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Factor in Medical News

FDA Approves New 3000 IU Vial Size for Kogenate(R) FS, antihemophilic factor (recombinant)

... vial size of Kogenate(R) FS , antihemophilic factor (recombinant). The new vial size offers greater ... for safe reconstitution and fast recombinant factor VIII treatment in a small, tamper-evident box ... Kogenate(R) FS, antihemophilic factor (recombinant) , is a ...

Boehringer Ingelheim to Commence Phase III Study Investigating the Role of BIBW 2992 as First-Line Treatment for Non-Small Cell Lung Cancer (NSCLC) Patients with EGFR Mutations

... cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations. BIBW 2992 is the ... inhibits vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptors (PDGFR) and fibroblast ...

Advanced targeted therapies effective as first-line treatment for lung cancer

... OUTCOMES OF PATIENTS WITH EPIDERMAL GROWTH factor RECEPTOR (EGFR) MUTATIONS IN IPASS (IRESSATM PAN ... STUDY) (ABSTRACT # B9.5) An epidermal growth factor receptor (EGFR) is a protein found on the surface of cells to which an epidermal growth factor (EGF) binds. When an EGF attaches to an EGFR, it ...

Bcl6 gene sculpts helper T cell to boost antibody production

... is short for B-cell lymphoma 6, a transcription factor previously shown to be selectively expressed in ... of Bcl6 in the absence of transforming growth factor beta (TGF) to drive T cell differentiation into Tfh. "Not only is Bcl6 a transcription factor expressed by Tfh cells, it also has a major ...

Stayhealthy and Innovative Wellness Solutions Announce Partnership to Bring Innovation to the Workplace Wellness Market

... as overweight - excess body fat is the number one factor driving the incidence and severity of the most ... weight as a measure of health. The health risk factor lies in excess body fat, or the ratio of lean ... to losing weight, it is also a significant factor in everything from chronic headaches, fatigue, ...

Why African-Americans are at greater risk of hypertension and kidney disease

... believe that a heightened level a certain growth factor in the blood may explain why blacks have a ... level of a protein, called transforming growth factor B1 (TGF-B1), raises the risk of hypertension and ... in black patients, higher levels of the growth factor are correlated with lower renin activity -- an ...

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Factor in Medical Technology

Mayo Clinic Study Finds Earliest Evidence of Memory Decline in Middle-Aged People at Genetic Risk for Alzheimer's Disease

... that the carriers of a common genetic risk factor for Alzheimer's disease begin to have memory ... of the APOE e4 gene, the major genetic risk factor for developing Alzheimer's disease at older ages. ... they are accelerated by the major genetic risk factor for Alzheimer's disease," said Eric Reiman, M.D., ...

Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing

... with edoxaban(2) - an investigational oral factor Xa inhibitor - provides insights into why ... is an oral anticoagulant that directly inhibits factor Xa, a clotting factor in the blood. Daiichi Sankyo is developing ...

CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders

... --Orally Active Enhancer of Human Nerve Growth factor Has Demonstrated Promising Activity ... agent that enhances the effects of nerve growth factor (NGF). CeNeRx intends to initiate a Phase l ... (CIPN) later this year. "Nerve growth factor has long been of interest as a potential therapy ...

Bayer Announces Leukine(R) Data Presentations at 45th American Society of Clinical Oncology (ASCO) Annual Meeting

... with granulocyte-macrophage colony stimulating factor (GM-CSF, sargramostim) Lead ... Leukine(R) (sargramostim) is the only growth factor approved in the U.S. for use following induction ... indications, Leukine is the only myeloid growth factor approved to reduce the incidence of infections ...

Senesco Announces H1N1 Influenza Survival Test Results in Mice

... Mice treated with an siRNA against Senesco's factor 5A gene had a 52% survival rate as opposed to a ... mice) were administered Senesco's siRNA against factor 5A approximately 24 hours after infection and ... "These prototype studies have demonstrated that factor 5A is a promising candidate for future study in ...

Boehringer Ingelheim to Present New Phase II Clinical Data on Two Lead Oncology Compounds at ASCO 2009

... cancer (NSCLC) patients who have epidermal growth factor receptor (EGFR) mutations.(2) "Lung cancer ... dual inhibitor of the epidermal growth factor receptor (EGFR) and human epithelial receptor 2 ... inhibiting vascular endothelial growth factor receptors (VEGFRs), platelet-derived ...

