to moderate renal insufficiency. ... ability to relieve symptoms of acute heart failure and its effects on biomarkers of ...

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Failure in Biological Products

Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description:... measures of adiposity (e.g. body mass index (BMI) or percent body fat) demonstrates that leptin levels are elevated even in obese patients. The failure of these elevated leptin levels to alter the obese state of these individuals may be related to a leptin resistance and an inability of leptin to ...
Company:Diagnostic Systems Laboratories, Inc.
Failure in Biological Definition

Diabetes mellitus

... disease (doubled risk), chronic renal failure (it is the main cause for dialysis ), retinal ... from unnoticed type 2 diabetes, including renal failure , and coronary artery disease . Type 2 ... to microangiopathy ) which can lead to renal failure Large vessel disease complications: ...

Dialysis

... kidneys are incapable of this, i.e. in renal failure . Contents showTocToggle("show","hide") ... The decision to dialyse In acute renal failure , dialysis is generally initiated when the renal ... the body's physiology. In chronic renal failure (or end-stage ...

Colchicine

... and throat, fever , vomiting , diarrhea , abdominal pain and kidney failure . Death from respiratory failure can follow. There is no antidote. Laboratory use In laboratory ...

Human

... is prominently reflected in human culture. (See also food science .) failure to obtain food leads to hunger and eventually starvation , while failure to obtain water leads to dehydration and thirst . Both starvation and ...

Liver

... others. Less commonly, liver transplantation is done for fulminant hepatic failure , in which liver failure occurs over days to weeks. Liver allografts for transplant usually ...

Urea cycle

... in some genetic disorders ( inborn errors of metabolism ), and in liver failure . The result in liver failure is accumulation of nitrogenous waste, mainly ammonia, which leads to ...

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Failure in Biological Dictionary

Renal

... followed by toxemia ... Acute renal failure occurs in 5 percent of hospitalized patients. ... Once acute renal failure develops, supportive therapy is critical to maintain ... Acute renal failure is present in 1 to 5 percent of patients at ...

Post-meiotic segregation

... with meiotic recombination at HIS4. ... failure to repair the mismatch will result in a post ... segregation (PMS) is observed, indicting failure to ... chromosome maintenance; PMS, post - ... post - meiotic segregation (indicative of a failure ... however, an increase in post - meiotic ...

Nondisjunction

... Nondisjunction is the failure of chromosome pairs to separate properly during cell division. This could arise from a failure of homologous chromosomes to separate in meiosis I, or the failure of sister chromatids to separate during ...

Heart

... Artificial Hearts Work. How Congestive Heart failure Works. Prices: Heart Health Books ... (Click ... heart of hearts . See feelings. ... Heart failure Heart failure Classification and external resources The major ...

Vessel cell

... has the exact definition. Good luck! Yielding of the vessel cell wall can occur under the combination of tensile ... Hence the mode of failure of the vessel cell wall is a function of the material ... ... into specific cell types such as neurons and blood vessel cells, but they ...

Trophoblast

... Trophoblasts become inert during pregnancy and are completely ... failure of the trophoblast to invade sufficiently is ... Trophoblast (Cytotrophoblast, ... trophoblast ( ) n. The outermost layer of cells of ...

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(Date:10/18/2014)... of patients with undiagnosed, suspected genetic conditions, a certain ... higher molecular diagnostic yield than traditional molecular diagnostic methods, ... The study is being released to coincide with the ... sequencing, which sequences the protein­coding region of the genome ... in a cell or organism), has been rapidly applied ...
(Date:10/16/2014)... war on the human body. Battles are won, ... pancreatic cancer, this stalemate—known as tumor dormancy—can last ... a phenomena that is poorly understood. , ... of Salvatore Torquato, a Professor of Chemistry at ... tumor dormancy and the switch to a malignant ...
(Date:10/16/2014)... infections and worldwide claims the lives of 160,000 ... University have succeeded in developing a promising vaccination ... , Xavier Saelens (VIB/UGent): "We discovered a new ... development of a novel approach to vaccination against ... small children and elderly people." , RSV: ...
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