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Factor in Medical Products

Coatest APC Resistance V Kit

Description:... sensitivity and specificity of the test for the factor V:Q506 mutation is obtained by prediluting the ... discriminate between heterozygous and homozygous factor V genotypes. It also allows for analysis of ... inherited APC resistance due to mutations in the factor V ....
Company:DiaPharma Group, Inc.

Rheumatoid Factor IgM

Description:... Hycor Biomedical Ltd Autostat™II Rheumatoid factor IgM enzyme linked immunosorbent assay (ELISA) specific for Rheumatoid factor IgM (RF IgM). Enzyme-linked immunosorbent assay ... determination of specific IgM Rheumatoid factor in human serum. The results of the RF IgM assay ...
Company:Hycor Biomedical Inc.

STA STACLOT PROTEIN S

Description:... Measurement of the Functional Protein S level based on theprincipal of factor Va Inhibition by STA© Analyzers. Lyophilized Human Plasma, free of Protein S; Human Activated Protein C, bovine factor Va, all ....
Company:Diagnostica Stago, Inc.

STA DEFICIENT II

Description:... Substrate Plasma for factor II Assay by STA© Analyzers. Freeze-dried human serum and absorbed bovine plasma, the latter providing factor V and fibrinogen to the test ....
Company:Diagnostica Stago, Inc.

STA DEFICIENT V

Description:... Substrate Plasma for factor V Assay by STA© Analyzers. Freeze-dried human plasma, artificially depleted of factor ....
Company:Diagnostica Stago, Inc.

STA DEFICIENT VII

Description:... Substrate Plasma for factor VII Assay by STA© Analyzers. Freeze-dried human plasma from which factor VII has been removed by selective ....
Company:Diagnostica Stago, Inc.

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Factor in Medical Definition

Cachexia

... is probably a role for inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) -which is also nicknamed cachexin for this reason-, ... 6 (IL-6), as well as the tumor secreted proteolysis inducing factor (PIF). Related malnutrition syndromes are kwashiorkor and marasmus , ...

Ultradian

... a defined biological nature, apparently stemming from a common genetic factor that leads to generational morbidity. Both twins studies, and general ... (Dr. Claudio Stampi is a sleep expert). Circadian Rhythms factor in Rapid-Cycling Bipolar Disorder. [4] Barrios C, Chaudhry TA, ...

Central tolerance

... sites. In the case of T cell central tolerance, additional sources of antigen are made available in the thymus by the action of the transcription factor AIRE . After exposure to self antigens, T cells and B cells become immunologically tolerant (non-reactive) in a number of ways : Negative ...

Medicine

... health care might allow or ban a parallel private market. The latter is described as single-payer system. Transparency of information is another factor defining a delivery system. Access to information on conditions, treatments, quality and pricing greatly affects the choice by patients / consumers ...

High Frequency Ventilation

... by using negative pressure in the thorax . Once positive pressure is applied, some degree of VILI is likely to occur. One major causative factor is the over stretching of the airways and alveoli . During mechanical ventilation, the flow of gas into the lung will take the path of least ...

Patient trade-off

... Access to valid empirical information is crucial for such decision making. However the individual’s feeling towards the subject in question is also a factor based on emotional values and theological positions rather than knowledge. An individual that does not care about a certain documented side effect of ...

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Factor in Medical Dictionary

Absorption

... K deficiency Coumadin (warfarin) therapy factor VII deficiency factor X deficiency factor II (prothrombin) deficiency ...

Antibody

... molecules called collectively RF, or rheumatoid factor , is complexed to the individual's own gamma ... antibody in the blood called the rheumatoid factor . Rheumatoid factor is present in the blood when the body reacts ...

Blood pressure

... blood pressure ( hypertension ) is a major risk factor for coronary artery disease that can be ... Higher than normal blood pressure could be a factor for walking difficulties later in life, ... conditions. High blood pressure is a factor in heart disease and stroke . This article ...

Congenital protein C

... - Drug -Induced Immune Thrombocytopenia - factor II Deficiency - factor V Deficiency - factor VII Deficiency ...

Factor II deficiency

... factor II deficiency Definition: factor II deficiency is a disorder of blood clotting ... resulting from a deficiency of prothrombin. factor II deficiency ...

Factor XII

... factor XII assay Definition: factor XII assay is a blood test to measure the activity of factor XII -- one of the substances involved in ...

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Factor in Biological News

Grant supports LSUHSC research on how like cell receptor systems determine very different functions

... molecules that assemble the pathway around growth factor receptors." The supplement was funded through ... movement and cell division activity of growth factor receptors as a novel phosphorylation target. ... that are dependent upon specific growth factor receptors, like some breast cancers in which the ...

Journal of Vascular and Interventional Radiology increases impact, international reach

... past five years, and the increase in its impact factor to 2.217 in 2008 ranks JVIR in the top half of 90 ... and experience," said Stainken. JVIR's impact factor is a direct measure of the number of times ... arterial disease, and its five-year impact factor is 2.956, based on citations in 2008 to items ...

UAB study reveals bone coupling factor key to skeletal health

... (UAB) have discovered a molecular coupling factor that helps bones grow and remodel themselves to ... drugs, the researchers said The coupling factor is a human protein called transforming growth factor beta-1, or TGF beta-1. Previously, scientists had ...

UT scientist receives hemophilia research award

... a shortage of a blood-clotting protein called factor VIII and current treatments include injections of synthetically-produced, replacement factor VIII. Symptoms include uncontrolled, sometimes ... immune systems that are resistant to replacement factor VIII and produce antibodies that attack the ...

Women with endometriosis need special care during pregnancy to avoid risk of premature birth

... has found that the condition is a major risk factor for premature birth, the 25th annual conference ... and need to receive ART, which is itself a risk factor for adverse pregnancy outcome. Among women ... ART 1.37. "Endometriosis appears to be a risk factor for preterm birth, irrespective of ART," said Dr. ...

Elsevier announces 2008 journal impact factor highlights

... announced the highlights of its journal impact factor performance in 2008. Elsevier overall saw 75% of ... editors and our societies. This year's impact factor growth is one indication of the hard work and ... some of the best in their fields." The impact factor is a measure of the frequency with which the ...

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Factor in Biological Technology

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

... a gene or DNA vector encoding for a growth factor or any therapeutic protein. The Gene Activated ... production of micro quantities of growth factor proteins or other therapeutic proteins based on ... level of protein required. Growth factor Gene Portfolio ...

Inspiration Biopharmaceuticals Presents Safety Data on IB1001, a Novel Recombinant Factor IX for the Treatment of Hemophilia at the International Society on Thrombosis and Haemostasis (ISTH) Annual Meeting

... on its lead product, IB1001, a novel recombinant factor IX product to treat patients with hemophilia B. ... models and compared to commercially available factor IX products. Results showed that IB1001 has an ... profile when compared to currently available factor IX products. "These results and the ...

Results From Neurotech's NT-501 Phase 2 Retinitis Pigmentosa Studies Demonstrate Consistent Biological Effect on Photoreceptors

... modified to secrete ciliary neurotrophic factor (CNTF). CNTF, a growth factor capable of rescuing and protecting dying ... modified to secrete ciliary neurotrophic factor (CNTF). CNTF is a ...

deCODE and Celera Partner to Expand use of deCODE Risk Markers for Heart Attack, Stroke and Diabetes

... of cardiogenic stroke. Testing for this risk factor provides a new means of identifying stroke ... in TCF7L2 are the most important genetic risk factor yet found for type 2 diabetes(4). ... 4. Grant, et. al., "Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 ...

VIRxSYS Publishes New Study on RNA Therapy

... proteins in animals. With one of these, factor VIII, they showed they could correct hemophilia A ... the principal protein in good cholesterol, and factor VIII, which makes the protein missing in patients ... instructed the liver to make the correct form of factor VIII instead of a mutated form. We also added an ...

Lentigen and Expression Therapeutics Sign Hemophilia Co-Development Agreement

... a biotechnology company specializing in factor VIII-based therapeutics, today announced a ... clotting disorder caused by a mutation in the factor VIII gene resulting in a deficiency of factor VIII protein. Lentigen and Expression ...

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Factor in Biological Products

Anti-Factor XII Light Chain Monoclonal Antibody, Unconjugated from QED Bioscience Inc.

Description:... antibody recognizes the light chain of human factor XII and at 100 nM inhibits 50% of factor XII activity. It may be used in ELISA to detect human factor XII and in coagulation assays. Product Category: ...
Company:QED Bioscience Inc.

Mouse Anti-Factor V Heavy Chain Monoclonal Antibody, Unconjugated from GeneTex

Description:... Mouse monoclonal to factor V Heavy Chain Immunogen: Purified human factor V. Specificity: This antibody reacts with the ... in the heavy chain of thrombin-cleaved human factor V. KD = 1.15 x 10 -10 ....
Company:GeneTex

Anti-Factor XIIIa Ab-2 Polyclonal Antibody, Unconjugated from Lab Vision

Description:... factor XIII in both reduced and non-reduced forms. It does not react with human factor XIII B-chain or human factor ....
Company:Lab Vision

Neural Stem Cell Expansion Kit - Neurosphere from R&D Systems

Description:... Two growth factors, human epidermal growth factor (EGF) and human fibroblast growth factor basic (FGF basic), are included to promote the ... and glia, as identified after growth factor withdrawal by staining with the antibodies Tuj1, ...
Company:R&D Systems

Neural Stem Cell Expansion Kit - Monolayer Plus from R&D Systems

Description:... & Development 10 :3129). Human fibroblast growth factor basic (FGF basic) is included to promote the in ... of neural precursors. Human epidermal growth factor (EGF) is also included and may be used for ... and glia, as identified after growth factor withdrawal by staining with the antibodies Tuj1, ...
Company:R&D Systems

Mouse Anti-RFC1 Monoclonal Antibody, Unconjugated, 1320 from GeneTex

Description:... to the p37 subunit of human Replication factor C expressed in E. coli. Reactivity / Specificity ... of RFC1 Background Information Replication factor C is a multisubunit, DNA polymerase accessory ... the 140-kD subunit of mouse replication factor C. The protein encoded by this cDNA showed 83% ...
Company:GeneTex

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Factor in Biological Definition

Apoptosis

... at each step of these pathways. Tumor necrosis factor ( TNF ), a 157 amino acid inter-cellular ... trigger events that activate the transcription factor nuclear factor kappa B (NF-κB), which induces the ...

Morphogenesis

... involved in morphogenesis are transcription factor proteins that determine the fate of cells by ... The Engrailed protein is a transcription factor (yellow in figure to left) that is expressed in ... transcription factor. If this transcription factor is damaged, the fly grows legs on its head ...

Morphogenesis

... involved in morphogenesis are transcription factor proteins that determine the fate of cells by ... The Engrailed protein is a transcription factor (yellow in figure to left) that is expressed in ... transcription factor. If this transcription factor is damaged, the fly grows legs on its head ...

Oncogene

... (permanently) active like the epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), vascular endothelial growth factor receptor (VEGFR), etc. Cytoplasmic tyrosine ...

Promoter

... and other small RNAs General transcription factor binding sites Proximal promoter Approximately -250 Specific transcription factor binding sites Distal promoter Anything ... independent) Specific transcription factor binding sites Promoters represent critical ...

Blood type

... describe blood types in humans are ABO and Rh factor . There are 46 other known antigens , most of ... expressed on the glycoprotein von Willebrand factor (vWF), which participates in hemostasis ... Another characteristic of blood is Rhesus factor or ...

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Factor in Biological Dictionary

Transcription factor

... the field of molecular biology, a transcription factor is a protein that binds to specific DNA ... ... Sp1 is a human transcription factor involved in gene expression in the early ... . ... Sp1 is a zinc-finger transcription factor that binds to the sequence 5' GGGCGG 3' ... ...

TATA box

... binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence ... box is one of the most important transcription factor binding sites. ... In addition to the TATA Box ... TATA Box Binding Protein is a transcription factor that binds to the minor ... and Wireframe of ...

Splicing factor

... found on chromosome 17. The resulting splicing factor is a protein of approximately 33 kDa. ASF SF2 ...... a b "Entrez Gene: SF3B1 splicing factor 3b, subunit 1, 155kDa" ... Molecular architecture of the multiprotein splicing factor SF3b. ... Human protein-coding gene SF1. ...

Spliceosome

... : spliceosome [529 gene products] ... ... factor 3B subunit 1 ( Spliceosome associated protein 155) (SAP155) (SF3b155) ... Splicing factor 3A subunit 3 ( Spliceosome associated protein ... Correlation coefficient. O14547 ... factor 3B subunit 2 ( Spliceosome associated protein ...

Small nuclear RNA

... analysis of the human TFIIB-related factor II protein reveals an essential role for the ...... U2 small nuclear RNA auxiliary factor 1 ... U2(RNU2) small nuclear RNA auxillary factor 1. 79.54(n) ... Complete information for ...

Sigma Factor

... A sigma factorfactor ) is a prokaryotic transcription initiation factor that enables specific binding of RNA polymerase ...

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Other Contents
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